STRINGSTRING
A0A316U1T5 A0A316U1T5 A0A316U251 A0A316U251 A0A316U4Y5 A0A316U4Y5 A0A316U502 A0A316U502 A0A316U6B2 A0A316U6B2 A0A316U702 A0A316U702 A0A316U897 A0A316U897 A0A316U8D3 A0A316U8D3 A0A316UBD5 A0A316UBD5 SUS1 SUS1 A0A316UI52 A0A316UI52 A0A316UII2 A0A316UII2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
A0A316U1T5RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. (472 aa)
A0A316U251Chromatin modification-related protein. (665 aa)
A0A316U4Y5RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. (508 aa)
A0A316U502Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. (3130 aa)
A0A316U6B2Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (506 aa)
A0A316U702Protein HIR; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family. (1006 aa)
A0A316U897E3 ubiquitin protein ligase. (856 aa)
A0A316U8D3Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (446 aa)
A0A316UBD5Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones. (731 aa)
SUS1Transcription and mRNA export factor SUS1; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex required for deubiquitination of [...] (103 aa)
A0A316UI52Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (514 aa)
A0A316UII2Chromatin modification-related protein. (367 aa)
Your Current Organism:
Pseudomicrostroma glucosiphilum
NCBI taxonomy Id: 1684307
Other names: CBS 14053, MCA 4718, Microstromatales sp. MCA4718, NRRL 66310, P. glucosiphilum, Rhodotorula sp. MCA 4718
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