STRINGSTRING
rpsS rpsS rplB rplB RY69_1399 RY69_1399 rplW rplW RY69_1388 RY69_1388 rplD rplD rplC rplC rpsJ rpsJ RY69_1350 RY69_1350 RY69_1347 RY69_1347 recO recO RY69_1328 RY69_1328 argC argC argB argB RY69_130 RY69_130 recN recN nadD nadD RY69_1273 RY69_1273 RY69_125 RY69_125 rpsA rpsA RY69_1231 RY69_1231 rpsI rpsI rplM rplM RY69_1196 RY69_1196 RY69_1170 RY69_1170 RY69_1169 RY69_1169 ychF ychF RY69_1151 RY69_1151 RY69_11 RY69_11 rpsD rpsD RY69_1066 RY69_1066 sufB sufB sufD sufD sufC sufC sufS sufS ybeY ybeY RY69_1043 RY69_1043 rplY rplY rpsT rpsT RY69_1028 RY69_1028 rpmG rpmG ptbA ptbA metE metE RY69_945 RY69_945 RY69_922 RY69_922 RY69_911 RY69_911 RY69_91 RY69_91 RY69_909 RY69_909 RY69_90 RY69_90 lysA lysA rplL rplL rplJ rplJ RY69_864 RY69_864 RY69_847 RY69_847 nfo nfo RY69_842 RY69_842 RY69_807 RY69_807 rpsB rpsB RY69_781 RY69_781 RY69_760 RY69_760 RY69_723 RY69_723 RY69_697 RY69_697 RY69_690 RY69_690 RY69_689 RY69_689 RY69_686 RY69_686 RY69_673 RY69_673 RY69_665 RY69_665 rpmB rpmB RY69_630 RY69_630 RY69_629 RY69_629 raiA raiA RY69_597 RY69_597 RY69_594 RY69_594 RY69_590 RY69_590 RY69_583 RY69_583 rplT rplT rpmI rpmI gap gap smc smc folC folC RY69_535 RY69_535 RY69_518 RY69_518 RY69_470 RY69_470 RY69_469 RY69_469 RY69_456 RY69_456 RY69_451 RY69_451 hup hup RY69_413 RY69_413 rplA rplA rplK rplK RY69_386 RY69_386 RY69_379 RY69_379 rpmE rpmE cgtA cgtA rplU rplU RY69_3 RY69_3 RY69_297 RY69_297 RY69_264 RY69_264 RY69_228 RY69_228 clpB clpB RY69_2223 RY69_2223 RY69_2205 RY69_2205 RY69_2191 RY69_2191 RY69_218 RY69_218 RY69_2175 RY69_2175 RY69_2173 RY69_2173 RY69_2159 RY69_2159 RY69_2133 RY69_2133 RY69_2114 RY69_2114 RY69_2108 RY69_2108 tadA tadA ptbA-2 ptbA-2 nagE nagE RY69_2090 RY69_2090 ispE ispE RY69_2065 RY69_2065 RY69_2064 RY69_2064 RY69_206 RY69_206 rpmH rpmH recF recF gyrB gyrB RY69_2 RY69_2 RY69_1990 RY69_1990 RY69_1987 RY69_1987 RY69_1980 RY69_1980 RY69_1946 RY69_1946 RY69_1915 RY69_1915 RY69_1903 RY69_1903 RY69_1902 RY69_1902 RY69_1901 RY69_1901 recR recR RY69_1885 RY69_1885 RY69_187 RY69_187 leuA leuA topA topA pepD pepD fhs fhs RY69_1836 RY69_1836 RY69_1835 RY69_1835 RY69_1824 RY69_1824 dnaB dnaB RY69_1812 RY69_1812 rnhA rnhA rpsF rpsF rpsR rpsR RY69_18 RY69_18 RY69_1786 RY69_1786 nth nth RY69_177 RY69_177 RY69_1760 RY69_1760 RY69_1750 RY69_1750 RY69_1725 RY69_1725 RY69_1678 RY69_1678 RY69_1675 RY69_1675 rpsO rpsO RY69_1663 RY69_1663 truA truA RY69_1655 RY69_1655 rpsP rpsP rplQ rplQ RY69_1647 RY69_1647 rpmF rpmF rpsK rpsK rplS rplS rpsM rpsM RY69_1617 RY69_1617 RY69_1615 RY69_1615 RY69_161 RY69_161 RY69_1586 RY69_1586 RY69_1584 RY69_1584 RY69_1581 RY69_1581 rplO rplO trxA trxA rpmD rpmD RY69_1549 RY69_1549 RY69_1547 RY69_1547 rpsE rpsE rplR rplR rplF rplF rpsH rpsH rpsN-2 rpsN-2 rplE rplE recQ recQ rplX rplX dnaG dnaG pdxS pdxS rplN rplN rpsQ rpsQ RY69_1457 RY69_1457 rpmC rpmC RY69_1447 RY69_1447 rplP rplP purD purD purF purF rpsC rpsC RY69_1428 RY69_1428 rplV rplV rpsL rpsL rpsG rpsG
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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rpsS30S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (92 aa)
rplB50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (276 aa)
RY69_1399Alcohol dehydrogenase. (347 aa)
rplW50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. (98 aa)
RY69_1388Transposase. (434 aa)
rplD50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. (218 aa)
rplC50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (213 aa)
rpsJ30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (102 aa)
RY69_1350Vitamin K epoxide reductase family protein. (239 aa)
RY69_1347Phosphotransferase enzyme domain protein. (543 aa)
recODNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. (239 aa)
RY69_1328Putative tetratricopeptide repeat-containing domain protein. (1123 aa)
argCN-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (321 aa)
argBAcetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (318 aa)
RY69_130L-iditol 2-dehydrogenase. (346 aa)
recNDNA repair protein RecN. (616 aa)
nadDPutative nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (242 aa)
RY69_1273Oxidoreductase, aldo-keto reductase family. (303 aa)
RY69_125Oxidoreductase, zinc-binding dehydrogenase family. (334 aa)
rpsA30S ribosomal protein S1. (491 aa)
RY69_1231Hydrolase, NUDIX family. (224 aa)
rpsI30S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family. (163 aa)
rplM50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (149 aa)
RY69_1196Hippurate hydrolase. (383 aa)
RY69_1170O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase. (438 aa)
RY69_1169ABC transporter, ATP-binding protein. (308 aa)
ychFGTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. (366 aa)
RY69_1151Cupin domain-containing protein. (204 aa)
RY69_11PTS system maltose-and glucose-specific EIICB component. (164 aa)
rpsD30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (208 aa)
RY69_1066Putative Holliday junction resolvase; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. (150 aa)
sufBFeS assembly protein SufB. (499 aa)
sufDFeS assembly protein SufD. (411 aa)
sufCFeS assembly ATPase SufC. (259 aa)
sufSCysteine desulfurase; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. (424 aa)
ybeYPutative rRNA maturation factor; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. (183 aa)
RY69_1043Putative CoA ligase. (677 aa)
rplY50S ribosomal protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily. (205 aa)
rpsT30S ribosomal protein S20; Binds directly to 16S ribosomal RNA. (86 aa)
RY69_1028Glutamate synthase [NADPH] large chain. (1523 aa)
rpmG50S ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family. (55 aa)
ptbAPTS system glucose-specific EIICBA component. (148 aa)
metE5-methyltetrahydropteroyltriglutamate- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (767 aa)
RY69_945IstB-like ATP-binding protein. (253 aa)
RY69_922Putative phage holin. (80 aa)
RY69_911Leucyl-tRNA synthetase. (134 aa)
RY69_91DNA and RNA helicase-like protein. (1206 aa)
RY69_909ParB-like protein. (472 aa)
RY69_90FHA domain protein. (451 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (540 aa)
rplL50S ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. (126 aa)
rplJ50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (173 aa)
RY69_864Type III restriction enzyme, res subunit. (862 aa)
RY69_847Hypothetical protein; Belongs to the SOS response-associated peptidase family. (230 aa)
nfoPutative endonuclease 4; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. (284 aa)
RY69_842Aminotransferase, class V domain protein. (274 aa)
RY69_807IstB-like ATP-binding protein. (261 aa)
rpsB30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. (279 aa)
RY69_781AMP-binding enzyme. (686 aa)
RY69_760DNA topoisomerase. (719 aa)
RY69_723DNA-binding helix-turn-helix protein. (229 aa)
RY69_697Hypothetical protein. (432 aa)
RY69_690Alpha-mannosidase. (1048 aa)
RY69_689ManA1. (1039 aa)
RY69_686IstB-like ATP-binding protein. (253 aa)
RY69_673IstB-like ATP-binding protein. (261 aa)
RY69_665Transposase. (100 aa)
rpmB50S ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family. (64 aa)
RY69_630Serine/threonine protein kinase. (707 aa)
RY69_629Acyltransferase. (236 aa)
raiARibosome-associated factor Y; Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth. (220 aa)
RY69_597Tyrosine recombinase XerC. (355 aa)
RY69_594Prephenate dehydratase. (322 aa)
RY69_590Cysteine desulfurase. (415 aa)
RY69_583Cobyrinic acid a,c-diamide synthase. (319 aa)
rplT50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. (127 aa)
rpmI50S ribosomal protein L35. (64 aa)
gapGlyceraldehyde-3-phosphate dehydrogenase, type I; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (352 aa)
smcSMC N domain containing protein; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1215 aa)
folCBifunctional protein FolC. (521 aa)
RY69_535Cobalt-zinc-cadmium resistance protein czcD; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. (314 aa)
RY69_518Alpha-1,3/4-fucosidase, putative. (478 aa)
RY69_470Replication-associated recombination protein A. (459 aa)
RY69_469DEAD/DEAH box helicase. (856 aa)
RY69_456ATPase involved in DNA repair. (481 aa)
RY69_451ATP-dependent chaperone protein ClpB; Belongs to the ClpA/ClpB family. (863 aa)
hupDNA-binding protein HU; Belongs to the bacterial histone-like protein family. (93 aa)
RY69_413Primosomal protein N'. (769 aa)
rplA50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. (230 aa)
rplK50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. (143 aa)
RY69_386Putative glutamate-cysteine ligase; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily. (425 aa)
RY69_379Putative CoA ligase. (618 aa)
rpmE50S ribosomal protein L31; Binds the 23S rRNA. (70 aa)
cgtAGTPase obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. (563 aa)
rplU50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. (102 aa)
RY69_3Transposase. (392 aa)
RY69_297Hypothetical protein. (404 aa)
RY69_264IstB-like ATP-binding protein. (261 aa)
RY69_228ABC transporter ATP-binding component. (211 aa)
clpBATP-dependent chaperone protein ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. (894 aa)
RY69_2223Putative 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase. (273 aa)
RY69_2205Transposase. (434 aa)
RY69_2191IstB-like ATP-binding protein. (253 aa)
RY69_218Putative phosphoserine transaminase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (376 aa)
RY69_2175Transposase. (434 aa)
RY69_2173ABC transporter, ATP-binding protein. (394 aa)
RY69_2159Extracellular solute-binding protein, family 1. (415 aa)
RY69_2133Macrolide-specific ABC-type efflux carrier MacB. (233 aa)
RY69_2114Transcriptional regulator, Sir2 family. (251 aa)
RY69_2108Raffinose-binding protein. (429 aa)
tadACytidine and deoxycytidylate deaminase family protein; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. (152 aa)
ptbA-2Glucose-specific phosphotransferase enzyme IIA component. (170 aa)
nagEPTS system, N-acetylglucosamine-specific IIBC component. (512 aa)
RY69_2090Lipopolysaccharide kinase. (470 aa)
ispE4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (315 aa)
RY69_2065Stage 0 sporulation protein J; Belongs to the ParB family. (421 aa)
RY69_2064Soj family protein. (322 aa)
RY69_206Putative tetratricopeptide repeat-containing domain protein. (733 aa)
rpmH50S ribosomal protein L34; Belongs to the bacterial ribosomal protein bL34 family. (44 aa)
recFDNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. (368 aa)
gyrBDNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (696 aa)
RY69_2Transposase. (392 aa)
RY69_1990Hypothetical protein. (135 aa)
RY69_1987Hypothetical protein. (74 aa)
RY69_1980Putative serine/threonine-protein kinase PrkC. (682 aa)
RY69_1946Chloride transporter, ClC family. (527 aa)
RY69_1915IS1602, transposase. (434 aa)
RY69_1903Type II/IV secretion system protein. (339 aa)
RY69_1902Flp pilus assembly protein. (162 aa)
RY69_1901Flp pilus assembly protein. (104 aa)
recRRecombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. (200 aa)
RY69_1885UDP-N-acetylglucosamine diphosphorylase. (302 aa)
RY69_187PTS system mannose-specific EIIBCA component. (696 aa)
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (638 aa)
topADNA topoisomerase; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA superc [...] (1016 aa)
pepDDipeptidase. (533 aa)
fhsFormate-tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. (505 aa)
RY69_1836ABC transporter, ATP-binding protein. (265 aa)
RY69_1835FMN-binding domain protein. (183 aa)
RY69_1824Dipeptidase A. (506 aa)
dnaBReplicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (486 aa)
RY69_1812Putative ubiquinone biosynthesis protein AarF. (606 aa)
rnhARibonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (365 aa)
rpsF30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA. (96 aa)
rpsR30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. (82 aa)
RY69_18ATP-binding protein of ABC transporter system. (268 aa)
RY69_1786Monoamine oxidase. (537 aa)
nthEndonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (222 aa)
RY69_177Protein RibF. (374 aa)
RY69_1760Leucyl-tRNA synthetase. (134 aa)
RY69_1750HNH nuclease. (97 aa)
RY69_1725Reverse transcriptase (RNA-dependent DNA polymerase). (411 aa)
RY69_1678Transposase, mutator-like family protein. (122 aa)
RY69_1675Methylated-DNA-protein-cysteine methyltransferase. (178 aa)
rpsO30S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome. (89 aa)
RY69_1663ABC transporter, ATP-binding protein Vexp2. (236 aa)
truAtRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (303 aa)
RY69_1655Aldo/keto reductase. (287 aa)
rpsP30S ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family. (149 aa)
rplQ50S ribosomal protein L17. (174 aa)
RY69_1647Cation efflux family protein. (302 aa)
rpmF50S ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family. (64 aa)
rpsK30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. (132 aa)
rplS50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. (121 aa)
rpsM30S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family. (125 aa)
RY69_1617L-ribulose-5-phosphate 4-epimerase. (46 aa)
RY69_1615AMP-binding enzyme. (607 aa)
RY69_16150S ribosomal protein L36. (37 aa)
RY69_1586IstB-like ATP-binding protein. (261 aa)
RY69_1584ISPsy20, transposase IstB. (253 aa)
RY69_1581IstB domain protein ATP-binding protein. (155 aa)
rplO50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (150 aa)
trxAThioredoxin; Belongs to the thioredoxin family. (123 aa)
rpmD50S ribosomal protein L30. (64 aa)
RY69_1549Phosphohydrolase (MutT/nudix family protein). (418 aa)
RY69_1547Hypothetical protein. (418 aa)
rpsE30S ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family. (242 aa)
rplR50S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (123 aa)
rplF50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (179 aa)
rpsH30S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (132 aa)
rpsN-230S ribosomal protein S14 type Z; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site. (61 aa)
rplE50S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (190 aa)
recQATP-dependent DNA helicase RecQ. (652 aa)
rplX50S ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit. (111 aa)
dnaGDNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (697 aa)
pdxSPyridoxal biosynthesis lyase PdxS; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (291 aa)
rplN50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (122 aa)
rpsQ30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (86 aa)
RY69_1457ATP-binding protein of ABC transporter system. (270 aa)
rpmC50S ribosomal protein L29; Belongs to the universal ribosomal protein uL29 family. (83 aa)
RY69_1447Glycolipid ABC exporter family, ATP-binding protein. (144 aa)
rplP50S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. (139 aa)
purDPhosphoribosylamine-glycine ligase; Belongs to the GARS family. (422 aa)
purFAmidophosphoribosyltransferase. (503 aa)
rpsC30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. (266 aa)
RY69_1428Uracil-DNA glycosylase family protein. (187 aa)
rplV50S ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. (119 aa)
rpsL30S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit. (123 aa)
rpsG30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. (156 aa)
Your Current Organism:
Bifidobacterium breve
NCBI taxonomy Id: 1685
Other names: AS 1.2213, ATCC 15700, B. breve, BCRC 11846, Bifidobacterium parvulorum, CCRC 11846, CCRC:11846, CCUG 18365, CCUG 30511 A, CIP 64.69, DSM 20213, HAMBI 558, LMG 11042, LMG:11042, NCAIM B.01820, NCFB 2257, NCIMB 702257, NCTC 11815
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