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| | kdpB | Potassium-transporting ATPase B chain; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily. (682 aa) |
| | msrQ | Sulfoxide reductase heme-binding subunit YedZ; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalyti [...] (199 aa) |
| | KLV65341.1 | Hypothetical protein. (1266 aa) |
| | nanT | Sialic acid transporter; Catalyzes the proton-dependent transport of sialic acid. Belongs to the major facilitator superfamily. Sialate:H(+) symporter (SHS) (TC 2.A.1.12) family. (496 aa) |
| | lptC | Lipopolysaccharide export system protein LptC; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family. (191 aa) |
| | KLV65386.1 | Inner membrane protein YrbG. (325 aa) |
| | KLV65421.1 | Tryptophan-specific transporter. (414 aa) |
| | KLV65444.1 | D-tagatose-1,6-bisphosphate aldolase subunit GatZ. (321 aa) |
| | KLV65445.1 | D-tagatose-1,6-bisphosphate aldolase subunit GatZ. (91 aa) |
| | mzrA | Modulator protein MzrA; Modulates the activity of the EnvZ/OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR. (127 aa) |
| | dsbI | Protein-disulfide oxidoreductase DsbI; Required for disulfide bond formation in some proteins. Part of a redox system composed of DsbI and DsbL that mediates formation of an essential disulfide bond in AssT. (225 aa) |
| | KLV65568.1 | Hypothetical protein. (546 aa) |
| | nupG | Nucleoside permease NupG; Broad-specificity transporter of purine and pyrimidine nucleosides. Driven by a proton motive force; Belongs to the major facilitator superfamily. Nucleoside:H(+) symporter (NHS) (TC 2.A.1.10) family. (418 aa) |
| | KLV65624.1 | Hypothetical protein. (248 aa) |
| | KLV65684.1 | Tryptophan permease. (416 aa) |
| | KLV65706.1 | Nickel/cobalt efflux system RcnA; Belongs to the NiCoT transporter (TC 2.A.52) family. (299 aa) |
| | lgt | Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. (291 aa) |
| | ftsB | Cell division protein FtsB; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. (103 aa) |
| | KLV65816.1 | Hypothetical protein. (192 aa) |
| | KLV65832.1 | Manganese/iron transport system permease; Overlaps another CDS with the same product name. (283 aa) |
| | KLV65833.1 | Manganese/iron transport system permease; Overlaps another CDS with the same product name. (287 aa) |
| | alaE | L-alanine exporter AlaE; Exports L-alanine; Belongs to the AlaE exporter family. (149 aa) |
| | KLV66097.1 | Hypothetical protein; Belongs to the NiCoT transporter (TC 2.A.52) family. (326 aa) |
| | KLV66121.1 | Hypothetical protein. (513 aa) |
| | cysZ | Protein CysZ; High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway; Belongs to the CysZ family. (253 aa) |
| | zipA | Cell division protein ZipA; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins. (328 aa) |
| | KLV66204.1 | Xanthosine permease. (418 aa) |
| | lpxP | Protein Ddg; Catalyzes the transfer of palmitoleate from palmitoleoyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)- (palmitoleoyl)-lipid IV(A); Belongs to the LpxL/LpxM/LpxP family. LpxP subfamily. (306 aa) |
| | KLV66348.1 | Major facilitator superfamily transporter. (392 aa) |
| | dedD | DedD protein; Non-essential cell division protein that could be required for efficient cell constriction. (220 aa) |
| | arnF | Undecaprenyl phosphate-alpha-L-ara4N flippase subunit ArnF; Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane; Belongs to the ArnF family. (128 aa) |
| | arnE | Undecaprenyl phosphate-alpha-L-ara4N flippase subunit ArnE; Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane; Belongs to the ArnE family. (111 aa) |
| | rcsC | Sensor histidine kinase RcsC; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane- associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB. (948 aa) |
| | rcsD | Phosphotransferase RcsD; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB. (889 aa) |
| | lpxT | Inner membrane protein YeiU; Involved in the modification of the lipid A domain of lipopolysaccharides (LPS). Transfers a phosphate group from undecaprenyl pyrophosphate (C55-PP) to lipid A to form lipid A 1- diphosphate. Contributes to the recycling of undecaprenyl phosphate (C55-P); Belongs to the LpxT phosphotransferase family. (237 aa) |
| | dld | D-lactate dehydrogenase; Catalyzes the oxidation of D-lactate to pyruvate. Belongs to the quinone-dependent D-lactate dehydrogenase family. (579 aa) |
| | KLV66625.1 | Signal transduction histidine-protein kinase BaeS. (467 aa) |
| | mdtD | Multidrug efflux system protein. (470 aa) |
| | KLV66738.1 | Cobalt transporter CbiQ. (225 aa) |
| | KLV66865.1 | Tyrosine-specific transporter. (403 aa) |
| | KLV66870.1 | Hypothetical protein. (473 aa) |
| | mrdA | Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. (645 aa) |
| | KLV66973.1 | High-affinity zinc uptake system membrane protein ZnuB. (261 aa) |
| | lpxM | Lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase; Catalyzes the transfer of myristate from myristoyl-acyl carrier protein (ACP) to Kdo(2)-(lauroyl)-lipid IV(A) to form Kdo(2)- lipid A. (354 aa) |
| | KLV66997.1 | Multidrug transporter EmrE. (110 aa) |
| | ftsI | Transpeptidase; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. (581 aa) |
| | nhaP2 | K(+)/H(+) antiporter NhaP2; K(+)/H(+) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. NhaP2 subfamily. (577 aa) |
| | KLV67123.1 | Sodium/proton antiporter ChaA. (366 aa) |
| | KLV67149.1 | Hypothetical protein. (278 aa) |
| | KLV67156.1 | Intracellular septation protein A; Involved in cell division; probably involved in intracellular septation; Belongs to the YciB family. (179 aa) |
| | lapA | Inner membrane protein YciS; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family. (102 aa) |
| | KLV67222.1 | Methyl-accepting chemotaxis protein III. (561 aa) |
| | mdtI | Spermidine export protein MdtI; Catalyzes the excretion of spermidine. (109 aa) |
| | mdtJ | Spermidine export protein MdtJ; Catalyzes the excretion of spermidine. (120 aa) |
| | KLV67438.1 | Hypothetical protein; Belongs to the NiCoT transporter (TC 2.A.52) family. (342 aa) |
| | dtpA | Dipeptide and tripeptide permease A; Proton-dependent permease that transports di- and tripeptides; Belongs to the PTR2/POT transporter (TC 2.A.17) family. DtpA subfamily. (501 aa) |
| | KLV64221.1 | Hypothetical protein. (105 aa) |
| | KLV64358.1 | Protease 4. (618 aa) |
| | KLV64374.1 | Inner membrane protein. (148 aa) |
| | mltG | Aminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. (340 aa) |
| | murJ | Integral membrane protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. (511 aa) |
| | lpxL | Lipid A biosynthesis lauroyl acyltransferase; Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A). (306 aa) |
| | mdtG | Multidrug resistance protein MdtG. (406 aa) |
| | KLV62756.1 | D-alanyl-D-alanine carboxypeptidase DacC; Belongs to the peptidase S11 family. (400 aa) |
| | tolR | Protein TolR; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolQ, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction. (142 aa) |
| | tolQ | Protein TolQ; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolR, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction. (230 aa) |
| | KLV62870.1 | Cytochrome bd-I ubiquinol oxidase subunit X. (37 aa) |
| | dtpD | Dipeptide permease D; Probable proton-dependent permease that transports dipeptides; Belongs to the PTR2/POT transporter (TC 2.A.17) family. DtpD subfamily. (493 aa) |
| | kdpA | Potassium-transporting ATPase A chain; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane. (559 aa) |
| | kdpC | Potassium-transporting ATPase C chain; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex. (188 aa) |
| | mrdA-2 | Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. (633 aa) |
| | mrdB | Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. (370 aa) |
| | tatE | Sec-independent protein translocase TatE; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA; Belongs to the TatA/E family. TatE subfamily. (67 aa) |
| | crcB | Protein CrcB; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family. (127 aa) |
| | entS | Enterobactin exporter EntS; Component of an export pathway for enterobactin. Belongs to the major facilitator superfamily. EntS (TC 2.A.1.38) family. (414 aa) |
| | KLV63222.1 | Drug efflux system protein. (398 aa) |
| | clcA | H(+)/Cl(-) exchange transporter ClcA; Probably acts as an electrical shunt for an outwardly- directed proton pump that is linked to amino acid decarboxylation, as part of the extreme acid resistance (XAR) response. Belongs to the chloride channel (TC 2.A.49) family. ClcA subfamily. (473 aa) |
| | ftsQ | Cell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. (277 aa) |
| | ftsW | Lipid II flippase FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. (414 aa) |
| | ftsI-2 | Peptidoglycan synthase FtsI; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. (588 aa) |
| | ftsL | Cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. (121 aa) |
| | kefC | Glutathione-regulated potassium-efflux system protein KefC; Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport. (620 aa) |
| | KLV63611.1 | Hypothetical protein; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family. (517 aa) |
| | KLV63613.1 | Tyrosine permease. (421 aa) |
| | KLV63700.1 | Translocation and assembly module TamB. (1258 aa) |
| | KLV63766.1 | Quaternary ammonium compound-resistance protein SugE. (105 aa) |
| | KLV63804.1 | Phosphonate ABC transporter, permease PhnE. (259 aa) |
| | actP | Cation/acetate symporter ActP; Transports acetate; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (549 aa) |
| | KLV63848.1 | Iron-citrate transporter transmembrane signal transducer. (318 aa) |
| | KLV63851.1 | Fe(3+) dicitrate transport system permease FecC; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. (332 aa) |
| | mscL | Large-conductance mechanosensitive channel; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell. (137 aa) |
| | kefB | Glutathione-regulated potassium-efflux system protein KefB; Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport. (601 aa) |
| | damX | Protein DamX; Non-essential cell division protein. (426 aa) |
| | ugpE | Sn-glycerol-3-phosphate transport system permease UgpE; Part of the binding-protein-dependent transport system for sn-glycerol-3-phosphate; probably responsible for the translocation of the substrate across the membrane. (281 aa) |
| | KLV62184.1 | Inner membrane protein YhhQ; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily. (221 aa) |
| | KLV62186.1 | Major facilitator superfamily transporter. (405 aa) |
| | KLV62216.1 | Dipeptide and tripeptide permease B; Overlaps another CDS with the same product name. (229 aa) |
| | KLV62217.1 | Dipeptide and tripeptide permease B; Overlaps another CDS with the same product name. (259 aa) |
| | wecH | Inner membrane protein YiaH; Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units. (331 aa) |
| | KLV62304.1 | L-lactate permease; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family. (551 aa) |
| | KLV62435.1 | Phosphate transport system permease PstA. (296 aa) |
| | wecA | Undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase; Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP-C55). (367 aa) |
| | wzzE | Lipopolysaccharide biosynthesis protein WzzE; Modulates the polysaccharide chain length of enterobacterial common antigen (ECA); Belongs to the WzzB/Cld/Rol family. (348 aa) |
| | wzxE | Protein WzxE; Mediates the transbilayer movement of Und-PP-GlcNAc-ManNAcA- Fuc4NAc (lipid III) from the inner to the outer leaflet of the cytoplasmic membrane during the assembly of enterobacterial common antigen (ECA); Belongs to the polysaccharide transport (PST) (TC 2.A.66.2) family. (416 aa) |
| | wzyE | Common antigen polymerase WzyE; Probably involved in the polymerization of enterobacterial common antigen (ECA) trisaccharide repeat units; Belongs to the WzyE family. (451 aa) |
| | KLV62505.1 | Protein RarD. (298 aa) |
| | tatA | Sec-independent protein translocase TatA; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. (84 aa) |
| | tatB | Sec-independent protein translocase TatB; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation. (182 aa) |
| | tatC | Sec-independent protein translocase TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. (263 aa) |
| | KLV60910.1 | Inner membrane protein. (259 aa) |
| | menA | 1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. (309 aa) |
| | ftsN | Cell division protein FtsN; Essential cell division protein that activates septal peptidoglycan synthesis and constriction of the cell. Acts on both sides of the membrane, via interaction with FtsA in the cytoplasm and interaction with the FtsQBL complex in the periplasm. These interactions may induce a conformational switch in both FtsA and FtsQBL, leading to septal peptidoglycan synthesis by FtsI and associated synthases. (301 aa) |
