STRINGSTRING
folE2 folE2 purC purC AMS31193.1 AMS31193.1 AMS31195.1 AMS31195.1 pgk pgk AMS33448.1 AMS33448.1 AMS31197.1 AMS31197.1 AMS31216.1 AMS31216.1 thiC thiC AMS33459.1 AMS33459.1 AMS31291.1 AMS31291.1 AMS31318.1 AMS31318.1 AMS31332.1 AMS31332.1 pyrB pyrB AMS31335.1 AMS31335.1 AMS33472.1 AMS33472.1 gmk gmk rpiA rpiA AMS33475.1 AMS33475.1 thiG thiG pyrE pyrE AMS31412.1 AMS31412.1 AMS31413.1 AMS31413.1 phnK phnK AMS31415.1 AMS31415.1 AMS31416.1 AMS31416.1 AMS31417.1 AMS31417.1 AMS31418.1 AMS31418.1 thiE thiE AMS33502.1 AMS33502.1 atpB atpB atpE atpE atpF atpF atpH atpH atpA atpA atpG atpG atpD atpD atpC atpC glmU glmU AMS33510.1 AMS33510.1 nadD nadD purH purH purD purD coaE coaE AMS31611.1 AMS31611.1 AMS31619.1 AMS31619.1 zwf zwf AMS33549.1 AMS33549.1 clsB clsB gpsA gpsA gpmA gpmA AMS31647.1 AMS31647.1 AMS31688.1 AMS31688.1 AMS31709.1 AMS31709.1 ispH ispH coaD coaD ipk ipk prs prs pyrC pyrC AMS33594.1 AMS33594.1 AMS31897.1 AMS31897.1 dcd dcd AMS33603.1 AMS33603.1 AMS31984.1 AMS31984.1 pyrG pyrG eno eno lpxK lpxK adk adk pfp pfp carA carA carB carB AMS32080.1 AMS32080.1 prpE prpE accD accD purF purF AMS32106.1 AMS32106.1 lpxH lpxH AMS33660.1 AMS33660.1 glpK glpK AMS33666.1 AMS33666.1 accA accA ndk ndk ispG ispG purA purA pgi pgi tdk tdk folD folD AMS32253.1 AMS32253.1 AMS33687.1 AMS33687.1 plsX plsX tmk tmk AMS32272.1 AMS32272.1 AMS32309.1 AMS32309.1 AMS32312.1 AMS32312.1 AMS32313.1 AMS32313.1 AMS32314.1 AMS32314.1 AMS33706.1 AMS33706.1 gmhA gmhA AMS32332.1 AMS32332.1 aceE aceE AMS32348.1 AMS32348.1 moaC moaC ispD ispD ispF ispF AMS32423.1 AMS32423.1 AMS32430.1 AMS32430.1 pyrD pyrD AMS32477.1 AMS32477.1 mobA mobA fdhD fdhD moaA moaA AMS32482.1 AMS32482.1 purK purK purE purE AMS32496.1 AMS32496.1 AMS32498.1 AMS32498.1 surE surE AMS32508.1 AMS32508.1 upp upp nadE nadE pdxH pdxH AMS32547.1 AMS32547.1 AMS32587.1 AMS32587.1 AMS33781.1 AMS33781.1 pyrF pyrF cmk cmk AMS32687.1 AMS32687.1 AMS33799.1 AMS33799.1 AMS32712.1 AMS32712.1 AMS32724.1 AMS32724.1 nnrE nnrE AMS32746.1 AMS32746.1 AMS32748.1 AMS32748.1 thiL thiL AMS32839.1 AMS32839.1 nadK nadK mogA mogA AMS32878.1 AMS32878.1 AMS32883.1 AMS32883.1 AMS32891.1 AMS32891.1 AMS33844.1 AMS33844.1 tpiA tpiA AMS33847.1 AMS33847.1 AMS33852.1 AMS33852.1 AMS32924.1 AMS32924.1 purL purL AMS32946.1 AMS32946.1 AMS32948.1 AMS32948.1 lpxA lpxA fabZ fabZ lpxD lpxD dxr dxr AMS32974.1 AMS32974.1 pyrH pyrH AMS32983.1 AMS32983.1 AMS33011.1 AMS33011.1 AMS33013.1 AMS33013.1 thyA thyA guaB guaB AMS33887.1 AMS33887.1 AMS33069.1 AMS33069.1 psd psd acsA acsA AMS33891.1 AMS33891.1 AMS33892.1 AMS33892.1 AMS33098.1 AMS33098.1 AMS33138.1 AMS33138.1 AMS33149.1 AMS33149.1 AMS33150.1 AMS33150.1 purM purM purN purN dut dut AMS33196.1 AMS33196.1 lpxC lpxC AMS33213.1 AMS33213.1 AMS33231.1 AMS33231.1 AMS33285.1 AMS33285.1 AMS33301.1 AMS33301.1 pdxA pdxA AMS33309.1 AMS33309.1 AMS33934.1 AMS33934.1 AMS33415.1 AMS33415.1 AMS33419.1 AMS33419.1 plsY plsY dxs dxs
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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co-expression
protein homology
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folE2GTP cyclohydrolase; Converts GTP to 7,8-dihydroneopterin triphosphate. (279 aa)
purCPhosphoribosylaminoimidazole-succinocarboxamide synthase; Catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (294 aa)
AMS31193.1Fructose-1,6-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (354 aa)
AMS31195.1Pyruvate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyruvate kinase family. (479 aa)
pgkPhosphoglycerate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phosphoglycerate kinase family. (399 aa)
AMS33448.1Nucleoside-triphosphate diphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (204 aa)
AMS31197.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (399 aa)
AMS31216.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (229 aa)
thiCThiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. (637 aa)
AMS33459.1Phosphoribosylpyrophosphate synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribose-phosphate pyrophosphokinase family. (294 aa)
AMS31291.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (275 aa)
AMS31318.1acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (455 aa)
AMS31332.1Dihydroorotase; Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides; Derived by automated computational analysis using gene prediction method: Protein Homology. (428 aa)
pyrBAspartate carbamoyltransferase catalytic subunit; Catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (325 aa)
AMS31335.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0301 (AlgH) family. (186 aa)
AMS33472.1Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (728 aa)
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (199 aa)
rpiARibose 5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (231 aa)
AMS33475.1Thiamine biosynthesis protein ThiS; Derived by automated computational analysis using gene prediction method: Protein Homology. (66 aa)
thiGThiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (269 aa)
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (215 aa)
AMS31412.1Phosphonate metabolism protein PhnM; Derived by automated computational analysis using gene prediction method: Protein Homology. (385 aa)
AMS31413.1Phosphonate ABC transporter ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (235 aa)
phnKPhosphonate C-P lyase system protein PhnK; Derived by automated computational analysis using gene prediction method: Protein Homology. (260 aa)
AMS31415.1Hypothetical protein; Catalyzes the breakage of the C-P bond in alpha-D-ribose 1- methylphosphonate 5-phosphate (PRPn) forming alpha-D-ribose. Belongs to the PhnJ family. (305 aa)
AMS31416.1Carbon-phosphorus lyase complex subunit PhnI; Required for the use of phosphonate and phosphite; Derived by automated computational analysis using gene prediction method: Protein Homology. (363 aa)
AMS31417.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (198 aa)
AMS31418.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (150 aa)
thiEHypothetical protein; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (241 aa)
AMS33502.1Phosphomethylpyrimidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (304 aa)
atpBATP synthase F0F1 subunit A; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family. (264 aa)
atpEHypothetical protein; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (88 aa)
atpFATP synthase subunit B; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (156 aa)
atpHHypothetical protein; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (177 aa)
atpAATP F0F1 synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. (515 aa)
atpGATP F0F1 synthase subunit gamma; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (287 aa)
atpDATP synthase F0F1 subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. (473 aa)
atpCHypothetical protein; Produces ATP from ADP in the presence of a proton gradient across the membrane. (136 aa)
glmUHypothetical protein; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (459 aa)
AMS33510.1Septum formation inhibitor Maf; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. (204 aa)
nadDHypothetical protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (192 aa)
purHPhosphoribosylaminoimidazolecarboxamide formyltransferase; Involved in de novo purine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (522 aa)
purDPhosphoribosylamine--glycine ligase; Catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GARS family. (423 aa)
coaEHypothetical protein; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (208 aa)
AMS31611.1Gentisate 1,2-dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (337 aa)
AMS31619.1Acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (79 aa)
zwfGlucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (491 aa)
AMS33549.1Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (279 aa)
clsBHypothetical protein; Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. (384 aa)
gpsAGlycerol-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (333 aa)
gpmAPhosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (249 aa)
AMS31647.1Molybdopterin biosynthesis protein MoeB; Derived by automated computational analysis using gene prediction method: Protein Homology. (265 aa)
AMS31688.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (277 aa)
AMS31709.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribF family. (340 aa)
ispH4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (316 aa)
coaDPhosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (161 aa)
ipk4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (281 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (316 aa)
pyrCDihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. (343 aa)
AMS33594.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (173 aa)
AMS31897.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (224 aa)
dcdDeoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. (188 aa)
AMS33603.1Ribonucleotide-diphosphate reductase subunit beta; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (381 aa)
AMS31984.1acetoacetyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (670 aa)
pyrGCTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (562 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (427 aa)
lpxKHypothetical protein; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (378 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (217 aa)
pfp6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (423 aa)
carAHypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarA family. (386 aa)
carBCarbamoyl phosphate synthase large subunit; Four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; Derived by automated computational analysis using gene prediction method: Protein Homology. (1077 aa)
AMS32080.1Dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (396 aa)
prpECatalyzes the formation of propionyl-CoA using propionate as a substrate; PrpE from Ralstonia solanacearum can produce acetyl-, propionyl-, butyryl- and acrylyl-coenzyme A, and Salmonella enterica produces propionyl- and butyryl-coenzyme A; not expressed in Escherichia coli when grown on propionate/minimal media; ATP-dependent; Derived by automated computational analysis using gene prediction method: Protein Homology. (630 aa)
accDacetyl-CoA carboxylase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (295 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (508 aa)
AMS32106.1Glycosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (311 aa)
lpxHHypothetical protein; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (236 aa)
AMS33660.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HpcH/HpaI aldolase family. (288 aa)
glpKGlycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (499 aa)
AMS33666.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (178 aa)
accAacetyl-CoA carboxylase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (327 aa)
ndkNucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (141 aa)
ispG4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (425 aa)
purAAdenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (433 aa)
pgiHypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GPI family. (506 aa)
tdkThymidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (188 aa)
folDHypothetical protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (293 aa)
AMS32253.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (1257 aa)
AMS33687.1Septum formation inhibitor Maf; Nucleoside triphosphate pyrophosphatase that hydrolyzes 7- methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids; Belongs to the Maf family. YceF subfamily. (200 aa)
plsXPhosphate acyltransferase; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (360 aa)
tmkThymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (208 aa)
AMS32272.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (397 aa)
AMS32309.1Chitin deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (328 aa)
AMS32312.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (167 aa)
AMS32313.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (83 aa)
AMS32314.1Molybdenum cofactor biosynthesis protein MoaE; Derived by automated computational analysis using gene prediction method: Protein Homology. (152 aa)
AMS33706.15'-nucleotidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 5'-nucleotidase family. (580 aa)
gmhAPhosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate. (200 aa)
AMS32332.1ADP-ribose pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (181 aa)
aceEPyruvate dehydrogenase; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (895 aa)
AMS32348.13',5'-cyclic-nucleotide phosphodiesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (254 aa)
moaCMolybdenum cofactor biosynthesis protein MoaC; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. (162 aa)
ispDHypothetical protein; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (241 aa)
ispF2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (163 aa)
AMS32423.1Serine--glyoxylate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (407 aa)
AMS32430.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (188 aa)
pyrDDihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (346 aa)
AMS32477.1Molybdopterin molybdenumtransferase; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. (427 aa)
mobAMolybdopterin-guanine dinucleotide biosynthesis protein A; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family. (206 aa)
fdhDFormate dehydrogenase; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family. (269 aa)
moaAHypothetical protein; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (345 aa)
AMS32482.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (173 aa)
purKPhosphoribosylaminoimidazole carboxylase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (381 aa)
purEN5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (166 aa)
AMS32496.1UDP-4-amino-4-deoxy-L-arabinose-oxoglutarate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (319 aa)
AMS32498.14-amino-4-deoxy-L-arabinose transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (124 aa)
surEStationary phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (247 aa)
AMS32508.1Fructose-2,6-bisphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (245 aa)
uppUracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (208 aa)
nadENAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (541 aa)
pdxHHypothetical protein; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). (216 aa)
AMS32547.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (736 aa)
AMS32587.1GTP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (237 aa)
AMS33781.1Nicotinate-nucleotide pyrophosphorylase; Catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NadC/ModD family. (280 aa)
pyrFOrotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (238 aa)
cmkCytidylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (225 aa)
AMS32687.1Hypothetical protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (744 aa)
AMS33799.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (215 aa)
AMS32712.1CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (189 aa)
AMS32724.1L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. (530 aa)
nnrEHypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epi [...] (512 aa)
AMS32746.1Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate. (333 aa)
AMS32748.1Damage-inducible protein CinA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CinA family. (164 aa)
thiLHypothetical protein; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (318 aa)
AMS32839.1ATP synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (477 aa)
nadKHypothetical protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (291 aa)
mogAMolybdenum cofactor biosynthesis protein MogA; Forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (197 aa)
AMS32878.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (430 aa)
AMS32883.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (194 aa)
AMS32891.1Glycerol-3-phosphate dehydrogenase; In Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. (508 aa)
AMS33844.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (185 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (252 aa)
AMS33847.1Serine/threonine protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (279 aa)
AMS33852.1Phosphatidylserine decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). (297 aa)
AMS32924.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (299 aa)
purLPhosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. (1334 aa)
AMS32946.1Deoxyadenosine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (209 aa)
AMS32948.1Phosphoserine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (223 aa)
lpxAUDP-N-acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (256 aa)
fabZ3-hydroxyacyl-ACP dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (150 aa)
lpxDUDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. (341 aa)
dxr1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (408 aa)
AMS32974.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CDS family. (283 aa)
pyrHUridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (244 aa)
AMS32983.1Hypoxanthine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (185 aa)
AMS33011.1citryl-CoA lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HpcH/HpaI aldolase family. (281 aa)
AMS33013.1Aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HpcH/HpaI aldolase family. (329 aa)
thyAThymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (269 aa)
guaBInosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (486 aa)
AMS33887.1Adenylosuccinate lyase; Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (460 aa)
AMS33069.1CDP-diacylglycerol--serine O-phosphatidyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (264 aa)
psdPhosphatidylserine decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). (283 aa)
acsAAMP-dependent synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (661 aa)
AMS33891.1Aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HpcH/HpaI aldolase family. (375 aa)
AMS33892.1acetyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (545 aa)
AMS33098.1Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. (349 aa)
AMS33138.1Inositol monophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the inositol monophosphatase superfamily. (262 aa)
AMS33149.1Hypothetical protein; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (426 aa)
AMS33150.1Quinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (372 aa)
purMPhosphoribosylaminoimidazole synthetase; Catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (346 aa)
purNPhosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (220 aa)
dutDeoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (151 aa)
AMS33196.1Glycerol acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (197 aa)
lpxCUDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. (310 aa)
AMS33213.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (247 aa)
AMS33231.1Nucleotide pyrophosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (115 aa)
AMS33285.1acyl-CoA hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (138 aa)
AMS33301.1Ribulose-phosphate 3-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribulose-phosphate 3-epimerase family. (229 aa)
pdxA4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). (315 aa)
AMS33309.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (250 aa)
AMS33934.1Cation transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (299 aa)
AMS33415.1WbqC-like protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (228 aa)
AMS33419.1Transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (220 aa)
plsYGlycerol-3-phosphate acyltransferase; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. (206 aa)
dxs1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (647 aa)
Your Current Organism:
Betaproteobacteria bacterium UKL132
NCBI taxonomy Id: 1690485
Other names: B. bacterium UKL13-2, Betaproteobacteria bacterium UKL13-2
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