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ribH ribH ribB ribB SHJ46670.1 SHJ46670.1 RibD RibD SHJ46945.1 SHJ46945.1 SHJ45306.1 SHJ45306.1 SHJ45328.1 SHJ45328.1 CoaBC CoaBC lspA lspA SHJ45419.1 SHJ45419.1 SHJ45468.1 SHJ45468.1 SHJ45513.1 SHJ45513.1 nadA nadA SHJ45579.1 SHJ45579.1 SHJ45593.1 SHJ45593.1 SHJ57727.1 SHJ57727.1 nadK nadK SHJ82659.1 SHJ82659.1 SHJ82675.1 SHJ82675.1 SHJ82695.1 SHJ82695.1 SHJ83249.1 SHJ83249.1 FolK FolK panB panB SHJ89735.1 SHJ89735.1 folE2 folE2 SHJ89799.1 SHJ89799.1 SHJ94826.1 SHJ94826.1 SHJ94846.1 SHJ94846.1 SHK06178.1 SHK06178.1 ribB-2 ribB-2 coaD coaD coaX coaX nadD nadD SHK29608.1 SHK29608.1 SHK40949.1 SHK40949.1 SHK40973.1 SHK40973.1 SHK40998.1 SHK40998.1 folE folE SHK49701.1 SHK49701.1 nadE nadE SHK59091.1 SHK59091.1 FolP FolP SHK79389.1 SHK79389.1 nadE-2 nadE-2 ribA ribA panD panD panC panC SHL25480.1 SHL25480.1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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ribH6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (168 aa)
ribB3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. (378 aa)
SHJ46670.1Riboflavin synthase alpha chain. (209 aa)
RibDDiaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (389 aa)
SHJ46945.1(p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (785 aa)
SHJ45306.1Luciferase family oxidoreductase, group 1. (171 aa)
SHJ45328.1Luciferase family oxidoreductase, group 1. (169 aa)
CoaBCPhosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (404 aa)
lspASignal peptidase II Aspartic peptidase. MEROPS family A08; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. (168 aa)
SHJ45419.1FMN adenylyltransferase /riboflavin kinase; Belongs to the ribF family. (331 aa)
SHJ45468.116S rRNA (cytosine967-C5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (419 aa)
SHJ45513.1Mechanosensitive ion channel. (443 aa)
nadAQuinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate; Belongs to the quinolinate synthase A family. Type 1 subfamily. (379 aa)
SHJ45579.1Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Belongs to the NadC/ModD family. (299 aa)
SHJ45593.1L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. (532 aa)
SHJ57727.1Dihydroneopterin aldolase. (178 aa)
nadKNAD+ kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (300 aa)
SHJ82659.1NAD(P) transhydrogenase subunit beta; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. (484 aa)
SHJ82675.1NAD(P) transhydrogenase subunit alpha. (109 aa)
SHJ82695.1NAD(P) transhydrogenase subunit alpha. (380 aa)
SHJ83249.1Dihydroneopterin triphosphate pyrophosphatase. (184 aa)
FolK2-amino-4-hydroxy-6- hydroxymethyldihydropteridinediphosphokinase. (182 aa)
panBKetopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (271 aa)
SHJ89735.1Ketopantoate reductase. (325 aa)
folE2GTP cyclohydrolase I; Converts GTP to 7,8-dihydroneopterin triphosphate. (268 aa)
SHJ89799.1NAD(P) transhydrogenase subunit beta. (309 aa)
SHJ94826.1NAD(P) transhydrogenase subunit beta; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. (464 aa)
SHJ94846.1NAD(P) transhydrogenase subunit alpha; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the AlaDH/PNT family. (524 aa)
SHK06178.1Nicotinamide-nucleotide amidase; Belongs to the CinA family. (166 aa)
ribB-23,4-dihydroxy 2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. (238 aa)
coaDPhosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (171 aa)
coaXType III pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (272 aa)
nadDNicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (261 aa)
SHK29608.1Ketopantoate reductase. (327 aa)
SHK40949.1L-idonate 5-dehydrogenase. (344 aa)
SHK40973.1NAD(P) transhydrogenase subunit beta. (111 aa)
SHK40998.1NAD(P) transhydrogenase subunit beta. (141 aa)
folEGTP cyclohydrolase I. (212 aa)
SHK49701.1GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (747 aa)
nadENAD+ synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (570 aa)
SHK59091.1Ketopantoate reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (311 aa)
FolPDihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (304 aa)
SHK79389.1Amidohydrolase, PncC family; Belongs to the CinA family. (175 aa)
nadE-2NAD+ synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (682 aa)
ribAGTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. (216 aa)
panDL-aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (128 aa)
panCPantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (277 aa)
SHL25480.1Dihydroneopterin aldolase. (131 aa)
Your Current Organism:
Paraburkholderia terricola
NCBI taxonomy Id: 169427
Other names: Burkholderia sp. LMG 20574, Burkholderia terricola, Burkholderia terricola Goris et al. 2003, CCM 7153, CCUG 44527, CIP 107794, DSM 17221, LMG 20594, LMG:20594, P. terricola, Paraburkholderia terricola (Goris et al. 2003) Sawana et al. 2015, strain R-8118
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