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lmo1997 lmo1997 lmo0010 lmo0010 lmo0011 lmo0011 lmo0012 lmo0012 lmo0021 lmo0021 lmo0022 lmo0022 lmo0027 lmo0027 lmo0039 lmo0039 lmo0096 lmo0096 lmo0190 lmo0190 prs prs lmo0221 lmo0221 folK folK lmo0231 lmo0231 lmo0288 lmo0288 lmo0299 lmo0299 lmo0316 lmo0316 lmo0317 lmo0317 lmo0347 lmo0347 lmo0348 lmo0348 lmo0351 lmo0351 lmo0374 lmo0374 lmo0385 lmo0385 lmo0411 lmo0411 prs-2 prs-2 lmo0539 lmo0539 lmo0542 lmo0542 lmo0590 lmo0590 lmo0618 lmo0618 thiD thiD cheA cheA lmo0728 lmo0728 lmo0738 lmo0738 lmo0774 lmo0774 lmo0783 lmo0783 lmo0784 lmo0784 lmo0785 lmo0785 lmo0875 lmo0875 rsbW rsbW lmo0914 lmo0914 lmo0922 lmo0922 lmo0968 lmo0968 lmo1003 lmo1003 lmo1017 lmo1017 lmo1021 lmo1021 lmo1034 lmo1034 lmo1035 lmo1035 lmo1061 lmo1061 lmo1095 lmo1095 lmo1147 lmo1147 AckA2 AckA2 lmo1173 lmo1173 lmo1235 lmo1235 lmo1255 lmo1255 proB proB smbA smbA ribC ribC lmo1339 lmo1339 lmo1370 lmo1370 lisK lisK lmo1436 lmo1436 lmo1457 lmo1457 lmo1464 lmo1464 udk udk lmo1508 lmo1508 lmo1538 lmo1538 lmo1563 lmo1563 pykA pykA pfk pfk ackA ackA lmo1586 lmo1586 argB argB lmo1705 lmo1705 lmo1720 lmo1720 lmo1721 lmo1721 lmo1741 lmo1741 lmo1749 lmo1749 lmo1753 lmo1753 lmo1814 lmo1814 lmo1817 lmo1817 lmo1820 lmo1820 lmo1827 lmo1827 lmo1866 lmo1866 lmo1867 lmo1867 lmo1912 lmo1912 ndk ndk cmk cmk resE resE lmo2002 lmo2002 lmo2011 lmo2011 lmo2095 lmo2095 lmo2174 lmo2174 fruB fruB lmo2341 lmo2341 lmo2373 lmo2373 lmo2374 lmo2374 lmo2421 lmo2421 pgk pgk lmo2483 lmo2483 phoR phoR lmo2544 lmo2544 thrB thrB lmo2557 lmo2557 lmo2582 lmo2582 adk adk lmo2679 lmo2679 lmo2683 lmo2683 lmo2693 lmo2693 lmo2695 lmo2695 lmo2696 lmo2696 lmo2697 lmo2697 lmo2712 lmo2712 lmo2736 lmo2736 lmo2762 lmo2762 lmo2764 lmo2764 lmo2772 lmo2772 lmo2782 lmo2782 bvrB bvrB lmo2832 lmo2832 lmo2849 lmo2849
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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lmo1997Lmo1997 protein; Similar to PTS mannose-specific enzyme IIA component. (138 aa)
lmo0010Lmo0010 protein; Similar to mevalonate kinase. (322 aa)
lmo0011Lmo0011 protein; Similar to mevalonate diphosphate decarboxylase. (323 aa)
lmo0012Lmo0012 protein; Similar to mevalonate kinases. (359 aa)
lmo0021Lmo0021 protein; Similar to PTS system, fructose-specific IIA component. (133 aa)
lmo0022Lmo0022 protein; Similar to PTS system, fructose-specific IIB component. (162 aa)
lmo0027Lmo0027 protein; Similar to PTS system, beta-glucosides specific enzyme IIABC. (634 aa)
lmo0039Similar to carbamate kinase. (313 aa)
lmo0096Lmo0096 protein; Similar to PTS system mannose-specific, factor IIAB. (321 aa)
lmo01904-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (293 aa)
prsPhosphoribosyl pyrophosphate synthetase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (318 aa)
lmo0221Type III pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family. (259 aa)
folKFolK protein; Similar to 7,8-dihydro-6-hydroxymethylpterin pyrophosphokinase. (159 aa)
lmo0231Protein-arginine kinase; Catalyzes the specific phosphorylation of arginine residues in proteins; Belongs to the ATP:guanido phosphotransferase family. (340 aa)
lmo0288Lmo0288 protein; Similar to two-component sensor histidine kinase. (610 aa)
lmo0299Lmo0299 protein; Similar to PTS beta-glucoside-specific enzyme IIB component. (96 aa)
lmo0316Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (269 aa)
lmo0317Lmo0317 protein; Similar to phosphomethylpyrimidine kinase (ThiD). (267 aa)
lmo0347Lmo0347 protein; Similar to dihydroxyacetone kinase. (216 aa)
lmo0348Lmo0348 protein; Similar to dihydroxyacetone kinase. (331 aa)
lmo0351Similar to unknown proteins. (125 aa)
lmo0374Lmo0374 protein; Similar to PTS betaglucoside-specific enzyme IIB component. (100 aa)
lmo03855-dehydro-2-deoxygluconokinase; Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5-dehydro-2- deoxy-D-gluconate (DKGP). (325 aa)
lmo0411Lmo0411 protein; Similar to phosphoenolpyruvate synthase (N-terminal part). (530 aa)
prs-2Putative ribose-phosphate pyrophosphokinase 2; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (311 aa)
lmo0539Similar to tagatose-1,6-diphosphate aldolase; Belongs to the aldolase LacD family. (338 aa)
lmo0542Lmo0542 protein; Similar to PTS system, glucitol/sorbitol-specific enzyme IIA component. (116 aa)
lmo0590Lmo0590 protein; Similar to a fusion of two types of conserved hypothetical proteinconserved hypothetical. (588 aa)
lmo0618Similar to protein kinase. (380 aa)
thiDThiD protein; Highly similar to phosphomethylpyrimidine kinase thiD. (271 aa)
cheATwo-component sensor histidine kinase CheA; Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY (By similarity). (618 aa)
lmo0728FAD synthetase; Catalyzes the adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme. Can also catalyze, with lower efficiency, the adenylation of the toxic riboflavin analogs 8-demethyl-8-aminoriboflavin mononucleotide (AFMN) and roseoflavin mononucleotide (RoFMN) to 8-demethyl-8-aminoriboflavin adenine dinucleotide (AFAD) and roseoflavin adenine dinucleotide (RoFAD), respectively ; Belongs to the RibF family. (246 aa)
lmo0738Lmo0738 protein; Similar to phosphotransferase system (PTS) beta-glucoside-specific enzyme IIABC component. (617 aa)
lmo0774Lmo0774 protein. (309 aa)
lmo0783Lmo0783 protein; Similar to mannose-specific phosphotransferase system (PTS) component IIB. (161 aa)
lmo0784Lmo0784 protein; Similar to mannose-specific phosphotransferase system (PTS) component IIA. (144 aa)
lmo0785Lmo0785 protein; Similar to transcriptional regulator (NifA/NtrC family). (938 aa)
lmo0875Lmo0875 protein; Similar to PTS system, beta-glucoside enzyme IIB component. (111 aa)
rsbWsigma-B activity negative regulator RsbW; Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B). (157 aa)
lmo0914Lmo0914 protein; Similar to PTS system, IIB component. (101 aa)
lmo0922Similar to pantothenate kinase. (306 aa)
lmo0968NAD kinase 1; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (264 aa)
lmo1003Phosphotransferase system enzyme I; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (572 aa)
lmo1017Lmo1017 protein; Similar to phosphotransferase system glucose-specific enzyme IIA. (163 aa)
lmo1021Similar to two-component sensor histidine kinase in particular B. subtilis YvqE protein. (352 aa)
lmo1034Lmo1034 protein; Similar to glycerol kinase. (487 aa)
lmo1035Lmo1035 protein; Similar to phosphotransferase system (PTS) beta-glucoside-specific enzyme IIABC. (618 aa)
lmo1061Histidine kinase; Similar to two-component sensor histidine kinase. (481 aa)
lmo1095Lmo1095 protein; Similar to PTS system, cellobiose-specific IIB component (cel A). (134 aa)
lmo1147Lmo1147 protein; Similar to bifunctional cobalamin biosynthesis protein CopB, (cobinamide kinase; cobinamide phosphatase guanylyltransferase). (185 aa)
AckA2Acetate kinase 2; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (397 aa)
lmo1173Lmo1173 protein; Similar to two-component sensor histidine kinase. (485 aa)
lmo1235Similar to aspartokinase II alpha subunit; Belongs to the aspartokinase family. (404 aa)
lmo1255Lmo1255 protein; Similar to PTS system trehalose specific enzyme IIBC. (494 aa)
proBGamma-glutamyl kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (276 aa)
smbAUridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (242 aa)
ribCBifunctional riboflavin kinase/FMN adenylyltransferase; Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD. Can also catalyze the phosphorylation of the toxic riboflavin analogs 8-demethyl-8- aminoriboflavin (AF) to 8-demethyl-8-aminoriboflavin mononucleotide (AFMN) and roseoflavin (RoF) to roseoflavin mononucleotide (RoFMN), and the adenylation of AFMN to 8-demethyl-8-aminoriboflavin adenine dinucleotide (AFAD) ; Belongs to the RibF family. (314 aa)
lmo1339Lmo1339 protein; Similar to glucose kinase. (322 aa)
lmo1370Probable butyrate kinase; Similar to branched-chain fatty-acid kinase; Belongs to the acetokinase family. (355 aa)
lisKTwo-component sensor histidine kinase. (483 aa)
lmo1436Similar to aspartokinase I (alpha and beta subunits); Belongs to the aspartokinase family. (403 aa)
lmo1457Putative pyruvate, phosphate dikinase regulatory protein 1; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation. (274 aa)
lmo1464Lmo1464 protein; Similar to diacylglycerol kinase. (131 aa)
udkSimilar to Uridine kinase. (209 aa)
lmo1508Lmo1508 protein; Similar to two-component sensor histidine kinase. (479 aa)
lmo1538Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (497 aa)
lmo1563Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (200 aa)
pykAHighly similar to pyruvate kinases. (585 aa)
pfkATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (319 aa)
ackAAcetate kinase 1; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (397 aa)
lmo1586NAD kinase 2; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (267 aa)
argBAcetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (250 aa)
lmo1705Lmo1705 protein; Similar to deoxyguanosine kinase/deoxyadenosine kinase(I) subunit. (214 aa)
lmo1720Lmo1720 protein; Similar to phosphotransferase system (PTS) lichenan-specific enzyme IIB component. (102 aa)
lmo1721Lmo1721 protein; Similar to transcriptional regulator (NifA/NtrC family). (892 aa)
lmo1741Lmo1741 protein; Similar to two-component sensor histidine kinase. (346 aa)
lmo1749Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (157 aa)
lmo1753Lmo1753 protein. (310 aa)
lmo1814Similar to unknown proteins. (552 aa)
lmo1817Lmo1817 protein; Weakly similar to thiamin pyrophosphokinase. (214 aa)
lmo1820Lmo1820 protein; Similar to putative serine/threonine-specific protein kinase. (655 aa)
lmo1827Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (205 aa)
lmo1866Putative pyruvate, phosphate dikinase regulatory protein 2; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation. (270 aa)
lmo1867Similar to pyruvate phosphate dikinase; Belongs to the PEP-utilizing enzyme family. (879 aa)
lmo1912Similar to unknown proteins (hypothetical sensory transduction histidine kinase). (375 aa)
ndkNucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (147 aa)
cmkSimilar to cytidylate kinase. (224 aa)
resEResE protein; Similar to two-component sensor histidine kinase (ResE). (596 aa)
lmo2002Lmo2002 protein; Similar to PTS mannose-specific enzyme IIB component. (155 aa)
lmo2011Histidine kinase; Similar to two-component sensor histidine kinase. (579 aa)
lmo2095Similar to 1-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. (310 aa)
lmo2174Similar to unknown proteins. (357 aa)
fruBFructose-1-phosphate kinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. (307 aa)
lmo2341Lmo2341 protein; Similar to carbohydrate kinases. (372 aa)
lmo2373Lmo2373 protein; Similar to phosphotransferase system (PTS) beta-glucoside-specific enzyme IIB component. (104 aa)
lmo2374Aspartokinase; Similar to aspartate kinase; Belongs to the aspartokinase family. (453 aa)
lmo2421Lmo2421 protein; Similar to two-component sensor histidine kinase. (380 aa)
pgkHighly similar to phosphoglycerate kinase. (396 aa)
lmo2483HPr-P(Ser) kinase/phosphatase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable c [...] (312 aa)
phoRTwo-component sensor histidine kinase. (591 aa)
lmo2544Similar to thymidine kinase. (191 aa)
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (288 aa)
lmo2557Lmo2557 protein. (306 aa)
lmo2582Lmo2582 protein; Similar to two-component sensor histidine kinase. (459 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (215 aa)
lmo2679Lmo2679 protein; Similar to the two components sensor protein kdpD. (896 aa)
lmo2683Lmo2683 protein; Similar to cellobiose phosphotransferase enzyme IIB component. (101 aa)
lmo2693Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (208 aa)
lmo2695Lmo2695 protein; Similar to dihydroxyacetone kinase. (329 aa)
lmo2696Lmo2696 protein; Similar to hypothetical dihydroxyacetone kinase. (198 aa)
lmo2697Lmo2697 protein. (124 aa)
lmo2712Lmo2712 protein; Highly similar to gluconate kinase; Belongs to the FGGY kinase family. (504 aa)
lmo2736Lmo2736 protein; Belongs to the glycerate kinase type-1 family. (377 aa)
lmo2762Lmo2762 protein; Similar to PTS cellobiose-specific enzyme IIB. (100 aa)
lmo2764Beta-glucoside kinase; Catalyzes the ATP-dependent phosphorylation of cellobiose to produce cellobiose-6'-P. May have a dual role of kinase and transcriptional regulator of the cellobiose-PTS operon. Belongs to the ROK (NagC/XylR) family. (294 aa)
lmo2772Lmo2772 protein; Similar to beta-glucoside-specific enzyme IIABC. (617 aa)
lmo2782Lmo2782 protein; Similar to PTS, cellobiose-specific IIB component. (99 aa)
bvrBBeta-glucoside-specific phosphotransferase enzyme II ABC component. (640 aa)
lmo2832Similar to unknown proteins; Belongs to the glycerate kinase type-1 family. (373 aa)
lmo2849Rhamnulokinase; Involved in the catabolism of L-rhamnose (6-deoxy-L-mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1- hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate. Belongs to the rhamnulokinase family. (483 aa)
Your Current Organism:
Listeria monocytogenes
NCBI taxonomy Id: 169963
Other names: L. monocytogenes EGD-e, Listeria monocytogenes ATCC BAA-679, Listeria monocytogenes EGD-e, Listeria monocytogenes EGDe, Listeria monocytogenes str. EGD-e, Listeria monocytogenes strain EGD-e
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