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lmo0881 | Lmo0881 protein. (158 aa) | ||||
hly | Listeriolysin O precursor; Sulfhydryl-activated pore-forming toxin, which is a major virulence factor required for the escape of bacteria from phagosomal vacuoles and entry into the host cytosol. After binding to target membranes, the protein undergoes a major conformation change, leading to its insertion in the host membrane and formation of an oligomeric pore complex. Listeriolysin O activates mitogen-activated protein (MAP) kinase activity in host cells, most likely as a result of the permeabilization of the host cell membrane. Also induces a proteasome- independent degradation of U [...] (529 aa) | ||||
mpl | Zinc metalloproteinase precursor; Probably linked to the pathogenesis of listerial infection; Belongs to the peptidase M4 family. (510 aa) | ||||
actA | Actin-assembly inducing protein precursor; Virulence factor required for host cell microfilament interaction. It induces actin assembly around the bacteria to allow it to move within the cytoplasm. It is involved in the actin polymerization process. It seems to act as a nucleator that induces the reorganization of the actin cytoskeleton. (639 aa) | ||||
plcB | Phospholipase C; Important role in the infectious process. May contribute to efficient lysis of the two-membrane vacuoles that surround the bacteria after direct cell-to-cell spread. (289 aa) | ||||
lmo0206 | Uncharacterized protein Lmo0206. (107 aa) | ||||
lmo0207 | Uncharacterized lipoprotein Lmo0207; Hypothetical lipoprotein. (153 aa) | ||||
lmo0255 | Lmo0255 protein. (167 aa) | ||||
inlG | Internalin G. (490 aa) | ||||
inlH | Internalin H; Contributes to systemic listeriosis in mice by decreasing host IL-6 cytokine production and thus evasion of the host immune response. Does not contribute to invasion of the host intestinal tissue. (548 aa) | ||||
inlE | Internalin E. (499 aa) | ||||
lmo0275 | C-terminal part similar to B. subtilis ComEC protein. (280 aa) | ||||
lmo0285 | Putative lipoprotein; Belongs to the nlpA lipoprotein family. (273 aa) | ||||
lmo0299 | Lmo0299 protein; Similar to PTS beta-glucoside-specific enzyme IIB component. (96 aa) | ||||
lmo0320 | Similar to surface protein (peptidoglycan bound,LPXTG motif). (399 aa) | ||||
lmo0324 | Lmo0324 protein. (159 aa) | ||||
lmo0327 | Lmo0327 protein; Similar to cell surface proteins (LPXTG motif). (1348 aa) | ||||
lmo0331 | Lmo0331 protein; Similar to internalin, putative peptidoglycan bound protein (LPXTG motif). (633 aa) | ||||
lmo0333 | Internalin I; A role in virulence could not be demonstrated. Belongs to the internalin family. (1778 aa) | ||||
lmo0355 | Lmo0355 protein; Similar to Flavocytochrome C Fumarate Reductase chain A; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (506 aa) | ||||
lmo0365 | Lmo0365 protein. (482 aa) | ||||
lmo0366 | Conserved hypothetical protein, putative lipoprotein. (386 aa) | ||||
lmo0374 | Lmo0374 protein; Similar to PTS betaglucoside-specific enzyme IIB component. (100 aa) | ||||
lmo0394 | Lmo0394 protein; Similar to L. monocytogenes extracellular P60 protein. (227 aa) | ||||
lmo0399 | Lmo0399 protein; Similar to fructose-specific phosphotransferase enzyme IIB. (110 aa) | ||||
lmo0409 | Lmo0409 protein; Similar to internalin, peptidoglycan bound protein (LPxTG motif). (821 aa) | ||||
lmo0427 | Lmo0427 protein; Similar to PTS fructose-specific enzyme IIB component. (106 aa) | ||||
inlA | Internalin A; Mediates the entry of L.monocytogenes into host intestinal epithelial cells; transformation with inlA alone allows L.innocua (a non-invasive species) to be taken up by host cells. Binds to human receptor cadherin-1 (E-cadherin, CDH1); the chicken homolog of cadherin-1 but not cadherin- 2 function as receptors. Mouse cadherin-1 is not a receptor, however mutating a single surface-exposed residue (Glu-172 to Pro in mouse) allows cadherin-1 to act as a receptor for InlA ; Belongs to the internalin family. (800 aa) | ||||
inlB | Internalin B; Mediates the entry of L.monocytogenes into normally non- phagocytic mammalian host cells. Its host receptor is hepatocyte growth factor receptor (HGF receptor, a tyrosine kinase, MET) which is tyrosine-phosphorylated in response to InlB. Downstream targets MAPK1/MAPK3 (Erk1/2) and AKT are phosphorylated in response to InlB, which also causes cell colony scattering. Complement component 1 Q subcomponent-binding protein (gC1q-R, C1QBP) has been suggested to also act an InlB receptor, but this is less certain. Stimulation of Tyr-phosphorylation of MET by InlB is potentiated [...] (630 aa) | ||||
lmo0435 | Putative peptidoglycan bound protein (LPXTG motif). (2013 aa) | ||||
lmo0438 | Listeria nuclear targeted protein A; Relieves the repression of host cell immune response genes (interferon-stimulated genes) by blocking the recruitment of host BAHD1 to these genes. May modulate interferon-mediated immune response to control bacterial colonization of the host. (205 aa) | ||||
lmo0460 | Putative membrane associated lipoprotein. (689 aa) | ||||
lmo0462 | Lmo0462 protein. (161 aa) | ||||
lmo0463 | Lmo0463 protein. (101 aa) | ||||
lmo0510 | Lmo0510 protein. (192 aa) | ||||
lmo0514 | Similar to internalin protein, putative peptidoglycan bound protein (LPXTG motif). (605 aa) | ||||
lmo0516 | Lmo0516 protein; Similar to Bacillus anthracis encapsulation protein CapA. (476 aa) | ||||
lmo0517 | Lmo0517 protein; Similar to phosphoglycerate mutase. (271 aa) | ||||
lmo0528 | Hypothetical secreted protein. (498 aa) | ||||
lmo0530 | Lmo0530 protein. (683 aa) | ||||
lmo0541 | Lmo0541 protein; Similar to ABC transporter (binding protein). (306 aa) | ||||
lmo0549 | Similar to internalin protein. (673 aa) | ||||
lmo0550 | Pepdidoglycan bound protein (LPXTG motif). (98 aa) | ||||
lmo0551 | Lmo0551 protein. (280 aa) | ||||
lmo0552 | Lmo0552 protein. (343 aa) | ||||
lmo0576 | Lmo0576 protein; Hypothetical cell wall associated protein. (487 aa) | ||||
iap | P60 extracellular protein, invasion associated protein Iap; This major extracellular protein may be involved in the invasion of non-professional phagocytic cells by Listeria; Belongs to the peptidase C40 family. (482 aa) | ||||
lmo0585 | Putative secreted protein. (237 aa) | ||||
lmo0586 | Lmo0586 protein. (341 aa) | ||||
lmo0587 | Putative secreted protein. (821 aa) | ||||
lmo0610 | Similar to internalin proteins, putative peptidoglycan bound protein (LPXTG motif). (589 aa) | ||||
lmo0617 | Lmo0617 protein. (164 aa) | ||||
lmo0627 | Peptidoglycan bound protein (LPXTG motif) similar to adhesin. (1582 aa) | ||||
lmo0638 | Lmo0638 protein. (209 aa) | ||||
lmo0697 | Similar to flagellar hook protein FlgE. (411 aa) | ||||
lmo0701 | Lmo0701 protein. (467 aa) | ||||
lmo0732 | Putative peptidoglycan bound protein (LPXTG motif). (638 aa) | ||||
lmo0768 | Lmo0768 protein; Similar to sugar ABC transporter, periplasmic sugar-binding protein. (417 aa) | ||||
lmo0791 | Lmo0791 protein. (216 aa) | ||||
lmo0801 | Lmo0801 protein; Similar to internalin, putative peptidoglycan bound protein (LPXTG motif). (646 aa) | ||||
lmo0821 | Lmo0821 protein. (220 aa) | ||||
lmo0835 | Putative peptidoglycan bound protein (LPXTG motif). (334 aa) | ||||
lmo0842 | Putative peptidoglycan bound protein (LPXTG motif). (2044 aa) | ||||
lmo0847 | Lmo0847 protein; Similar to Glutamine ABC transporter (binding and transport protein). (480 aa) | ||||
lmo0859 | Lmo0859 protein; Similar to putative sugar ABC transporter,periplasmic sugar-binding protein. (439 aa) | ||||
lmo0880 | Similar to wall associated protein precursor (LPXTG motif). (462 aa) | ||||
plcA | Phosphatidylinositol-specific phospholipase c; Cleaves glycosylphosphatidylinositol (GPI) and phosphatidylinositol (PI) anchors but not PI phosphates. Important factor in pathogenesis, PI-PLC activity is present only in virulent listeria species. It may participate in the lysis of the phagolysosomal membrane. (317 aa) | ||||
lmo0945 | Lmo0945 protein; Similar to C-terminal part of B. subtilis ComEC protein and to ComEA. (376 aa) | ||||
dltD | DltD protein for D-alanine esterification of lipoteichoic acid and wall teichoic acid. (424 aa) | ||||
gbuC | GbuC protein; Highly similar to glycine betaine ABC transporters (glycine betaine-binding protein). (300 aa) | ||||
lmo1041 | Lmo1041 protein; Similar to molybdate ABC transporter binding protein. (256 aa) | ||||
lmo1068 | Lmo1068 protein. (286 aa) | ||||
lmo1073 | Lmo1073 protein; Similar to metal binding protein (ABC transporter). (299 aa) | ||||
lmo1076 | Lmo1076 protein; Similar to autolysin (EC 3.5.1.28) (N-acetylmuramoyl-L-alanine amidase). (572 aa) | ||||
lmo1095 | Lmo1095 protein; Similar to PTS system, cellobiose-specific IIB component (cel A). (134 aa) | ||||
lmo0019 | Lmo0019 protein. (273 aa) | ||||
lmo0031 | Transcriptional regulator LacI family. (351 aa) | ||||
lmo0047 | Lmo0047 protein. (203 aa) | ||||
lmo0057 | Lmo0057 protein; Similar to B. subtilis YueB protein. (1068 aa) | ||||
lmo0058 | Lmo0058 protein. (171 aa) | ||||
lmo0086 | Lmo0086 protein. (1959 aa) | ||||
lmo0105 | Lmo0105 protein; Highly similar to chitinase B. (756 aa) | ||||
lmo0130 | Cell wall protein Lmo0130; Similar to 5'-nucleotidase, putative peptidoglycan bound protein (LPXTG motif). (784 aa) | ||||
lmo0135 | Lmo0135 protein; Similar to oligopeptide ABC transport system substrate-binding proteins. (524 aa) | ||||
lmo0152 | Lmo0152 protein; Similar to oligopeptide ABC transporter-binding protein. (551 aa) | ||||
lmo0153 | Lmo0153 protein; Similar to a probable high-affinity zinc ABC transporter (Zn(II)-binding lipoprotein); Belongs to the bacterial solute-binding protein 9 family. (313 aa) | ||||
lmo2594 | Lmo2594 protein. (119 aa) | ||||
lmo2591 | Surface protein (GW repeat) similar to N-acetylmuramidase. (508 aa) | ||||
lmo2578 | Lmo2578 protein. (291 aa) | ||||
lmo2576 | Peptidoglycan anchored protein (LPXTG motif). (1530 aa) | ||||
lmo2569 | Lmo2569 protein; Similar to dipeptide ABC transporter (dipeptide-binding protein). (553 aa) | ||||
lmo2568 | Lmo2568 protein. (107 aa) | ||||
ami | Autolysin, amidase. (917 aa) | ||||
lmo2522 | Lmo2522 protein; Similar to hypothetical cell wall binding protein from B. subtilis. (277 aa) | ||||
spl | Peptidoglycan lytic protein P45. (401 aa) | ||||
lmo2504 | Lmo2504 protein; Similar to cell wall binding proteins. (436 aa) | ||||
lmo2499 | Lmo2499 protein; Similar to phosphate ABC transporter (binding protein). (302 aa) | ||||
lmo2470 | Similar to internalin proteins. (388 aa) | ||||
lmo2467 | Lmo2467 protein; Similar to chitinase and chitin binding protein. (478 aa) | ||||
lmo2446 | Lmo2446 protein; Similar to glycosidase; Belongs to the glycosyl hydrolase 31 family. (1091 aa) | ||||
lmo2444 | Lmo2444 protein; Similar to glycosidase. (1310 aa) | ||||
lmo2431 | Lmo2431 protein; Similar to B. subtilis ferrichrome ABC transporter fhuD precursor (ferrichrome-binding protein). (323 aa) | ||||
lmo2417 | Conserved lipoprotein (putative ABC transporter binding protein); Belongs to the nlpA lipoprotein family. (276 aa) | ||||
lmo2416 | Lmo2416 protein. (358 aa) | ||||
lmo2410 | Lmo2410 protein. (183 aa) | ||||
lmo2396 | Similar to internalin proteins, putative peptidoglycan bound protein (LPXTG motif). (940 aa) | ||||
lmo2373 | Lmo2373 protein; Similar to phosphotransferase system (PTS) beta-glucoside-specific enzyme IIB component. (104 aa) | ||||
lmo2349 | Lmo2349 protein; Similar to amino acid ABC transporter (binding protein). (269 aa) | ||||
lmo2331 | Lmo2331 protein; Weakly similar to gp32_Bacteriophage A118 protein. (226 aa) | ||||
arpJ | ArpJ protein; Similar to amino acid ABC transporter, permease protein. (486 aa) | ||||
lmo2219 | Foldase protein PrsA 2; Plays a major role in protein secretion by helping the post- translocational extracellular folding of several secreted proteins. (293 aa) | ||||
lmo2203 | Lmo2203 protein; Similar to N-acetylmuramoyl-L-alanine amidase and to internalin B. (375 aa) | ||||
lmo2196 | Lmo2196 protein; Similar to pheromone ABC transporter (binding protein). (558 aa) | ||||
lmo1115 | Lmo1115 protein; Similar to fibrinogen-binding protein (LPXTG motif). (862 aa) | ||||
lmo1136 | Lmo1136 protein; Similar to internalin, putative peptidoglycan bound protein (LPXTG motif). (539 aa) | ||||
lmo1216 | Lmo1216 protein; Similar to N-acetylmuramoyl-L-alanine amidase (autolysin). (328 aa) | ||||
lmo1264 | Lmo1264 protein. (177 aa) | ||||
lmo1265 | Lmo1265 protein; Weakly similar to oligopeptide ABC transporter AppA (binding protein). (221 aa) | ||||
lmo1289 | Similar to internalin proteins, putative peptidoglycan bound protein (LPXTG motif). (593 aa) | ||||
lmo1290 | Similar to internalin proteins, putative peptidoglycan bound protein (LPXTG motif). (598 aa) | ||||
lmo1333 | Lmo1333 protein; Similar to B. subtilis YqzC protein. (159 aa) | ||||
lmo1340 | Lmo1340 protein; Similar to B. subtilis YqgU protein. (363 aa) | ||||
lmo1379 | Membrane protein insertase YidC 1; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins; Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily. (275 aa) | ||||
tcsA | CD4+ T cell-stimulating antigen, lipoprotein. (357 aa) | ||||
lmo1413 | Putative peptidoglycan bound protein (LPXTG motif). (439 aa) | ||||
opuCC | OpuCC protein; Similar to glycine betaine/carnitine/choline ABC transporter (osmoprotectant-binding protein). (308 aa) | ||||
lmo1444 | Foldase protein PrsA 1; Plays a major role in protein secretion by helping the post- translocational extracellular folding of several secreted proteins. (294 aa) | ||||
lmo1506 | Lmo1506 protein; Similar to transporter. (501 aa) | ||||
lmo1521 | Lmo1521 protein; Similar to N-acetylmuramoyl-L-alanine amidase. (427 aa) | ||||
mreC | Cell shape-determining protein MreC; Involved in formation and maintenance of cell shape. Belongs to the MreC family. (295 aa) | ||||
lmo1585 | Lmo1585 protein; Similar to proteases. (337 aa) | ||||
lmo1649 | Lmo1649 protein. (171 aa) | ||||
lmo1654 | Putative cellsurface protein. (164 aa) | ||||
lmo1656 | Lmo1656 protein. (143 aa) | ||||
lmo1666 | Peptidoglycan linked protein (LPxTG). (1711 aa) | ||||
lmo1671 | Lmo1671 protein; Similar to ABC transporter and adhesion proteins; Belongs to the bacterial solute-binding protein 9 family. (317 aa) | ||||
lmo1720 | Lmo1720 protein; Similar to phosphotransferase system (PTS) lichenan-specific enzyme IIB component. (102 aa) | ||||
lmo1730 | Lmo1730 protein; Similar to sugar ABC transporter binding protein. (414 aa) | ||||
lmo1738 | Lmo1738 protein; Similar to amino acid ABC transporter (binding protein). (271 aa) | ||||
lmo1757 | Lmo1757 protein. (371 aa) | ||||
inlC | Internalin C. (296 aa) | ||||
lmo1800 | Similar to protein-tyrosine phosphatase. (298 aa) | ||||
lmo1847 | Manganese-binding lipoprotein MntA; This protein is probably a component of a manganese permease, a binding protein-dependent, ATP-driven transport system. Belongs to the bacterial solute-binding protein 9 family. (310 aa) | ||||
lmo1883 | Lmo1883 protein; Similar to chitinases; Belongs to the glycosyl hydrolase 18 family. (352 aa) | ||||
lmo1903 | Lmo1903 protein; Similar to thioredoxin. (157 aa) | ||||
lmo1959 | Lmo1959 protein; Similar to ferrichrome binding protein. (313 aa) | ||||
lmo2007 | Lmo2007 protein; Weakly similar to putative sugar-binding lipoproteins. (485 aa) | ||||
lmo2017 | Similar to unknown proteins. (231 aa) | ||||
lmo2026 | Putative peptidoglycan bound protein (LPXTG motif). (626 aa) | ||||
lmo2027 | Putative cell surface protein, similar to internalin proteins. (367 aa) | ||||
lmo2061 | Lmo2061 protein. (205 aa) | ||||
lmo2062 | Lmo2062 protein; Similar to copper export proteins. (541 aa) | ||||
lmo2079 | Lmo2079 protein. (381 aa) | ||||
lmo2080 | Lmo2080 protein. (126 aa) | ||||
lmo2085 | Putative peptidoglycan bound protein (LPXTG motif). (562 aa) | ||||
lmo2119 | Similar to unknown proteins. (452 aa) | ||||
lmo2125 | Maltodextrin-binding protein; Similar to maltose/maltodextrin ABC-transporter (binding protein). (419 aa) | ||||
lmo2156 | Lmo2156 protein. (113 aa) | ||||
lmo2178 | Putative peptidoglycan bound protein (LPXTG motif). (1612 aa) | ||||
lmo2179 | Putative peptidoglycan bound protein (LPXTG motif). (1152 aa) | ||||
lmo2184 | Lmo2184 protein; Similar to ferrichrome ABC transporter (binding protein). (290 aa) | ||||
lmo2185 | Hemin/hemoglobin-binding protein 2; Acts as an extracellular and cell wall-bound hemophore; scavenges host heme and hemoglobin from the environment and also serves as a cell wall receptor for both (Probable). At low hemin (Hn) and hemoglobin (Hb) concentrations adsorbs Hn/Hb and presumably directs it to membrane transporters (Probable). Soluble Hbp2 can probably pass Hn/Hb to cell wall-anchored Hbp2, and both forms can accept Hn/Hb from Hbp1. May be involved in crossing the digestive barrier in infected animals. Binds host hemin (Probable). Binds host hemoglobin with affinity in the na [...] (569 aa) | ||||
lmo2186 | Hemin/hemoglobin-binding protein 1; Binds both host hemin and hemoglobin with affinity in the nanomolar range and presumably directs it to membrane transporters. (207 aa) | ||||
lmo0159 | Putative peptidoglycan bound protein (LPXTG motif). (793 aa) | ||||
lmo0160 | Putative peptidoglycan bound protein (LPXTG motif). (571 aa) | ||||
lmo0171 | Similar to internalin proteins, putative peptidoglycan bound protein (LPXTG motif). (832 aa) | ||||
lmo0175 | Putative peptidoglycan bound protein (LPXTG motif). (415 aa) | ||||
lmo0181 | Lmo0181 protein; Similar to sugar ABC transporter, sugar-binding protein. (418 aa) | ||||
lmo2854 | Membrane protein insertase YidC 2; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins; Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily. (287 aa) | ||||
lmo2839 | Lmo2839 protein; Similar to sugar binding protein (ABC transporter). (430 aa) | ||||
lmo2821 | Internalin J; Involved in several steps of L.monocytogenes infection by both intravenous and oral infection. Probably acts as an adhesion; upon ectopic expression in L.innocula bacteria adhere better to human cell lines. (851 aa) | ||||
lmo2776 | Lmo2776 protein. (131 aa) | ||||
lmo2762 | Lmo2762 protein; Similar to PTS cellobiose-specific enzyme IIB. (100 aa) | ||||
lmo2754 | Lmo2754 protein; Similar to D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5); Belongs to the peptidase S11 family. (445 aa) | ||||
lmo2714 | Peptidoglycan anchored protein (LPXTG motif). (315 aa) | ||||
lmo2713 | Secreted protein with 1 GW repeat. (312 aa) | ||||
lmo2686 | Lmo2686 protein. (177 aa) | ||||
lmo2683 | Lmo2683 protein; Similar to cellobiose phosphotransferase enzyme IIB component. (101 aa) | ||||
lmo2642 | Lmo2642 protein. (443 aa) | ||||
lmo2637 | Conserved lipoprotein. (299 aa) | ||||
lmo2636 | FAD:protein FMN transferase; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein. (360 aa) | ||||
lmo2595 | Similar to unknown proteins. (289 aa) |