STRINGSTRING
metG metG infA infA rpsQ rpsQ rplB rplB rpsL rpsL efp efp rho rho KPK76703.1 KPK76703.1 pnp pnp recG recG KPK76377.1 KPK76377.1 KPK76005.1 KPK76005.1 KPK75785.1 KPK75785.1 KPK74841.1 KPK74841.1 KPK74725.1 KPK74725.1 KPK74664.1 KPK74664.1 KPK74039.1 KPK74039.1 rho-2 rho-2 lysS lysS
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
metGmethionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (669 aa)
infATranslation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. (71 aa)
rpsQHypothetical protein; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (86 aa)
rplB50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (283 aa)
rpsL30S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit. (123 aa)
efpElongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. (188 aa)
rhoTranscription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (446 aa)
KPK76703.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (502 aa)
pnpHypothetical protein; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (705 aa)
recGHypothetical protein; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (702 aa)
KPK76377.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (144 aa)
KPK76005.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily. (426 aa)
KPK75785.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (325 aa)
KPK74841.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (140 aa)
KPK74725.1Derived by automated computational analysis using gene prediction method: Protein Homology. (509 aa)
KPK74664.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (194 aa)
KPK74039.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (106 aa)
rho-2Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (370 aa)
lysSlysyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. (501 aa)
Your Current Organism:
Phycisphaerae bacterium SM2330
NCBI taxonomy Id: 1703411
Other names: P. bacterium SM23_30, Phycisphaerae bacterium SM23_30
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