STRINGSTRING
ALE07542.1 ALE07542.1 ALE04874.1 ALE04874.1 ilvE ilvE sucC sucC sucD sucD ALE04985.1 ALE04985.1 aspA aspA ALE05022.1 ALE05022.1 ALE05048.1 ALE05048.1 purU purU glyA glyA folD folD ALE05071.1 ALE05071.1 ALE05072.1 ALE05072.1 ALE05073.1 ALE05073.1 ALE05074.1 ALE05074.1 eno eno aspA-2 aspA-2 ALE05109.1 ALE05109.1 ALE05133.1 ALE05133.1 prs prs deoC deoC ALE05183.1 ALE05183.1 ALE05192.1 ALE05192.1 ALE07619.1 ALE07619.1 ALE07626.1 ALE07626.1 ALE05244.1 ALE05244.1 ALE07642.1 ALE07642.1 ALE05290.1 ALE05290.1 rbsK rbsK gcvH gcvH gcvP gcvP ALE05453.1 ALE05453.1 ALE05455.1 ALE05455.1 ALE05482.1 ALE05482.1 panB panB ALE05485.1 ALE05485.1 ALE05486.1 ALE05486.1 glsA glsA ALE05531.1 ALE05531.1 lipA lipA ALE05539.1 ALE05539.1 pepA pepA gcvT gcvT acnA acnA ALE05599.1 ALE05599.1 ALE07698.1 ALE07698.1 gltD gltD ALE05619.1 ALE05619.1 aspA-3 aspA-3 ALE07699.1 ALE07699.1 ALE07701.1 ALE07701.1 ALE05677.1 ALE05677.1 ALE05678.1 ALE05678.1 ALE05714.1 ALE05714.1 ALE05715.1 ALE05715.1 ALE05716.1 ALE05716.1 ALE05796.1 ALE05796.1 ALE05797.1 ALE05797.1 ALE05830.1 ALE05830.1 ALE05857.1 ALE05857.1 ALE05889.1 ALE05889.1 ALE05890.1 ALE05890.1 ALE05891.1 ALE05891.1 ALE05927.1 ALE05927.1 pgk pgk tpiA tpiA pgl pgl ALE07763.1 ALE07763.1 zwf zwf tal tal ALE05963.1 ALE05963.1 ALE05965.1 ALE05965.1 leuA leuA ALE07783.1 ALE07783.1 pdxT pdxT ALE06109.1 ALE06109.1 pdxS pdxS ALE06122.1 ALE06122.1 ALE06135.1 ALE06135.1 ALE06170.1 ALE06170.1 ALE07806.1 ALE07806.1 leuA-2 leuA-2 ALE06238.1 ALE06238.1 pepA-2 pepA-2 ALE07833.1 ALE07833.1 tal-2 tal-2 ALE07834.1 ALE07834.1 ALE06319.1 ALE06319.1 ALE06327.1 ALE06327.1 ALE07846.1 ALE07846.1 ALE07848.1 ALE07848.1 ALE06381.1 ALE06381.1 ALE07852.1 ALE07852.1 zwf-2 zwf-2 ALE06416.1 ALE06416.1 ALE06467.1 ALE06467.1 leuD leuD ALE06485.1 ALE06485.1 leuB leuB ilvC ilvC ALE06499.1 ALE06499.1 ALE06500.1 ALE06500.1 ilvD ilvD mqo mqo ALE06609.1 ALE06609.1 ALE07896.1 ALE07896.1 kgd kgd ALE06635.1 ALE06635.1 ALE06670.1 ALE06670.1 ALE07940.1 ALE07940.1 ALE06779.1 ALE06779.1 ALE06780.1 ALE06780.1 ALE06781.1 ALE06781.1 ALE06801.1 ALE06801.1 mdh mdh glyA-2 glyA-2 gcvH-2 gcvH-2 gcvT-2 gcvT-2 gcvP-2 gcvP-2 purU-2 purU-2 ALE07961.1 ALE07961.1 ALE07962.1 ALE07962.1 ALE06908.1 ALE06908.1 ALE06909.1 ALE06909.1 ALE06949.1 ALE06949.1 ALE06950.1 ALE06950.1 ALE06966.1 ALE06966.1 ALE07046.1 ALE07046.1 pfkA pfkA ALE07101.1 ALE07101.1 ALE07136.1 ALE07136.1 ALE07137.1 ALE07137.1 ALE07166.1 ALE07166.1 ALE07167.1 ALE07167.1 ALE07168.1 ALE07168.1 ackA ackA ALE07221.1 ALE07221.1 acsA acsA panD panD ALE08048.1 ALE08048.1 ALE07403.1 ALE07403.1 ALE07420.1 ALE07420.1 ALE07421.1 ALE07421.1 ALE08062.1 ALE08062.1 ALE07437.1 ALE07437.1 ALE07517.1 ALE07517.1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
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experimentally determined
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gene neighborhood
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co-expression
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ALE07542.1Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (485 aa)
ALE04874.1Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (309 aa)
ilvEHypothetical protein; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (324 aa)
sucCsuccinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (389 aa)
sucDsuccinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (300 aa)
ALE04985.1Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. (564 aa)
aspAAspartate ammonia-lyase; Catalyzes the formation of fumarate from aspartate; Derived by automated computational analysis using gene prediction method: Protein Homology. (477 aa)
ALE05022.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (289 aa)
ALE05048.1Isocitrate dehydrogenase; NADP-specific, catalyzes the formation of 2-oxoglutarate from isocitrate or oxalosuccinate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the monomeric-type IDH family. (739 aa)
purUFormyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (289 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (428 aa)
folDMethenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (294 aa)
ALE05071.1Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (266 aa)
ALE05072.1Part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; Derived by automated computational analysis using gene prediction method: Protein Homology. (599 aa)
ALE05073.1Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (155 aa)
ALE05074.1Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (115 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (426 aa)
aspA-2Aspartate ammonia-lyase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (458 aa)
ALE05109.1Fructose 1,6-bisphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (345 aa)
ALE05133.1Succinate-semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (498 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (326 aa)
deoCDeoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (235 aa)
ALE05183.1Flavoprotein disulfide reductase; Catalyzes the reduction of nonspecific electron acceptors such as 2,6-dimethyl-1,4-benzoquinone and 5-hydroxy-1,4-naphthaquinone; does not have lipoamide dehydrogenase activity; Derived by automated computational analysis using gene prediction method: Protein Homology. (475 aa)
ALE05192.1Catalyzes the oxidation of acetaldehyde, benzaldehyde, propionaldehyde and other aldehydes; Derived by automated computational analysis using gene prediction method: Protein Homology. (507 aa)
ALE07619.1Polyphosphate glucokinase; Catalyzes the phosphorylation of glucose using polyphosphate or ATP as the phosphoryl donor; Derived by automated computational analysis using gene prediction method: Protein Homology. (263 aa)
ALE07626.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (299 aa)
ALE05244.1Fructose-bisphosphate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (283 aa)
ALE07642.1Pyruvate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (364 aa)
ALE05290.12-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (336 aa)
rbsKRibokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (289 aa)
gcvHGlycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (128 aa)
gcvPGlycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (964 aa)
ALE05453.1Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1132 aa)
ALE05455.1Glucokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (356 aa)
ALE05482.1Polyphosphate glucokinase; Catalyzes the phosphorylation of glucose using polyphosphate or ATP as the phosphoryl donor; Derived by automated computational analysis using gene prediction method: Protein Homology. (264 aa)
panB3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (299 aa)
ALE05485.1Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family. (446 aa)
ALE05486.1Glutamine-synthetase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB [...] (1013 aa)
glsAGlutaminase; Catalyzes the formation of glutamate from glutamine; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutaminase family. (303 aa)
ALE05531.1Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (474 aa)
lipALipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (338 aa)
ALE05539.1Dihydrolipoamide dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (460 aa)
pepAAminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. (507 aa)
gcvTGlycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine. (377 aa)
acnAAconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (941 aa)
ALE05599.1Ribulose phosphate epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribulose-phosphate 3-epimerase family. (227 aa)
ALE07698.1Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1551 aa)
gltDGlutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; Derived by automated computational analysis using gene prediction method: Protein Homology. (485 aa)
ALE05619.1Pyruvate kinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology. (494 aa)
aspA-3Aspartate ammonia-lyase; Catalyzes the formation of fumarate from aspartate; Derived by automated computational analysis using gene prediction method: Protein Homology. (470 aa)
ALE07699.1Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (470 aa)
ALE07701.1Phosphoketolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (814 aa)
ALE05677.1Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (456 aa)
ALE05678.1Glycine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (520 aa)
ALE05714.1Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (344 aa)
ALE05715.1Transcriptional regulator; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation. (271 aa)
ALE05716.1Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (797 aa)
ALE05796.1Malate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the malate synthase family. (535 aa)
ALE05797.1Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (468 aa)
ALE05830.1Pyruvate dehydrogenase; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (913 aa)
ALE05857.1Catalyzes the reduction of mycothione or glutathione to mycothione or glutathione disulfide; Derived by automated computational analysis using gene prediction method: Protein Homology. (466 aa)
ALE05889.1Methylmalonate-semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (494 aa)
ALE05890.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (453 aa)
ALE05891.1Phenylacetaldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (479 aa)
ALE05927.1Glyceraldehyde-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (336 aa)
pgkPhosphoglycerate kinase; Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phosphoglycerate kinase family. (412 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (271 aa)
pgl6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (268 aa)
ALE07763.1OpcA protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (313 aa)
zwfGlucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (514 aa)
talTransaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. (373 aa)
ALE05963.1Lipoate--protein ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (353 aa)
ALE05965.1Aminopeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (882 aa)
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (580 aa)
ALE07783.1Peptidase M13; Derived by automated computational analysis using gene prediction method: Protein Homology. (654 aa)
pdxTGlutamine amidotransferase; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (226 aa)
ALE06109.1Asparagine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (894 aa)
pdxSPyridoxal biosynthesis lyase PdxS; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (300 aa)
ALE06122.1Lipoate--protein ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (242 aa)
ALE06135.1Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (487 aa)
ALE06170.1Catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity; Derived by automated computational analysis using gene prediction method: Protein Homology. (157 aa)
ALE07806.1Aminopeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (852 aa)
leuA-22-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (609 aa)
ALE06238.1Thiamine pyrophosphate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. (597 aa)
pepA-2Leucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. (497 aa)
ALE07833.1Transketolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the transketolase family. (714 aa)
tal-2Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. (388 aa)
ALE07834.13-hexulose-6-phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (207 aa)
ALE06319.13-hexulose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (199 aa)
ALE06327.1Glyceraldehyde-3-phosphate dehydrogenase; Catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; involved in growth under gluconeogenic conditions and in glycolytic activity at high ATP concentrations in Corynebacterium; NAD and NADP dependent; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (485 aa)
ALE07846.1Glutamate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the group II decarboxylase family. (442 aa)
ALE07848.1Glyceraldehyde-3-phosphate dehydrogenase; Catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; involved in growth under gluconeogenic conditions and in glycolytic activity at high ATP concentrations in Corynebacterium; NAD and NADP dependent; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (480 aa)
ALE06381.16-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (478 aa)
ALE07852.1Pyruvate dehydrogenase; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (913 aa)
zwf-2Glucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (466 aa)
ALE06416.1Transcriptional regulator; Indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; Derived by automated computational analysis using gene prediction method: Protein Homology. (112 aa)
ALE06467.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (462 aa)
leuDIsopropylmalate isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (199 aa)
ALE06485.1Catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; Derived by automated computational analysis using gene prediction method: Protein Homology. (370 aa)
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily. (350 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (341 aa)
ALE06499.1Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (170 aa)
ALE06500.1Acetolactate synthase large subunit; catalyzes the formation of 2-acetolactate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology. (629 aa)
ilvDDihydroxy-acid dehydratase; Catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. (582 aa)
mqoMalate:quinone oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (499 aa)
ALE06609.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (183 aa)
ALE07896.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (163 aa)
kgdAlpha-ketoglutarate decarboxylase; Kgd; produces succinic semialdehyde; part of alternative pathway from alpha-ketoglutarate to succinate; essential for normal growth; Derived by automated computational analysis using gene prediction method: Protein Homology. (1273 aa)
ALE06635.1AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (555 aa)
ALE06670.1Glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1626 aa)
ALE07940.1FMN-dependent dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (397 aa)
ALE06779.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (246 aa)
ALE06780.1Metal-dependent phosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (282 aa)
ALE06781.1Xaa-Pro aminopeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase M24B family. (516 aa)
ALE06801.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family. (427 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (331 aa)
glyA-2Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (438 aa)
gcvH-2Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (127 aa)
gcvT-2Glycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine. (373 aa)
gcvP-2Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (963 aa)
purU-2Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (286 aa)
ALE07961.1Gamma-aminobutyraldehyde dehydrogenase; Catalyzes the formation of 4-aminobutanoate from 4-aminobutanal; involved in putrescine degradation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (477 aa)
ALE07962.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (351 aa)
ALE06908.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (287 aa)
ALE06909.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (395 aa)
ALE06949.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (60 aa)
ALE06950.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (159 aa)
ALE06966.1Carboxylate--amine ligase; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily. (380 aa)
ALE07046.1Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (410 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (341 aa)
ALE07101.11-pyrroline-5-carboxylate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (1150 aa)
ALE07136.14-aminobutyrate aminotransferase; Catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (454 aa)
ALE07137.1Phenylacetaldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (476 aa)
ALE07166.1Branched-chain alpha-keto acid dehydrogenase subunit E2; Derived by automated computational analysis using gene prediction method: Protein Homology. (522 aa)
ALE07167.12-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (362 aa)
ALE07168.1Pyruvate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (386 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (380 aa)
ALE07221.1Converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (446 aa)
acsAacetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (658 aa)
panDAspartate 1-decarboxylase subunit alpha; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (132 aa)
ALE08048.1Pyridine nucleotide-disulfide oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (449 aa)
ALE07403.1Aspartate aminotransferase; Catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. (402 aa)
ALE07420.1Branched-chain alpha-keto acid dehydrogenase subunit E2; Derived by automated computational analysis using gene prediction method: Protein Homology. (459 aa)
ALE07421.12-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (324 aa)
ALE08062.1Pyruvate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (390 aa)
ALE07437.1Pyruvate dehydrogenase; Catalyzes the formation of acetate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. (582 aa)
ALE07517.16-phosphogluconate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (295 aa)
Your Current Organism:
Arthrobacter sp. ERGS101
NCBI taxonomy Id: 1704044
Other names: A. sp. ERGS1:01, Arthrobacter sp. ERGS1:01
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