STRINGSTRING
ilvE ilvE ALE04913.1 ALE04913.1 serC serC ALE04974.1 ALE04974.1 ALE07566.1 ALE07566.1 ALE04985.1 ALE04985.1 glyA glyA folD folD ALE05076.1 ALE05076.1 ALE05095.1 ALE05095.1 ALE05180.1 ALE05180.1 ALE05205.1 ALE05205.1 kbl kbl metXA metXA ALE05293.1 ALE05293.1 dapB dapB dapF dapF hisC hisC hisB hisB hisH hisH hisA hisA ALE05383.1 ALE05383.1 ALE05384.1 ALE05384.1 argC argC argJ argJ argB argB argD argD ALE05387.1 ALE05387.1 argR argR argG argG argH argH ALE05438.1 ALE05438.1 ALE05442.1 ALE05442.1 ALE05458.1 ALE05458.1 hisD hisD panB panB ALE05485.1 ALE05485.1 ALE05531.1 ALE05531.1 lipA lipA hisE hisE hisG hisG hisF hisF hisI hisI trpE trpE trpC trpC trpB trpB trpA trpA ALE07698.1 ALE07698.1 gltD gltD ALE05625.1 ALE05625.1 ALE05658.1 ALE05658.1 ALE05722.1 ALE05722.1 ALE05729.1 ALE05729.1 ALE05751.1 ALE05751.1 ALE05778.1 ALE05778.1 ALE05812.1 ALE05812.1 ALE07740.1 ALE07740.1 ALE05832.1 ALE05832.1 ALE05867.1 ALE05867.1 ALE05890.1 ALE05890.1 ALE07754.1 ALE07754.1 ALE07756.1 ALE07756.1 ALE05958.1 ALE05958.1 ALE05975.1 ALE05975.1 ALE05983.1 ALE05983.1 ALE05985.1 ALE05985.1 ALE06014.1 ALE06014.1 ALE06022.1 ALE06022.1 ALE06027.1 ALE06027.1 ALE07779.1 ALE07779.1 trpD trpD ALE06044.1 ALE06044.1 leuA leuA ALE06072.1 ALE06072.1 carB carB carA carA ALE06083.1 ALE06083.1 aroB aroB aroK aroK aroC aroC ALE06093.1 ALE06093.1 ALE06109.1 ALE06109.1 metE metE ALE06138.1 ALE06138.1 proB proB ALE06157.1 ALE06157.1 ALE06163.1 ALE06163.1 leuA-2 leuA-2 ALE06198.1 ALE06198.1 ALE06238.1 ALE06238.1 ALE06377.1 ALE06377.1 ALE06378.1 ALE06378.1 ALE06393.1 ALE06393.1 fabH fabH acpP acpP ALE06396.1 ALE06396.1 ALE07861.1 ALE07861.1 leuD leuD ALE06485.1 ALE06485.1 leuB leuB ALE06497.1 ALE06497.1 ilvC ilvC ALE06499.1 ALE06499.1 ALE06500.1 ALE06500.1 ilvD ilvD ALE07880.1 ALE07880.1 nadA nadA thrB thrB ALE06575.1 ALE06575.1 ALE06576.1 ALE06576.1 lysA lysA ALE06598.1 ALE06598.1 aroA aroA ALE06631.1 ALE06631.1 ALE06683.1 ALE06683.1 ALE07916.1 ALE07916.1 ALE07931.1 ALE07931.1 ALE06735.1 ALE06735.1 ALE06795.1 ALE06795.1 dapD dapD ALE06815.1 ALE06815.1 ALE06831.1 ALE06831.1 ALE06835.1 ALE06835.1 bioD bioD ALE07955.1 ALE07955.1 ALE06837.1 ALE06837.1 bioB bioB ALE06859.1 ALE06859.1 glyA-2 glyA-2 ALE06882.1 ALE06882.1 ALE06884.1 ALE06884.1 trpF trpF ALE06920.1 ALE06920.1 ALE06965.1 ALE06965.1 acpS acpS ALE07997.1 ALE07997.1 ALE07057.1 ALE07057.1 ALE07063.1 ALE07063.1 ALE07064.1 ALE07064.1 ALE07070.1 ALE07070.1 ALE07097.1 ALE07097.1 ALE07098.1 ALE07098.1 ALE07197.1 ALE07197.1 ALE07218.1 ALE07218.1 ALE07220.1 ALE07220.1 proC proC aroQ aroQ ALE07323.1 ALE07323.1 metZ metZ panD panD ALE07370.1 ALE07370.1 ALE07384.1 ALE07384.1 ALE07437.1 ALE07437.1 ALE08066.1 ALE08066.1 ALE07446.1 ALE07446.1 ALE07448.1 ALE07448.1 ALE07529.1 ALE07529.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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ilvEHypothetical protein; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (324 aa)
ALE04913.1Allantoate amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (418 aa)
serCPhosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (375 aa)
ALE04974.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (275 aa)
ALE07566.1Agmatinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the arginase family. (364 aa)
ALE04985.1Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. (564 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (428 aa)
folDMethenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (294 aa)
ALE05076.1N-acyl-L-amino acid amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (401 aa)
ALE05095.1Threonine dehydratase; Catalyzes the formation of 2-oxobutanoate from L-threonine; Derived by automated computational analysis using gene prediction method: Protein Homology. (412 aa)
ALE05180.1Uroporphyrinogen III synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (379 aa)
ALE05205.1methylmalonyl-CoA carboxyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (527 aa)
kbl2-amino-3-ketobutyrate CoA ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. (403 aa)
metXAHomoserine acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. (371 aa)
ALE05293.1methylcrotonoyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (535 aa)
dapB4-hydroxy-tetrahydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (252 aa)
dapFDiaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (311 aa)
hisCAspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (365 aa)
hisBImidazoleglycerol-phosphate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (208 aa)
hisHGlutamine amidotransferase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (226 aa)
hisAPhosphoribosyl isomerase; Catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide and the formation of 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate from N-(5-phospho-beta-D-ribosyl)anthranilate; involved in histidine and tryptophan biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (246 aa)
ALE05383.1Amino acid adenylation protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (1310 aa)
ALE05384.1NADPH--quinone reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (324 aa)
argCN-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (348 aa)
argJN-acetylglutamate synthase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (389 aa)
argBAcetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (299 aa)
argDAcetylornithine aminotransferase; Catalyzes the formation of N-acetyl-l-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (422 aa)
ALE05387.1Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (323 aa)
argRArginine repressor; Regulates arginine biosynthesis genes. (178 aa)
argGArgininosuccinate synthase; Catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (401 aa)
argHArgininosuccinate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (471 aa)
ALE05438.1Prephenate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (367 aa)
ALE05442.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (277 aa)
ALE05458.1Phospho-2-dehydro-3-deoxyheptonate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II DAHP synthase family. (462 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (442 aa)
panB3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (299 aa)
ALE05485.1Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family. (446 aa)
ALE05531.1Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (474 aa)
lipALipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (338 aa)
hisEphosphoribosyl-ATP pyrophosphatase; Catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribolsyl)-ATP in histidine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (87 aa)
hisGATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (281 aa)
hisFImidazole glycerol phosphate synthase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (256 aa)
hisIphosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. (140 aa)
trpEAnthranilate synthase; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia. (522 aa)
trpCIndole-3-glycerol phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpC family. (272 aa)
trpBTryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (445 aa)
trpATryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (281 aa)
ALE07698.1Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1551 aa)
gltDGlutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; Derived by automated computational analysis using gene prediction method: Protein Homology. (485 aa)
ALE05625.1Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (350 aa)
ALE05658.1Cupin; Derived by automated computational analysis using gene prediction method: Protein Homology. (377 aa)
ALE05722.1Deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (206 aa)
ALE05729.12-hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (339 aa)
ALE05751.1NADPH:quinone reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (300 aa)
ALE05778.1Hypothetical protein; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. (256 aa)
ALE05812.1NADPH:quinone reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (310 aa)
ALE07740.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (163 aa)
ALE05832.1Asp/Glu/hydantoin racemase; Derived by automated computational analysis using gene prediction method: Protein Homology. (242 aa)
ALE05867.1Threonine dehydratase; Catalyzes the formation of 2-oxobutanoate from L-threonine; Derived by automated computational analysis using gene prediction method: Protein Homology. (310 aa)
ALE05890.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (453 aa)
ALE07754.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (467 aa)
ALE07756.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (403 aa)
ALE05958.1Phosphoserine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (298 aa)
ALE05975.1Dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (310 aa)
ALE05983.12,5-diketo-D-gluconic acid reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (285 aa)
ALE05985.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (434 aa)
ALE06014.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (220 aa)
ALE06022.1Deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (178 aa)
ALE06027.1Deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (192 aa)
ALE07779.1Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (138 aa)
trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (354 aa)
ALE06044.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (474 aa)
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (580 aa)
ALE06072.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (277 aa)
carBCarbamoyl phosphate synthase large subunit; Four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; Derived by automated computational analysis using gene prediction method: Protein Homology. (1114 aa)
carACarbamoyl phosphate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarA family. (402 aa)
ALE06083.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (170 aa)
aroB3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (363 aa)
aroKShikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (192 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (399 aa)
ALE06093.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (298 aa)
ALE06109.1Asparagine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (894 aa)
metE5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (771 aa)
ALE06138.15,10-methylenetetrahydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the methylenetetrahydrofolate reductase family. (322 aa)
proBGamma-glutamyl kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (379 aa)
ALE06157.1Dihydrofolate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the folylpolyglutamate synthase family. (460 aa)
ALE06163.1UDP-glucose 6-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (446 aa)
leuA-22-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (609 aa)
ALE06198.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (329 aa)
ALE06238.1Thiamine pyrophosphate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. (597 aa)
ALE06377.1Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cysteine synthase/cystathionine beta- synthase family. (311 aa)
ALE06378.1Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (195 aa)
ALE06393.1ACP S-malonyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (314 aa)
fabH3-oxoacyl-ACP synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (354 aa)
acpPAcyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. (81 aa)
ALE06396.13-oxoacyl-ACP synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (419 aa)
ALE07861.13-oxoacyl-ACP synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (351 aa)
leuDIsopropylmalate isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (199 aa)
ALE06485.1Catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; Derived by automated computational analysis using gene prediction method: Protein Homology. (370 aa)
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily. (350 aa)
ALE06497.13-phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (531 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (341 aa)
ALE06499.1Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (170 aa)
ALE06500.1Acetolactate synthase large subunit; catalyzes the formation of 2-acetolactate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology. (629 aa)
ilvDDihydroxy-acid dehydratase; Catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. (582 aa)
ALE07880.1Acetylornithine deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (431 aa)
nadAQuinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (450 aa)
thrBSerine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (333 aa)
ALE06575.1Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (367 aa)
ALE06576.1Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (449 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (487 aa)
ALE06598.1Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (360 aa)
aroA3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (447 aa)
ALE06631.1Histidinol phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (270 aa)
ALE06683.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (368 aa)
ALE07916.1Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (318 aa)
ALE07931.1Hypothetical protein; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (295 aa)
ALE06735.1Molybdopterin biosynthesis-like protein MoeZ; The proteins in this cluster have high sequence similarity to MoeB and are possibly involved in the synthesis of molybdopterin, but there has been no biochemical or physiological characterization. There is also no genetic linkage to other molybdopterin cofactor synthesis proteins. These proteins are similar to a Pseudomonas stutzeri protein which is essential to pyridine-2,6-bis(thiocarboxylic acid) synthesis that possibly activates a substrate by adenylation; Derived by automated computational analysis using gene prediction method: Protein [...] (398 aa)
ALE06795.1Succinyl-diaminopimelate desuccinylase; Catalyzes the formation of succinate and diaminoheptanedioate from succinyldiaminoheptanedioate; Derived by automated computational analysis using gene prediction method: Protein Homology. (366 aa)
dapD2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA. (335 aa)
ALE06815.1DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (214 aa)
ALE06831.1Cystathionine gamma-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (390 aa)
ALE06835.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (281 aa)
bioDDethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (231 aa)
ALE07955.18-amino-7-oxononanoate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (374 aa)
ALE06837.1Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (457 aa)
bioBBiotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (360 aa)
ALE06859.1Amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (392 aa)
glyA-2Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (438 aa)
ALE06882.1FAD-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (430 aa)
ALE06884.1Agmatinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the arginase family. (350 aa)
trpFPhosphoribosylanthranilate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpF family. (204 aa)
ALE06920.1NADPH:quinone oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (325 aa)
ALE06965.1Shikimate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (263 aa)
acpSDNA-binding protein; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (115 aa)
ALE07997.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (180 aa)
ALE07057.12-hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (339 aa)
ALE07063.1Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (194 aa)
ALE07064.1Aspartate-semialdehyde dehydrogenase; Catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartate-semialdehyde dehydrogenase family. (378 aa)
ALE07070.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0336 family. (149 aa)
ALE07097.1Cystathionine gamma-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (386 aa)
ALE07098.1Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (458 aa)
ALE07197.1Deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (188 aa)
ALE07218.1Haloacid dehalogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (270 aa)
ALE07220.1Phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (375 aa)
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (278 aa)
aroQ3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (153 aa)
ALE07323.14-amino-4-deoxychorismate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (305 aa)
metZO-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. (403 aa)
panDAspartate 1-decarboxylase subunit alpha; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (132 aa)
ALE07370.1Deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (184 aa)
ALE07384.1GCN5 family acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (159 aa)
ALE07437.1Pyruvate dehydrogenase; Catalyzes the formation of acetate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. (582 aa)
ALE08066.1Thiamine biosynthesis protein ThiS; Derived by automated computational analysis using gene prediction method: Protein Homology. (93 aa)
ALE07446.1Deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (214 aa)
ALE07448.1Deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (194 aa)
ALE07529.1Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamate synthase family. (537 aa)
Your Current Organism:
Arthrobacter sp. ERGS101
NCBI taxonomy Id: 1704044
Other names: A. sp. ERGS1:01, Arthrobacter sp. ERGS1:01
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