STRINGSTRING
rplT rplT ctc ctc adk adk ALJ57003.1 ALJ57003.1 hemA hemA ALJ57014.1 ALJ57014.1 speA speA pheA_1 pheA_1 rpsR rpsR yocK yocK ctaA ctaA nadD nadD ALJ56255.1 ALJ56255.1 mcsB mcsB iscS iscS ybeY ybeY lrtA lrtA acoA_1 acoA_1 pdhB pdhB ribF ribF nrnA nrnA pdg pdg ychF ychF hup hup ispE ispE priA priA ALJ56390.1 ALJ56390.1 rpmE rpmE topB topB ALJ56414.1 ALJ56414.1 ALJ56428.1 ALJ56428.1 ALJ56433.1 ALJ56433.1 rpsI rpsI rplM rplM rpmI rpmI rplU rplU rpsB rpsB rplL rplL rplJ rplJ rplA rplA rplK rplK argA argA ftsZ ftsZ ALJ56550.1 ALJ56550.1 recR recR bsdB bsdB rpsP rpsP rpsT rpsT rpsN2 rpsN2 truA truA rpmH rpmH ulaG ulaG dnaG dnaG ALJ56620.1 ALJ56620.1 argC argC argB argB rpsL rpsL rpsG rpsG rpsJ rpsJ rplC rplC rplD rplD rplW rplW rplB rplB rpsS rpsS rplV rplV rpsC rpsC rplP rplP rpmC rpmC rpsQ rpsQ rplN rplN rplX rplX rplE rplE rpsH rpsH rplF rplF rplR rplR rpsE rpsE rplO rplO rpsM rpsM rpsK rpsK rpsD rpsD lysA lysA rplS rplS leuA_1 leuA_1 sufD sufD sufB sufB tadA tadA rpsO rpsO ALJ56795.1 ALJ56795.1 rapA rapA phnP phnP folK folK crtB crtB rpsA rpsA ogt ogt rpmB rpmB rnjA rnjA bfmBAB bfmBAB acoA_2 acoA_2 ALJ56921.1 ALJ56921.1 ALJ56935.1 ALJ56935.1 pckG pckG leuA_2 leuA_2 rplQ rplQ dnaC dnaC rpsF rpsF
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
rplT50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. (126 aa)
ctcGeneral stress protein CTC; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily. (219 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (238 aa)
ALJ57003.1Ribonuclease. (456 aa)
hemAGlutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (345 aa)
ALJ57014.1HNH endonuclease. (207 aa)
speABiosynthetic arginine decarboxylase; Catalyzes the biosynthesis of agmatine from arginine. (640 aa)
pheA_1Prephenate dehydratase. (298 aa)
rpsR30S ribosomal protein S18; Belongs to the bacterial ribosomal protein bS18 family. (61 aa)
yocKGeneral stress protein 16O. (199 aa)
ctaAHeme A synthase. (332 aa)
nadDNicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (198 aa)
ALJ56255.1Rubrerythrin. (313 aa)
mcsBPutative ATP:guanido phosphotransferase; Catalyzes the specific phosphorylation of arginine residues in proteins; Belongs to the ATP:guanido phosphotransferase family. (364 aa)
iscSCysteine desulfurase. (389 aa)
ybeYEndoribonuclease YbeY; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. (192 aa)
lrtALight-repressed protein A. (120 aa)
acoA_1Acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (397 aa)
pdhBPyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (324 aa)
ribFRiboflavin biosynthesis protein RibF; Belongs to the ribF family. (307 aa)
nrnABifunctional oligoribonuclease and PAP phosphatase NrnA. (336 aa)
pdgUltraviolet N-glycosylase/AP lyase; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (248 aa)
ychFRibosome-binding ATPase YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. (372 aa)
hupDNA-binding protein HU; Belongs to the bacterial histone-like protein family. (110 aa)
ispE4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (287 aa)
priAPrimosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (747 aa)
ALJ56390.1Hypothetical protein. (123 aa)
rpmE50S ribosomal protein L31; Belongs to the bacterial ribosomal protein bL31 family. (124 aa)
topBDNA topoisomerase 3. (811 aa)
ALJ56414.1RNA recognition motif protein. (101 aa)
ALJ56428.1ATPase family associated with various cellular activities (AAA). (328 aa)
ALJ56433.1Hypothetical protein. (589 aa)
rpsI30S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family. (131 aa)
rplM50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (140 aa)
rpmI50S ribosomal protein L35; Belongs to the bacterial ribosomal protein bL35 family. (67 aa)
rplU50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. (161 aa)
rpsB30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. (250 aa)
rplL50S ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. (126 aa)
rplJ50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (173 aa)
rplA50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. (233 aa)
rplK50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. (142 aa)
argAAmino-acid acetyltransferase; Belongs to the acetyltransferase family. (427 aa)
ftsZCell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (446 aa)
ALJ56550.1Hypothetical protein. (493 aa)
recRRecombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. (204 aa)
bsdBPhenolic acid decarboxylase subunit B; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (194 aa)
rpsP30S ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family. (89 aa)
rpsT30S ribosomal protein S20; Binds directly to 16S ribosomal RNA. (84 aa)
rpsN2Alternate 30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family. (116 aa)
truAtRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (254 aa)
rpmH50S ribosomal protein L34; Belongs to the bacterial ribosomal protein bL34 family. (57 aa)
ulaGPutative L-ascorbate-6-phosphate lactonase UlaG. (288 aa)
dnaGDNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (606 aa)
ALJ56620.1Squalene/phytoene synthase. (304 aa)
argCN-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (345 aa)
argBAcetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (292 aa)
rpsL30S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit. (136 aa)
rpsG30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. (157 aa)
rpsJ30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (105 aa)
rplC50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (218 aa)
rplD50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. (205 aa)
rplW50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. (96 aa)
rplB50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (279 aa)
rpsS30S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (92 aa)
rplV50S ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. (145 aa)
rpsC30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. (215 aa)
rplP50S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. (146 aa)
rpmC50S ribosomal protein L29; Belongs to the universal ribosomal protein uL29 family. (77 aa)
rpsQ30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (99 aa)
rplN50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (120 aa)
rplX50S ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit. (102 aa)
rplE50S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (182 aa)
rpsH30S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (132 aa)
rplF50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (181 aa)
rplR50S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (116 aa)
rpsE30S ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family. (190 aa)
rplO50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (181 aa)
rpsM30S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family. (131 aa)
rpsK30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. (171 aa)
rpsD30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (220 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (440 aa)
rplS50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. (115 aa)
leuA_12-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (530 aa)
sufDFeS cluster assembly protein SufD. (431 aa)
sufBFeS cluster assembly protein SufB. (489 aa)
tadAtRNA-specific adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. (181 aa)
rpsO30S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome. (94 aa)
ALJ56795.1Hypothetical protein. (139 aa)
rapARNA polymerase-associated protein RapA. (793 aa)
phnPPhosphoribosyl 1,2-cyclic phosphodiesterase. (257 aa)
folK2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. (180 aa)
crtBAll-trans-phytoene synthase. (274 aa)
rpsA30S ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. (565 aa)
ogtMethylated-DNA--protein-cysteine methyltransferase, constitutive. (170 aa)
rpmB50S ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family. (88 aa)
rnjARibonuclease J 1. (214 aa)
bfmBAB2-oxoisovalerate dehydrogenase subunit beta. (321 aa)
acoA_2Acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit alpha. (341 aa)
ALJ56921.1Hypothetical protein. (205 aa)
ALJ56935.1Hypothetical protein. (276 aa)
pckGPhosphoenolpyruvate carboxykinase [GTP]; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (619 aa)
leuA_22-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (553 aa)
rplQ50S ribosomal protein L17. (131 aa)
dnaCReplicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (460 aa)
rpsF30S ribosomal protein S6. (104 aa)
Your Current Organism:
Xiphinematobacter sp. Idaho
NCBI taxonomy Id: 1704307
Other names: C. Xiphinematobacter sp. Idaho Grape, Candidatus Xiphinematobacter sp. Idaho Grape
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