STRINGSTRING
FBH1 FBH1 RAD52 RAD52 RPA1 RPA1 RMI2 RMI2 FANCM FANCM TOP3A TOP3A RMI1 RMI1 MEIOB MEIOB RECQL5 RECQL5 RPA4 RPA4 TOP3B TOP3B WRN WRN BLM BLM RPA2 RPA2 RPA3 RPA3 TDRD3 TDRD3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FBH1F-box DNA helicase 1 isoform X1. (1040 aa)
RAD52DNA repair protein RAD52 homolog isoform X1. (419 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (617 aa)
RMI2recQ-mediated genome instability protein 2. (149 aa)
FANCMFanconi anemia group M protein isoform X1. (2057 aa)
TOP3ADNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1124 aa)
RMI1recQ-mediated genome instability protein 1. (626 aa)
MEIOBMeiosis-specific with OB domain-containing protein isoform X1. (474 aa)
RECQL5ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (990 aa)
RPA4LOW QUALITY PROTEIN: replication protein A 30 kDa subunit. (259 aa)
TOP3BDNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (854 aa)
WRNWerner syndrome ATP-dependent helicase isoform X1. (1445 aa)
BLMBloom syndrome protein isoform X1. (1447 aa)
RPA2Replication protein A 32 kDa subunit. (174 aa)
RPA3Replication protein A 14 kDa subunit isoform X1. (121 aa)
TDRD3Tudor domain-containing protein 3. (731 aa)
Your Current Organism:
Neophocaena asiaeorientalis
NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise
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