(5 nodes) Glycogen synthase kinase-3 binding, and Glycogen synthase kinase 3, catalytic domain network (Neophocaena asiaeorientalis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC112392971	LOW QUALITY PROTEIN: proto-oncogene FRAT1-like. (250 aa)
	LOC112392931	GSK-3-binding protein FRAT2-like. (114 aa)
	AKT1	RAC-alpha serine/threonine-protein kinase; Belongs to the protein kinase superfamily. (339 aa)
	GSK3A	Glycogen synthase kinase-3 alpha. (320 aa)
	GSK3B	Glycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily. (433 aa)

Your Current Organism:

Neophocaena asiaeorientalis

NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKT1	GSK3A	A0A341CGU0	A0A341DBH0	RAC-alpha serine/threonine-protein kinase; Belongs to the protein kinase superfamily.	Glycogen synthase kinase-3 alpha.	0.881
AKT1	GSK3B	A0A341CGU0	A0A341DDJ5	RAC-alpha serine/threonine-protein kinase; Belongs to the protein kinase superfamily.	Glycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily.	0.883
GSK3A	AKT1	A0A341DBH0	A0A341CGU0	Glycogen synthase kinase-3 alpha.	RAC-alpha serine/threonine-protein kinase; Belongs to the protein kinase superfamily.	0.881
GSK3A	GSK3B	A0A341DBH0	A0A341DDJ5	Glycogen synthase kinase-3 alpha.	Glycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily.	0.890
GSK3A	LOC112392931	A0A341DBH0	A0A341AJ02	Glycogen synthase kinase-3 alpha.	GSK-3-binding protein FRAT2-like.	0.863
GSK3A	LOC112392971	A0A341DBH0	A0A341AIW8	Glycogen synthase kinase-3 alpha.	LOW QUALITY PROTEIN: proto-oncogene FRAT1-like.	0.863
GSK3B	AKT1	A0A341DDJ5	A0A341CGU0	Glycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily.	RAC-alpha serine/threonine-protein kinase; Belongs to the protein kinase superfamily.	0.883
GSK3B	GSK3A	A0A341DDJ5	A0A341DBH0	Glycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily.	Glycogen synthase kinase-3 alpha.	0.890
GSK3B	LOC112392931	A0A341DDJ5	A0A341AJ02	Glycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily.	GSK-3-binding protein FRAT2-like.	0.999
GSK3B	LOC112392971	A0A341DDJ5	A0A341AIW8	Glycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily.	LOW QUALITY PROTEIN: proto-oncogene FRAT1-like.	0.999
LOC112392931	GSK3A	A0A341AJ02	A0A341DBH0	GSK-3-binding protein FRAT2-like.	Glycogen synthase kinase-3 alpha.	0.863
LOC112392931	GSK3B	A0A341AJ02	A0A341DDJ5	GSK-3-binding protein FRAT2-like.	Glycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily.	0.999
LOC112392931	LOC112392971	A0A341AJ02	A0A341AIW8	GSK-3-binding protein FRAT2-like.	LOW QUALITY PROTEIN: proto-oncogene FRAT1-like.	0.897
LOC112392971	GSK3A	A0A341AIW8	A0A341DBH0	LOW QUALITY PROTEIN: proto-oncogene FRAT1-like.	Glycogen synthase kinase-3 alpha.	0.863
LOC112392971	GSK3B	A0A341AIW8	A0A341DDJ5	LOW QUALITY PROTEIN: proto-oncogene FRAT1-like.	Glycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily.	0.999
LOC112392971	LOC112392931	A0A341AIW8	A0A341AJ02	LOW QUALITY PROTEIN: proto-oncogene FRAT1-like.	GSK-3-binding protein FRAT2-like.	0.897