(47 nodes) Mixed, incl. RAB geranylgeranylation, and GDP dissociation inhibitor network (Neophocaena asiaeorientalis)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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Your Input:
	SLC2A4	Solute carrier family 2, facilitated glucose transporter member 4 isoform X1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (603 aa)
	TBC1D1	TBC1 domain family member 1 isoform X1. (1273 aa)
	GDI2	Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family. (218 aa)
	CHML	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. (651 aa)
	WDR41	WD repeat-containing protein 41 isoform X1. (459 aa)
	RAB8B	Ras-related protein Rab-8B isoform X2. (207 aa)
	RABGGTB	Geranylgeranyl transferase type-2 subunit beta; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C- terminal sequence -XXCC, -XCXC and -CCXX. (331 aa)
	RAB11A	Ras-related protein Rab-11A isoform X1. (218 aa)
	PPM1H	Protein phosphatase 1H isoform X1. (514 aa)
	RAB34	Ras-related protein Rab-34 isoform X1. (268 aa)
	PTAR1	Protein prenyltransferase alpha subunit repeat-containing protein 1. (515 aa)
	RAB39A	Ras-related protein Rab-39A. (282 aa)
	BLZF1	Golgin-45. (401 aa)
	RAB2A	Ras-related protein Rab-2A isoform X1. (226 aa)
	TBC1D20	TBC1 domain family member 20. (403 aa)
	GDI1	Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family. (417 aa)
	SH3BP5	SH3 domain-binding protein 5. (451 aa)
	RAB13	Ras-related protein Rab-13. (203 aa)
	RAB1B	Ras-related protein Rab-1B isoform X2. (223 aa)
	EHBP1L1	EH domain-binding protein 1-like protein 1. (1424 aa)
	RAB3GAP2	Rab3 GTPase-activating protein non-catalytic subunit isoform X1. (1392 aa)
	LOC112404513	Rab proteins geranylgeranyltransferase component A 1-like. (149 aa)
	RAB1A	Ras-related protein Rab-1A. (205 aa)
	RABGGTA	Geranylgeranyl transferase type-2 subunit alpha isoform X1. (579 aa)
	TBC1D4	TBC1 domain family member 4 isoform X1. (1237 aa)
	SMCR8	Guanine nucleotide exchange protein SMCR8. (937 aa)
	CUNH9orf72	Guanine nucleotide exchange C9orf72 homolog isoform X1. (481 aa)
	RAB20	Ras-related protein Rab-20 isoform X1. (235 aa)
	RAB39B	Ras-related protein Rab-39B. (213 aa)
	LOC112407716	F-actin-monooxygenase MICAL2 isoform X1. (1722 aa)
	RILPL2	RILP-like protein 2 isoform X1. (204 aa)
	RILPL1	RILP-like protein 1 isoform X1. (403 aa)
	RAB26	Ras-related protein Rab-26. (256 aa)
	RAB18	Ras-related protein Rab-18. (206 aa)
	LOC112409775	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. (521 aa)
	RAB40B	Ras-related protein Rab-40B isoform X1. (278 aa)
	RAB6A	Ras-related protein Rab-6A isoform X2. (208 aa)
	RAB2B	Ras-related protein Rab-2B isoform X1. (216 aa)
	RABGAP1	Rab GTPase-activating protein 1. (1069 aa)
	RAB14	Ras-related protein Rab-14 isoform X1. (375 aa)
	RAB36	Ras-related protein Rab-36 isoform X1. (354 aa)
	RAB3GAP1	Rab3 GTPase-activating protein catalytic subunit isoform X1. (982 aa)
	MICALL2	MICAL-like protein 2 isoform X1. (948 aa)
	RAB10	Ras-related protein Rab-10. (200 aa)
	LOC112413465	Rab GDP dissociation inhibitor beta-like. (196 aa)
	GORASP2	Golgi reassembly-stacking protein 2 isoform X1. (453 aa)
	RAB8A	Ras-related protein Rab-8A. (278 aa)

Your Current Organism:

Neophocaena asiaeorientalis

NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BLZF1	GORASP2	A0A341B955	A0A341D659	Golgin-45.	Golgi reassembly-stacking protein 2 isoform X1.	0.997
BLZF1	RAB2A	A0A341B955	A0A341B9T9	Golgin-45.	Ras-related protein Rab-2A isoform X1.	0.767
BLZF1	RAB2B	A0A341B955	A0A341CT81	Golgin-45.	Ras-related protein Rab-2B isoform X1.	0.767
CHML	GDI1	A0A341AFJ2	A0A341BGS1	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.	Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family.	0.438
CHML	GDI2	A0A341AFJ2	A0A341AER5	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.	Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family.	0.438
CHML	LOC112404513	A0A341AFJ2	A0A341C178	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.	Rab proteins geranylgeranyltransferase component A 1-like.	0.488
CHML	LOC112409775	A0A341AFJ2	A0A341CME7	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.	0.491
CHML	LOC112413465	A0A341AFJ2	A0A341D5C3	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.	Rab GDP dissociation inhibitor beta-like.	0.438
CHML	PTAR1	A0A341AFJ2	A0A341AW50	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.	Protein prenyltransferase alpha subunit repeat-containing protein 1.	0.859
CHML	RAB10	A0A341AFJ2	A0A341D2A4	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.	Ras-related protein Rab-10.	0.774
CHML	RAB11A	A0A341AFJ2	A0A341ALY9	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.	Ras-related protein Rab-11A isoform X1.	0.594
CHML	RAB13	A0A341AFJ2	A0A341BP40	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.	Ras-related protein Rab-13.	0.599
CHML	RAB14	A0A341AFJ2	A0A341CW72	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.	Ras-related protein Rab-14 isoform X1.	0.645
CHML	RAB18	A0A341AFJ2	A0A341CME0	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.	Ras-related protein Rab-18.	0.628
CHML	RAB1A	A0A341AFJ2	A0A341C1G1	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.	Ras-related protein Rab-1A.	0.817
CHML	RAB1B	A0A341AFJ2	A0A341BPE0	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.	Ras-related protein Rab-1B isoform X2.	0.854
CHML	RAB20	A0A341AFJ2	A0A341C751	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.	Ras-related protein Rab-20 isoform X1.	0.536
CHML	RAB26	A0A341AFJ2	A0A341CKV1	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.	Ras-related protein Rab-26.	0.731
CHML	RAB2A	A0A341AFJ2	A0A341B9T9	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.	Ras-related protein Rab-2A isoform X1.	0.618
CHML	RAB2B	A0A341AFJ2	A0A341CT81	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.	Ras-related protein Rab-2B isoform X1.	0.577