STRINGSTRING
PLCB2 PLCB2 LPAR5 LPAR5 LOC112390757 LOC112390757 F2R F2R GNB3 GNB3 PTGER3 PTGER3 GNG12 GNG12 GNG2 GNG2 HTR1E HTR1E ARRB2 ARRB2 PTGER2 PTGER2 LOC112394009 LOC112394009 NPFF NPFF DRD3 DRD3 GCG GCG FAP FAP ADRB2 ADRB2 GNAI2 GNAI2 LOC112394380 LOC112394380 GNAI1 GNAI1 LOC112395611 LOC112395611 HTR4 HTR4 GPR119 GPR119 GNA15 GNA15 HTR7 HTR7 GNA14 GNA14 HRH1 HRH1 GNA11 GNA11 GNG7 GNG7 GRK3 GRK3 CHRM2 CHRM2 ADRA1D ADRA1D GNGT2 GNGT2 ADRA2C ADRA2C GIP GIP GNB2 GNB2 HCRT HCRT GRK6 GRK6 RCVRN RCVRN GLP2R GLP2R APLNR APLNR GNG3 GNG3 CHRM1 CHRM1 GRK2 GRK2 LOC112402005 LOC112402005 CHRM4 CHRM4 LOC112402359 LOC112402359 DRD4 DRD4 LOC112402387 LOC112402387 LOC112402955 LOC112402955 PREX1 PREX1 HTR6 HTR6 ADRA1B ADRA1B LOC112402987 LOC112402987 GNAO1 GNAO1 GRK1 GRK1 LOC112404739 LOC112404739 DRD1 DRD1 ADORA2B ADORA2B VIPR2 VIPR2 DRD2 DRD2 NPFFR2 NPFFR2 VIPR1 VIPR1 HCRTR2 HCRTR2 PTGER4 PTGER4 ADCYAP1R1 ADCYAP1R1 LPAR6 LPAR6 GNB4 GNB4 CHRM5 CHRM5 ADRB1 ADRB1 ARR3 ARR3 RHO RHO GRK5 GRK5 LOC112407797 LOC112407797 LPAR1 LPAR1 CLTC CLTC HTR1B HTR1B HTR1A HTR1A LOC112408493 LOC112408493 LPAR4 LPAR4 LOC112408429 LOC112408429 ADGRD1 ADGRD1 ADCYAP1 ADCYAP1 GNB1 GNB1 GNG13 GNG13 GCGR GCGR HTR1F HTR1F CHRM3 CHRM3 GNG4 GNG4 GRM5 GRM5 PDCL PDCL ARRB1 ARRB1 GPR35 GPR35 PLCB1 PLCB1 GNAZ GNAZ NPFFR1 NPFFR1 HTR1D HTR1D HCRTR1 HCRTR1 GNG11 GNG11 GLP1R GLP1R ADGRL1 ADGRL1 F2RL3 F2RL3 PTGER1 PTGER1 GNG14 GNG14 ADRA1A ADRA1A LPAR3 LPAR3 GNG5 GNG5 GNGT1 GNGT1 GIPR GIPR LPAR2 LPAR2 GRK7 GRK7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1185 aa)
LPAR5Lysophosphatidic acid receptor 5; Belongs to the G-protein coupled receptor 1 family. (367 aa)
LOC112390757Olfactory receptor. (317 aa)
F2RProteinase-activated receptor 1; Belongs to the G-protein coupled receptor 1 family. (427 aa)
GNB3Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 isoform X1. (340 aa)
PTGER3Prostaglandin E2 receptor EP3 subtype isoform X1. (389 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (86 aa)
HTR1E5-hydroxytryptamine receptor 1E. (365 aa)
ARRB2Beta-arrestin-2. (409 aa)
PTGER2Prostaglandin E2 receptor EP2 subtype; Belongs to the G-protein coupled receptor 1 family. (354 aa)
LOC112394009Olfactory receptor. (305 aa)
NPFFLOW QUALITY PROTEIN: pro-FMRFamide-related neuropeptide FF. (181 aa)
DRD3D(3) dopamine receptor isoform X1; Belongs to the G-protein coupled receptor 1 family. (400 aa)
GCGGlucagon isoform X1. (180 aa)
FAPProlyl endopeptidase FAP; Belongs to the peptidase S9B family. (760 aa)
ADRB2Beta-2 adrenergic receptor isoform X3. (418 aa)
GNAI2Guanine nucleotide-binding protein G(I) subunit alpha-2. (355 aa)
LOC112394380Olfactory receptor. (313 aa)
GNAI1Guanine nucleotide-binding protein G(I) subunit alpha-1. (354 aa)
LOC112395611Guanine nucleotide-binding protein G(Q) subunit alpha. (301 aa)
HTR45-hydroxytryptamine receptor 4; Belongs to the G-protein coupled receptor 1 family. (402 aa)
GPR119Glucose-dependent insulinotropic receptor; Belongs to the G-protein coupled receptor 1 family. (335 aa)
GNA15Guanine nucleotide-binding protein subunit alpha-15. (374 aa)
HTR75-hydroxytryptamine receptor 7 isoform X1; Belongs to the G-protein coupled receptor 1 family. (471 aa)
GNA14Guanine nucleotide-binding protein subunit alpha-14. (355 aa)
HRH1Histamine H1 receptor; Belongs to the G-protein coupled receptor 1 family. (487 aa)
GNA11Guanine nucleotide-binding protein subunit alpha-11. (337 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GRK3G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (665 aa)
CHRM2Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (466 aa)
ADRA1Dalpha-1D adrenergic receptor. (569 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
ADRA2Calpha-2C adrenergic receptor. (518 aa)
GIPGastric inhibitory polypeptide isoform X1. (143 aa)
GNB2Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2. (340 aa)
HCRTOrexin; Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested. Belongs to the orexin family. (131 aa)
GRK6G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (587 aa)
RCVRNRecoverin. (202 aa)
GLP2RGlucagon-like peptide 2 receptor; Belongs to the G-protein coupled receptor 2 family. (553 aa)
APLNRApelin receptor; Belongs to the G-protein coupled receptor 1 family. (383 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
CHRM1Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (459 aa)
GRK2G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (647 aa)
LOC112402005Olfactory receptor 10V1-like. (307 aa)
CHRM4Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (478 aa)
LOC112402359Olfactory receptor. (310 aa)
DRD4D(4) dopamine receptor. (205 aa)
LOC112402387Olfactory receptor. (309 aa)
LOC112402955Guanine nucleotide-binding protein G(S) subunit alpha isoforms XLas-like. (946 aa)
PREX1Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein isoform X1. (1674 aa)
HTR65-hydroxytryptamine receptor 6; Belongs to the G-protein coupled receptor 1 family. (440 aa)
ADRA1Balpha-1B adrenergic receptor. (610 aa)
LOC112402987Neuroendocrine secretory protein 55-like. (241 aa)
GNAO1LOW QUALITY PROTEIN: guanine nucleotide-binding protein G(O) subunit alpha. (363 aa)
GRK1Rhodopsin kinase. (846 aa)
LOC112404739Olfactory receptor. (320 aa)
DRD1D(1A) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (452 aa)
ADORA2BAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (333 aa)
VIPR2Vasoactive intestinal polypeptide receptor 2; Belongs to the G-protein coupled receptor 2 family. (599 aa)
DRD2D(2) dopamine receptor isoform X2; Belongs to the G-protein coupled receptor 1 family. (443 aa)
NPFFR2LOW QUALITY PROTEIN: neuropeptide FF receptor 2. (419 aa)
VIPR1Vasoactive intestinal polypeptide receptor 1 isoform X1; Belongs to the G-protein coupled receptor 2 family. (458 aa)
HCRTR2Orexin receptor type 2 isoform X1; Belongs to the G-protein coupled receptor 1 family. (457 aa)
PTGER4Prostaglandin E2 receptor EP4 subtype; Belongs to the G-protein coupled receptor 1 family. (486 aa)
ADCYAP1R1Pituitary adenylate cyclase-activating polypeptide type I receptor isoform X1; Belongs to the G-protein coupled receptor 2 family. (496 aa)
LPAR6Lysophosphatidic acid receptor 6; Belongs to the G-protein coupled receptor 1 family. (344 aa)
GNB4Guanine nucleotide-binding protein subunit beta-4 isoform X1. (340 aa)
CHRM5Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (533 aa)
ADRB1Beta-1 adrenergic receptor. (562 aa)
ARR3arrestin-C. (393 aa)
RHORhodopsin. (348 aa)
GRK5G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (590 aa)
LOC112407797LOW QUALITY PROTEIN: olfactory receptor 5-like; Belongs to the G-protein coupled receptor 1 family. (322 aa)
LPAR1Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (364 aa)
CLTCClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1675 aa)
HTR1B5-hydroxytryptamine receptor 1B. (399 aa)
HTR1A5-hydroxytryptamine receptor 1A. (422 aa)
LOC112408493LOW QUALITY PROTEIN: olfactory receptor 13-like. (306 aa)
LPAR4Lysophosphatidic acid receptor 4; Belongs to the G-protein coupled receptor 1 family. (370 aa)
LOC112408429LOW QUALITY PROTEIN: olfactory receptor 6B1. (303 aa)
ADGRD1Adhesion G-protein coupled receptor D1 isoform X1; Belongs to the G-protein coupled receptor 2 family. (903 aa)
ADCYAP1Pituitary adenylate cyclase-activating polypeptide. (176 aa)
GNB1Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1. (340 aa)
GNG13Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13. (67 aa)
GCGRGlucagon receptor; Belongs to the G-protein coupled receptor 2 family. (479 aa)
HTR1F5-hydroxytryptamine receptor 1F. (365 aa)
CHRM3Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (590 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
GRM5LOW QUALITY PROTEIN: metabotropic glutamate receptor 5. (1106 aa)
PDCLPhosducin-like protein. (301 aa)
ARRB1Beta-arrestin-1 isoform X1. (418 aa)
GPR35G-protein coupled receptor 35 isoform X1; Belongs to the G-protein coupled receptor 1 family. (364 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1211 aa)
GNAZGuanine nucleotide-binding protein G(Z) subunit alpha. (355 aa)
NPFFR1LOW QUALITY PROTEIN: neuropeptide FF receptor 1; Belongs to the G-protein coupled receptor 1 family. (620 aa)
HTR1D5-hydroxytryptamine receptor 1D. (400 aa)
HCRTR1Orexin receptor type 1; Belongs to the G-protein coupled receptor 1 family. (425 aa)
GNG11Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 isoform X1. (95 aa)
GLP1RGlucagon-like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family. (442 aa)
ADGRL1Adhesion G protein-coupled receptor L1 isoform X1; Belongs to the G-protein coupled receptor 2 family. (1468 aa)
F2RL3Proteinase-activated receptor 4; Belongs to the G-protein coupled receptor 1 family. (380 aa)
PTGER1Prostaglandin E2 receptor EP1 subtype isoform X1. (437 aa)
GNG14LOW QUALITY PROTEIN: putative guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-14. (101 aa)
ADRA1Aalpha-1A adrenergic receptor. (466 aa)
LPAR3Lysophosphatidic acid receptor 3; Belongs to the G-protein coupled receptor 1 family. (355 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
GIPRGastric inhibitory polypeptide receptor; Belongs to the G-protein coupled receptor 2 family. (466 aa)
LPAR2Lysophosphatidic acid receptor 2; Belongs to the G-protein coupled receptor 1 family. (351 aa)
GRK7G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (551 aa)
Your Current Organism:
Neophocaena asiaeorientalis
NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise
Server load: low (16%) [HD]