node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ASNA1 | BAG6 | A0A341D7J6 | A0A341AV44 | ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...] | Large proline-rich protein BAG6 isoform X1. | 0.786 |
ASNA1 | GET4 | A0A341D7J6 | A0A341CZK8 | ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...] | Golgi to ER traffic protein 4 homolog. | 0.999 |
ASNA1 | RNF126 | A0A341D7J6 | A0A341B0R0 | ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...] | LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase RNF126. | 0.557 |
ASNA1 | SGTA | A0A341D7J6 | A0A341B125 | ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...] | Small glutamine-rich tetratricopeptide repeat-containing protein alpha. | 0.884 |
BAG6 | ASNA1 | A0A341AV44 | A0A341D7J6 | Large proline-rich protein BAG6 isoform X1. | ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...] | 0.786 |
BAG6 | GET4 | A0A341AV44 | A0A341CZK8 | Large proline-rich protein BAG6 isoform X1. | Golgi to ER traffic protein 4 homolog. | 0.979 |
BAG6 | RNF126 | A0A341AV44 | A0A341B0R0 | Large proline-rich protein BAG6 isoform X1. | LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase RNF126. | 0.977 |
BAG6 | SGTA | A0A341AV44 | A0A341B125 | Large proline-rich protein BAG6 isoform X1. | Small glutamine-rich tetratricopeptide repeat-containing protein alpha. | 0.911 |
GET4 | ASNA1 | A0A341CZK8 | A0A341D7J6 | Golgi to ER traffic protein 4 homolog. | ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...] | 0.999 |
GET4 | BAG6 | A0A341CZK8 | A0A341AV44 | Golgi to ER traffic protein 4 homolog. | Large proline-rich protein BAG6 isoform X1. | 0.979 |
GET4 | RNF126 | A0A341CZK8 | A0A341B0R0 | Golgi to ER traffic protein 4 homolog. | LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase RNF126. | 0.826 |
GET4 | SGTA | A0A341CZK8 | A0A341B125 | Golgi to ER traffic protein 4 homolog. | Small glutamine-rich tetratricopeptide repeat-containing protein alpha. | 0.958 |
RNF126 | ASNA1 | A0A341B0R0 | A0A341D7J6 | LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase RNF126. | ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...] | 0.557 |
RNF126 | BAG6 | A0A341B0R0 | A0A341AV44 | LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase RNF126. | Large proline-rich protein BAG6 isoform X1. | 0.977 |
RNF126 | GET4 | A0A341B0R0 | A0A341CZK8 | LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase RNF126. | Golgi to ER traffic protein 4 homolog. | 0.826 |
RNF126 | SGTA | A0A341B0R0 | A0A341B125 | LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase RNF126. | Small glutamine-rich tetratricopeptide repeat-containing protein alpha. | 0.694 |
SGTA | ASNA1 | A0A341B125 | A0A341D7J6 | Small glutamine-rich tetratricopeptide repeat-containing protein alpha. | ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...] | 0.884 |
SGTA | BAG6 | A0A341B125 | A0A341AV44 | Small glutamine-rich tetratricopeptide repeat-containing protein alpha. | Large proline-rich protein BAG6 isoform X1. | 0.911 |
SGTA | GET4 | A0A341B125 | A0A341CZK8 | Small glutamine-rich tetratricopeptide repeat-containing protein alpha. | Golgi to ER traffic protein 4 homolog. | 0.958 |
SGTA | RNF126 | A0A341B125 | A0A341B0R0 | Small glutamine-rich tetratricopeptide repeat-containing protein alpha. | LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase RNF126. | 0.694 |