25 items (Neophocaena asiaeorientalis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DLL4	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa)
	SRF	Serum response factor isoform X1. (535 aa)
	EDN1	Endothelin-1. (202 aa)
	IHH	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (410 aa)
	NRARP	Notch-regulated ankyrin repeat-containing protein. (114 aa)
	ENG	Endoglin. (652 aa)
	GNA13	Guanine nucleotide-binding protein subunit alpha-13. (282 aa)
	LOC112407988	Secreted frizzled-related protein 2. (294 aa)
	LOC112407979	Secreted frizzled-related protein 2-like. (105 aa)
	PLXND1	plexin-D1. (1847 aa)
	CTNNB1	Catenin beta-1. (781 aa)
	COL4A1	Collagen alpha-1(IV) chain. (1730 aa)
	GBX2	Homeobox protein GBX-2 isoform X1. (348 aa)
	NFATC4	Nuclear factor of activated T-cells, cytoplasmic 4 isoform X1. (831 aa)
	TBX20	T-box transcription factor TBX20. (449 aa)
	KDR	Vascular endothelial growth factor receptor 2 isoform X4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
	STK4	Serine/threonine-protein kinase 4 isoform X1. (487 aa)
	RBM15	Putative RNA-binding protein 15. (962 aa)
	LEF1	Lymphoid enhancer-binding factor 1 isoform X1. (414 aa)
	SHH	Sonic hedgehog protein. (328 aa)
	GDF2	Growth/differentiation factor 2. (431 aa)
	SEMA3E	semaphorin-3E; Belongs to the semaphorin family. (715 aa)
	EDNRA	Endothelin-1 receptor isoform X1; Belongs to the G-protein coupled receptor 1 family. (427 aa)
	PPP3R2	LOW QUALITY PROTEIN: calcineurin subunit B type 2. (229 aa)
	FGF8	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)

Your Current Organism:

Neophocaena asiaeorientalis

NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CTNNB1	DLL4	A0A341C5R9	A0A341AED5	Catenin beta-1.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.464
CTNNB1	EDN1	A0A341C5R9	A0A341CZ89	Catenin beta-1.	Endothelin-1.	0.416
CTNNB1	FGF8	A0A341C5R9	A0A341AJJ9	Catenin beta-1.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.544
CTNNB1	IHH	A0A341C5R9	A0A341CW65	Catenin beta-1.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.515
CTNNB1	KDR	A0A341C5R9	A0A341BL62	Catenin beta-1.	Vascular endothelial growth factor receptor 2 isoform X4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.922
CTNNB1	LEF1	A0A341C5R9	A0A341B487	Catenin beta-1.	Lymphoid enhancer-binding factor 1 isoform X1.	0.999
CTNNB1	LOC112407979	A0A341C5R9	A0A341CF44	Catenin beta-1.	Secreted frizzled-related protein 2-like.	0.593
CTNNB1	LOC112407988	A0A341C5R9	A0A341CH64	Catenin beta-1.	Secreted frizzled-related protein 2.	0.593
CTNNB1	SHH	A0A341C5R9	A0A341AWS9	Catenin beta-1.	Sonic hedgehog protein.	0.683
DLL4	CTNNB1	A0A341AED5	A0A341C5R9	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Catenin beta-1.	0.464
DLL4	NRARP	A0A341AED5	A0A341CVL0	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Notch-regulated ankyrin repeat-containing protein.	0.592
EDN1	CTNNB1	A0A341CZ89	A0A341C5R9	Endothelin-1.	Catenin beta-1.	0.416
EDN1	EDNRA	A0A341CZ89	A0A341AMR3	Endothelin-1.	Endothelin-1 receptor isoform X1; Belongs to the G-protein coupled receptor 1 family.	0.998
EDN1	ENG	A0A341CZ89	A0A341CUK2	Endothelin-1.	Endoglin.	0.579
EDN1	FGF8	A0A341CZ89	A0A341AJJ9	Endothelin-1.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.412
EDN1	KDR	A0A341CZ89	A0A341BL62	Endothelin-1.	Vascular endothelial growth factor receptor 2 isoform X4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.568
EDNRA	EDN1	A0A341AMR3	A0A341CZ89	Endothelin-1 receptor isoform X1; Belongs to the G-protein coupled receptor 1 family.	Endothelin-1.	0.998
EDNRA	GNA13	A0A341AMR3	A0A341CP55	Endothelin-1 receptor isoform X1; Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide-binding protein subunit alpha-13.	0.886
ENG	EDN1	A0A341CUK2	A0A341CZ89	Endoglin.	Endothelin-1.	0.579
ENG	GDF2	A0A341CUK2	A0A341AWI8	Endoglin.	Growth/differentiation factor 2.	0.677