STRINGSTRING
BMPR1A BMPR1A SOX9 SOX9 WNT2 WNT2 IRS2 IRS2 CTNNB1 CTNNB1 FGF9 FGF9 LRP5 LRP5 FOXF1 FOXF1 SIX1 SIX1 KDR KDR WNT5A WNT5A PRRX1 PRRX1 SHOX2 SHOX2 SHH SHH SMO SMO IHH IHH CHRD CHRD
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
SOX9Transcription factor SOX-9. (486 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
IRS2Insulin receptor substrate 2. (702 aa)
CTNNB1Catenin beta-1. (781 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
LRP5Low-density lipoprotein receptor-related protein 5 isoform X1. (1461 aa)
FOXF1Forkhead box protein F1. (375 aa)
SIX1Homeobox protein SIX1. (284 aa)
KDRVascular endothelial growth factor receptor 2 isoform X4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
PRRX1Paired mesoderm homeobox protein 1. (245 aa)
SHOX2Short stature homeobox protein 2 isoform X1. (333 aa)
SHHSonic hedgehog protein. (328 aa)
SMOSmoothened homolog; Belongs to the G-protein coupled receptor Fz/Smo family. (783 aa)
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (410 aa)
CHRDChordin. (851 aa)
Your Current Organism:
Neophocaena asiaeorientalis
NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise
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