17 items (Neophocaena asiaeorientalis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC112415649	LOW QUALITY PROTEIN: ATPase family AAA domain-containing protein 1-like. (498 aa)
	SYK	Tyrosine-protein kinase. (626 aa)
	PLCG2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
	ARRB2	Beta-arrestin-2. (409 aa)
	APELA	Apelin receptor early endogenous ligand. (54 aa)
	PCSK9	Proprotein convertase subtilisin/kexin type 9. (703 aa)
	FMR1	Synaptic functional regulator FMR1 isoform X1. (632 aa)
	EGF	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1238 aa)
	SFRP4	Secreted frizzled-related protein 4 isoform X1. (346 aa)
	ATAD1	ATPase family AAA domain-containing protein 1; Belongs to the AAA ATPase family. (380 aa)
	INSR	Tyrosine-protein kinase receptor. (1382 aa)
	SCYL2	SCY1-like protein 2 isoform X1. (928 aa)
	AHI1	Jouberin isoform X1. (1178 aa)
	GREM1	Gremlin. (184 aa)
	PICK1	PRKCA-binding protein. (417 aa)
	ARRB1	Beta-arrestin-1 isoform X1. (418 aa)
	WNT3A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)

Your Current Organism:

Neophocaena asiaeorientalis

NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARRB1	ARRB2	A0A341CV59	A0A341ALM3	Beta-arrestin-1 isoform X1.	Beta-arrestin-2.	0.875
ARRB1	PICK1	A0A341CV59	A0A341CRQ0	Beta-arrestin-1 isoform X1.	PRKCA-binding protein.	0.416
ARRB2	ARRB1	A0A341ALM3	A0A341CV59	Beta-arrestin-2.	Beta-arrestin-1 isoform X1.	0.875
ARRB2	PICK1	A0A341ALM3	A0A341CRQ0	Beta-arrestin-2.	PRKCA-binding protein.	0.461
ATAD1	PICK1	A0A341BCE4	A0A341CRQ0	ATPase family AAA domain-containing protein 1; Belongs to the AAA ATPase family.	PRKCA-binding protein.	0.462
EGF	INSR	A0A341B7T5	A0A341BIP5	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Tyrosine-protein kinase receptor.	0.873
EGF	PCSK9	A0A341B7T5	A0A341AYC1	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Proprotein convertase subtilisin/kexin type 9.	0.883
EGF	PLCG2	A0A341B7T5	A0A341ALA1	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.603
EGF	WNT3A	A0A341B7T5	A0A341D345	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.611
INSR	EGF	A0A341BIP5	A0A341B7T5	Tyrosine-protein kinase receptor.	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	0.873
INSR	PLCG2	A0A341BIP5	A0A341ALA1	Tyrosine-protein kinase receptor.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.516
LOC112415649	PICK1	A0A341DCF3	A0A341CRQ0	LOW QUALITY PROTEIN: ATPase family AAA domain-containing protein 1-like.	PRKCA-binding protein.	0.462
PCSK9	EGF	A0A341AYC1	A0A341B7T5	Proprotein convertase subtilisin/kexin type 9.	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	0.883
PICK1	ARRB1	A0A341CRQ0	A0A341CV59	PRKCA-binding protein.	Beta-arrestin-1 isoform X1.	0.416
PICK1	ARRB2	A0A341CRQ0	A0A341ALM3	PRKCA-binding protein.	Beta-arrestin-2.	0.461
PICK1	ATAD1	A0A341CRQ0	A0A341BCE4	PRKCA-binding protein.	ATPase family AAA domain-containing protein 1; Belongs to the AAA ATPase family.	0.462
PICK1	LOC112415649	A0A341CRQ0	A0A341DCF3	PRKCA-binding protein.	LOW QUALITY PROTEIN: ATPase family AAA domain-containing protein 1-like.	0.462
PLCG2	EGF	A0A341ALA1	A0A341B7T5	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	0.603
PLCG2	INSR	A0A341ALA1	A0A341BIP5	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	Tyrosine-protein kinase receptor.	0.516
PLCG2	SYK	A0A341ALA1	A0A341ADP3	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	Tyrosine-protein kinase.	0.993