STRINGSTRING
PLXND1 PLXND1 ZFPM2 ZFPM2 LRP2 LRP2 JAG1 JAG1 FGF8 FGF8 ATF2 ATF2 MEF2C MEF2C GJA5 GJA5 BMP4 BMP4 SEMA3C SEMA3C LOC112390775 LOC112390775 BMPR1A BMPR1A DVL2 DVL2 ZFPM1 ZFPM1 EDNRA EDNRA NPY1R NPY1R SMAD6 SMAD6 NPY5R NPY5R BMPR2 BMPR2 TWIST1 TWIST1 HEYL HEYL NRP2 NRP2 EYA1 EYA1 ISL1 ISL1 CITED2 CITED2 FOXH1 FOXH1 TBX3 TBX3 SEC24B SEC24B SOX17 SOX17 ELN ELN WNT5A WNT5A SIX1 SIX1 HIF1A HIF1A DHRS3 DHRS3 TBX20 TBX20 HAND2 HAND2 HES1 HES1 NKX2-5 NKX2-5 NIPBL NIPBL JUN JUN PRLHR PRLHR ILK ILK PARVA PARVA LOC112407979 LOC112407979 SMAD4 SMAD4 WNT11 WNT11 NOG NOG TBX2 TBX2 GATA6 GATA6 LOC112407988 LOC112407988 HEY2 HEY2 FZD2 FZD2 ENG ENG NOTCH1 NOTCH1 CRKL CRKL EDN1 EDN1 NPY2R NPY2R
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PLXND1plexin-D1. (1847 aa)
ZFPM2Zinc finger protein ZFPM2. (1150 aa)
LRP2Low-density lipoprotein receptor-related protein 2 isoform X1. (4651 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1177 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2 isoform X1. (505 aa)
MEF2CMyocyte-specific enhancer factor 2C isoform X4. (483 aa)
GJA5Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (358 aa)
BMP4Bone morphogenetic protein 4 isoform X1. (420 aa)
SEMA3Csemaphorin-3C; Belongs to the semaphorin family. (751 aa)
LOC112390775Folate receptor alpha-like. (251 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
DVL2Segment polarity protein dishevelled homolog DVL-2 isoform X1. (785 aa)
ZFPM1Zinc finger protein ZFPM1. (998 aa)
EDNRAEndothelin-1 receptor isoform X1; Belongs to the G-protein coupled receptor 1 family. (427 aa)
NPY1RNeuropeptide Y receptor type 1; Belongs to the G-protein coupled receptor 1 family. (383 aa)
SMAD6LOW QUALITY PROTEIN: mothers against decapentaplegic homolog 6. (422 aa)
NPY5RNeuropeptide Y receptor type 5. (456 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1012 aa)
TWIST1LOW QUALITY PROTEIN: twist-related protein 1. (152 aa)
HEYLHairy/enhancer-of-split related with YRPW motif-like protein isoform X1. (357 aa)
NRP2Neuropilin; Belongs to the neuropilin family. (931 aa)
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (589 aa)
ISL1Insulin gene enhancer protein ISL-1. (349 aa)
CITED2Cbp/p300-interacting transactivator 2. (263 aa)
FOXH1Forkhead box protein H1. (360 aa)
TBX3LOW QUALITY PROTEIN: T-box transcription factor TBX3. (734 aa)
SEC24BProtein transport protein Sec24B isoform X1. (1168 aa)
SOX17LOW QUALITY PROTEIN: transcription factor SOX-17. (207 aa)
ELNElastin isoform X1. (744 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
SIX1Homeobox protein SIX1. (284 aa)
HIF1AHypoxia-inducible factor 1-alpha. (823 aa)
DHRS3Short-chain dehydrogenase/reductase 3 isoform X1. (368 aa)
TBX20T-box transcription factor TBX20. (449 aa)
HAND2Heart- and neural crest derivatives-expressed protein 2. (208 aa)
HES1Transcription factor HES-1. (280 aa)
NKX2-5Homeobox protein Nkx-2.5. (323 aa)
NIPBLNipped-B protein. (2803 aa)
JUNLOW QUALITY PROTEIN: transcription factor AP-1; Belongs to the bZIP family. (284 aa)
PRLHRProlactin-releasing peptide receptor; Belongs to the G-protein coupled receptor 1 family. (370 aa)
ILKIntegrin-linked protein kinase isoform X1. (485 aa)
PARVAAlpha-parvin. (347 aa)
LOC112407979Secreted frizzled-related protein 2-like. (105 aa)
SMAD4Mothers against decapentaplegic homolog. (599 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
TBX2T-box transcription factor TBX2. (588 aa)
GATA6Transcription factor GATA-6. (448 aa)
LOC112407988Secreted frizzled-related protein 2. (294 aa)
HEY2Hairy/enhancer-of-split related with YRPW motif protein 2. (337 aa)
FZD2Frizzled-2; Belongs to the G-protein coupled receptor Fz/Smo family. (709 aa)
ENGEndoglin. (652 aa)
NOTCH1LOW QUALITY PROTEIN: neurogenic locus notch homolog protein 1. (2633 aa)
CRKLCrk-like protein. (303 aa)
EDN1Endothelin-1. (202 aa)
NPY2RNeuropeptide Y receptor type 2; Belongs to the G-protein coupled receptor 1 family. (384 aa)
Your Current Organism:
Neophocaena asiaeorientalis
NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise
Server load: low (18%) [HD]