STRINGSTRING
MEF2C MEF2C GSK3A GSK3A PPP1R13L PPP1R13L TGFB1 TGFB1 NPY2R NPY2R MESP1 MESP1 CPE CPE NOTCH1 NOTCH1 ENG ENG RYR2 RYR2 HAND1 HAND1 POU4F1 POU4F1 HEY2 HEY2 MYL2 MYL2 LOC112407988 LOC112407988 NOG NOG SMAD4 SMAD4 LOC112407979 LOC112407979 PTCD2 PTCD2 LRP2 LRP2 SMAD7 SMAD7 GRHL2 GRHL2 ZFPM2 ZFPM2 HEG1 HEG1 LOC112406076 LOC112406076 SMARCD3 SMARCD3 NKX2-5 NKX2-5 PROX1 PROX1 HAND2 HAND2 MYL3 MYL3 TBX20 TBX20 MYBPC3 MYBPC3 TNNT2 TNNT2 TNNI1 TNNI1 HIF1A HIF1A PKP2 PKP2 TNNC1 TNNC1 MYL10 MYL10 CHD7 CHD7 MED1 MED1 TBX5 TBX5 FOXH1 FOXH1 SOX4 SOX4 ISL1 ISL1 DSP DSP HEYL HEYL BMP10 BMP10 NPY5R NPY5R EDNRA EDNRA FOXF1 FOXF1 TGFBR1 TGFBR1 JAG1 JAG1 DLL4 DLL4 SEMA3C SEMA3C GATA3 GATA3 BMPR1A BMPR1A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MEF2CMyocyte-specific enhancer factor 2C isoform X4. (483 aa)
GSK3AGlycogen synthase kinase-3 alpha. (320 aa)
PPP1R13LrelA-associated inhibitor. (808 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa)
NPY2RNeuropeptide Y receptor type 2; Belongs to the G-protein coupled receptor 1 family. (384 aa)
MESP1Mesoderm posterior protein 1. (265 aa)
CPECarboxypeptidase E. (364 aa)
NOTCH1LOW QUALITY PROTEIN: neurogenic locus notch homolog protein 1. (2633 aa)
ENGEndoglin. (652 aa)
RYR2Ryanodine receptor 2. (4971 aa)
HAND1Heart- and neural crest derivatives-expressed protein 1. (218 aa)
POU4F1POU domain protein. (320 aa)
HEY2Hairy/enhancer-of-split related with YRPW motif protein 2. (337 aa)
MYL2Myosin regulatory light chain 2, ventricular/cardiac muscle isoform. (166 aa)
LOC112407988Secreted frizzled-related protein 2. (294 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
SMAD4Mothers against decapentaplegic homolog. (599 aa)
LOC112407979Secreted frizzled-related protein 2-like. (105 aa)
PTCD2LOW QUALITY PROTEIN: pentatricopeptide repeat-containing protein 2, mitochondrial. (384 aa)
LRP2Low-density lipoprotein receptor-related protein 2 isoform X1. (4651 aa)
SMAD7Mothers against decapentaplegic homolog. (426 aa)
GRHL2Grainyhead-like protein 2 homolog isoform X1. (625 aa)
ZFPM2Zinc finger protein ZFPM2. (1150 aa)
HEG1Protein HEG homolog 1. (1138 aa)
LOC112406076Protein HEG homolog 1-like. (419 aa)
SMARCD3annotation not available (495 aa)
NKX2-5Homeobox protein Nkx-2.5. (323 aa)
PROX1Prospero homeobox protein 1 isoform X1. (737 aa)
HAND2Heart- and neural crest derivatives-expressed protein 2. (208 aa)
MYL3Myosin light chain 3. (197 aa)
TBX20T-box transcription factor TBX20. (449 aa)
MYBPC3Myosin-binding protein C, cardiac-type. (1277 aa)
TNNT2Troponin T, cardiac muscle isoform X1. (333 aa)
TNNI1Troponin I, slow skeletal muscle. (166 aa)
HIF1AHypoxia-inducible factor 1-alpha. (823 aa)
PKP2Plakophilin-2. (826 aa)
TNNC1Troponin C, slow skeletal and cardiac muscles. (161 aa)
MYL10Myosin regulatory light chain 10. (147 aa)
CHD7LOW QUALITY PROTEIN: chromodomain-helicase-DNA-binding protein 7. (3000 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1579 aa)
TBX5T-box transcription factor TBX5. (519 aa)
FOXH1Forkhead box protein H1. (360 aa)
SOX4Transcription factor SOX-4. (285 aa)
ISL1Insulin gene enhancer protein ISL-1. (349 aa)
DSPDesmoplakin isoform X1. (2874 aa)
HEYLHairy/enhancer-of-split related with YRPW motif-like protein isoform X1. (357 aa)
BMP10Bone morphogenetic protein 10. (423 aa)
NPY5RNeuropeptide Y receptor type 5. (456 aa)
EDNRAEndothelin-1 receptor isoform X1; Belongs to the G-protein coupled receptor 1 family. (427 aa)
FOXF1Forkhead box protein F1. (375 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (438 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1177 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa)
SEMA3Csemaphorin-3C; Belongs to the semaphorin family. (751 aa)
GATA3Trans-acting T-cell-specific transcription factor GATA-3 isoform X1. (444 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
Your Current Organism:
Neophocaena asiaeorientalis
NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise
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