STRINGSTRING
LOC112397760 LOC112397760 BMPR1A BMPR1A NR2F2 NR2F2 PHOX2B PHOX2B MYOZ2 MYOZ2 MYOD1 MYOD1 HOXD10 HOXD10 KRAS KRAS DLL4 DLL4 COL3A1 COL3A1 NPHS1 NPHS1 CHRNA1 CHRNA1 ACTC1 ACTC1 MEF2C MEF2C HOXD9 HOXD9 TGFBR1 TGFBR1 CAVIN4 CAVIN4 ZFPM1 ZFPM1 LBX1 LBX1 EDNRA EDNRA STAC3 STAC3 NF1 NF1 PPP3CA PPP3CA MYL6 MYL6 NR4A1 NR4A1 COPRS COPRS MYF6 MYF6 CHKB CHKB R3HDM2 R3HDM2 WNT10B WNT10B MYF5 MYF5 RHOA RHOA EP300 EP300 DAG1 DAG1 BMP10 BMP10 MSC MSC SHH SHH HEYL HEYL ACTN1 ACTN1 DSP DSP SPG11 SPG11 SHOX2 SHOX2 ISL1 ISL1 DMRTA2 DMRTA2 DNER DNER CHRND CHRND CITED2 CITED2 ANKRD1 ANKRD1 PPP3CB PPP3CB P2RX2 P2RX2 PLEC PLEC CDON CDON MTM1 MTM1 FOXH1 FOXH1 MYOZ1 MYOZ1 MED1 MED1 EID2 EID2 UNC45B UNC45B XBP1 XBP1 LIF LIF MYH14 MYH14 VRK3 VRK3 TGFB1 TGFB1 FXR1 FXR1 ANKRD33B ANKRD33B MEOX2 MEOX2 SGCE SGCE ID3 ID3 SELENON SELENON EGLN1 EGLN1 UNC45A UNC45A ITGB1 ITGB1 MSX1 MSX1 LEMD2 LEMD2 POPDC2 POPDC2 METTL8 METTL8 MYMX MYMX JPH1 JPH1 WNT3A WNT3A ACTA1 ACTA1 EGR2 EGR2 ARID5B ARID5B BMP2 BMP2 CSRP3 CSRP3 GPCPD1 GPCPD1 CCNT2 CCNT2 R3HDM1 R3HDM1 DES DES PAX5 PAX5 NOTCH1 NOTCH1 ENG ENG SMO SMO GTF3C5 GTF3C5 CFL2 CFL2 STRA6 STRA6 MAFF MAFF KLHL41 KLHL41 RYR2 RYR2 HAND1 HAND1 MKX MKX FRG1 FRG1 FZD2 FZD2 PSIP1 PSIP1 DMD DMD POU4F1 POU4F1 GSC GSC SOX8 SOX8 FHL1 FHL1 ZBTB42 ZBTB42 HEY2 HEY2 TCF21 TCF21 MYL2 MYL2 ADARB1 ADARB1 CAV1 CAV1 WNT2 WNT2 KEL KEL ASB2 ASB2 CAV2 CAV2 HLF HLF NOG NOG SMAD4 SMAD4 MEGF10 MEGF10 PTCD2 PTCD2 LRP2 LRP2 SMAD7 SMAD7 XIRP2 XIRP2 ZFPM2 ZFPM2 RB1 RB1 VAX1 VAX1 SRPK3 SRPK3 HOMER1 HOMER1 BVES BVES POPDC3 POPDC3 HEG1 HEG1 BCL2 BCL2 LOC112406076 LOC112406076 KLHL40 KLHL40 ZBTB18 ZBTB18 LOC112405929 LOC112405929 CDK5 CDK5 CRYAB CRYAB KLF5 KLF5 CUNH9orf24 CUNH9orf24 MYORG MYORG FOXN2 FOXN2 NKX2-5 NKX2-5 LOC112404769 LOC112404769 PITX1 PITX1 EGR1 EGR1 LOC112404312 LOC112404312 USP2 USP2 BCL9L BCL9L PROX1 PROX1 BTG2 BTG2 RIPOR2 RIPOR2 LOC112404062 LOC112404062 MYL3 MYL3 ATF3 ATF3 S1PR1 S1PR1 SAP30 SAP30 SVIL SVIL MYOG MYOG LOC112402910 LOC112402910 TBX20 TBX20 FOXL2 FOXL2 LOC112402911 LOC112402911 HLX HLX DISP1 DISP1 ALX4 ALX4 MYBPC3 MYBPC3 LAMA5 LAMA5 CACNA1S CACNA1S LOC112402372 LOC112402372 KMT5B KMT5B TNNT2 TNNT2 TNNI1 TNNI1 MEF2D MEF2D SIX4 SIX4 CNTF CNTF SMTNL1 SMTNL1 SIX1 SIX1 LMOD3 LMOD3 SGCB SGCB BIN3 BIN3 PKP2 PKP2 WNT5A WNT5A TNNC1 TNNC1 KY KY ELN ELN JPH2 JPH2 MYL10 MYL10 DLL1 DLL1 HIVEP3 HIVEP3 MKL2 MKL2 MYLPF MYLPF NUPR1 NUPR1 ZNF689 ZNF689 PRR14 PRR14 ACTA2 ACTA2 ZNF764 ZNF764 VAMP5 VAMP5 TRIM72 TRIM72 SMYD1 SMYD1 CHD7 CHD7 TMEM182 TMEM182 TCF15 TCF15 LOC112398091 LOC112398091 TCAP TCAP MYLK2 MYLK2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC112397760Emerin-like. (176 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
NR2F2COUP transcription factor 2 isoform X1. (281 aa)
PHOX2BPaired mesoderm homeobox protein 2B. (262 aa)
MYOZ2Myozenin-2. (264 aa)
MYOD1Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (319 aa)
HOXD10Homeobox protein Hox-D10. (410 aa)
KRASGTPase KRas isoform X3. (227 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa)
COL3A1Collagen alpha-1(III) chain. (1463 aa)
NPHS1Nephrin isoform X1. (1275 aa)
CHRNA1Acetylcholine receptor subunit alpha. (457 aa)
ACTC1Actin, alpha cardiac muscle 1. (377 aa)
MEF2CMyocyte-specific enhancer factor 2C isoform X4. (483 aa)
HOXD9Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (282 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (438 aa)
CAVIN4Caveolae-associated protein 4. (362 aa)
ZFPM1Zinc finger protein ZFPM1. (998 aa)
LBX1Transcription factor LBX1. (281 aa)
EDNRAEndothelin-1 receptor isoform X1; Belongs to the G-protein coupled receptor 1 family. (427 aa)
STAC3SH3 and cysteine-rich domain-containing protein 3 isoform X1. (360 aa)
NF1Neurofibromin isoform X1. (2841 aa)
PPP3CASerine/threonine-protein phosphatase. (511 aa)
MYL6Myosin light polypeptide 6 isoform X2. (151 aa)
NR4A1Nuclear receptor subfamily 4 group A member 1. (593 aa)
COPRSCoordinator of PRMT5 and differentiation stimulator. (173 aa)
MYF6Myogenic factor 6. (241 aa)
CHKBCholine/ethanolamine kinase isoform X1. (395 aa)
R3HDM2R3H domain-containing protein 2 isoform X1. (1031 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
MYF5Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (255 aa)
RHOATransforming protein RhoA. (193 aa)
EP300Histone acetyltransferase p300. (2399 aa)
DAG1Dystroglycan. (895 aa)
BMP10Bone morphogenetic protein 10. (423 aa)
MSCMusculin. (198 aa)
SHHSonic hedgehog protein. (328 aa)
HEYLHairy/enhancer-of-split related with YRPW motif-like protein isoform X1. (357 aa)
ACTN1Alpha-actinin-1 isoform X1. (926 aa)
DSPDesmoplakin isoform X1. (2874 aa)
SPG11Spatacsin isoform X1. (2445 aa)
SHOX2Short stature homeobox protein 2 isoform X1. (333 aa)
ISL1Insulin gene enhancer protein ISL-1. (349 aa)
DMRTA2LOW QUALITY PROTEIN: doublesex- and mab-3-related transcription factor A2. (533 aa)
DNERDelta and Notch-like epidermal growth factor-related receptor. (709 aa)
CHRNDAcetylcholine receptor subunit delta isoform X1. (517 aa)
CITED2Cbp/p300-interacting transactivator 2. (263 aa)
ANKRD1Ankyrin repeat domain-containing protein 1. (319 aa)
PPP3CBSerine/threonine-protein phosphatase. (480 aa)
P2RX2P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (479 aa)
PLECLOW QUALITY PROTEIN: plectin. (4609 aa)
CDONCell adhesion molecule-related/down-regulated by oncogenes. (1279 aa)
MTM1Myotubularin isoform X1. (603 aa)
FOXH1Forkhead box protein H1. (360 aa)
MYOZ1Myozenin-1. (298 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1579 aa)
EID2EP300-interacting inhibitor of differentiation 2. (195 aa)
UNC45BProtein unc-45 homolog B isoform X2. (931 aa)
XBP1LOW QUALITY PROTEIN: X-box-binding protein 1. (379 aa)
LIFLeukemia inhibitory factor. (202 aa)
MYH14Myosin-14 isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2008 aa)
VRK3Inactive serine/threonine-protein kinase VRK3. (435 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa)
FXR1Fragile X mental retardation syndrome-related protein 1 isoform X1. (650 aa)
ANKRD33BAnkyrin repeat domain-containing protein 33B. (474 aa)
MEOX2Homeobox protein MOX-2. (303 aa)
SGCEEpsilon-sarcoglycan isoform X1. (473 aa)
ID3DNA-binding protein inhibitor ID-3. (119 aa)
SELENONSelenoprotein N. (564 aa)
EGLN1Egl nine homolog 1. (225 aa)
UNC45AProtein unc-45 homolog A isoform X1. (944 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
MSX1Homeobox protein MSX-1. (303 aa)
LEMD2LEM domain-containing protein 2. (417 aa)
POPDC2Popeye domain-containing protein 2 isoform X1. (370 aa)
METTL8Methyltransferase-like protein; Belongs to the methyltransferase superfamily. METL family. (415 aa)
MYMXProtein myomixer. (84 aa)
JPH1Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (713 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
ACTA1Actin, alpha skeletal muscle. (256 aa)
EGR2E3 SUMO-protein ligase EGR2. (472 aa)
ARID5BAT-rich interactive domain-containing protein 5B isoform X1. (1184 aa)
BMP2Bone morphogenetic protein 2 isoform X1. (395 aa)
CSRP3Cysteine and glycine-rich protein 3 isoform X1. (194 aa)
GPCPD1Glycerophosphocholine phosphodiesterase GPCPD1 isoform X1. (672 aa)
CCNT2cyclin-T2 isoform X1; Belongs to the cyclin family. (742 aa)
R3HDM1R3H domain-containing protein 1 isoform X1. (1053 aa)
DESDesmin; Belongs to the intermediate filament family. (470 aa)
PAX5Paired box protein Pax-5 isoform X1. (391 aa)
NOTCH1LOW QUALITY PROTEIN: neurogenic locus notch homolog protein 1. (2633 aa)
ENGEndoglin. (652 aa)
SMOSmoothened homolog; Belongs to the G-protein coupled receptor Fz/Smo family. (783 aa)
GTF3C5General transcription factor 3C polypeptide 5 isoform X1. (555 aa)
CFL2Cofilin-2; Belongs to the actin-binding proteins ADF family. (149 aa)
STRA6Receptor for retinol uptake STRA6. (668 aa)
MAFFTranscription factor MafF. (166 aa)
KLHL41Kelch-like protein 41. (606 aa)
RYR2Ryanodine receptor 2. (4971 aa)
HAND1Heart- and neural crest derivatives-expressed protein 1. (218 aa)
MKXHomeobox protein Mohawk. (347 aa)
FRG1Protein FRG1. (258 aa)
FZD2Frizzled-2; Belongs to the G-protein coupled receptor Fz/Smo family. (709 aa)
PSIP1PC4 and SFRS1-interacting protein isoform X1. (530 aa)
DMDDystrophin. (2341 aa)
POU4F1POU domain protein. (320 aa)
GSCHomeobox protein goosecoid. (256 aa)
SOX8Transcription factor SOX-8. (378 aa)
FHL1Four and a half LIM domains protein 1 isoform X1. (339 aa)
ZBTB42Zinc finger and BTB domain-containing protein 42. (423 aa)
HEY2Hairy/enhancer-of-split related with YRPW motif protein 2. (337 aa)
TCF21Transcription factor 21. (179 aa)
MYL2Myosin regulatory light chain 2, ventricular/cardiac muscle isoform. (166 aa)
ADARB1Double-stranded RNA-specific editase 1. (701 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
KELKell blood group glycoprotein isoform X1. (793 aa)
ASB2Ankyrin repeat and SOCS box protein 2. (600 aa)
CAV2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (162 aa)
HLFHepatic leukemia factor isoform X1. (296 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
SMAD4Mothers against decapentaplegic homolog. (599 aa)
MEGF10Multiple epidermal growth factor-like domains protein 10. (1138 aa)
PTCD2LOW QUALITY PROTEIN: pentatricopeptide repeat-containing protein 2, mitochondrial. (384 aa)
LRP2Low-density lipoprotein receptor-related protein 2 isoform X1. (4651 aa)
SMAD7Mothers against decapentaplegic homolog. (426 aa)
XIRP2Xin actin-binding repeat-containing protein 2 isoform X1. (3323 aa)
ZFPM2Zinc finger protein ZFPM2. (1150 aa)
RB1Retinoblastoma-associated protein. (816 aa)
VAX1Ventral anterior homeobox 1. (156 aa)
SRPK3SRSF protein kinase 3. (599 aa)
HOMER1Homer protein homolog 1 isoform X1. (354 aa)
BVESBlood vessel epicardial substance. (360 aa)
POPDC3Popeye domain-containing protein 3. (291 aa)
HEG1Protein HEG homolog 1. (1138 aa)
BCL2Apoptosis regulator Bcl-2 isoform X1. (233 aa)
LOC112406076Protein HEG homolog 1-like. (419 aa)
KLHL40Kelch-like protein 40. (623 aa)
ZBTB18Zinc finger and BTB domain-containing protein 18 isoform X1. (535 aa)
LOC112405929Collagen alpha-1(XIX) chain-like. (427 aa)
CDK5Cyclin-dependent-like kinase 5; Belongs to the protein kinase superfamily. (292 aa)
CRYABAlpha-crystallin B chain; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. (175 aa)
KLF5Krueppel-like factor 5. (454 aa)
CUNH9orf24Spermatid-specific manchette-related protein 1. (260 aa)
MYORGMyogenesis-regulating glycosidase; Belongs to the glycosyl hydrolase 31 family. (714 aa)
FOXN2Forkhead box protein N2. (439 aa)
NKX2-5Homeobox protein Nkx-2.5. (323 aa)
LOC112404769Dystrophin-like. (245 aa)
PITX1Homeobox protein. (435 aa)
EGR1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (531 aa)
LOC112404312Collagen alpha-1(XIX) chain-like. (473 aa)
USP2Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (603 aa)
BCL9LB-cell CLL/lymphoma 9-like protein isoform X1. (1493 aa)
PROX1Prospero homeobox protein 1 isoform X1. (737 aa)
BTG2Protein BTG2. (162 aa)
RIPOR2Rho family-interacting cell polarization regulator 2 isoform X6. (1097 aa)
LOC112404062Dystrophin-like. (160 aa)
MYL3Myosin light chain 3. (197 aa)
ATF3Cyclic AMP-dependent transcription factor ATF-3. (181 aa)
S1PR1Sphingosine 1-phosphate receptor 1; Belongs to the G-protein coupled receptor 1 family. (382 aa)
SAP30Histone deacetylase complex subunit SAP30. (119 aa)
SVILSupervillin isoform X1. (1746 aa)
MYOGMyogenin. (224 aa)
LOC112402910Supervillin-like. (151 aa)
TBX20T-box transcription factor TBX20. (449 aa)
FOXL2LOW QUALITY PROTEIN: forkhead box protein L2. (191 aa)
LOC112402911Supervillin-like. (98 aa)
HLXH2.0-like homeobox protein. (486 aa)
DISP1Protein dispatched homolog 1 isoform X1. (1565 aa)
ALX4Homeobox protein aristaless-like 4. (408 aa)
MYBPC3Myosin-binding protein C, cardiac-type. (1277 aa)
LAMA5LOW QUALITY PROTEIN: laminin subunit alpha-5. (3401 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1866 aa)
LOC112402372Actin-1-like; Belongs to the actin family. (172 aa)
KMT5BHistone-lysine N-methyltransferase KMT5B isoform X1. (883 aa)
TNNT2Troponin T, cardiac muscle isoform X1. (333 aa)
TNNI1Troponin I, slow skeletal muscle. (166 aa)
MEF2DMyocyte-specific enhancer factor 2D. (504 aa)
SIX4Homeobox protein SIX4. (793 aa)
CNTFCiliary neurotrophic factor. (200 aa)
SMTNL1Smoothelin-like protein 1. (574 aa)
SIX1Homeobox protein SIX1. (284 aa)
LMOD3Leiomodin-3. (564 aa)
SGCBBeta-sarcoglycan. (586 aa)
BIN3Bridging integrator 3 isoform X1. (253 aa)
PKP2Plakophilin-2. (826 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
TNNC1Troponin C, slow skeletal and cardiac muscles. (161 aa)
KYKyphoscoliosis peptidase isoform X1. (661 aa)
ELNElastin isoform X1. (744 aa)
JPH2LOW QUALITY PROTEIN: junctophilin-2. (502 aa)
MYL10Myosin regulatory light chain 10. (147 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (759 aa)
HIVEP3Transcription factor HIVEP3 isoform X1. (2401 aa)
MKL2MKL/myocardin-like protein 2. (1076 aa)
MYLPFMyosin regulatory light chain 2, skeletal muscle isoform. (170 aa)
NUPR1Nuclear protein 1. (82 aa)
ZNF689Zinc finger protein 689. (985 aa)
PRR14Proline-rich protein 14 isoform X1. (588 aa)
ACTA2Actin, aortic smooth muscle. (377 aa)
ZNF764Zinc finger protein 764 isoform X1. (408 aa)
VAMP5Vesicle-associated membrane protein 5. (116 aa)
TRIM72Tripartite motif-containing protein 72. (519 aa)
SMYD1Histone-lysine N-methyltransferase SMYD1 isoform X1. (490 aa)
CHD7LOW QUALITY PROTEIN: chromodomain-helicase-DNA-binding protein 7. (3000 aa)
TMEM182Transmembrane protein 182 isoform X1. (229 aa)
TCF15Transcription factor 15. (229 aa)
LOC112398091Dystrophin-like. (216 aa)
TCAPTelethonin isoform X1. (167 aa)
MYLK2Myosin light chain kinase 2, skeletal/cardiac muscle. (615 aa)
Your Current Organism:
Neophocaena asiaeorientalis
NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise
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