STRINGSTRING
CIB1 CIB1 CDC42 CDC42 COL16A1 COL16A1 AGR2 AGR2 CDK6 CDK6 BCL6 BCL6 NEXMIF NEXMIF HRG HRG PTK2B PTK2B EMID1 EMID1 CALR CALR CYR61 CYR61 ANGPT2 ANGPT2 FUT1 FUT1 RRAS RRAS GSK3B GSK3B FERMT2 FERMT2 SLK SLK RASA1 RASA1 FOXF1 FOXF1 CRK CRK JAG1 JAG1 CORO2A CORO2A C1QBP C1QBP EDIL3 EDIL3 KANK1 KANK1 GREM1 GREM1 ACTN4 ACTN4 FMN1 FMN1 THBS1 THBS1 ECM2 ECM2 LIMCH1 LIMCH1 LDB1 LDB1 PHLDB2 PHLDB2 CCDC80 CCDC80 NF1 NF1 ACVRL1 ACVRL1 CDH13 CDH13 WNT1 WNT1 VTN VTN FBLN1 FBLN1 MYF5 MYF5 ITGB1BP1 ITGB1BP1 ALOX15 ALOX15 LIMS2 LIMS2 RHOA RHOA SEMA3E SEMA3E MACF1 MACF1 RREB1 RREB1 DDR1 DDR1 SPOCK2 SPOCK2 CCL28 CCL28 MYOC MYOC LOC112395837 LOC112395837 AP1AR AP1AR CORO1C CORO1C VCL VCL PLAU PLAU BST1 BST1 FLNA FLNA CSF1 CSF1 PTPRA PTPRA BRAF BRAF EFNA5 EFNA5 MYADM MYADM SPOCK3 SPOCK3 EMP2 EMP2 COL1A1 COL1A1 CAMSAP3 CAMSAP3 COL26A1 COL26A1 JUP JUP STK4 STK4 SKAP1 SKAP1 CORO2B CORO2B GCNT2 GCNT2 DOCK5 DOCK5 KDR KDR DMTN DMTN ACER2 ACER2 UTRN UTRN PLG PLG PTPRJ PTPRJ HSD17B12 HSD17B12 EFEMP2 EFEMP2 ADAM15 ADAM15 RCC2 RCC2 RSU1 RSU1 ARL2 ARL2 PREX1 PREX1 PDPN PDPN PIK3CB PIK3CB CASS4 CASS4 CARMIL1 CARMIL1 THY1 THY1 APOA1 APOA1 RELL2 RELL2 SPRY4 SPRY4 MELTF MELTF WDPCP WDPCP APOD APOD PIK3R1 PIK3R1 SPOCK1 SPOCK1 VIT VIT PRKCE PRKCE CCL21 CCL21 NPNT NPNT RIN2 RIN2 PLET1 PLET1 ONECUT1 ONECUT1 EGFLAM EGFLAM TEK TEK ONECUT2 ONECUT2 BCL2 BCL2 HOXA7 HOXA7 TACSTD2 TACSTD2 ILK ILK LOC112408148 LOC112408148 ARHGAP6 ARHGAP6 LIMS1 LIMS1 ROCK1 ROCK1 FZD7 FZD7 LOC112408488 LOC112408488 EPHA1 EPHA1 EPB41L5 EPB41L5 COL8A1 COL8A1 ABI3BP ABI3BP CASK CASK AJAP1 AJAP1 TBCD TBCD ITGB3 ITGB3 LOC112409739 LOC112409739 LRRC45 LRRC45 P4HB P4HB EPHA3 EPHA3 NID1 NID1 PDGFB PDGFB ACTG1 ACTG1 RAC2 RAC2 UNC13D UNC13D PEAK1 PEAK1 LOC112410791 LOC112410791 ABL1 ABL1 LOC112410823 LOC112410823 TSC1 TSC1 NOTCH1 NOTCH1 S100A10 S100A10 TESK1 TESK1 FN1 FN1 FBLN2 FBLN2 NEDD9 NEDD9 PPM1F PPM1F FZD4 FZD4 CRKL CRKL VWC2 VWC2 EMILIN1 EMILIN1 SFRP1 SFRP1 FERMT1 FERMT1 DLC1 DLC1 NRP1 NRP1 PLEKHA2 PLEKHA2 VEGFA VEGFA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CIB1Calcium and integrin-binding protein 1. (191 aa)
CDC42Cell division control protein 42 homolog. (191 aa)
COL16A1Collagen alpha-1(XVI) chain isoform X1. (1632 aa)
AGR2Anterior gradient protein 2 homolog. (175 aa)
CDK6Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa)
BCL6B-cell lymphoma 6 protein. (706 aa)
NEXMIFNeurite extension and migration factor. (1515 aa)
HRGLOW QUALITY PROTEIN: histidine-rich glycoprotein. (427 aa)
PTK2BProtein-tyrosine kinase 2-beta isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
EMID1EMI domain-containing protein 1 isoform X1. (458 aa)
CALRCalreticulin. (417 aa)
CYR61Protein CYR61. (382 aa)
ANGPT2Angiopoietin-2 isoform X1. (496 aa)
FUT1L-Fucosyltransferase; Belongs to the glycosyltransferase 11 family. (532 aa)
RRASRas-related protein R-Ras. (209 aa)
GSK3BGlycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily. (433 aa)
FERMT2Fermitin family homolog 2. (680 aa)
SLKSTE20-like serine/threonine-protein kinase isoform X1. (1240 aa)
RASA1Ras GTPase-activating protein 1. (1040 aa)
FOXF1Forkhead box protein F1. (375 aa)
CRKAdapter molecule crk isoform X1. (385 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1177 aa)
CORO2ACoronin; Belongs to the WD repeat coronin family. (525 aa)
C1QBPComplement component 1 Q subcomponent-binding protein, mitochondrial. (278 aa)
EDIL3EGF-like repeat and discoidin I-like domain-containing protein 3 isoform X1. (479 aa)
KANK1KN motif and ankyrin repeat domain-containing protein 1 isoform X1. (1351 aa)
GREM1Gremlin. (184 aa)
ACTN4Alpha-actinin-4 isoform X2. (827 aa)
FMN1Formin-1 isoform X1. (1420 aa)
THBS1Thrombospondin-1. (1170 aa)
ECM2Extracellular matrix protein 2 isoform X1. (695 aa)
LIMCH1LIM and calponin homology domains-containing protein 1 isoform X1. (1629 aa)
LDB1LIM domain-binding protein 1 isoform X1. (411 aa)
PHLDB2Pleckstrin homology-like domain family B member 2 isoform X1. (1261 aa)
CCDC80Coiled-coil domain-containing protein 80. (951 aa)
NF1Neurofibromin isoform X1. (2841 aa)
ACVRL1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (515 aa)
CDH13Cadherin-13. (713 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
VTNVitronectin. (481 aa)
FBLN1Fibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes. (693 aa)
MYF5Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (255 aa)
ITGB1BP1Integrin beta-1-binding protein 1 isoform X1. (206 aa)
ALOX15LOW QUALITY PROTEIN: arachidonate 15-lipoxygenase. (663 aa)
LIMS2LIM and senescent cell antigen-like-containing domain protein; Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. (336 aa)
RHOATransforming protein RhoA. (193 aa)
SEMA3Esemaphorin-3E; Belongs to the semaphorin family. (715 aa)
MACF1Microtubule-actin cross-linking factor 1 isoform X1. (7492 aa)
RREB1Ras-responsive element-binding protein 1. (1784 aa)
DDR1Tyrosine-protein kinase receptor. (932 aa)
SPOCK2Testican-2 isoform X1. (423 aa)
CCL28C-C motif chemokine. (127 aa)
MYOCMyocilin isoform X1. (474 aa)
LOC112395837LOW QUALITY PROTEIN: calreticulin-like. (540 aa)
AP1ARAP-1 complex-associated regulatory protein isoform X1. (302 aa)
CORO1CCoronin; Belongs to the WD repeat coronin family. (474 aa)
VCLVinculin isoform X2. (1134 aa)
PLAUUrokinase-type plasminogen activator. (431 aa)
BST1ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 isoform X1. (357 aa)
FLNAfilamin-A isoform X1. (2592 aa)
CSF1Macrophage colony-stimulating factor 1. (513 aa)
PTPRAReceptor-type tyrosine-protein phosphatase alpha. (802 aa)
BRAFSerine/threonine-protein kinase B-raf isoform X1. (581 aa)
EFNA5ephrin-A5 isoform X1; Belongs to the ephrin family. (228 aa)
MYADMMyeloid-associated differentiation marker. (320 aa)
SPOCK3Testican-3. (314 aa)
EMP2Epithelial membrane protein 2; Functions as a key regulator of cell membrane composition by regulating proteins surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion; Belongs to the PMP-22/EMP/MP20 family. (167 aa)
COL1A1Collagen alpha-1(I) chain. (1463 aa)
CAMSAP3Calmodulin-regulated spectrin-associated protein 3. (1166 aa)
COL26A1Collagen alpha-1(XXVI) chain. (425 aa)
JUPJunction plakoglobin. (744 aa)
STK4Serine/threonine-protein kinase 4 isoform X1. (487 aa)
SKAP1Src kinase-associated phosphoprotein 1. (324 aa)
CORO2BCoronin; Belongs to the WD repeat coronin family. (475 aa)
GCNT2N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase isoform X1. (419 aa)
DOCK5Dedicator of cytokinesis protein 5 isoform X1; Belongs to the DOCK family. (1864 aa)
KDRVascular endothelial growth factor receptor 2 isoform X4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
DMTNDematin isoform X1. (405 aa)
ACER2Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (275 aa)
UTRNUtrophin isoform X1. (3439 aa)
PLGPlasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] (814 aa)
PTPRJReceptor-type tyrosine-protein phosphatase eta isoform X1. (1273 aa)
HSD17B12Very-long-chain 3-oxoacyl-CoA reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (280 aa)
EFEMP2EGF-containing fibulin-like extracellular matrix protein 2. (449 aa)
ADAM15Disintegrin and metalloproteinase domain-containing protein 15 isoform X1. (866 aa)
RCC2Protein RCC2. (469 aa)
RSU1Ras suppressor protein 1 isoform X1. (277 aa)
ARL2ADP-ribosylation factor-like protein 2; Belongs to the small GTPase superfamily. Arf family. (184 aa)
PREX1Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein isoform X1. (1674 aa)
PDPNPodoplanin isoform X1. (234 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1064 aa)
CASS4Cas scaffolding protein family member 4 isoform X1. (821 aa)
CARMIL1F-actin-uncapping protein LRRC16A isoform X1. (1422 aa)
THY1Thy-1 membrane glycoprotein. (161 aa)
APOA1Apolipoprotein A-I. (265 aa)
RELL2RELT-like protein 2 isoform X1. (303 aa)
SPRY4Protein sprouty homolog 4. (299 aa)
MELTFMelanotransferrin. (873 aa)
WDPCPWD repeat-containing and planar cell polarity effector protein fritz homolog. (639 aa)
APODApolipoprotein D isoform X1; Belongs to the calycin superfamily. Lipocalin family. (243 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
SPOCK1Testican-1 isoform X1. (442 aa)
VITVitrin. (652 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (737 aa)
CCL21C-C motif chemokine 21 isoform X1. (131 aa)
NPNTNephronectin isoform X1. (581 aa)
RIN2Ras and Rab interactor 2. (827 aa)
PLET1Placenta-expressed transcript 1 protein. (326 aa)
ONECUT1One cut domain family member. (465 aa)
EGFLAMPikachurin. (1018 aa)
TEKAngiopoietin-1 receptor isoform X1. (1125 aa)
ONECUT2One cut domain family member. (367 aa)
BCL2Apoptosis regulator Bcl-2 isoform X1. (233 aa)
HOXA7Homeobox protein Hox-A7. (233 aa)
TACSTD2Tumor-associated calcium signal transducer 2. (419 aa)
ILKIntegrin-linked protein kinase isoform X1. (485 aa)
LOC112408148LOW QUALITY PROTEIN: tumor-associated calcium signal transducer 2-like. (329 aa)
ARHGAP6Rho GTPase-activating protein 6 isoform X1. (777 aa)
LIMS1LIM and senescent cell antigen-like-containing domain protein; Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. (397 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1354 aa)
FZD7Frizzled-7; Belongs to the G-protein coupled receptor Fz/Smo family. (574 aa)
LOC112408488Serine/threonine-protein kinase B-raf-like. (250 aa)
EPHA1Ephrin type-A receptor 1 isoform X1. (981 aa)
EPB41L5Band 4.1-like protein 5 isoform X1. (746 aa)
COL8A1Collagen alpha-1(VIII) chain. (744 aa)
ABI3BPTarget of Nesh-SH3 isoform X2. (1714 aa)
CASKPeripheral plasma membrane protein CASK isoform X1; Belongs to the MAGUK family. (920 aa)
AJAP1Adherens junction-associated protein 1. (399 aa)
TBCDTubulin-specific chaperone D. (1197 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (789 aa)
LOC112409739LOW QUALITY PROTEIN: uncharacterized protein LOC112409739. (505 aa)
LRRC45Leucine-rich repeat-containing protein 45 isoform X1. (670 aa)
P4HBProtein disulfide-isomerase. (510 aa)
EPHA3Ephrin type-A receptor 3 isoform X1. (984 aa)
NID1Nidogen-1 isoform X1. (1242 aa)
PDGFBPlatelet-derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (209 aa)
ACTG1Actin, cytoplasmic 2. (375 aa)
RAC2Ras-related C3 botulinum toxin substrate 2. (197 aa)
UNC13DProtein unc-13 homolog D isoform X1. (1120 aa)
PEAK1Pseudopodium-enriched atypical kinase 1. (1745 aa)
LOC112410791TRIO and F-actin-binding protein-like. (1009 aa)
ABL1Tyrosine-protein kinase. (1148 aa)
LOC112410823TRIO and F-actin-binding protein-like isoform X1. (608 aa)
TSC1Hamartin isoform X1. (1169 aa)
NOTCH1LOW QUALITY PROTEIN: neurogenic locus notch homolog protein 1. (2633 aa)
S100A10Protein S100-A10; Belongs to the S-100 family. (97 aa)
TESK1Dual specificity testis-specific protein kinase 1 isoform X1. (546 aa)
FN1Fibronectin isoform X5. (2478 aa)
FBLN2Fibulin-2 isoform X1. (1217 aa)
NEDD9Enhancer of filamentation 1 isoform X2. (829 aa)
PPM1FProtein phosphatase 1F isoform X1. (433 aa)
FZD4Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa)
CRKLCrk-like protein. (303 aa)
VWC2LOW QUALITY PROTEIN: brorin. (304 aa)
EMILIN1EMILIN-1. (1015 aa)
SFRP1Secreted frizzled-related protein 1. (296 aa)
FERMT1Fermitin family homolog 1 isoform X1. (677 aa)
DLC1Rho GTPase-activating protein 7 isoform X1. (1528 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (924 aa)
PLEKHA2Pleckstrin homology domain-containing family A member 2 isoform X1. (425 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (632 aa)
Your Current Organism:
Neophocaena asiaeorientalis
NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise
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