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INPP5K INPP5K FABP5 FABP5 APPL2 APPL2 LOC112414965 LOC112414965 GSK3A GSK3A GRB10 GRB10 LEP LEP ENPP1 ENPP1 PEA15 PEA15 PRKCB PRKCB STXBP3 STXBP3 OSTN OSTN PID1 PID1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
INPP5KInositol polyphosphate 5-phosphatase K isoform X3. (476 aa)
FABP5Fatty acid-binding protein, epidermal; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (135 aa)
APPL2DCC-interacting protein 13-beta isoform X1. (661 aa)
LOC112414965LOW QUALITY PROTEIN: growth factor receptor-bound protein 10-like. (543 aa)
GSK3AGlycogen synthase kinase-3 alpha. (320 aa)
GRB10Growth factor receptor-bound protein 10. (588 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
ENPP1Ectonucleotide pyrophosphatase/phosphodiesterase family member 1. (857 aa)
PEA15Astrocytic phosphoprotein PEA-15. (130 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
STXBP3Syntaxin-binding protein 3; Belongs to the STXBP/unc-18/SEC1 family. (592 aa)
OSTNOsteocrin. (132 aa)
PID1PTB-containing, cubilin and LRP1-interacting protein isoform X1. (217 aa)
Your Current Organism:
Neophocaena asiaeorientalis
NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise
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