STRINGSTRING
AKT2 AKT2 SIRT1 SIRT1 PTPN2 PTPN2 WDR5 WDR5 AKT1 AKT1 PTH PTH EPM2AIP1 EPM2AIP1 INMT INMT FOXO1 FOXO1 PMAIP1 PMAIP1 IRS2 IRS2 LOC112404007 LOC112404007 GPLD1 GPLD1 SLC45A3 SLC45A3 INS INS ACTN3 ACTN3 DDB1 DDB1 GCK GCK LOC112401115 LOC112401115 INSR INSR KAT2A KAT2A KAT2B KAT2B IRS1 IRS1 PPARA PPARA DYRK2 DYRK2 GCG GCG LOC112392089 LOC112392089 IGF1 IGF1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
SIRT1NAD-dependent protein deacetylase sirtuin-1 isoform X1. (557 aa)
PTPN2Tyrosine-protein phosphatase non-receptor type. (396 aa)
WDR5WD repeat-containing protein 5. (334 aa)
AKT1RAC-alpha serine/threonine-protein kinase; Belongs to the protein kinase superfamily. (339 aa)
PTHParathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family. (119 aa)
EPM2AIP1EPM2A-interacting protein 1. (608 aa)
INMTLOW QUALITY PROTEIN: indolethylamine N-methyltransferase. (295 aa)
FOXO1Forkhead box protein O1. (511 aa)
PMAIP1Phorbol-12-myristate-13-acetate-induced protein 1. (54 aa)
IRS2Insulin receptor substrate 2. (702 aa)
LOC112404007Nicotinamide N-methyltransferase. (264 aa)
GPLD1Phosphatidylinositol-glycan-specific phospholipase D. (849 aa)
SLC45A3Solute carrier family 45 member 3. (553 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
ACTN3Alpha-actinin-3. (902 aa)
DDB1DNA damage-binding protein 1. (1140 aa)
GCKPhosphotransferase. (537 aa)
LOC112401115General transcription factor II-I repeat domain-containing protein 2. (948 aa)
INSRTyrosine-protein kinase receptor. (1382 aa)
KAT2AHistone acetyltransferase KAT2A. (872 aa)
KAT2BHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (823 aa)
IRS1Insulin receptor substrate 1. (1248 aa)
PPARAPeroxisome proliferator-activated receptor alpha. (468 aa)
DYRK2Dual specificity tyrosine-phosphorylation-regulated kinase 2 isoform X1. (537 aa)
GCGGlucagon isoform X1. (180 aa)
LOC112392089RAC-alpha serine/threonine-protein kinase. (138 aa)
IGF1Insulin-like growth factor I isoform X1. (208 aa)
Your Current Organism:
Neophocaena asiaeorientalis
NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise
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