STRINGSTRING
F2RL3 F2RL3 HRG HRG COMP COMP BLOC1S3 BLOC1S3 AXL AXL RAP2B RAP2B P2RY12 P2RY12 FN1 FN1 GATA1 GATA1 ENTPD2 ENTPD2 ITGB3 ITGB3 GNA13 GNA13 CD40LG CD40LG ADRA2A ADRA2A PPBP PPBP LOC112405696 LOC112405696 F2 F2 TSPAN32 TSPAN32 PEAR1 PEAR1 FERMT3 FERMT3 PDGFRA PDGFRA BLOC1S4 BLOC1S4 SLC7A11 SLC7A11 ADRA2C ADRA2C FZD6 FZD6 ADRA2B ADRA2B MERTK MERTK STXBP3 STXBP3 PLEK PLEK UBASH3B UBASH3B RAP2A RAP2A LOC112392054 LOC112392054 PTPN6 PTPN6 P2RX1 P2RX1 VWF VWF F2R F2R FGA FGA TYRO3 TYRO3 FGB FGB FGG FGG STXBP1 STXBP1 SERPINE2 SERPINE2 WNT3A WNT3A TREML1 TREML1 SRF SRF
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
F2RL3Proteinase-activated receptor 4; Belongs to the G-protein coupled receptor 1 family. (380 aa)
HRGLOW QUALITY PROTEIN: histidine-rich glycoprotein. (427 aa)
COMPCartilage oligomeric matrix protein. (756 aa)
BLOC1S3Biogenesis of lysosome-related organelles complex 1 subunit 3. (148 aa)
AXLTyrosine-protein kinase receptor UFO. (887 aa)
RAP2BRas-related protein Rap-2b. (183 aa)
P2RY12P2Y purinoceptor 12. (339 aa)
FN1Fibronectin isoform X5. (2478 aa)
GATA1Erythroid transcription factor. (413 aa)
ENTPD2Ectonucleoside triphosphate diphosphohydrolase 2 isoform X2; Belongs to the GDA1/CD39 NTPase family. (588 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (789 aa)
GNA13Guanine nucleotide-binding protein subunit alpha-13. (282 aa)
CD40LGCD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. (261 aa)
ADRA2ALOW QUALITY PROTEIN: alpha-2A adrenergic receptor. (430 aa)
PPBPC-X-C motif chemokine. (119 aa)
LOC112405696C-X-C motif chemokine. (112 aa)
F2Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (623 aa)
TSPAN32Tetraspanin-32; Belongs to the tetraspanin (TM4SF) family. (329 aa)
PEAR1Platelet endothelial aggregation receptor 1 isoform X1. (1041 aa)
FERMT3Fermitin family homolog 3. (663 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa)
BLOC1S4Biogenesis of lysosome-related organelles complex 1 subunit 4. (264 aa)
SLC7A11Cystine/glutamate transporter isoform X1. (615 aa)
ADRA2Calpha-2C adrenergic receptor. (518 aa)
FZD6Frizzled-6; Belongs to the G-protein coupled receptor Fz/Smo family. (712 aa)
ADRA2Balpha-2B adrenergic receptor isoform X1. (447 aa)
MERTKTyrosine-protein kinase Mer. (999 aa)
STXBP3Syntaxin-binding protein 3; Belongs to the STXBP/unc-18/SEC1 family. (592 aa)
PLEKPleckstrin. (350 aa)
UBASH3BUbiquitin-associated and SH3 domain-containing protein B isoform X1. (649 aa)
RAP2ARas-related protein Rap-2a isoform X1. (183 aa)
LOC112392054Fibrinogen alpha chain-like. (460 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (595 aa)
P2RX1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (512 aa)
VWFVon Willebrand factor. (2804 aa)
F2RProteinase-activated receptor 1; Belongs to the G-protein coupled receptor 1 family. (427 aa)
FGAFibrinogen alpha chain. (407 aa)
TYRO3Tyrosine-protein kinase receptor TYRO3. (822 aa)
FGBFibrinogen beta chain isoform X1. (495 aa)
FGGFibrinogen gamma chain isoform X1. (445 aa)
STXBP1Syntaxin-binding protein 1 isoform X1; Belongs to the STXBP/unc-18/SEC1 family. (580 aa)
SERPINE2Glia-derived nexin; Belongs to the serpin family. (397 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
TREML1Trem-like transcript 1 protein isoform X1. (315 aa)
SRFSerum response factor isoform X1. (535 aa)
Your Current Organism:
Neophocaena asiaeorientalis
NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise
Server load: low (18%) [HD]