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| | STAT6 | Signal transducer and activator of transcription. (859 aa) |
| | ADA | Adenosine deaminase isoform X1. (402 aa) |
| | IL6R | Interleukin-6 receptor subunit alpha. (465 aa) |
| | ZBTB7B | Zinc finger and BTB domain-containing protein 7B. (542 aa) |
| | IRF1 | Interferon regulatory factor. (322 aa) |
| | GBA | Glucosylceramidase. (568 aa) |
| | TCIRG1 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (589 aa) |
| | SEMA4A | semaphorin-4A isoform X1; Belongs to the semaphorin family. (762 aa) |
| | LOC112402169 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (259 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2548 aa) |
| | FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (211 aa) |
| | PREX1 | Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein isoform X1. (1674 aa) |
| | HLX | H2.0-like homeobox protein. (486 aa) |
| | ZBTB1 | Zinc finger and BTB domain-containing protein 1. (713 aa) |
| | SOX13 | Transcription factor SOX-13. (592 aa) |
| | PAX1 | LOW QUALITY PROTEIN: paired box protein Pax-1. (445 aa) |
| | SLAMF6 | SLAM family member 6 isoform X1. (351 aa) |
| | CD3E | T-cell surface glycoprotein CD3 epsilon chain. (195 aa) |
| | CD3D | T-cell surface glycoprotein CD3 delta chain isoform X1. (171 aa) |
| | IL7 | Interleukin-7 isoform X1. (226 aa) |
| | CCR9 | C-C chemokine receptor type 9 isoform X1; Belongs to the G-protein coupled receptor 1 family. (369 aa) |
| | RAG2 | V(D)J recombination-activating protein 2. (527 aa) |
| | EGR1 | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (531 aa) |
| | RAG1 | V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (1043 aa) |
| | DOCK2 | Dedicator of cytokinesis protein 2; Belongs to the DOCK family. (1827 aa) |
| | EOMES | LOW QUALITY PROTEIN: eomesodermin homolog. (703 aa) |
| | BCL6 | B-cell lymphoma 6 protein. (706 aa) |
| | ZNF683 | LOW QUALITY PROTEIN: tissue-resident T-cell transcription regulator protein ZNF683. (505 aa) |
| | PATZ1 | POZ-, AT hook-, and zinc finger-containing protein 1 isoform X1. (687 aa) |
| | IL12B | Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (329 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa) |
| | RELB | Transcription factor RelB. (578 aa) |
| | BCL3 | B-cell lymphoma 3 protein. (358 aa) |
| | RABL3 | Rab-like protein 3. (236 aa) |
| | CCR7 | C-C chemokine receptor type 7; Belongs to the G-protein coupled receptor 1 family. (379 aa) |
| | PRR7 | Proline-rich protein 7. (269 aa) |
| | LOC112400322 | C-type lectin domain family 4 member G-like. (290 aa) |
| | CCR6 | C-C chemokine receptor type 6; Belongs to the G-protein coupled receptor 1 family. (375 aa) |
| | FOXP3 | LOW QUALITY PROTEIN: forkhead box protein P3. (452 aa) |
| | VAV1 | Proto-oncogene vav isoform X1. (845 aa) |
| | IL21 | Interleukin; Belongs to the IL-15/IL-21 family. (146 aa) |
| | TCF7 | Transcription factor 7 isoform X1. (303 aa) |
| | STAT3 | Signal transducer and activator of transcription. (770 aa) |
| | LOC112399174 | Signal transducer and activator of transcription. (618 aa) |
| | TBX21 | T-box transcription factor TBX21. (501 aa) |
| | STK11 | Serine/threonine-protein kinase STK11 isoform X1. (546 aa) |
| | GPR18 | N-arachidonyl glycine receptor; Belongs to the G-protein coupled receptor 1 family. (354 aa) |
| | LOC112396133 | G-protein coupled receptor 183; Belongs to the G-protein coupled receptor 1 family. (360 aa) |
| | ITPKB | Kinase; Belongs to the inositol phosphokinase (IPK) family. (939 aa) |
| | FZD5 | Frizzled-5; Belongs to the G-protein coupled receptor Fz/Smo family. (555 aa) |
| | SHH | Sonic hedgehog protein. (328 aa) |
| | IL6 | Interleukin-6. (208 aa) |
| | BATF | Basic leucine zipper transcriptional factor ATF-like. (125 aa) |
| | CD28 | T-cell-specific surface glycoprotein CD28. (265 aa) |
| | NCAPH2 | Condensin-2 complex subunit H2 isoform X1. (612 aa) |
| | RHOA | Transforming protein RhoA. (193 aa) |
| | FOXN1 | Forkhead box protein N1. (645 aa) |
| | RSAD2 | Radical S-adenosyl methionine domain-containing protein 2. (362 aa) |
| | CD8A | T-cell surface glycoprotein CD8 alpha chain isoform X1. (239 aa) |
| | ARMC5 | Armadillo repeat-containing protein 5. (827 aa) |
| | LOC112398972 | Tyrosine-protein kinase. (612 aa) |
| | TOX | Thymocyte selection-associated high mobility group box protein TOX. (478 aa) |
| | IL18R1 | Interleukin-18 receptor 1 isoform X1. (555 aa) |
| | CHD7 | LOW QUALITY PROTEIN: chromodomain-helicase-DNA-binding protein 7. (3000 aa) |
| | ERBB2 | Receptor protein-tyrosine kinase. (1255 aa) |
| | WNT10B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa) |
| | LOC112397886 | LOW QUALITY PROTEIN: butyrophilin-like protein 1. (396 aa) |
| | MAFB | Transcription factor MafB. (323 aa) |
| | BRAF | Serine/threonine-protein kinase B-raf isoform X1. (581 aa) |
| | IKZF3 | Zinc finger protein Aiolos isoform X1. (528 aa) |
| | PSMB11 | Proteasome subunit beta. (291 aa) |
| | TRAF3IP2 | Adapter protein CIKS isoform X1. (564 aa) |
| | LEF1 | Lymphoid enhancer-binding factor 1 isoform X1. (414 aa) |
| | SOX4 | Transcription factor SOX-4. (285 aa) |
| | PPP3CB | Serine/threonine-protein phosphatase. (480 aa) |
| | ZFP36L1 | mRNA decay activator protein ZFP36L1. (338 aa) |
| | ANXA1 | Annexin. (346 aa) |
| | RHOH | Rho-related GTP-binding protein RhoH. (191 aa) |
| | GATA3 | Trans-acting T-cell-specific transcription factor GATA-3 isoform X1. (444 aa) |
| | CD74 | HLA class II histocompatibility antigen gamma chain isoform X1. (278 aa) |
| | SYK | Tyrosine-protein kinase. (626 aa) |
| | LOC112391701 | LOW QUALITY PROTEIN: C-type lectin domain family 4 member D-like. (174 aa) |
| | DLL4 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa) |
| | LOC112391950 | C-type lectin domain family 4 member E-like. (212 aa) |
| | LOC112391354 | Golgi pH regulator isoform X1. (455 aa) |
| | SP3 | Transcription factor Sp3. (1112 aa) |
| | ATF2 | Cyclic AMP-dependent transcription factor ATF-2 isoform X1. (505 aa) |
| | GLI3 | Transcriptional activator GLI3. (1587 aa) |
| | CRACR2A | EF-hand calcium-binding domain-containing protein 4B. (729 aa) |
| | LOC112392034 | Signal transducer and activator of transcription 5A-like. (105 aa) |
| | NKX2-3 | Homeobox protein Nkx-2.3. (363 aa) |
| | ENTPD7 | Ectonucleoside triphosphate diphosphohydrolase 7 isoform X1; Belongs to the GDA1/CD39 NTPase family. (604 aa) |
| | TMEM98 | Transmembrane protein 98. (226 aa) |
| | RORA | Nuclear receptor ROR-alpha. (386 aa) |
| | IL15 | Interleukin; Belongs to the IL-15/IL-21 family. (180 aa) |
| | LMBR1L | Protein LMBR1L isoform X1; Belongs to the LIMR family. (520 aa) |
| | WNT1 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa) |
| | KIT | Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (976 aa) |
| | ZFP36L2 | mRNA decay activator protein ZFP36L2. (492 aa) |
| | CTSL | Cathepsin L1 isoform X1; Belongs to the peptidase C1 family. (333 aa) |
| | LIG4 | DNA ligase. (911 aa) |
| | RIPK3 | LOW QUALITY PROTEIN: receptor-interacting serine/threonine-protein kinase 3. (518 aa) |
| | CTNNB1 | Catenin beta-1. (781 aa) |
| | GIMAP1 | GTPase IMAP family member 1 isoform X1. (332 aa) |
| | PTGER4 | Prostaglandin E2 receptor EP4 subtype; Belongs to the G-protein coupled receptor 1 family. (486 aa) |
| | IL7R | Interleukin-7 receptor subunit alpha. (459 aa) |
| | BCL2 | Apoptosis regulator Bcl-2 isoform X1. (233 aa) |
| | ATG5 | Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa) |
| | RIPK2 | Receptor-interacting serine/threonine-protein kinase 2. (387 aa) |
| | FCER1G | High affinity immunoglobulin epsilon receptor subunit gamma. (86 aa) |
| | BCL11B | B-cell lymphoma/leukemia 11B. (740 aa) |
| | FZD7 | Frizzled-7; Belongs to the G-protein coupled receptor Fz/Smo family. (574 aa) |
| | PKNOX1 | Homeobox protein PKNOX1 isoform X1. (436 aa) |
| | LOC112408488 | Serine/threonine-protein kinase B-raf-like. (250 aa) |
| | IL2RG | Cytokine receptor common subunit gamma isoform X1. (381 aa) |
| | AIRE | Autoimmune regulator. (553 aa) |
| | LOC112408947 | LOW QUALITY PROTEIN: major histocompatibility complex class I-related gene protein; Belongs to the MHC class I family. (249 aa) |
| | RC3H1 | Roquin-1 isoform X1. (1135 aa) |
| | SASH3 | SAM and SH3 domain-containing protein 3. (380 aa) |
| | THEMIS | Protein THEMIS. (647 aa) |
| | JAG2 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1064 aa) |
| | ITK | Tyrosine-protein kinase. (620 aa) |
| | JMJD6 | Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 isoform X1. (431 aa) |
| | LOC112410714 | Cathepsin L1; Belongs to the peptidase C1 family. (334 aa) |
| | ABL1 | Tyrosine-protein kinase. (1148 aa) |
| | FUT7 | Alpha-(1,3)-fucosyltransferase 7. (342 aa) |
| | RC3H2 | Roquin-2 isoform X1. (1189 aa) |
| | TSC1 | Hamartin isoform X1. (1169 aa) |
| | LEP | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa) |
| | NRARP | Notch-regulated ankyrin repeat-containing protein. (114 aa) |
| | TNFSF8 | Tumor necrosis factor ligand superfamily member 8; Belongs to the tumor necrosis factor family. (234 aa) |
| | NHEJ1 | Non-homologous end-joining factor 1 isoform X1. (299 aa) |
| | CARD11 | Caspase recruitment domain-containing protein 11 isoform X1. (1154 aa) |
| | LFNG | beta-1,3-N-acetylglucosaminyltransferase lunatic fringe. (467 aa) |
| | PTPN2 | Tyrosine-protein phosphatase non-receptor type. (396 aa) |
| | CD83 | CD83 antigen. (195 aa) |
| | PTPRC | Receptor-type tyrosine-protein phosphatase C isoform X1. (1258 aa) |
| | LEPR | Leptin receptor isoform X1. (1165 aa) |
| | PTPN22 | Tyrosine-protein phosphatase non-receptor type 22 isoform X1. (801 aa) |
| | RUNX2 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (408 aa) |
| | SRF | Serum response factor isoform X1. (535 aa) |
| | IRF4 | Interferon regulatory factor 4. (452 aa) |
| | LCK | Tyrosine-protein kinase. (509 aa) |
| | RAB44 | Ras-related protein Rab-44 isoform X1. (985 aa) |
| | CDK6 | Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa) |
