STRINGSTRING
DDX49 DDX49 IGF1 IGF1 INO80 INO80 RIMS1 RIMS1 SEMA4D SEMA4D FXN FXN NCBP1 NCBP1 HPN HPN TGFBR1 TGFBR1 POU4F2 POU4F2 ZFYVE27 ZFYVE27 DERL2 DERL2 CXCL16 CXCL16 IST1 IST1 SYT1 SYT1 BMPR2 BMPR2 MTPN MTPN MFSD2A MFSD2A SLC44A4 SLC44A4 TGFB2 TGFB2 LGI1 LGI1 CDKL5 CDKL5 LOC112396076 LOC112396076 EXOSC4 EXOSC4 RASAL1 RASAL1 COMMD5 COMMD5 MMP14 MMP14 CSNK2A1 CSNK2A1 EFNA5 EFNA5 ERBB2 ERBB2 LOC112398445 LOC112398445 SYT17 SYT17 FGFR1OP FGFR1OP EXOSC9 EXOSC9 SMURF1 SMURF1 OCM2 OCM2 HDGFL2 HDGFL2 DBNL DBNL LIMK1 LIMK1 PRKN PRKN CRABP2 CRABP2 NTN1 NTN1 PSMD10 PSMD10 F2 F2 SLC25A33 SLC25A33 MUL1 MUL1 SYT2 SYT2 CDH4 CDH4 N6AMT1 N6AMT1 TRPV2 TRPV2 PLAA PLAA ADNP2 ADNP2 NEDD4L NEDD4L BCL2 BCL2 ZNF639 ZNF639 SHTN1 SHTN1 SMAD7 SMAD7 LOC112407442 LOC112407442 GOLGA4 GOLGA4 USP47 USP47 TEAD1 TEAD1 LOC112407979 LOC112407979 SYT4 SYT4 LOC112407988 LOC112407988 DSCAM DSCAM KDM2B KDM2B DDX3X DDX3X YAP1 YAP1 SPHK1 SPHK1 RPTOR RPTOR CDKN2AIP CDKN2AIP ADAM10 ADAM10 LOC112410790 LOC112410790 WNT3 WNT3 NOL12 NOL12 ISLR2 ISLR2 ISLR ISLR SEMA7A SEMA7A TRIM32 TRIM32 EXOSC2 EXOSC2 FN1 FN1 BRAT1 BRAT1 KLHL22 KLHL22 EDN1 EDN1 TAF9B TAF9B UCN UCN NGF NGF CPNE9 CPNE9 SFRP1 SFRP1 EGFR EGFR WNT3A WNT3A SRF SRF ARMC12 ARMC12 CPNE5 CPNE5 SUPV3L1 SUPV3L1 SFN SFN CIB1 CIB1 UNC13A UNC13A EIF4G1 EIF4G1 LPAR3 LPAR3 MAP3K13 MAP3K13 MEGF8 MEGF8 LOC112415435 LOC112415435 SYT3 SYT3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DDX49Probable ATP-dependent RNA helicase DDX49; Belongs to the DEAD box helicase family. (483 aa)
IGF1Insulin-like growth factor I isoform X1. (208 aa)
INO80DNA helicase INO80 isoform X1. (1563 aa)
RIMS1LOW QUALITY PROTEIN: regulating synaptic membrane exocytosis protein 1. (1574 aa)
SEMA4Dsemaphorin-4D; Belongs to the semaphorin family. (863 aa)
FXNLOW QUALITY PROTEIN: frataxin, mitochondrial. (244 aa)
NCBP1Nuclear cap-binding protein subunit 1. (790 aa)
HPNSerine protease hepsin isoform X1; Belongs to the peptidase S1 family. (417 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (438 aa)
POU4F2POU domain protein. (408 aa)
ZFYVE27Protrudin isoform X1. (406 aa)
DERL2Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (239 aa)
CXCL16C-X-C motif chemokine 16. (316 aa)
IST1IST1 homolog isoform X1. (376 aa)
SYT1Synaptotagmin-1. (422 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1012 aa)
MTPNMyotrophin. (118 aa)
MFSD2ASodium-dependent lysophosphatidylcholine symporter 1 isoform X1. (529 aa)
SLC44A4Choline transporter-like protein 4; Belongs to the CTL (choline transporter-like) family. (706 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
LGI1Leucine-rich glioma-inactivated protein 1 isoform X1. (641 aa)
CDKL5Cyclin-dependent kinase-like 5. (940 aa)
LOC112396076ATP-dependent RNA helicase DDX3X-like; Belongs to the DEAD box helicase family. (656 aa)
EXOSC4Exosome complex component RRP41. (245 aa)
RASAL1rasGAP-activating-like protein 1 isoform X1. (838 aa)
COMMD5COMM domain-containing protein 5. (224 aa)
MMP14Matrix metalloproteinase-14. (582 aa)
CSNK2A1Casein kinase II subunit alpha; Belongs to the protein kinase superfamily. (391 aa)
EFNA5ephrin-A5 isoform X1; Belongs to the ephrin family. (228 aa)
ERBB2Receptor protein-tyrosine kinase. (1255 aa)
LOC112398445Keratin, type I cytoskeletal 17-like isoform X1; Belongs to the intermediate filament family. (449 aa)
SYT17Synaptotagmin-17 isoform X1. (505 aa)
FGFR1OPFGFR1 oncogene partner. (434 aa)
EXOSC9Exosome complex component RRP45. (439 aa)
SMURF1E3 ubiquitin-protein ligase SMURF1. (718 aa)
OCM2Putative oncomodulin-2; Belongs to the parvalbumin family. (109 aa)
HDGFL2Hepatoma-derived growth factor-related protein 2 isoform X1. (617 aa)
DBNLDrebrin-like protein isoform X1. (430 aa)
LIMK1LIM domain kinase 1. (594 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (465 aa)
CRABP2Cellular retinoic acid-binding protein 2; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (138 aa)
NTN1Netrin-1. (604 aa)
PSMD1026S proteasome non-ATPase regulatory subunit 10 isoform X1. (226 aa)
F2Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (623 aa)
SLC25A33Solute carrier family 25 member 33; Belongs to the mitochondrial carrier (TC 2.A.29) family. (321 aa)
MUL1Mitochondrial ubiquitin ligase activator of NFKB 1. (352 aa)
SYT2Synaptotagmin-2 isoform X1. (428 aa)
CDH4Cadherin-4 isoform X1; Cadherins are calcium-dependent cell adhesion proteins. (884 aa)
N6AMT1hemK methyltransferase family member 2. (214 aa)
TRPV2Transient receptor potential cation channel subfamily V member 2; Belongs to the transient receptor (TC 1.A.4) family. (761 aa)
PLAAPhospholipase A-2-activating protein. (796 aa)
ADNP2Activity-dependent neuroprotector homeobox protein 2 isoform X1. (1181 aa)
NEDD4LE3 ubiquitin-protein ligase NEDD4-like isoform X1. (1247 aa)
BCL2Apoptosis regulator Bcl-2 isoform X1. (233 aa)
ZNF639Zinc finger protein 639. (485 aa)
SHTN1Shootin-1 isoform X1. (631 aa)
SMAD7Mothers against decapentaplegic homolog. (426 aa)
LOC112407442LOW QUALITY PROTEIN: frataxin, mitochondrial-like. (215 aa)
GOLGA4Golgin subfamily A member 4 isoform X5. (2275 aa)
USP47Ubiquitin carboxyl-terminal hydrolase 47 isoform X1; Belongs to the peptidase C19 family. (1355 aa)
TEAD1Transcriptional enhancer factor TEF-1 isoform X1. (436 aa)
LOC112407979Secreted frizzled-related protein 2-like. (105 aa)
SYT4Synaptotagmin-4. (425 aa)
LOC112407988Secreted frizzled-related protein 2. (294 aa)
DSCAMDown syndrome cell adhesion molecule. (2039 aa)
KDM2BLysine-specific demethylase 2B. (1309 aa)
DDX3XATP-dependent RNA helicase DDX3X isoform X1; Belongs to the DEAD box helicase family. (662 aa)
YAP1Transcriptional coactivator YAP1. (416 aa)
SPHK1Sphingosine kinase 1. (391 aa)
RPTORRegulatory-associated protein of mTOR isoform X1. (1336 aa)
CDKN2AIPCDKN2A-interacting protein isoform X1. (582 aa)
ADAM10Disintegrin and metalloproteinase domain-containing protein 10. (748 aa)
LOC112410790Nucleolar protein 12-like. (137 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (453 aa)
NOL12Nucleolar protein 12. (214 aa)
ISLR2Immunoglobulin superfamily containing leucine-rich repeat protein 2. (747 aa)
ISLRImmunoglobulin superfamily containing leucine-rich repeat protein. (429 aa)
SEMA7Asemaphorin-7A; Belongs to the semaphorin family. (665 aa)
TRIM32E3 ubiquitin-protein ligase TRIM32. (653 aa)
EXOSC2Exosome complex component RRP4. (293 aa)
FN1Fibronectin isoform X5. (2478 aa)
BRAT1BRCA1-associated ATM activator 1 isoform X1. (869 aa)
KLHL22Kelch-like protein 22 isoform X1. (673 aa)
EDN1Endothelin-1. (202 aa)
TAF9BTranscription initiation factor TFIID subunit 9B isoform X1. (259 aa)
UCNUrocortin. (126 aa)
NGFBeta-nerve growth factor; Belongs to the NGF-beta family. (241 aa)
CPNE9Copine-9 isoform X1. (587 aa)
SFRP1Secreted frizzled-related protein 1. (296 aa)
EGFRReceptor protein-tyrosine kinase. (1156 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
SRFSerum response factor isoform X1. (535 aa)
ARMC12Armadillo repeat-containing protein 12 isoform X2. (366 aa)
CPNE5Copine-5. (593 aa)
SUPV3L1LOW QUALITY PROTEIN: ATP-dependent RNA helicase SUPV3L1, mitochondrial. (776 aa)
SFN14-3-3 protein sigma; Belongs to the 14-3-3 family. (248 aa)
CIB1Calcium and integrin-binding protein 1. (191 aa)
UNC13AProtein unc-13 homolog A. (1647 aa)
EIF4G1Eukaryotic translation initiation factor 4 gamma 1 isoform X1. (1601 aa)
LPAR3Lysophosphatidic acid receptor 3; Belongs to the G-protein coupled receptor 1 family. (355 aa)
MAP3K13Mitogen-activated protein kinase kinase kinase 13; Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. (966 aa)
MEGF8Multiple epidermal growth factor-like domains protein 8. (2784 aa)
LOC112415435LOW QUALITY PROTEIN: CDKN2A-interacting protein-like. (392 aa)
SYT3Synaptotagmin-3. (591 aa)
Your Current Organism:
Neophocaena asiaeorientalis
NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise
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