STRINGSTRING
STK11 STK11 EPHA7 EPHA7 LOC112391519 LOC112391519 SEMA3C SEMA3C CDKN1B CDKN1B SEMA4D SEMA4D INHBA INHBA RERG RERG SMARCA2 SMARCA2 CGRRF1 CGRRF1 SMAD3 SMAD3 SEMA4G SEMA4G OSGIN1 OSGIN1 ACVR1B ACVR1B CRLF3 CRLF3 ACVRL1 ACVRL1 DIP2B DIP2B SEMA3F SEMA3F LOC112394343 LOC112394343 BMPR2 BMPR2 SEMA3A SEMA3A SEMA3E SEMA3E SEMA3B SEMA3B BMP10 BMP10 SEMA3D SEMA3D GDF2 GDF2 LOC112395012 LOC112395012 TGFB2 TGFB2 CDKN2C CDKN2C ULK1 ULK1 CIRBP CIRBP RBBP7 RBBP7 TSPYL2 TSPYL2 LOC112396076 LOC112396076 OSTN OSTN NOV NOV SEMA6D SEMA6D CDHR2 CDHR2 LOC112397547 LOC112397547 SLIT2 SLIT2 PSRC1 PSRC1 MSX1 MSX1 SEMA6A SEMA6A SOX17 SOX17 KIAA1024 KIAA1024 PPP1R9B PPP1R9B DCUN1D3 DCUN1D3 SEMA4C SEMA4C FSTL4 FSTL4 PHB PHB PTPRS PTPRS RYK RYK SEMA3G SEMA3G SEMA6B SEMA6B MYL10 MYL10 LOC112400718 LOC112400718 SMARCA4 SMARCA4 PLXNA3 PLXNA3 TP53TG5 TP53TG5 CDKN2D CDKN2D IFRD2 IFRD2 WNT5A WNT5A HNF4A HNF4A GDF9 GDF9 CCAR2 CCAR2 PTPRJ PTPRJ NDUFS3 NDUFS3 CCDC85B CCDC85B SEMA4A SEMA4A ADAM15 ADAM15 TP53 TP53 NTN1 NTN1 ENO1 ENO1 MUL1 MUL1 DRAXIN DRAXIN IP6K2 IP6K2 KIAA0319 KIAA0319 NME6 NME6 CUNH10orf90 CUNH10orf90 WT1 WT1 SERTAD2 SERTAD2 SH3BP4 SH3BP4 FLCN FLCN CDKL3 CDKL3 SLIT3 SLIT3 RTN4 RTN4 SEMA5A SEMA5A FBP1 FBP1 CDK5 CDK5 BCL2 BCL2 SPART SPART OSGIN2 OSGIN2 RB1 RB1 DCSTAMP DCSTAMP SEMA5B SEMA5B LOC112407979 LOC112407979 SMAD4 SMAD4 WNT11 WNT11 ST7 ST7 LOC112407988 LOC112407988 MYL2 MYL2 ENPP1 ENPP1 TNR TNR DCBLD2 DCBLD2 DDX3X DDX3X GJA1 GJA1 FHL1 FHL1 CDKN2AIP CDKN2AIP GNG4 GNG4 WNT3 WNT3 PML PML SEMA7A SEMA7A NAIF1 NAIF1 SEMA6C SEMA6C RTN4R RTN4R SERPINE2 SERPINE2 DNAJB2 DNAJB2 ST7L ST7L SFRP1 SFRP1 WNT3A WNT3A CDKN1A CDKN1A SIRT1 SIRT1 SEMA4F SEMA4F SEMA4B SEMA4B FRZB FRZB PI16 PI16 SESN2 SESN2 BCL6 BCL6 HRG HRG YJEFN3 YJEFN3 NDUFA13 NDUFA13 SERTAD3 SERTAD3 TGFB1 TGFB1 RACK1 RACK1 SERTAD1 SERTAD1 LOC112415435 LOC112415435 GSK3A GSK3A SPHK2 SPHK2 EAF2 EAF2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
STK11Serine/threonine-protein kinase STK11 isoform X1. (546 aa)
EPHA7Ephrin type-A receptor 7. (1006 aa)
LOC112391519SERTA domain-containing protein 1-like. (238 aa)
SEMA3Csemaphorin-3C; Belongs to the semaphorin family. (751 aa)
CDKN1BCyclin-dependent kinase inhibitor 1B. (198 aa)
SEMA4Dsemaphorin-4D; Belongs to the semaphorin family. (863 aa)
INHBAInhibin beta A chain. (474 aa)
RERGRas-related and estrogen-regulated growth inhibitor isoform X1. (199 aa)
SMARCA2Probable global transcription activator SNF2L2 isoform X3. (1596 aa)
CGRRF1Cell growth regulator with RING finger domain protein 1. (332 aa)
SMAD3Mothers against decapentaplegic homolog. (376 aa)
SEMA4Gsemaphorin-4G isoform X1; Belongs to the semaphorin family. (857 aa)
OSGIN1Oxidative stress-induced growth inhibitor 1. (478 aa)
ACVR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (453 aa)
CRLF3Cytokine receptor-like factor 3 isoform X1. (430 aa)
ACVRL1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (515 aa)
DIP2BDisco-interacting protein 2 homolog B isoform X1. (1577 aa)
SEMA3Fsemaphorin-3F; Belongs to the semaphorin family. (744 aa)
LOC11239434325-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial; Belongs to the cytochrome P450 family. (508 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1012 aa)
SEMA3Asemaphorin-3A; Belongs to the semaphorin family. (772 aa)
SEMA3Esemaphorin-3E; Belongs to the semaphorin family. (715 aa)
SEMA3Bsemaphorin-3B isoform X1; Belongs to the semaphorin family. (748 aa)
BMP10Bone morphogenetic protein 10. (423 aa)
SEMA3Dsemaphorin-3D; Belongs to the semaphorin family. (777 aa)
GDF2Growth/differentiation factor 2. (431 aa)
LOC112395012Cytochrome P450 27C1; Belongs to the cytochrome P450 family. (399 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
CDKN2CCyclin-dependent kinase 4 inhibitor C. (168 aa)
ULK1Serine/threonine-protein kinase ULK1 isoform X1. (972 aa)
CIRBPCold-inducible RNA-binding protein. (172 aa)
RBBP7Histone-binding protein RBBP7 isoform X1. (425 aa)
TSPYL2Testis-specific Y-encoded-like protein 2 isoform X1; Belongs to the nucleosome assembly protein (NAP) family. (735 aa)
LOC112396076ATP-dependent RNA helicase DDX3X-like; Belongs to the DEAD box helicase family. (656 aa)
OSTNOsteocrin. (132 aa)
NOVProtein NOV homolog. (359 aa)
SEMA6Dsemaphorin-6D isoform X1; Belongs to the semaphorin family. (1073 aa)
CDHR2Cadherin-related family member 2. (1311 aa)
LOC112397547Slit homolog 2 protein-like. (162 aa)
SLIT2Slit homolog 2 protein. (1286 aa)
PSRC1Proline/serine-rich coiled-coil protein 1 isoform X1. (382 aa)
MSX1Homeobox protein MSX-1. (303 aa)
SEMA6Asemaphorin-6A isoform X1; Belongs to the semaphorin family. (1044 aa)
SOX17LOW QUALITY PROTEIN: transcription factor SOX-17. (207 aa)
KIAA1024UPF0258 protein KIAA1024 homolog. (916 aa)
PPP1R9BNeurabin-2. (815 aa)
DCUN1D3DCN1-like protein. (304 aa)
SEMA4Csemaphorin-4C; Belongs to the semaphorin family. (833 aa)
FSTL4Follistatin-related protein 4 isoform X1. (845 aa)
PHBProhibitin. (272 aa)
PTPRSLOW QUALITY PROTEIN: receptor-type tyrosine-protein phosphatase S. (2076 aa)
RYKTyrosine-protein kinase RYK. (705 aa)
SEMA3Gsemaphorin-3G isoform X1; Belongs to the semaphorin family. (773 aa)
SEMA6BLOW QUALITY PROTEIN: semaphorin-6B; Belongs to the semaphorin family. (516 aa)
MYL10Myosin regulatory light chain 10. (147 aa)
LOC112400718Hyaluronidase. (781 aa)
SMARCA4Transcription activator BRG1 isoform X2. (1649 aa)
PLXNA3plexin-A3. (1569 aa)
TP53TG5TP53-target gene 5 protein. (259 aa)
CDKN2DCyclin-dependent kinase 4 inhibitor D. (166 aa)
IFRD2Interferon-related developmental regulator 2 isoform X1. (442 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
HNF4AHepatocyte nuclear factor 4-alpha isoform X1. (484 aa)
GDF9Growth/differentiation factor 9 isoform X1. (454 aa)
CCAR2Cell cycle and apoptosis regulator protein 2. (924 aa)
PTPRJReceptor-type tyrosine-protein phosphatase eta isoform X1. (1273 aa)
NDUFS3NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial; Belongs to the complex I 30 kDa subunit family. (268 aa)
CCDC85BCoiled-coil domain-containing protein 85B. (202 aa)
SEMA4Asemaphorin-4A isoform X1; Belongs to the semaphorin family. (762 aa)
ADAM15Disintegrin and metalloproteinase domain-containing protein 15 isoform X1. (866 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (387 aa)
NTN1Netrin-1. (604 aa)
ENO1Alpha-enolase. (444 aa)
MUL1Mitochondrial ubiquitin ligase activator of NFKB 1. (352 aa)
DRAXINDraxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway. (350 aa)
IP6K2Kinase; Belongs to the inositol phosphokinase (IPK) family. (425 aa)
KIAA0319Dyslexia-associated protein KIAA0319 homolog isoform X1. (1071 aa)
NME6Nucleoside diphosphate kinase. (202 aa)
CUNH10orf90Centrosomal protein C10orf90 homolog isoform X1. (794 aa)
WT1Wilms tumor protein isoform X1. (450 aa)
SERTAD2SERTA domain-containing protein 2. (311 aa)
SH3BP4SH3 domain-binding protein 4. (959 aa)
FLCNFolliculin isoform X1. (576 aa)
CDKL3Cyclin-dependent kinase-like 3. (556 aa)
SLIT3Slit homolog 3 protein isoform X2. (1523 aa)
RTN4Reticulon. (1193 aa)
SEMA5Asemaphorin-5A isoform X1. (1073 aa)
FBP1Fructose-1,6-bisphosphatase 1; Belongs to the FBPase class 1 family. (338 aa)
CDK5Cyclin-dependent-like kinase 5; Belongs to the protein kinase superfamily. (292 aa)
BCL2Apoptosis regulator Bcl-2 isoform X1. (233 aa)
SPARTSpartin isoform X1. (667 aa)
OSGIN2Oxidative stress-induced growth inhibitor 2 isoform X1. (551 aa)
RB1Retinoblastoma-associated protein. (816 aa)
DCSTAMPDendritic cell-specific transmembrane protein isoform X1. (470 aa)
SEMA5Bsemaphorin-5B isoform X1. (1102 aa)
LOC112407979Secreted frizzled-related protein 2-like. (105 aa)
SMAD4Mothers against decapentaplegic homolog. (599 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
ST7Suppressor of tumorigenicity 7 protein isoform X1. (542 aa)
LOC112407988Secreted frizzled-related protein 2. (294 aa)
MYL2Myosin regulatory light chain 2, ventricular/cardiac muscle isoform. (166 aa)
ENPP1Ectonucleotide pyrophosphatase/phosphodiesterase family member 1. (857 aa)
TNRtenascin-R. (1358 aa)
DCBLD2Discoidin, CUB and LCCL domain-containing protein 2. (669 aa)
DDX3XATP-dependent RNA helicase DDX3X isoform X1; Belongs to the DEAD box helicase family. (662 aa)
GJA1Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (381 aa)
FHL1Four and a half LIM domains protein 1 isoform X1. (339 aa)
CDKN2AIPCDKN2A-interacting protein isoform X1. (582 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (453 aa)
PMLProtein PML isoform X1. (965 aa)
SEMA7Asemaphorin-7A; Belongs to the semaphorin family. (665 aa)
NAIF1Nuclear apoptosis-inducing factor 1. (327 aa)
SEMA6CLOW QUALITY PROTEIN: semaphorin-6C; Belongs to the semaphorin family. (884 aa)
RTN4RReticulon-4 receptor. (564 aa)
SERPINE2Glia-derived nexin; Belongs to the serpin family. (397 aa)
DNAJB2dnaJ homolog subfamily B member 2 isoform X1. (325 aa)
ST7LSuppressor of tumorigenicity 7 protein-like isoform X1. (556 aa)
SFRP1Secreted frizzled-related protein 1. (296 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
CDKN1ACyclin-dependent kinase inhibitor 1. (164 aa)
SIRT1NAD-dependent protein deacetylase sirtuin-1 isoform X1. (557 aa)
SEMA4Fsemaphorin-4F isoform X3; Belongs to the semaphorin family. (772 aa)
SEMA4Bsemaphorin-4B; Belongs to the semaphorin family. (822 aa)
FRZBSecreted frizzled-related protein 3. (325 aa)
PI16Peptidase inhibitor 16; Belongs to the CRISP family. (463 aa)
SESN2Sestrin-2. (471 aa)
BCL6B-cell lymphoma 6 protein. (706 aa)
HRGLOW QUALITY PROTEIN: histidine-rich glycoprotein. (427 aa)
YJEFN3yjeF N-terminal domain-containing protein 3. (249 aa)
NDUFA13LOW QUALITY PROTEIN: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13. (164 aa)
SERTAD3SERTA domain-containing protein 3. (198 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa)
RACK1Receptor of activated protein C kinase 1. (317 aa)
SERTAD1SERTA domain-containing protein 1. (239 aa)
LOC112415435LOW QUALITY PROTEIN: CDKN2A-interacting protein-like. (392 aa)
GSK3AGlycogen synthase kinase-3 alpha. (320 aa)
SPHK2Sphingosine kinase 2 isoform X1. (655 aa)
EAF2ELL-associated factor 2. (264 aa)
Your Current Organism:
Neophocaena asiaeorientalis
NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise
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