STRINGSTRING
MECP2 MECP2 APOH APOH SLC9A3R1 SLC9A3R1 CARD10 CARD10 GPR18 GPR18 CX3CR1 CX3CR1 RAP2B RAP2B PFN2 PFN2 RRAS RRAS FUZ FUZ LOC112415400 LOC112415400 ADIPOQ ADIPOQ CHRD CHRD TGFB1 TGFB1 ANGPT2 ANGPT2 PATZ1 PATZ1 WDR63 WDR63 CALR CALR PODNL1 PODNL1 HRG HRG IL27RA IL27RA NEXMIF NEXMIF KRIT1 KRIT1 MEOX2 MEOX2 PTPRU PTPRU CLIC4 CLIC4 NODAL NODAL LOC112414158 LOC112414158 ABHD2 ABHD2 DLC1 DLC1 SFRP1 SFRP1 ADORA3 ADORA3 ADTRP ADTRP LOC112410324 LOC112410324 HDAC5 HDAC5 GJA1 GJA1 PTPRK PTPRK EMILIN2 EMILIN2 LOC112409173 LOC112409173 ADARB1 ADARB1 LOC112407988 LOC112407988 LOC112408496 LOC112408496 EPHA1 EPHA1 LOC112408488 LOC112408488 EVL EVL TCAF1 TCAF1 BMPR1A BMPR1A NR2F2 NR2F2 DPYSL3 DPYSL3 CSNK2B CSNK2B NKX2-1 NKX2-1 FAM102A FAM102A DAB2IP DAB2IP SCAI SCAI ENG ENG C5 C5 NOTCH1 NOTCH1 IGFBP5 IGFBP5 RECK RECK PIP5KL1 PIP5KL1 NEDD9 NEDD9 LDLRAD4 LDLRAD4 EPHA4 EPHA4 CLDN5 CLDN5 ADIPOR1 ADIPOR1 EMILIN1 EMILIN1 BCR BCR SPRED1 SPRED1 NOG NOG WNT11 WNT11 LOC112408148 LOC112408148 LOC112407979 LOC112407979 MMP28 MMP28 TP53INP1 TP53INP1 ARHGAP4 ARHGAP4 TACSTD2 TACSTD2 PLXNB3 PLXNB3 STARD13 STARD13 HOXA7 HOXA7 MMRN2 MMRN2 CD74 CD74 THBS1 THBS1 DLL4 DLL4 COL3A1 COL3A1 ARHGDIB ARHGDIB KANK1 KANK1 MEF2C MEF2C TMEFF2 TMEFF2 CDH1 CDH1 RNF20 RNF20 GCSAM GCSAM JAG1 JAG1 MARVELD3 MARVELD3 DPP4 DPP4 GADD45A GADD45A PHLDB2 PHLDB2 OSBPL8 OSBPL8 NF1 NF1 FOXO3 FOXO3 LRCH1 LRCH1 ARID2 ARID2 ACVR1C ACVR1C NAV3 NAV3 LOC112394151 LOC112394151 ACVRL1 ACVRL1 BCL2 BCL2 DNAJA4 DNAJA4 PTGER4 PTGER4 DACH1 DACH1 CXCL13 CXCL13 DRD2 DRD2 DUSP1 DUSP1 CCL21 CCL21 LOC112405151 LOC112405151 MYOCD MYOCD FLCN FLCN TNFAIP6 TNFAIP6 APOD APOD THY1 THY1 PTPN23 PTPN23 RIPOR2 RIPOR2 RNF41 RNF41 SRGAP1 SRGAP1 LOC112394359 LOC112394359 LOC112393870 LOC112393870 ITGB1BP1 ITGB1BP1 RIN3 RIN3 ATP2B4 ATP2B4 NDRG4 NDRG4 DUSP10 DUSP10 SRGAP2 SRGAP2 STK26 STK26 PADI2 PADI2 MIIP MIIP TIMP1 TIMP1 CORO1B CORO1B IGFBP3 IGFBP3 ADAM15 ADAM15 PTPRJ PTPRJ RHOA RHOA PTPRR PTPRR BMP10 BMP10 VASH1 VASH1 GDF2 GDF2 AIF1 AIF1 LY6G5B LY6G5B SHH SHH PODN PODN SYNJ2BP SYNJ2BP STAP1 STAP1 ADA ADA PTPRT PTPRT ZMYND8 ZMYND8 SINHCAF SINHCAF ADGRG1 ADGRG1 ABHD6 ABHD6 MITF MITF LOC112400718 LOC112400718 PTPRG PTPRG WASL WASL JUP JUP NISCH NISCH PRKG1 PRKG1 SVBP SVBP CLDN19 CLDN19 FGF2 FGF2 CUNH16orf45 CUNH16orf45 STAT3 STAT3 TIE1 TIE1 LOC112399208 LOC112399208 NGFR NGFR LOC112398455 LOC112398455 MCC MCC ANGPT4 ANGPT4 BRAF BRAF PDCD10 PDCD10 TBX5 TBX5 RAP2C RAP2C SLIT2 SLIT2 LOC112397547 LOC112397547 FAM102B FAM102B CORO1C CORO1C SEMA6D SEMA6D TRIB1 TRIB1 NOV NOV LOC112397082 LOC112397082 ROBO1 ROBO1 CNN2 CNN2 TBXA2R TBXA2R NRG3 NRG3 SRGAP3 SRGAP3 CITED2 CITED2 STK24 STK24 LOC112395837 LOC112395837 CCL28 CCL28 CXCL12 CXCL12 DLG5 DLG5 RAP2A RAP2A SULF1 SULF1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MECP2Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (470 aa)
APOHBeta-2-glycoprotein 1 isoform X1. (345 aa)
SLC9A3R1Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (366 aa)
CARD10Caspase recruitment domain-containing protein 10. (997 aa)
GPR18N-arachidonyl glycine receptor; Belongs to the G-protein coupled receptor 1 family. (354 aa)
CX3CR1CX3C chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (358 aa)
RAP2BRas-related protein Rap-2b. (183 aa)
PFN2Profilin; Belongs to the profilin family. (122 aa)
RRASRas-related protein R-Ras. (209 aa)
FUZProtein fuzzy homolog isoform X1. (440 aa)
LOC112415400C5a anaphylatoxin chemotactic receptor 2-like isoform X1. (383 aa)
ADIPOQAdiponectin. (243 aa)
CHRDChordin. (851 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa)
ANGPT2Angiopoietin-2 isoform X1. (496 aa)
PATZ1POZ-, AT hook-, and zinc finger-containing protein 1 isoform X1. (687 aa)
WDR63WD repeat-containing protein 63. (924 aa)
CALRCalreticulin. (417 aa)
PODNL1Podocan-like protein 1. (575 aa)
HRGLOW QUALITY PROTEIN: histidine-rich glycoprotein. (427 aa)
IL27RAInterleukin-27 receptor subunit alpha isoform X1. (656 aa)
NEXMIFNeurite extension and migration factor. (1515 aa)
KRIT1Krev interaction trapped protein 1 isoform X1. (747 aa)
MEOX2Homeobox protein MOX-2. (303 aa)
PTPRUReceptor-type tyrosine-protein phosphatase U isoform X1. (1463 aa)
CLIC4Chloride intracellular channel protein 4 isoform X1. (253 aa)
NODALNodal homolog. (348 aa)
LOC112414158Arpin. (292 aa)
ABHD2Monoacylglycerol lipase ABHD2. (425 aa)
DLC1Rho GTPase-activating protein 7 isoform X1. (1528 aa)
SFRP1Secreted frizzled-related protein 1. (296 aa)
ADORA3Adenosine receptor A3 isoform X1; Belongs to the G-protein coupled receptor 1 family. (356 aa)
ADTRPAndrogen-dependent TFPI-regulating protein isoform X1. (279 aa)
LOC112410324CMRF35-like molecule 8 isoform X1. (378 aa)
HDAC5Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1112 aa)
GJA1Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (381 aa)
PTPRKReceptor-type tyrosine-protein phosphatase kappa isoform X1. (1439 aa)
EMILIN2EMILIN-2. (992 aa)
LOC112409173Ras-related protein Rap-2a-like. (200 aa)
ADARB1Double-stranded RNA-specific editase 1. (701 aa)
LOC112407988Secreted frizzled-related protein 2. (294 aa)
LOC112408496TRPM8 channel-associated factor 2-like. (919 aa)
EPHA1Ephrin type-A receptor 1 isoform X1. (981 aa)
LOC112408488Serine/threonine-protein kinase B-raf-like. (250 aa)
EVLena/VASP-like protein; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family. (371 aa)
TCAF1TRPM8 channel-associated factor 1. (921 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
NR2F2COUP transcription factor 2 isoform X1. (281 aa)
DPYSL3Dihydropyrimidinase-related protein 3 isoform X1. (684 aa)
CSNK2BCasein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (215 aa)
NKX2-1Homeobox protein Nkx-2.1 isoform X1. (396 aa)
FAM102AProtein FAM102A. (384 aa)
DAB2IPDisabled homolog 2-interacting protein isoform X1. (1071 aa)
SCAIProtein SCAI; Tumor suppressor which functions to suppress MRTFA-induced SRF transcriptional activity. (606 aa)
ENGEndoglin. (652 aa)
C5Complement C5. (1677 aa)
NOTCH1LOW QUALITY PROTEIN: neurogenic locus notch homolog protein 1. (2633 aa)
IGFBP5Insulin-like growth factor-binding protein 5 isoform X1. (278 aa)
RECKReversion-inducing cysteine-rich protein with Kazal motifs isoform X1. (971 aa)
PIP5KL1Phosphatidylinositol 4-phosphate 5-kinase-like protein 1 isoform X1. (413 aa)
NEDD9Enhancer of filamentation 1 isoform X2. (829 aa)
LDLRAD4LOW QUALITY PROTEIN: low-density lipoprotein receptor class A domain-containing protein 4. (322 aa)
EPHA4Ephrin type-A receptor 4 isoform X1. (986 aa)
CLDN5Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (218 aa)
ADIPOR1Adiponectin receptor protein 1. (375 aa)
EMILIN1EMILIN-1. (1015 aa)
BCRBreakpoint cluster region protein. (1367 aa)
SPRED1Sprouty-related, EVH1 domain-containing protein 1 isoform X1. (445 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
LOC112408148LOW QUALITY PROTEIN: tumor-associated calcium signal transducer 2-like. (329 aa)
LOC112407979Secreted frizzled-related protein 2-like. (105 aa)
MMP28Matrix metalloproteinase-28 isoform X1. (520 aa)
TP53INP1Tumor protein p53-inducible nuclear protein 1 isoform X1. (240 aa)
ARHGAP4Rho GTPase-activating protein 4. (899 aa)
TACSTD2Tumor-associated calcium signal transducer 2. (419 aa)
PLXNB3plexin-B3. (1986 aa)
STARD13stAR-related lipid transfer protein 13 isoform X1. (1126 aa)
HOXA7Homeobox protein Hox-A7. (233 aa)
MMRN2Multimerin-2. (935 aa)
CD74HLA class II histocompatibility antigen gamma chain isoform X1. (278 aa)
THBS1Thrombospondin-1. (1170 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa)
COL3A1Collagen alpha-1(III) chain. (1463 aa)
ARHGDIBRho GDP-dissociation inhibitor 2. (199 aa)
KANK1KN motif and ankyrin repeat domain-containing protein 1 isoform X1. (1351 aa)
MEF2CMyocyte-specific enhancer factor 2C isoform X4. (483 aa)
TMEFF2Tomoregulin-2. (374 aa)
CDH1Cadherin-1; Cadherins are calcium-dependent cell adhesion proteins. (885 aa)
RNF20E3 ubiquitin protein ligase; Belongs to the BRE1 family. (975 aa)
GCSAMGerminal center-associated signaling and motility protein. (164 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1177 aa)
MARVELD3MARVEL domain-containing protein 3 isoform X2. (384 aa)
DPP4Dipeptidyl peptidase 4 isoform X1; Belongs to the peptidase S9B family. (766 aa)
GADD45AGrowth arrest and DNA damage-inducible protein GADD45 alpha. (165 aa)
PHLDB2Pleckstrin homology-like domain family B member 2 isoform X1. (1261 aa)
OSBPL8Oxysterol-binding protein; Belongs to the OSBP family. (889 aa)
NF1Neurofibromin isoform X1. (2841 aa)
FOXO3Forkhead box protein O3. (672 aa)
LRCH1Leucine-rich repeat and calponin homology domain-containing protein 1 isoform X3. (727 aa)
ARID2AT-rich interactive domain-containing protein 2. (1836 aa)
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (493 aa)
NAV3Neuron navigator 3 isoform X1. (2385 aa)
LOC112394151C-C motif chemokine. (99 aa)
ACVRL1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (515 aa)
BCL2Apoptosis regulator Bcl-2 isoform X1. (233 aa)
DNAJA4dnaJ homolog subfamily A member 4 isoform X1. (375 aa)
PTGER4Prostaglandin E2 receptor EP4 subtype; Belongs to the G-protein coupled receptor 1 family. (486 aa)
DACH1Dachshund homolog 1. (517 aa)
CXCL13C-X-C motif chemokine 13. (109 aa)
DRD2D(2) dopamine receptor isoform X2; Belongs to the G-protein coupled receptor 1 family. (443 aa)
DUSP1Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (367 aa)
CCL21C-C motif chemokine 21 isoform X1. (131 aa)
LOC112405151Cytochrome P450 1B1; Belongs to the cytochrome P450 family. (543 aa)
MYOCDMyocardin isoform X1. (937 aa)
FLCNFolliculin isoform X1. (576 aa)
TNFAIP6Tumor necrosis factor-inducible gene 6 protein isoform X1. (284 aa)
APODApolipoprotein D isoform X1; Belongs to the calycin superfamily. Lipocalin family. (243 aa)
THY1Thy-1 membrane glycoprotein. (161 aa)
PTPN23LOW QUALITY PROTEIN: tyrosine-protein phosphatase non-receptor type 23. (1624 aa)
RIPOR2Rho family-interacting cell polarization regulator 2 isoform X6. (1097 aa)
RNF41E3 ubiquitin-protein ligase NRDP1 isoform X1. (317 aa)
SRGAP1SLIT-ROBO Rho GTPase-activating protein 1. (1085 aa)
LOC112394359Receptor-type tyrosine-protein phosphatase R-like. (121 aa)
LOC112393870Ras and Rab interactor 3-like. (235 aa)
ITGB1BP1Integrin beta-1-binding protein 1 isoform X1. (206 aa)
RIN3Ras and Rab interactor 3. (658 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1243 aa)
NDRG4Protein NDRG4 isoform X1. (402 aa)
DUSP10Dual specificity protein phosphatase 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (482 aa)
SRGAP2SLIT-ROBO Rho GTPase-activating protein 2 isoform X1. (1084 aa)
STK26Serine/threonine-protein kinase 26. (464 aa)
PADI2Protein-arginine deiminase type-2 isoform X1. (665 aa)
MIIPMigration and invasion-inhibitory protein isoform X1. (385 aa)
TIMP1Metalloproteinase inhibitor 1. (260 aa)
CORO1BCoronin; Belongs to the WD repeat coronin family. (641 aa)
IGFBP3Insulin-like growth factor-binding protein 3. (120 aa)
ADAM15Disintegrin and metalloproteinase domain-containing protein 15 isoform X1. (866 aa)
PTPRJReceptor-type tyrosine-protein phosphatase eta isoform X1. (1273 aa)
RHOATransforming protein RhoA. (193 aa)
PTPRRReceptor-type tyrosine-protein phosphatase R isoform X1. (410 aa)
BMP10Bone morphogenetic protein 10. (423 aa)
VASH1Vasohibin-1. (363 aa)
GDF2Growth/differentiation factor 2. (431 aa)
AIF1Allograft inflammatory factor 1. (147 aa)
LY6G5BLymphocyte antigen 6 complex locus protein G5b. (197 aa)
SHHSonic hedgehog protein. (328 aa)
PODNPodocan. (607 aa)
SYNJ2BPSynaptojanin-2-binding protein. (145 aa)
STAP1LOW QUALITY PROTEIN: signal-transducing adaptor protein 1. (166 aa)
ADAAdenosine deaminase isoform X1. (402 aa)
PTPRTReceptor-type tyrosine-protein phosphatase T. (1449 aa)
ZMYND8Protein kinase C-binding protein 1. (1154 aa)
SINHCAFLOW QUALITY PROTEIN: SIN3-HDAC complex-associated factor. (221 aa)
ADGRG1Adhesion G-protein coupled receptor G1; Belongs to the G-protein coupled receptor 2 family. (685 aa)
ABHD6Monoacylglycerol lipase ABHD6. (337 aa)
MITFMicrophthalmia-associated transcription factor isoform X1. (526 aa)
LOC112400718Hyaluronidase. (781 aa)
PTPRGReceptor-type tyrosine-protein phosphatase gamma isoform X1. (1440 aa)
WASLNeural Wiskott-Aldrich syndrome protein. (545 aa)
JUPJunction plakoglobin. (744 aa)
NISCHNischarin. (1601 aa)
PRKG1cGMP-dependent protein kinase. (686 aa)
SVBPSmall vasohibin-binding protein. (66 aa)
CLDN19Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (224 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (304 aa)
CUNH16orf45Uncharacterized protein C16orf45 homolog. (204 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
TIE1Tyrosine-protein kinase receptor Tie-1. (1139 aa)
LOC112399208Rab5 GDP/GTP exchange factor isoform X4. (680 aa)
NGFRTumor necrosis factor receptor superfamily member 16. (427 aa)
LOC112398455LOW QUALITY PROTEIN: keratin, type I cytoskeletal 16-like; Belongs to the intermediate filament family. (408 aa)
MCCColorectal mutant cancer protein isoform X1. (829 aa)
ANGPT4Angiopoietin-4. (498 aa)
BRAFSerine/threonine-protein kinase B-raf isoform X1. (581 aa)
PDCD10Programmed cell death protein 10. (212 aa)
TBX5T-box transcription factor TBX5. (519 aa)
RAP2CRas-related protein Rap-2c isoform X1. (183 aa)
SLIT2Slit homolog 2 protein. (1286 aa)
LOC112397547Slit homolog 2 protein-like. (162 aa)
FAM102BProtein FAM102B isoform X1. (361 aa)
CORO1CCoronin; Belongs to the WD repeat coronin family. (474 aa)
SEMA6Dsemaphorin-6D isoform X1; Belongs to the semaphorin family. (1073 aa)
TRIB1Tribbles homolog 1. (372 aa)
NOVProtein NOV homolog. (359 aa)
LOC112397082LOW QUALITY PROTEIN: epiplakin-like. (245 aa)
ROBO1Roundabout homolog 1. (1613 aa)
CNN2Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (309 aa)
TBXA2RThromboxane A2 receptor isoform X1; Belongs to the G-protein coupled receptor 1 family. (343 aa)
NRG3Pro-neuregulin-3, membrane-bound isoform isoform X3. (613 aa)
SRGAP3SLIT-ROBO Rho GTPase-activating protein 3 isoform X1. (1099 aa)
CITED2Cbp/p300-interacting transactivator 2. (263 aa)
STK24Serine/threonine-protein kinase 24 isoform X1. (531 aa)
LOC112395837LOW QUALITY PROTEIN: calreticulin-like. (540 aa)
CCL28C-C motif chemokine. (127 aa)
CXCL12Stromal cell-derived factor 1 isoform X3; Belongs to the intercrine alpha (chemokine CxC) family. (119 aa)
DLG5Disks large homolog 5; Belongs to the MAGUK family. (1921 aa)
RAP2ARas-related protein Rap-2a isoform X1. (183 aa)
SULF1Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family. (882 aa)
Your Current Organism:
Neophocaena asiaeorientalis
NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise
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