STRINGSTRING
NCOA2 NCOA2 MED17 MED17 SLC30A9 SLC30A9 ACTN4 ACTN4 SFR1 SFR1 PPRC1 PPRC1 CALCOCO1 CALCOCO1 LOC112394913 LOC112394913 PPARGC1B PPARGC1B ACTN1 ACTN1 ZMIZ1 ZMIZ1 ENY2 ENY2 ETS1 ETS1 DCAF6 DCAF6 MED1 MED1 NCOA6 NCOA6 PRKCB PRKCB FGF2 FGF2 ZMIZ2 ZMIZ2 BUD31 BUD31 PPARGC1A PPARGC1A PSMC3IP PSMC3IP NCOA3 NCOA3 TMF1 TMF1 CCAR2 CCAR2 ELK1 ELK1 RBM14 RBM14 HELZ2 HELZ2 SRA1 SRA1 LOC112404478 LOC112404478 USP22 USP22 LOC112404477 LOC112404477 LOC112404351 LOC112404351 SS18 SS18 CCDC62 CCDC62 NCOA7 NCOA7 ATXN7L3 ATXN7L3 ACTN2 ACTN2 CNOT9 CNOT9 NCOA1 NCOA1 TADA3 TADA3 CNOT6 CNOT6 WDR77 WDR77 TACC1 TACC1 CCAR1 CCAR1 KDM1A KDM1A PKN1 PKN1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NCOA2Nuclear receptor coactivator. (1464 aa)
MED17Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (651 aa)
SLC30A9Zinc transporter 9. (565 aa)
ACTN4Alpha-actinin-4 isoform X2. (827 aa)
SFR1Swi5-dependent recombination DNA repair protein 1 homolog isoform X1. (232 aa)
PPRC1Peroxisome proliferator-activated receptor gamma coactivator-related protein 1 isoform X1. (1674 aa)
CALCOCO1Calcium-binding and coiled-coil domain-containing protein 1 isoform X1. (692 aa)
LOC112394913Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for trans [...] (112 aa)
PPARGC1BPeroxisome proliferator-activated receptor gamma coactivator 1-beta isoform X1. (1019 aa)
ACTN1Alpha-actinin-1 isoform X1. (926 aa)
ZMIZ1Zinc finger MIZ domain-containing protein 1. (1065 aa)
ENY2Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for trans [...] (101 aa)
ETS1Protein C-ets-1 isoform X1. (441 aa)
DCAF6DDB1- and CUL4-associated factor 6 isoform X1. (938 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1579 aa)
NCOA6Nuclear receptor coactivator 6 isoform X1. (2039 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (304 aa)
ZMIZ2Zinc finger MIZ domain-containing protein 2 isoform X1. (933 aa)
BUD31Protein BUD31 homolog isoform X1. (149 aa)
PPARGC1APeroxisome proliferator-activated receptor gamma coactivator 1-alpha isoform X1. (799 aa)
PSMC3IPHomologous-pairing protein 2 homolog isoform X1. (217 aa)
NCOA3Nuclear receptor coactivator. (1400 aa)
TMF1TATA element modulatory factor isoform X1. (1093 aa)
CCAR2Cell cycle and apoptosis regulator protein 2. (924 aa)
ELK1ETS domain-containing protein Elk-1 isoform X1. (442 aa)
RBM14RNA-binding protein 14 isoform X1. (669 aa)
HELZ2LOW QUALITY PROTEIN: helicase with zinc finger domain 2. (1880 aa)
SRA1Steroid receptor RNA activator 1 isoform X1. (278 aa)
LOC112404478Bromodomain-containing protein 8-like. (236 aa)
USP22Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (531 aa)
LOC112404477Bromodomain-containing protein 8-like. (101 aa)
LOC112404351Bromodomain-containing protein 8 isoform X1. (951 aa)
SS18Protein SSXT isoform X1. (418 aa)
CCDC62Coiled-coil domain-containing protein 62. (679 aa)
NCOA7Nuclear receptor coactivator 7 isoform X1. (943 aa)
ATXN7L3Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...] (354 aa)
ACTN2Alpha-actinin-2 isoform X1. (894 aa)
CNOT9CCR4-NOT transcription complex subunit 9. (299 aa)
NCOA1Nuclear receptor coactivator. (1441 aa)
TADA3Transcriptional adapter 3. (432 aa)
CNOT6CCR4-NOT transcription complex subunit 6 isoform X1. (557 aa)
WDR77Methylosome protein 50 isoform X1. (342 aa)
TACC1Transforming acidic coiled-coil-containing protein 1 isoform X1. (798 aa)
CCAR1Cell division cycle and apoptosis regulator protein 1. (1150 aa)
KDM1ALysine-specific histone demethylase 1A. (730 aa)
PKN1Serine/threonine-protein kinase N1 isoform X1. (950 aa)
Your Current Organism:
Neophocaena asiaeorientalis
NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.