STRINGSTRING
DDX5 DDX5 BMPR1A BMPR1A SMPD3 SMPD3 GDF3 GDF3 HJV HJV LOC112391706 LOC112391706 ETV2 ETV2 ATF2 ATF2 SMAD3 SMAD3 BMP4 BMP4 BMPR1B BMPR1B SMAD6 SMAD6 ACVR1 ACVR1 ACVRL1 ACVRL1 USP15 USP15 SMAD1 SMAD1 SLC39A5 SLC39A5 BMPR2 BMPR2 BMP10 BMP10 BMP8A BMP8A TGFB3 TGFB3 GDF2 GDF2 TGFB2 TGFB2 BMP6 BMP6 FST FST LOC112396051 LOC112396051 SLC33A1 SLC33A1 EXT1 EXT1 LEF1 LEF1 MSX1 MSX1 GDF5 GDF5 ACVR2A ACVR2A TGFBR3 TGFBR3 MAPK3 MAPK3 SMURF1 SMURF1 TGFBR3L TGFBR3L DLX3 DLX3 WNT5A WNT5A GDF7 GDF7 CHRDL1 CHRDL1 ZNF831 ZNF831 ZCCHC12 ZCCHC12 BMPER BMPER BMP7 BMP7 HFE HFE SMAD5 SMAD5 EGR1 EGR1 HES1 HES1 LOC112404952 LOC112404952 FAM83G FAM83G LOC112404954 LOC112404954 BMP5 BMP5 LOC112406365 LOC112406365 SPART SPART SMAD9 SMAD9 PDCD4 PDCD4 GDF6 GDF6 SMAD7 SMAD7 SMAD2 SMAD2 LOC112407979 LOC112407979 SMAD4 SMAD4 NOG NOG LOC112407988 LOC112407988 TMEM100 TMEM100 LOC112409615 LOC112409615 LOC112409616 LOC112409616 HES5 HES5 SOST SOST TMPRSS6 TMPRSS6 ABL1 ABL1 HIVEP1 HIVEP1 TWSG1 TWSG1 NOTCH2 NOTCH2 SFRP1 SFRP1 BMP2 BMP2 LOC112413503 LOC112413503 CCDC142 CCDC142 RUNX2 RUNX2 NODAL NODAL RGMB RGMB SOSTDC1 SOSTDC1 DLX5 DLX5 GDF1 GDF1 COMP COMP RGMA RGMA CHRD CHRD MEGF8 MEGF8 GDF15 GDF15
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DDX5Probable ATP-dependent RNA helicase DDX5; Belongs to the DEAD box helicase family. (614 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
SMPD3Sphingomyelin phosphodiesterase 3. (653 aa)
GDF3Growth/differentiation factor 3. (364 aa)
HJVHemojuvelin. (427 aa)
LOC112391706Homeobox protein NANOG-like. (225 aa)
ETV2LOW QUALITY PROTEIN: ETS translocation variant 2. (374 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2 isoform X1. (505 aa)
SMAD3Mothers against decapentaplegic homolog. (376 aa)
BMP4Bone morphogenetic protein 4 isoform X1. (420 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
SMAD6LOW QUALITY PROTEIN: mothers against decapentaplegic homolog 6. (422 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
ACVRL1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (515 aa)
USP15Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (981 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
SLC39A5Zinc transporter ZIP5. (541 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1012 aa)
BMP10Bone morphogenetic protein 10. (423 aa)
BMP8ABone morphogenetic protein 8A. (402 aa)
TGFB3Transforming growth factor beta-3. (456 aa)
GDF2Growth/differentiation factor 2. (431 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
BMP6Bone morphogenetic protein 6. (309 aa)
FSTFollistatin. (344 aa)
LOC112396051Probable ubiquitin carboxyl-terminal hydrolase FAF-X isoform X1; Belongs to the peptidase C19 family. (2556 aa)
SLC33A1Acetyl-coenzyme A transporter 1. (550 aa)
EXT1Exostosin-1; Belongs to the glycosyltransferase 47 family. (746 aa)
LEF1Lymphoid enhancer-binding factor 1 isoform X1. (414 aa)
MSX1Homeobox protein MSX-1. (303 aa)
GDF5Growth/differentiation factor 5. (499 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (513 aa)
TGFBR3Transforming growth factor beta receptor type 3 isoform X1. (851 aa)
MAPK3Mitogen-activated protein kinase 3. (265 aa)
SMURF1E3 ubiquitin-protein ligase SMURF1. (718 aa)
TGFBR3LLOW QUALITY PROTEIN: transforming growth factor-beta receptor type 3-like protein. (412 aa)
DLX3Homeobox protein DLX-3. (287 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
GDF7Growth/differentiation factor 7. (381 aa)
CHRDL1Chordin-like protein 1. (458 aa)
ZNF831Zinc finger protein 831 isoform X1. (1632 aa)
ZCCHC12Zinc finger CCHC domain-containing protein 12. (403 aa)
BMPERBMP-binding endothelial regulator protein. (685 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
HFEHereditary hemochromatosis protein isoform X1; Belongs to the MHC class I family. (356 aa)
SMAD5Mothers against decapentaplegic homolog. (465 aa)
EGR1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (531 aa)
HES1Transcription factor HES-1. (280 aa)
LOC112404952Left-right determination factor 2-like. (217 aa)
FAM83GProtein FAM83G. (817 aa)
LOC112404954Left-right determination factor 2-like. (252 aa)
BMP5Bone morphogenetic protein 5 isoform X2. (455 aa)
LOC112406365LOW QUALITY PROTEIN: homeobox protein NANOG-like. (294 aa)
SPARTSpartin isoform X1. (667 aa)
SMAD9Mothers against decapentaplegic homolog. (440 aa)
PDCD4Programmed cell death protein 4 isoform X1. (485 aa)
GDF6Growth/differentiation factor 6. (462 aa)
SMAD7Mothers against decapentaplegic homolog. (426 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
LOC112407979Secreted frizzled-related protein 2-like. (105 aa)
SMAD4Mothers against decapentaplegic homolog. (599 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
LOC112407988Secreted frizzled-related protein 2. (294 aa)
TMEM100Transmembrane protein 100. (134 aa)
LOC112409615Probable ubiquitin carboxyl-terminal hydrolase FAF-X. (235 aa)
LOC112409616Probable ubiquitin carboxyl-terminal hydrolase FAF-X; Belongs to the peptidase C19 family. (2060 aa)
HES5Transcription factor HES-5. (94 aa)
SOSTSclerostin. (212 aa)
TMPRSS6Transmembrane protease serine 6; Belongs to the peptidase S1 family. (800 aa)
ABL1Tyrosine-protein kinase. (1148 aa)
HIVEP1Zinc finger protein 40 isoform X1. (2751 aa)
TWSG1Twisted gastrulation protein homolog 1. (223 aa)
NOTCH2Neurogenic locus notch homolog protein 2 isoform X1. (2485 aa)
SFRP1Secreted frizzled-related protein 1. (296 aa)
BMP2Bone morphogenetic protein 2 isoform X1. (395 aa)
LOC112413503Zinc finger CCHC domain-containing protein 18-like. (402 aa)
CCDC142Coiled-coil domain-containing protein 142. (764 aa)
RUNX2Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (408 aa)
NODALNodal homolog. (348 aa)
RGMBRGM domain family member B. (441 aa)
SOSTDC1Sclerostin domain-containing protein 1. (206 aa)
DLX5Homeobox protein DLX-5. (289 aa)
GDF1Embryonic growth/differentiation factor 1. (203 aa)
COMPCartilage oligomeric matrix protein. (756 aa)
RGMARepulsive guidance molecule A. (454 aa)
CHRDChordin. (851 aa)
MEGF8Multiple epidermal growth factor-like domains protein 8. (2784 aa)
GDF15Growth/differentiation factor 15. (308 aa)
Your Current Organism:
Neophocaena asiaeorientalis
NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise
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