STRINGSTRING
EZH2 EZH2 LMX1A LMX1A SCRIB SCRIB LHX5 LHX5 LEF1 LEF1 PTPN11 PTPN11 CNTN1 CNTN1 EN2 EN2 KLHL4 KLHL4 SHH SHH TTLL1 TTLL1 SEZ6 SEZ6 OPHN1 OPHN1 CDK5R1 CDK5R1 GLI1 GLI1 SMAD1 SMAD1 TBR1 TBR1 WNT1 WNT1 FAIM2 FAIM2 GRID2 GRID2 RORA RORA LDB1 LDB1 AARS AARS TTC21B TTC21B CRK CRK SKOR2 SKOR2 MAP2K1 MAP2K1 EN1 EN1 ATF2 ATF2 ASCL1 ASCL1 KLHL5 KLHL5 PHOX2A PHOX2A PHOX2B PHOX2B XRCC1 XRCC1 COQ8B COQ8B ALDH1A2 ALDH1A2 NEUROD1 NEUROD1 ITGB1 ITGB1 ZNF365 ZNF365 LRRC1 LRRC1 PTF1A PTF1A GNPAT GNPAT EGR2 EGR2 NHLH2 NHLH2 CRKL CRKL SERPINE2 SERPINE2 CDK5R2 CDK5R2 FZD4 FZD4 FAM205A FAM205A HSPA5 HSPA5 SMO SMO ABL1 ABL1 WHRN WHRN NFIB NFIB B4GALT2 B4GALT2 POU4F1 POU4F1 ARL13B ARL13B CBS CBS AHI1 AHI1 KDM2B KDM2B KCNE1 KCNE1 LHX1 LHX1 NOG NOG PDSS2 PDSS2 NANOS1 NANOS1 HOXA2 HOXA2 MECP2 MECP2 BCL2 BCL2 CDK5 CDK5 CTNNB1 CTNNB1 AGTPBP1 AGTPBP1 OTX1 OTX1 GBX2 GBX2 HES1 HES1 PROX1 PROX1 PLXNA2 PLXNA2 ARCN1 ARCN1 BMP7 BMP7 NHLH1 NHLH1 KIF14 KIF14 RERE RERE CLP1 CLP1 SPTBN2 SPTBN2 CEND1 CEND1 KLHL1 KLHL1 GBA GBA RPGRIP1L RPGRIP1L CBLN1 CBLN1 GSX2 GSX2 ZNF423 ZNF423 NAGLU NAGLU NEUROD2 NEUROD2 LOC112400373 LOC112400373 PTPRS PTPRS HOXB1 HOXB1 OGDH OGDH DLL1 DLL1 KAT2A KAT2A FGF2 FGF2 SEZ6L2 SEZ6L2 HAP1 HAP1 SEMA4C SEMA4C ATRN ATRN RBFOX2 RBFOX2 HOXB2 HOXB2 MAFB MAFB EGF EGF SEC24B SEC24B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EZH2Histone-lysine N-methyltransferase EZH2 isoform X1. (751 aa)
LMX1ALIM homeobox transcription factor 1-alpha. (382 aa)
SCRIBLOW QUALITY PROTEIN: protein scribble homolog. (1575 aa)
LHX5LIM/homeobox protein Lhx5. (326 aa)
LEF1Lymphoid enhancer-binding factor 1 isoform X1. (414 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
CNTN1Contactin-1 isoform X1. (1018 aa)
EN2Homeobox protein engrailed-like. (331 aa)
KLHL4Kelch-like protein 4 isoform X1. (718 aa)
SHHSonic hedgehog protein. (328 aa)
TTLL1Probable tubulin polyglutamylase TTLL1 isoform X1. (423 aa)
SEZ6Seizure protein 6 homolog. (959 aa)
OPHN1Oligophrenin-1. (797 aa)
CDK5R1Cyclin-dependent kinase 5 activator. (307 aa)
GLI1Zinc finger protein GLI1 isoform X1. (1106 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
TBR1LOW QUALITY PROTEIN: T-box brain protein 1. (642 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
FAIM2Protein lifeguard 2; Belongs to the BI1 family. (316 aa)
GRID2Glutamate receptor ionotropic, delta-2 isoform X1. (1007 aa)
RORANuclear receptor ROR-alpha. (386 aa)
LDB1LIM domain-binding protein 1 isoform X1. (411 aa)
AARSalanine--tRNA ligase, cytoplasmic; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. Belongs to the class-II aminoacyl-tRNA synthetase family. (968 aa)
TTC21BTetratricopeptide repeat protein 21B isoform X1. (1268 aa)
CRKAdapter molecule crk isoform X1. (385 aa)
SKOR2LOW QUALITY PROTEIN: SKI family transcriptional corepressor 2. (693 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
EN1Homeobox protein engrailed-like. (408 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2 isoform X1. (505 aa)
ASCL1LOW QUALITY PROTEIN: achaete-scute homolog 1. (228 aa)
KLHL5Kelch-like protein 5. (708 aa)
PHOX2APaired mesoderm homeobox protein 2A. (253 aa)
PHOX2BPaired mesoderm homeobox protein 2B. (262 aa)
XRCC1DNA repair protein XRCC1. (600 aa)
COQ8BAtypical kinase COQ8B, mitochondrial isoform X1. (527 aa)
ALDH1A2Retinal dehydrogenase 2 isoform X1; Belongs to the aldehyde dehydrogenase family. (526 aa)
NEUROD1Neurogenic differentiation factor. (356 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
ZNF365Protein ZNF365. (408 aa)
LRRC1Leucine-rich repeat-containing protein 1. (443 aa)
PTF1APancreas transcription factor 1 subunit alpha. (310 aa)
GNPATDihydroxyacetone phosphate acyltransferase. (680 aa)
EGR2E3 SUMO-protein ligase EGR2. (472 aa)
NHLH2Helix-loop-helix protein 2. (135 aa)
CRKLCrk-like protein. (303 aa)
SERPINE2Glia-derived nexin; Belongs to the serpin family. (397 aa)
CDK5R2Cyclin-dependent kinase 5 activator. (302 aa)
FZD4Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa)
FAM205ALOW QUALITY PROTEIN: protein FAM205A. (1320 aa)
HSPA5Endoplasmic reticulum chaperone BiP; Belongs to the heat shock protein 70 family. (655 aa)
SMOSmoothened homolog; Belongs to the G-protein coupled receptor Fz/Smo family. (783 aa)
ABL1Tyrosine-protein kinase. (1148 aa)
WHRNWhirlin isoform X1. (919 aa)
NFIBNuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (570 aa)
B4GALT2Beta-1,4-galactosyltransferase 2. (369 aa)
POU4F1POU domain protein. (320 aa)
ARL13BADP-ribosylation factor-like protein 13B. (430 aa)
CBSCystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (562 aa)
AHI1Jouberin isoform X1. (1178 aa)
KDM2BLysine-specific demethylase 2B. (1309 aa)
KCNE1Potassium voltage-gated channel subfamily E member 1. (129 aa)
LHX1LIM/homeobox protein Lhx1. (406 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
PDSS2Decaprenyl-diphosphate synthase subunit 2 isoform X1; Belongs to the FPP/GGPP synthase family. (395 aa)
NANOS1Nanos homolog 1; Belongs to the nanos family. (128 aa)
HOXA2Homeobox protein Hox-A2. (409 aa)
MECP2Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (470 aa)
BCL2Apoptosis regulator Bcl-2 isoform X1. (233 aa)
CDK5Cyclin-dependent-like kinase 5; Belongs to the protein kinase superfamily. (292 aa)
CTNNB1Catenin beta-1. (781 aa)
AGTPBP1Cytosolic carboxypeptidase 1 isoform X1. (1236 aa)
OTX1Homeobox protein OTX1 isoform X1. (355 aa)
GBX2Homeobox protein GBX-2 isoform X1. (348 aa)
HES1Transcription factor HES-1. (280 aa)
PROX1Prospero homeobox protein 1 isoform X1. (737 aa)
PLXNA2plexin-A2. (1894 aa)
ARCN1Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (511 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
NHLH1Helix-loop-helix protein 1. (138 aa)
KIF14Kinesin-like protein KIF14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1639 aa)
REREArginine-glutamic acid dipeptide repeats protein. (1237 aa)
CLP1Polyribonucleotide 5'-hydroxyl-kinase Clp1; Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; thi [...] (444 aa)
SPTBN2Spectrin beta chain; Belongs to the spectrin family. (2397 aa)
CEND1Cell cycle exit and neuronal differentiation protein 1. (146 aa)
KLHL1Kelch-like protein 1 isoform X1. (750 aa)
GBAGlucosylceramidase. (568 aa)
RPGRIP1LProtein fantom. (1269 aa)
CBLN1Cerebellin-1. (193 aa)
GSX2GS homeobox 2. (301 aa)
ZNF423Zinc finger protein 423. (1224 aa)
NAGLUalpha-N-acetylglucosaminidase. (744 aa)
NEUROD2Neurogenic differentiation factor. (382 aa)
LOC112400373LOW QUALITY PROTEIN: protein FAM205A-like. (1336 aa)
PTPRSLOW QUALITY PROTEIN: receptor-type tyrosine-protein phosphatase S. (2076 aa)
HOXB1Homeobox protein Hox-B1. (298 aa)
OGDH2-oxoglutarate dehydrogenase, mitochondrial isoform X3. (1039 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (759 aa)
KAT2AHistone acetyltransferase KAT2A. (872 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (304 aa)
SEZ6L2Seizure 6-like protein 2 isoform X1. (923 aa)
HAP1LOW QUALITY PROTEIN: huntingtin-associated protein 1. (633 aa)
SEMA4Csemaphorin-4C; Belongs to the semaphorin family. (833 aa)
ATRNAttractin isoform X5. (1489 aa)
RBFOX2RNA binding protein fox-1 homolog; RNA-binding protein that regulates alternative splicing events. (428 aa)
HOXB2Homeobox protein Hox-B2. (354 aa)
MAFBTranscription factor MafB. (323 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1238 aa)
SEC24BProtein transport protein Sec24B isoform X1. (1168 aa)
Your Current Organism:
Neophocaena asiaeorientalis
NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise
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