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LOC112396051 LOC112396051 DACT1 DACT1 TRIM21 TRIM21 APP APP TERT TERT USP33 USP33 BMP4 BMP4 GCG GCG VTN VTN RAPGEF2 RAPGEF2 LRP1 LRP1 EP300 EP300 PSEN1 PSEN1 FLOT1 FLOT1 IDE IDE LRRK2 LRRK2 DERL1 DERL1 SPPL3 SPPL3 TRIB3 TRIB3 MAPRE1 MAPRE1 HIPK2 HIPK2 CSF3 CSF3 CTHRC1 CTHRC1 STK4 STK4 PIN1 PIN1 WNT5A WNT5A MMP9 MMP9 PRKN PRKN AKTIP AKTIP PLCL2 PLCL2 LOC112401545 LOC112401545 MEN1 MEN1 BAMBI BAMBI SPTA1 SPTA1 AMFR AMFR HFE HFE TMEM173 TMEM173 NVL NVL ARHGEF7 ARHGEF7 CDK5 CDK5 TCF7L2 TCF7L2 RIPK2 RIPK2 PLXND1 PLXND1 ADD2 ADD2 STK3 STK3 SPON1 SPON1 PLCL1 PLCL1 MARK3 MARK3 CAV1 CAV1 HIP1R HIP1R EPHB6 EPHB6 RALB RALB EPB41L5 EPB41L5 PKD1 PKD1 LOC112409615 LOC112409615 LOC112409616 LOC112409616 RFNG RFNG MFNG MFNG NPHP3 NPHP3 BLK BLK ABL1 ABL1 SPAG8 SPAG8 LFNG LFNG NMD3 NMD3 CLDN5 CLDN5 MAPRE3 MAPRE3 BMP2 BMP2 WNT3A WNT3A KRIT1 KRIT1 EPB41 EPB41 DTX3L DTX3L
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC112396051Probable ubiquitin carboxyl-terminal hydrolase FAF-X isoform X1; Belongs to the peptidase C19 family. (2556 aa)
DACT1Dapper homolog 1. (691 aa)
TRIM21E3 ubiquitin-protein ligase TRIM21. (469 aa)
APPAmyloid-beta A4 protein isoform X1. (767 aa)
TERTTelomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (1136 aa)
USP33Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (910 aa)
BMP4Bone morphogenetic protein 4 isoform X1. (420 aa)
GCGGlucagon isoform X1. (180 aa)
VTNVitronectin. (481 aa)
RAPGEF2Rap guanine nucleotide exchange factor 2. (1744 aa)
LRP1Prolow-density lipoprotein receptor-related protein 1. (4544 aa)
EP300Histone acetyltransferase p300. (2399 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (468 aa)
FLOT1Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (446 aa)
IDEInsulin-degrading enzyme isoform X2; Belongs to the peptidase M16 family. (1019 aa)
LRRK2Leucine-rich repeat serine/threonine-protein kinase 2 isoform X1. (2527 aa)
DERL1Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (309 aa)
SPPL3Signal peptide peptidase-like 3. (384 aa)
TRIB3Tribbles homolog 3. (357 aa)
MAPRE1Microtubule-associated protein RP/EB family member 1. (268 aa)
HIPK2Homeodomain-interacting protein kinase 2. (1027 aa)
CSF3Granulocyte colony-stimulating factor. (195 aa)
CTHRC1Collagen triple helix repeat-containing protein 1. (244 aa)
STK4Serine/threonine-protein kinase 4 isoform X1. (487 aa)
PIN1Peptidyl-prolyl cis-trans isomerase. (163 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
MMP9Matrix metalloproteinase-9. (709 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (465 aa)
AKTIPAKT-interacting protein isoform X1. (293 aa)
PLCL2Phosphoinositide phospholipase C. (1001 aa)
LOC112401545LOW QUALITY PROTEIN: serine/threonine-protein kinase 3-like. (375 aa)
MEN1Menin isoform X1. (616 aa)
BAMBIBMP and activin membrane-bound inhibitor homolog. (218 aa)
SPTA1Spectrin alpha chain, erythrocytic 1. (2408 aa)
AMFRE3 ubiquitin-protein ligase AMFR. (647 aa)
HFEHereditary hemochromatosis protein isoform X1; Belongs to the MHC class I family. (356 aa)
TMEM173Stimulator of interferon genes protein isoform X1. (378 aa)
NVLNuclear valosin-containing protein-like. (848 aa)
ARHGEF7Rho guanine nucleotide exchange factor 7 isoform X1. (705 aa)
CDK5Cyclin-dependent-like kinase 5; Belongs to the protein kinase superfamily. (292 aa)
TCF7L2Transcription factor 7-like 2 isoform X1. (510 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2. (387 aa)
PLXND1plexin-D1. (1847 aa)
ADD2Beta-adducin. (724 aa)
STK3Serine/threonine-protein kinase 3. (491 aa)
SPON1Spondin-1. (807 aa)
PLCL1Phosphoinositide phospholipase C. (1123 aa)
MARK3Non-specific serine/threonine protein kinase. (647 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
HIP1RHuntingtin-interacting protein 1-related protein isoform X1. (1043 aa)
EPHB6Ephrin type-B receptor 6 isoform X1. (1010 aa)
RALBRas-related protein Ral-B isoform X1. (242 aa)
EPB41L5Band 4.1-like protein 5 isoform X1. (746 aa)
PKD1Polycystin-1. (4487 aa)
LOC112409615Probable ubiquitin carboxyl-terminal hydrolase FAF-X. (235 aa)
LOC112409616Probable ubiquitin carboxyl-terminal hydrolase FAF-X; Belongs to the peptidase C19 family. (2060 aa)
RFNGbeta-1,3-N-acetylglucosaminyltransferase radical fringe. (205 aa)
MFNGbeta-1,3-N-acetylglucosaminyltransferase manic fringe isoform X1. (351 aa)
NPHP3Nephrocystin-3 isoform X2. (1234 aa)
BLKTyrosine-protein kinase. (501 aa)
ABL1Tyrosine-protein kinase. (1148 aa)
SPAG8LOW QUALITY PROTEIN: sperm-associated antigen 8. (457 aa)
LFNGbeta-1,3-N-acetylglucosaminyltransferase lunatic fringe. (467 aa)
NMD360S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family. (511 aa)
CLDN5Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (218 aa)
MAPRE3Microtubule-associated protein RP/EB family member 3 isoform X2. (281 aa)
BMP2Bone morphogenetic protein 2 isoform X1. (395 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
KRIT1Krev interaction trapped protein 1 isoform X1. (747 aa)
EPB41Protein 4.1 isoform X7. (1012 aa)
DTX3LE3 ubiquitin-protein ligase DTX3L isoform X2. (738 aa)
Your Current Organism:
Neophocaena asiaeorientalis
NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise
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