STRINGSTRING
PLAG1 PLAG1 PRKAR1A PRKAR1A CER1 CER1 SPRY2 SPRY2 BNC2 BNC2 YAP1 YAP1 HEY2 HEY2 WNT2 WNT2 GATA6 GATA6 LOC112407442 LOC112407442 STK3 STK3 HEG1 HEG1 BCL2 BCL2 LOC112406076 LOC112406076 IFT80 IFT80 FGF9 FGF9 TMEM38B TMEM38B ADPRHL1 ADPRHL1 DDR2 DDR2 RAG2 RAG2 AR AR IL7 IL7 S1PR1 S1PR1 TENM4 TENM4 ANXA6 ANXA6 HLX HLX THBS3 THBS3 FGF7 FGF7 LOC112401545 LOC112401545 ESR1 ESR1 ARX ARX STK4 STK4 DLL1 DLL1 RARA RARA UBE3A UBE3A TBX5 TBX5 SMPD3 SMPD3 SAV1 SAV1 FXN FXN ATF2 ATF2 FGF8 FGF8 ARID2 ARID2 RARG RARG SMAD1 SMAD1 EHMT2 EHMT2 RARB RARB BMP10 BMP10 MAPK11 MAPK11 ZMPSTE24 ZMPSTE24 SHH SHH TGFB2 TGFB2 GJE1 GJE1 NPPC NPPC OSTN OSTN FGF10 FGF10 EXT1 EXT1 PTPN11 PTPN11 EVC EVC CUNH3orf58 CUNH3orf58 MMP13 MMP13 ADRA1A ADRA1A COMP COMP MATN1 MATN1 MESP1 MESP1 ECM1 ECM1 LEPR LEPR ADPRH ADPRH JARID2 JARID2 LOC112411691 LOC112411691 LEP LEP NOTCH1 NOTCH1 SOX9 SOX9
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PLAG1Zinc finger protein PLAG1 isoform X1. (499 aa)
PRKAR1AcAMP-dependent protein kinase type I-alpha regulatory subunit. (380 aa)
CER1Cerberus isoform X1. (273 aa)
SPRY2Protein sprouty homolog 2. (315 aa)
BNC2Zinc finger protein basonuclin-2 isoform X1. (1049 aa)
YAP1Transcriptional coactivator YAP1. (416 aa)
HEY2Hairy/enhancer-of-split related with YRPW motif protein 2. (337 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
GATA6Transcription factor GATA-6. (448 aa)
LOC112407442LOW QUALITY PROTEIN: frataxin, mitochondrial-like. (215 aa)
STK3Serine/threonine-protein kinase 3. (491 aa)
HEG1Protein HEG homolog 1. (1138 aa)
BCL2Apoptosis regulator Bcl-2 isoform X1. (233 aa)
LOC112406076Protein HEG homolog 1-like. (419 aa)
IFT80Intraflagellar transport protein 80 homolog isoform X1. (777 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
TMEM38BTrimeric intracellular cation channel type B isoform X1. (291 aa)
ADPRHL1Protein ADP-ribosylarginine hydrolase-like protein 1. (354 aa)
DDR2Discoidin domain-containing receptor 2. (820 aa)
RAG2V(D)J recombination-activating protein 2. (527 aa)
ARAndrogen receptor isoform X1. (893 aa)
IL7Interleukin-7 isoform X1. (226 aa)
S1PR1Sphingosine 1-phosphate receptor 1; Belongs to the G-protein coupled receptor 1 family. (382 aa)
TENM4Teneurin-4. (2769 aa)
ANXA6Annexin. (673 aa)
HLXH2.0-like homeobox protein. (486 aa)
THBS3Thrombospondin-3 isoform X1. (956 aa)
FGF7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
LOC112401545LOW QUALITY PROTEIN: serine/threonine-protein kinase 3-like. (375 aa)
ESR1Estrogen receptor. (604 aa)
ARXLOW QUALITY PROTEIN: homeobox protein ARX. (445 aa)
STK4Serine/threonine-protein kinase 4 isoform X1. (487 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (759 aa)
RARALOW QUALITY PROTEIN: retinoic acid receptor alpha. (572 aa)
UBE3AUbiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (875 aa)
TBX5T-box transcription factor TBX5. (519 aa)
SMPD3Sphingomyelin phosphodiesterase 3. (653 aa)
SAV1Protein salvador homolog 1. (384 aa)
FXNLOW QUALITY PROTEIN: frataxin, mitochondrial. (244 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2 isoform X1. (505 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
ARID2AT-rich interactive domain-containing protein 2. (1836 aa)
RARGRetinoic acid receptor gamma isoform X2. (458 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
EHMT2Histone-lysine N-methyltransferase EHMT2. (1242 aa)
RARBRetinoic acid receptor beta. (311 aa)
BMP10Bone morphogenetic protein 10. (423 aa)
MAPK11Mitogen-activated protein kinase. (376 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (473 aa)
SHHSonic hedgehog protein. (328 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
GJE1Putative gap junction epsilon-1 protein. (205 aa)
NPPCC-type natriuretic peptide. (127 aa)
OSTNOsteocrin. (132 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
EXT1Exostosin-1; Belongs to the glycosyltransferase 47 family. (746 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
EVCEllis-van Creveld syndrome protein isoform X1. (1032 aa)
CUNH3orf58Deleted in autism protein 1 isoform X1. (430 aa)
MMP13Collagenase 3. (471 aa)
ADRA1Aalpha-1A adrenergic receptor. (466 aa)
COMPCartilage oligomeric matrix protein. (756 aa)
MATN1Cartilage matrix protein. (495 aa)
MESP1Mesoderm posterior protein 1. (265 aa)
ECM1Extracellular matrix protein 1 isoform X1. (544 aa)
LEPRLeptin receptor isoform X1. (1165 aa)
ADPRHADP-ribosylarginine hydrolase. (373 aa)
JARID2Protein Jumonji isoform X1. (1235 aa)
LOC112411691Retinoic acid receptor beta-like. (329 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
NOTCH1LOW QUALITY PROTEIN: neurogenic locus notch homolog protein 1. (2633 aa)
SOX9Transcription factor SOX-9. (486 aa)
Your Current Organism:
Neophocaena asiaeorientalis
NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise
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