STRINGSTRING
PPP1R7 PPP1R7 ROCK1 ROCK1 IKBKB IKBKB FKBP1B FKBP1B GNA12 GNA12 PPP1R11 PPP1R11 PTPRC PTPRC MGAT5 MGAT5 PPP1R26 PPP1R26 TMEM225B TMEM225B PPP1R1B PPP1R1B SRC SRC TIPRL TIPRL PPP1R16B PPP1R16B BOD1L1 BOD1L1 SPPL3 SPPL3 PPP1R42 PPP1R42 PLEK PLEK PPP1R16A PPP1R16A ITGA1 ITGA1 LOC112396079 LOC112396079 ANKLE2 ANKLE2 CSNK2B CSNK2B TGFB2 TGFB2 PPARGC1B PPARGC1B LY6G5B LY6G5B PAWR PAWR PPP6R2 PPP6R2 NCKAP1L NCKAP1L PPP1R17 PPP1R17 PPP1R12A PPP1R12A IFNG IFNG INPP5K INPP5K MASTL MASTL URI1 URI1 MEF2C MEF2C PDGFRB PDGFRB CDH5 CDH5 HSP90B1 HSP90B1 SEMA4D SEMA4D NUAK1 NUAK1 LOC112390413 LOC112390413 MTMR2 MTMR2 LOC112413764 LOC112413764 PPP2R5D PPP2R5D DLC1 DLC1 DEF6 DEF6 IQGAP1 IQGAP1 ENSA ENSA PPP1R8 PPP1R8 MTMR3 MTMR3 PPP1R15A PPP1R15A TGFB1 TGFB1 VRK3 VRK3 SYMPK SYMPK CDCA2 CDCA2 FCRL3 FCRL3 AMBRA1 AMBRA1 CRY2 CRY2 PPP6R3 PPP6R3 LOC112401535 LOC112401535 LOC112408725 LOC112408725 GBA GBA CNEP1R1 CNEP1R1 LRRC49 LRRC49 LRRC46 LRRC46 MTMR9 MTMR9 TMEM132D TMEM132D LOC112410324 LOC112410324 PPP4R4 PPP4R4 TMEM132C TMEM132C LRRC43 LRRC43 SWAP70 SWAP70 SMPD1 SMPD1 IGBP1 IGBP1 CMYA5 CMYA5 ARPP19 ARPP19 PPP6R1 PPP6R1 RIPK3 RIPK3 NPNT NPNT BOD1 BOD1 PPP1R2 PPP1R2 GPLD1 GPLD1 PPP1R15B PPP1R15B PPP2R5A PPP2R5A PPP1R36 PPP1R36 PINK1 PINK1 HTT HTT TSC1 TSC1 CHP2 CHP2 TMEM130 TMEM130 PRKCD PRKCD STYXL1 STYXL1 PPP1R35 PPP1R35 CDK5RAP3 CDK5RAP3 YWHAB YWHAB LOC112400497 LOC112400497 BMP2 BMP2 MFHAS1 MFHAS1 BAG4 BAG4 PTPA PTPA PPP2R3C PPP2R3C
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PPP1R7Protein phosphatase 1 regulatory subunit 7 isoform X1. (364 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1354 aa)
IKBKBInhibitor of nuclear factor kappa-B kinase subunit beta isoform X1. (821 aa)
FKBP1BPeptidylprolyl isomerase. (80 aa)
GNA12Guanine nucleotide-binding protein subunit alpha-12. (305 aa)
PPP1R11E3 ubiquitin-protein ligase PPP1R11. (126 aa)
PTPRCReceptor-type tyrosine-protein phosphatase C isoform X1. (1258 aa)
MGAT5Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A. (741 aa)
PPP1R26Protein phosphatase 1 regulatory subunit 26. (1188 aa)
TMEM225BTransmembrane protein 225B isoform X1. (286 aa)
PPP1R1BProtein phosphatase 1 regulatory subunit 1B isoform X1. (177 aa)
SRCTyrosine-protein kinase. (601 aa)
TIPRLTIP41-like protein isoform X1. (272 aa)
PPP1R16BProtein phosphatase 1 regulatory inhibitor subunit 16B. (568 aa)
BOD1L1Biorientation of chromosomes in cell division protein 1-like 1. (2868 aa)
SPPL3Signal peptide peptidase-like 3. (384 aa)
PPP1R42Protein phosphatase 1 regulatory subunit 42. (271 aa)
PLEKPleckstrin. (350 aa)
PPP1R16AProtein phosphatase 1 regulatory subunit 16A. (490 aa)
ITGA1Integrin alpha-1; Belongs to the integrin alpha chain family. (1178 aa)
LOC112396079cAMP-regulated phosphoprotein 19; Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. Belongs to the endosulfine family. (112 aa)
ANKLE2Ankyrin repeat and LEM domain-containing protein 2. (880 aa)
CSNK2BCasein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (215 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
PPARGC1BPeroxisome proliferator-activated receptor gamma coactivator 1-beta isoform X1. (1019 aa)
LY6G5BLymphocyte antigen 6 complex locus protein G5b. (197 aa)
PAWRPRKC apoptosis WT1 regulator protein. (183 aa)
PPP6R2Serine/threonine-protein phosphatase 6 regulatory subunit 2 isoform X1. (957 aa)
NCKAP1LNck-associated protein 1-like isoform X1. (1156 aa)
PPP1R17Protein phosphatase 1 regulatory subunit 17. (152 aa)
PPP1R12AProtein phosphatase 1 regulatory subunit. (1030 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa)
INPP5KInositol polyphosphate 5-phosphatase K isoform X3. (476 aa)
MASTLSerine/threonine-protein kinase greatwall isoform X3. (887 aa)
URI1Unconventional prefoldin RPB5 interactor 1. (529 aa)
MEF2CMyocyte-specific enhancer factor 2C isoform X4. (483 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1103 aa)
CDH5Cadherin-5; Cadherins are calcium-dependent cell adhesion proteins. (782 aa)
HSP90B1Endoplasmin. (805 aa)
SEMA4Dsemaphorin-4D; Belongs to the semaphorin family. (863 aa)
NUAK1NUAK family SNF1-like kinase 1. (680 aa)
LOC112390413Uncharacterized protein LOC112390413 isoform X1. (470 aa)
MTMR2Myotubularin-related protein 2 isoform X1. (643 aa)
LOC112413764LOW QUALITY PROTEIN: serine/threonine-protein phosphatase 6 regulatory subunit 2-like. (615 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (602 aa)
DLC1Rho GTPase-activating protein 7 isoform X1. (1528 aa)
DEF6Differentially expressed in FDCP 6 homolog isoform X1. (673 aa)
IQGAP1Ras GTPase-activating-like protein IQGAP1. (1657 aa)
ENSAAlpha-endosulfine; Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. Belongs to the endosulfine family. (121 aa)
PPP1R8Nuclear inhibitor of protein phosphatase 1. (378 aa)
MTMR3Myotubularin-related protein 3 isoform X1. (1202 aa)
PPP1R15ALOW QUALITY PROTEIN: protein phosphatase 1 regulatory subunit 15A. (568 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa)
VRK3Inactive serine/threonine-protein kinase VRK3. (435 aa)
SYMPKSymplekin. (1275 aa)
CDCA2Cell division cycle-associated protein 2. (1013 aa)
FCRL3Fc receptor-like protein 3 isoform X1. (726 aa)
AMBRA1Activating molecule in BECN1-regulated autophagy protein 1 isoform X2. (1295 aa)
CRY2Cryptochrome-2 isoform X1. (638 aa)
PPP6R3Serine/threonine-protein phosphatase 6 regulatory subunit 3 isoform X1. (875 aa)
LOC112401535Immunoglobulin-binding protein 1-like isoform X1. (372 aa)
LOC112408725Transmembrane protein 132B. (1065 aa)
GBAGlucosylceramidase. (568 aa)
CNEP1R1Nuclear envelope phosphatase-regulatory subunit 1. (125 aa)
LRRC49Leucine-rich repeat-containing protein 49. (685 aa)
LRRC46Leucine-rich repeat-containing protein 46. (323 aa)
MTMR9Myotubularin-related protein 9. (324 aa)
TMEM132DTransmembrane protein 132D. (1094 aa)
LOC112410324CMRF35-like molecule 8 isoform X1. (378 aa)
PPP4R4Serine/threonine-protein phosphatase 4 regulatory subunit 4. (872 aa)
TMEM132CTransmembrane protein 132C. (597 aa)
LRRC43Leucine-rich repeat-containing protein 43. (544 aa)
SWAP70Switch-associated protein 70 isoform X1. (585 aa)
SMPD1Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (625 aa)
IGBP1Immunoglobulin-binding protein 1. (368 aa)
CMYA5Cardiomyopathy-associated protein 5. (3944 aa)
ARPP19cAMP-regulated phosphoprotein 19; Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. Belongs to the endosulfine family. (96 aa)
PPP6R1LOW QUALITY PROTEIN: serine/threonine-protein phosphatase 6 regulatory subunit 1. (892 aa)
RIPK3LOW QUALITY PROTEIN: receptor-interacting serine/threonine-protein kinase 3. (518 aa)
NPNTNephronectin isoform X1. (581 aa)
BOD1Biorientation of chromosomes in cell division protein 1 isoform X1. (206 aa)
PPP1R2Protein phosphatase inhibitor 2. (206 aa)
GPLD1Phosphatidylinositol-glycan-specific phospholipase D. (849 aa)
PPP1R15BProtein phosphatase 1 regulatory subunit 15B isoform X1. (785 aa)
PPP2R5ASerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (488 aa)
PPP1R36LOW QUALITY PROTEIN: protein phosphatase 1 regulatory subunit 36. (437 aa)
PINK1Serine/threonine-protein kinase PINK1, mitochondrial isoform X1. (530 aa)
HTTHuntingtin. (3165 aa)
TSC1Hamartin isoform X1. (1169 aa)
CHP2Calcineurin B homologous protein 2. (196 aa)
TMEM130Transmembrane protein 130. (445 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (675 aa)
STYXL1Serine/threonine/tyrosine-interacting-like protein 1 isoform X1. (313 aa)
PPP1R35LOW QUALITY PROTEIN: protein phosphatase 1 regulatory subunit 35. (360 aa)
CDK5RAP3CDK5 regulatory subunit-associated protein 3 isoform X1. (538 aa)
YWHAB14-3-3 protein beta/alpha; Belongs to the 14-3-3 family. (246 aa)
LOC112400497Myotubularin-related protein 9-like. (225 aa)
BMP2Bone morphogenetic protein 2 isoform X1. (395 aa)
MFHAS1Malignant fibrous histiocytoma-amplified sequence 1 isoform X1. (1052 aa)
BAG4BAG family molecular chaperone regulator 4 isoform X1. (459 aa)
PTPASerine/threonine-protein phosphatase 2A activator; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. (352 aa)
PPP2R3CSerine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma isoform X1. (453 aa)
Your Current Organism:
Neophocaena asiaeorientalis
NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise
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