STRINGSTRING
LRRC46 LRRC46 MTMR9 MTMR9 LOC112400497 LOC112400497 PRKCD PRKCD TMEM130 TMEM130 CHP2 CHP2 SRC SRC PPP1R16B PPP1R16B SPPL3 SPPL3 PPP1R42 PPP1R42 PLEK PLEK PTPA PTPA PTPRC PTPRC GNA12 GNA12 PINK1 PINK1 PDGFRB PDGFRB MEF2C MEF2C IFNG IFNG PPP1R12A PPP1R12A PAWR PAWR PPARGC1B PPARGC1B ANKLE2 ANKLE2 ITGA1 ITGA1 CDH5 CDH5 LRRC49 LRRC49 LOC112410324 LOC112410324 LRRC43 LRRC43 PPP1R7 PPP1R7 ROCK1 ROCK1 SMPD1 SMPD1 RIPK3 RIPK3 NPNT NPNT GPLD1 GPLD1 BMP2 BMP2 PPP2R5D PPP2R5D DLC1 DLC1 PPP1R15A PPP1R15A TGFB1 TGFB1 VRK3 VRK3 SYMPK SYMPK CDCA2 CDCA2 PPP1R15B PPP1R15B PPP2R5A PPP2R5A FCRL3 FCRL3 CNEP1R1 CNEP1R1 GBA GBA AMBRA1 AMBRA1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LRRC46Leucine-rich repeat-containing protein 46. (323 aa)
MTMR9Myotubularin-related protein 9. (324 aa)
LOC112400497Myotubularin-related protein 9-like. (225 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (675 aa)
TMEM130Transmembrane protein 130. (445 aa)
CHP2Calcineurin B homologous protein 2. (196 aa)
SRCTyrosine-protein kinase. (601 aa)
PPP1R16BProtein phosphatase 1 regulatory inhibitor subunit 16B. (568 aa)
SPPL3Signal peptide peptidase-like 3. (384 aa)
PPP1R42Protein phosphatase 1 regulatory subunit 42. (271 aa)
PLEKPleckstrin. (350 aa)
PTPASerine/threonine-protein phosphatase 2A activator; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. (352 aa)
PTPRCReceptor-type tyrosine-protein phosphatase C isoform X1. (1258 aa)
GNA12Guanine nucleotide-binding protein subunit alpha-12. (305 aa)
PINK1Serine/threonine-protein kinase PINK1, mitochondrial isoform X1. (530 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1103 aa)
MEF2CMyocyte-specific enhancer factor 2C isoform X4. (483 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa)
PPP1R12AProtein phosphatase 1 regulatory subunit. (1030 aa)
PAWRPRKC apoptosis WT1 regulator protein. (183 aa)
PPARGC1BPeroxisome proliferator-activated receptor gamma coactivator 1-beta isoform X1. (1019 aa)
ANKLE2Ankyrin repeat and LEM domain-containing protein 2. (880 aa)
ITGA1Integrin alpha-1; Belongs to the integrin alpha chain family. (1178 aa)
CDH5Cadherin-5; Cadherins are calcium-dependent cell adhesion proteins. (782 aa)
LRRC49Leucine-rich repeat-containing protein 49. (685 aa)
LOC112410324CMRF35-like molecule 8 isoform X1. (378 aa)
LRRC43Leucine-rich repeat-containing protein 43. (544 aa)
PPP1R7Protein phosphatase 1 regulatory subunit 7 isoform X1. (364 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1354 aa)
SMPD1Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (625 aa)
RIPK3LOW QUALITY PROTEIN: receptor-interacting serine/threonine-protein kinase 3. (518 aa)
NPNTNephronectin isoform X1. (581 aa)
GPLD1Phosphatidylinositol-glycan-specific phospholipase D. (849 aa)
BMP2Bone morphogenetic protein 2 isoform X1. (395 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (602 aa)
DLC1Rho GTPase-activating protein 7 isoform X1. (1528 aa)
PPP1R15ALOW QUALITY PROTEIN: protein phosphatase 1 regulatory subunit 15A. (568 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa)
VRK3Inactive serine/threonine-protein kinase VRK3. (435 aa)
SYMPKSymplekin. (1275 aa)
CDCA2Cell division cycle-associated protein 2. (1013 aa)
PPP1R15BProtein phosphatase 1 regulatory subunit 15B isoform X1. (785 aa)
PPP2R5ASerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (488 aa)
FCRL3Fc receptor-like protein 3 isoform X1. (726 aa)
CNEP1R1Nuclear envelope phosphatase-regulatory subunit 1. (125 aa)
GBAGlucosylceramidase. (568 aa)
AMBRA1Activating molecule in BECN1-regulated autophagy protein 1 isoform X2. (1295 aa)
Your Current Organism:
Neophocaena asiaeorientalis
NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise
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