STRINGSTRING
LRRC1 LRRC1 FZD3 FZD3 TP63 TP63 CHST11 CHST11 SCRIB SCRIB TCF15 TCF15 TBXT TBXT WNT5A WNT5A HES7 HES7 EPHA2 EPHA2 DCHS1 DCHS1 LOC112407979 LOC112407979 MED12 MED12 LOC112407988 LOC112407988 AXIN1 AXIN1 WNT3A WNT3A SP5 SP5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LRRC1Leucine-rich repeat-containing protein 1. (443 aa)
FZD3Frizzled-3; Belongs to the G-protein coupled receptor Fz/Smo family. (468 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa)
CHST11Carbohydrate sulfotransferase. (418 aa)
SCRIBLOW QUALITY PROTEIN: protein scribble homolog. (1575 aa)
TCF15Transcription factor 15. (229 aa)
TBXTBrachyury protein isoform X1. (435 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
HES7Transcription factor HES-7. (171 aa)
EPHA2Ephrin type-A receptor 2. (975 aa)
DCHS1Protocadherin-16. (3294 aa)
LOC112407979Secreted frizzled-related protein 2-like. (105 aa)
MED12Mediator of RNA polymerase II transcription subunit 12. (2097 aa)
LOC112407988Secreted frizzled-related protein 2. (294 aa)
AXIN1Axin-1 isoform X1. (866 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
SP5Transcription factor Sp5. (399 aa)
Your Current Organism:
Neophocaena asiaeorientalis
NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise
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