STRINGSTRING
NPTN NPTN PRKD2 PRKD2 FUZ FUZ RUNX2 RUNX2 GPC1 GPC1 SPRY2 SPRY2 NOG NOG SHISA2 SHISA2 CTNNB1 CTNNB1 SPRY3 SPRY3 SPRY4 SPRY4 DSTYK DSTYK CREB3L1 CREB3L1 SULF2 SULF2 WNT5A WNT5A SPRY1 SPRY1 NGFR NGFR LRIT3 LRIT3 FGFBP3 FGFBP3 SULF1 SULF1 PRDM14 PRDM14 HHIP HHIP THBS1 THBS1 GATA3 GATA3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NPTNNeuroplastin. (415 aa)
PRKD2LOW QUALITY PROTEIN: serine/threonine-protein kinase D2. (806 aa)
FUZProtein fuzzy homolog isoform X1. (440 aa)
RUNX2Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (408 aa)
GPC1LOW QUALITY PROTEIN: glypican-1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (527 aa)
SPRY2Protein sprouty homolog 2. (315 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
SHISA2Protein shisa-2 homolog. (294 aa)
CTNNB1Catenin beta-1. (781 aa)
SPRY3Protein sprouty homolog 3. (288 aa)
SPRY4Protein sprouty homolog 4. (299 aa)
DSTYKDual serine/threonine and tyrosine protein kinase isoform X1. (929 aa)
CREB3L1Cyclic AMP-responsive element-binding protein 3-like protein 1. (520 aa)
SULF2Extracellular sulfatase Sulf-2. (865 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
SPRY1Protein sprouty homolog 1. (319 aa)
NGFRTumor necrosis factor receptor superfamily member 16. (427 aa)
LRIT3Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 3. (672 aa)
FGFBP3Fibroblast growth factor-binding protein 3. (257 aa)
SULF1Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family. (882 aa)
PRDM14PR domain zinc finger protein 14. (571 aa)
HHIPHedgehog-interacting protein. (700 aa)
THBS1Thrombospondin-1. (1170 aa)
GATA3Trans-acting T-cell-specific transcription factor GATA-3 isoform X1. (444 aa)
Your Current Organism:
Neophocaena asiaeorientalis
NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise
Server load: low (28%) [HD]