node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CTNNB1 | NOG | A0A341C5R9 | A0A341CFJ8 | Catenin beta-1. | Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. | 0.597 |
CTNNB1 | RUNX2 | A0A341C5R9 | A0A341D3Q3 | Catenin beta-1. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.869 |
CTNNB1 | THBS1 | A0A341C5R9 | A0A341AE57 | Catenin beta-1. | Thrombospondin-1. | 0.408 |
CTNNB1 | WNT5A | A0A341C5R9 | A0A341BKG2 | Catenin beta-1. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.810 |
GATA3 | RUNX2 | A0A341ABP1 | A0A341D3Q3 | Trans-acting T-cell-specific transcription factor GATA-3 isoform X1. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.653 |
HHIP | NGFR | A0A341ARR8 | A0A341BCJ4 | Hedgehog-interacting protein. | Tumor necrosis factor receptor superfamily member 16. | 0.446 |
NGFR | HHIP | A0A341BCJ4 | A0A341ARR8 | Tumor necrosis factor receptor superfamily member 16. | Hedgehog-interacting protein. | 0.446 |
NOG | CTNNB1 | A0A341CFJ8 | A0A341C5R9 | Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. | Catenin beta-1. | 0.597 |
NOG | RUNX2 | A0A341CFJ8 | A0A341D3Q3 | Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.449 |
RUNX2 | CTNNB1 | A0A341D3Q3 | A0A341C5R9 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | Catenin beta-1. | 0.869 |
RUNX2 | GATA3 | A0A341D3Q3 | A0A341ABP1 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | Trans-acting T-cell-specific transcription factor GATA-3 isoform X1. | 0.653 |
RUNX2 | NOG | A0A341D3Q3 | A0A341CFJ8 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. | 0.449 |
RUNX2 | WNT5A | A0A341D3Q3 | A0A341BKG2 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.487 |
SPRY1 | SPRY2 | A0A341BGX5 | A0A341CN76 | Protein sprouty homolog 1. | Protein sprouty homolog 2. | 0.632 |
SPRY1 | SPRY3 | A0A341BGX5 | A0A341C4H1 | Protein sprouty homolog 1. | Protein sprouty homolog 3. | 0.550 |
SPRY1 | SPRY4 | A0A341BGX5 | A0A341C024 | Protein sprouty homolog 1. | Protein sprouty homolog 4. | 0.555 |
SPRY2 | SPRY1 | A0A341CN76 | A0A341BGX5 | Protein sprouty homolog 2. | Protein sprouty homolog 1. | 0.632 |
SPRY3 | SPRY1 | A0A341C4H1 | A0A341BGX5 | Protein sprouty homolog 3. | Protein sprouty homolog 1. | 0.550 |
SPRY4 | SPRY1 | A0A341C024 | A0A341BGX5 | Protein sprouty homolog 4. | Protein sprouty homolog 1. | 0.555 |
THBS1 | CTNNB1 | A0A341AE57 | A0A341C5R9 | Thrombospondin-1. | Catenin beta-1. | 0.408 |