STRINGSTRING
MYBBP1A MYBBP1A SESN2 SESN2 SIRT1 SIRT1 PRKAG3 PRKAG3 HSPA5 HSPA5 PICK1 PICK1 PIK3C3 PIK3C3 SIK1 SIK1 IMPACT IMPACT RRP8 RRP8 PRKAA2 PRKAA2 BECN1 BECN1 BHLHA15 BHLHA15 EIF2AK3 EIF2AK3 PMAIP1 PMAIP1 FOXO3 FOXO3 SESN1 SESN1 BCL2 BCL2 NIM1K NIM1K ZC3H12A ZC3H12A PRKAA1 PRKAA1 PRKAG2 PRKAG2 SIK2 SIK2 NUAK2 NUAK2 KAT5 KAT5 TBL2 TBL2 PLIN2 PLIN2 PLIN3 PLIN3 ATF4 ATF4 SZT2 SZT2 SLC2A1 SLC2A1 CUNH12orf66 CUNH12orf66 ASNS ASNS MTMR3 MTMR3 SH3GLB1 SH3GLB1 SESN3 SESN3 NUAK1 NUAK1 KPTN KPTN XBP1 XBP1 ITFG2 ITFG2 NFE2L2 NFE2L2 ATG14 ATG14 PRKAG1 PRKAG1 SUV39H1 SUV39H1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MYBBP1ALOW QUALITY PROTEIN: myb-binding protein 1A. (1407 aa)
SESN2Sestrin-2. (471 aa)
SIRT1NAD-dependent protein deacetylase sirtuin-1 isoform X1. (557 aa)
PRKAG35'-AMP-activated protein kinase subunit gamma-3. (464 aa)
HSPA5Endoplasmic reticulum chaperone BiP; Belongs to the heat shock protein 70 family. (655 aa)
PICK1PRKCA-binding protein. (417 aa)
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3. (900 aa)
SIK1Serine/threonine-protein kinase SIK1. (657 aa)
IMPACTProtein IMPACT isoform X1. (318 aa)
RRP8Ribosomal RNA-processing protein 8; Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone- modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and pr [...] (468 aa)
PRKAA2Non-specific serine/threonine protein kinase. (462 aa)
BECN1Beclin-1 isoform X1. (471 aa)
BHLHA15Class A basic helix-loop-helix protein 15. (215 aa)
EIF2AK3Eukaryotic translation initiation factor 2-alpha kinase 3 isoform X1. (1128 aa)
PMAIP1Phorbol-12-myristate-13-acetate-induced protein 1. (54 aa)
FOXO3Forkhead box protein O3. (672 aa)
SESN1Sestrin-1 isoform X1. (551 aa)
BCL2Apoptosis regulator Bcl-2 isoform X1. (233 aa)
NIM1KSerine/threonine-protein kinase NIM1; Belongs to the protein kinase superfamily. (436 aa)
ZC3H12AEndoribonuclease ZC3H12A. (583 aa)
PRKAA1Non-specific serine/threonine protein kinase. (559 aa)
PRKAG25'-AMP-activated protein kinase subunit gamma-2 isoform X1. (566 aa)
SIK2Serine/threonine-protein kinase SIK2 isoform X1. (906 aa)
NUAK2NUAK family SNF1-like kinase 2. (633 aa)
KAT5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (546 aa)
TBL2Transducin beta-like protein 2. (446 aa)
PLIN2Perilipin; Belongs to the perilipin family. (455 aa)
PLIN3Perilipin; Belongs to the perilipin family. (438 aa)
ATF4Cyclic AMP-dependent transcription factor ATF-4. (350 aa)
SZT2KICSTOR complex protein SZT2 isoform X1. (3434 aa)
SLC2A1Solute carrier family 2, facilitated glucose transporter member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (492 aa)
CUNH12orf66KICSTOR complex protein C12orf66 homolog. (445 aa)
ASNSAsparagine synthetase [glutamine-hydrolyzing]. (561 aa)
MTMR3Myotubularin-related protein 3 isoform X1. (1202 aa)
SH3GLB1endophilin-B1. (365 aa)
SESN3Sestrin-3. (414 aa)
NUAK1NUAK family SNF1-like kinase 1. (680 aa)
KPTNKICSTOR complex protein kaptin. (435 aa)
XBP1LOW QUALITY PROTEIN: X-box-binding protein 1. (379 aa)
ITFG2KICSTOR complex protein ITFG2. (444 aa)
NFE2L2Nuclear factor erythroid 2-related factor 2 isoform X1. (622 aa)
ATG14Beclin 1-associated autophagy-related key regulator. (492 aa)
PRKAG15'-AMP-activated protein kinase subunit gamma-1 isoform X1. (333 aa)
SUV39H1Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily. (419 aa)
Your Current Organism:
Neophocaena asiaeorientalis
NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise
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