STRINGSTRING
RPS3 RPS3 ALOX12 ALOX12 EPHA7 EPHA7 CASP8AP2 CASP8AP2 PDCD6 PDCD6 NLE1 NLE1 LOC112390536 LOC112390536 SYK SYK FASLG FASLG XDH XDH THBS1 THBS1 LOC112391834 LOC112391834 BID BID LOC112392090 LOC112392090 NLRC4 NLRC4 F2R F2R CD27 CD27 ATP2A3 ATP2A3 LOC112391536 LOC112391536 ANP32B ANP32B PDCD5 PDCD5 P2RX1 P2RX1 LOC112392028 LOC112392028 SMAD3 SMAD3 IFT57 IFT57 NOL3 NOL3 PAX2 PAX2 ACVR1C ACVR1C NR4A1 NR4A1 GRAMD4 GRAMD4 SENP1 SENP1 DHCR24 DHCR24 RPS6KA3 RPS6KA3 LOC112396076 LOC112396076 TNFSF10 TNFSF10 ROBO1 ROBO1 COL4A3 COL4A3 LAMTOR5 LAMTOR5 FNIP1 FNIP1 MYC MYC CSNK2A1 CSNK2A1 EGLN3 EGLN3 TNFAIP8 TNFAIP8 SRC SRC BCL2L11 BCL2L11 CTSH CTSH LOC112398466 LOC112398466 LOC112399310 LOC112399310 FAS FAS NGFR NGFR FIS1 FIS1 HIP1 HIP1 LOC112399406 LOC112399406 PDCD2 PDCD2 PRR7 PRR7 TNFSF14 TNFSF14 CDKN2D CDKN2D XIAP XIAP REST REST NKX3-1 NKX3-1 MMP9 MMP9 SOX7 SOX7 ACER2 ACER2 LOC112401122 LOC112401122 LOC112401809 LOC112401809 UACA UACA PRDX5 PRDX5 S100A8 S100A8 PIDD1 PIDD1 TP63 TP63 PIH1D1 PIH1D1 BBC3 BBC3 PLAUR PLAUR SIAH2 SIAH2 RFFL RFFL BAX BAX FAM162A FAM162A LOC112401967 LOC112401967 PARK7 PARK7 CASP9 CASP9 BIRC7 BIRC7 BAD BAD MUL1 MUL1 SH3RF1 SH3RF1 FOXL2 FOXL2 PTGS2 PTGS2 MGMT MGMT F3 F3 DELE1 DELE1 PAK2 PAK2 HGF HGF CD44 CD44 GAS6 GAS6 LOC112404902 LOC112404902 CRYAB CRYAB DAPK1 DAPK1 MALT1 MALT1 AQP1 AQP1 CRADD CRADD CAAP1 CAAP1 MICAL1 MICAL1 PMAIP1 PMAIP1 NOD1 NOD1 PRDX3 PRDX3 NAIP NAIP BCAP31 BCAP31 USP47 USP47 CASP8 CASP8 CFLAR CFLAR LOC112407979 LOC112407979 CASP10 CASP10 CASP2 CASP2 LOC112407988 LOC112407988 DIABLO DIABLO HIP1R HIP1R RNF34 RNF34 AIFM1 AIFM1 APAF1 APAF1 MAP3K5 MAP3K5 DDX3X DDX3X TFAP4 TFAP4 BIRC3 BIRC3 BIRC2 BIRC2 BOK BOK BIRC5 BIRC5 PML PML GSN GSN TNFSF15 TNFSF15 CARD9 CARD9 VIL1 VIL1 GPER1 GPER1 PPM1F PPM1F INTS1 INTS1 HTRA2 HTRA2 WNT3A WNT3A DLC1 DLC1 MTCH1 MTCH1 BAK1 BAK1 SIRT1 SIRT1 RPS6KA1 RPS6KA1 NODAL NODAL LAPTM5 LAPTM5 LCK LCK SFN SFN DAP DAP YJEFN3 YJEFN3 BCL10 BCL10 NDUFA13 NDUFA13 CYR61 CYR61 RACK1 RACK1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RPS340S ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (243 aa)
ALOX12Arachidonate 12-lipoxygenase, 12S-type. (663 aa)
EPHA7Ephrin type-A receptor 7. (1006 aa)
CASP8AP2CASP8-associated protein 2 isoform X1. (1973 aa)
PDCD6Programmed cell death protein 6 isoform X1. (189 aa)
NLE1Notchless protein homolog 1. (485 aa)
LOC112390536LOW QUALITY PROTEIN: NACHT, LRR and PYD domains-containing protein 12-like. (176 aa)
SYKTyrosine-protein kinase. (626 aa)
FASLGTumor necrosis factor ligand superfamily member 6; Belongs to the tumor necrosis factor family. (262 aa)
XDHXanthine dehydrogenase/oxidase isoform X1. (1334 aa)
THBS1Thrombospondin-1. (1170 aa)
LOC112391834C-type lectin domain family 7 member A-like isoform X1. (244 aa)
BIDBH3-interacting domain death agonist isoform X1. (326 aa)
LOC112392090NACHT, LRR and PYD domains-containing protein 3-like. (582 aa)
NLRC4NLR family CARD domain-containing protein 4 isoform X1. (1024 aa)
F2RProteinase-activated receptor 1; Belongs to the G-protein coupled receptor 1 family. (427 aa)
CD27CD27 antigen. (251 aa)
ATP2A3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1057 aa)
LOC112391536Cytochrome c 2; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
ANP32BAcidic leucine-rich nuclear phosphoprotein 32 family member B. (261 aa)
PDCD5Programmed cell death protein 5. (125 aa)
P2RX1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (512 aa)
LOC112392028RE1-silencing transcription factor-like. (305 aa)
SMAD3Mothers against decapentaplegic homolog. (376 aa)
IFT57Intraflagellar transport protein 57 homolog. (427 aa)
NOL3Nucleolar protein 3. (202 aa)
PAX2Paired box protein Pax-2 isoform X1. (521 aa)
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (493 aa)
NR4A1Nuclear receptor subfamily 4 group A member 1. (593 aa)
GRAMD4GRAM domain-containing protein 4. (843 aa)
SENP1Sentrin-specific protease 1 isoform X1. (690 aa)
DHCR24Delta(24)-sterol reductase. (516 aa)
RPS6KA3Ribosomal protein S6 kinase. (733 aa)
LOC112396076ATP-dependent RNA helicase DDX3X-like; Belongs to the DEAD box helicase family. (656 aa)
TNFSF10Tumor necrosis factor ligand superfamily member. (288 aa)
ROBO1Roundabout homolog 1. (1613 aa)
COL4A3Collagen alpha-3(IV) chain isoform X1. (1674 aa)
LAMTOR5Ragulator complex protein LAMTOR5. (91 aa)
FNIP1Folliculin-interacting protein 1 isoform X1. (1165 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (439 aa)
CSNK2A1Casein kinase II subunit alpha; Belongs to the protein kinase superfamily. (391 aa)
EGLN3Egl nine homolog 3. (239 aa)
TNFAIP8Tumor necrosis factor alpha-induced protein 8 isoform X1. (212 aa)
SRCTyrosine-protein kinase. (601 aa)
BCL2L11Bcl-2-like protein 11; Induces apoptosis and anoikis. Belongs to the Bcl-2 family. (196 aa)
CTSHPro-cathepsin H; Belongs to the peptidase C1 family. (297 aa)
LOC112398466Vasopressin-neurophysin 2-copeptin-like; Belongs to the vasopressin/oxytocin family. (200 aa)
LOC112399310Apoptosis-associated speck-like protein containing a CARD isoform X1. (195 aa)
FASTumor necrosis factor receptor superfamily member 6 isoform X1. (334 aa)
NGFRTumor necrosis factor receptor superfamily member 16. (427 aa)
FIS1Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. (152 aa)
HIP1LOW QUALITY PROTEIN: huntingtin-interacting protein 1. (106 aa)
LOC112399406Apoptosis-associated speck-like protein containing a CARD isoform X1. (191 aa)
PDCD2Programmed cell death protein 2 isoform X1. (344 aa)
PRR7Proline-rich protein 7. (269 aa)
TNFSF14Tumor necrosis factor ligand superfamily member 14 isoform X1; Belongs to the tumor necrosis factor family. (311 aa)
CDKN2DCyclin-dependent kinase 4 inhibitor D. (166 aa)
XIAPE3 ubiquitin-protein ligase XIAP isoform X1. (523 aa)
RESTRE1-silencing transcription factor isoform X2. (450 aa)
NKX3-1Homeobox protein Nkx-3.1. (241 aa)
MMP9Matrix metalloproteinase-9. (709 aa)
SOX7Transcription factor SOX-7. (320 aa)
ACER2Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (275 aa)
LOC112401122Huntingtin-interacting protein 1. (914 aa)
LOC112401809Protein S100-A9-like; Belongs to the S-100 family. (128 aa)
UACAUveal autoantigen with coiled-coil domains and ankyrin repeats isoform X1. (1415 aa)
PRDX5Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (219 aa)
S100A8Protein S100; Belongs to the S-100 family. (89 aa)
PIDD1P53-induced death domain-containing protein 1. (914 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa)
PIH1D1PIH1 domain-containing protein 1 isoform X2. (296 aa)
BBC3LOW QUALITY PROTEIN: bcl-2-binding component 3. (201 aa)
PLAURUrokinase plasminogen activator surface receptor isoform X1. (331 aa)
SIAH2E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (198 aa)
RFFLE3 ubiquitin-protein ligase rififylin isoform X1. (393 aa)
BAXApoptosis regulator BAX. (192 aa)
FAM162AProtein FAM162A isoform X1. (183 aa)
LOC112401967Ribonuclease inhibitor-like. (428 aa)
PARK7Protein/nucleic acid deglycase DJ-1. (189 aa)
CASP9Caspase-9; Belongs to the peptidase C14A family. (442 aa)
BIRC7Baculoviral IAP repeat-containing protein 7. (443 aa)
BADBcl2-associated agonist of cell death. (168 aa)
MUL1Mitochondrial ubiquitin ligase activator of NFKB 1. (352 aa)
SH3RF1E3 ubiquitin-protein ligase SH3RF1. (712 aa)
FOXL2LOW QUALITY PROTEIN: forkhead box protein L2. (191 aa)
PTGS2Prostaglandin G/H synthase 2. (604 aa)
MGMTmethylated-DNA--protein-cysteine methyltransferase isoform X2. (282 aa)
F3Tissue factor. (297 aa)
DELE1Death ligand signal enhancer isoform X1. (540 aa)
PAK2Non-specific serine/threonine protein kinase. (523 aa)
HGFHepatocyte growth factor isoform X1; Belongs to the peptidase S1 family. (734 aa)
CD44CD44 antigen isoform X15. (783 aa)
GAS6Growth arrest-specific protein 6. (540 aa)
LOC112404902LOW QUALITY PROTEIN: baculoviral IAP repeat-containing protein 5-like. (215 aa)
CRYABAlpha-crystallin B chain; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. (175 aa)
DAPK1Death-associated protein kinase 1 isoform X1. (1440 aa)
MALT1Mucosa-associated lymphoid tissue lymphoma translocation protein 1. (832 aa)
AQP1Aquaporin-1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (271 aa)
CRADDDeath domain-containing protein CRADD isoform X1. (199 aa)
CAAP1Caspase activity and apoptosis inhibitor 1 isoform X1. (364 aa)
MICAL1F-actin-monooxygenase MICAL1 isoform X1. (1067 aa)
PMAIP1Phorbol-12-myristate-13-acetate-induced protein 1. (54 aa)
NOD1Nucleotide-binding oligomerization domain-containing protein 1 isoform X1. (963 aa)
PRDX3Thioredoxin-dependent peroxide reductase, mitochondrial. (257 aa)
NAIPBaculoviral IAP repeat-containing protein 1 isoform X1. (1402 aa)
BCAP31B-cell receptor-associated protein 31. (245 aa)
USP47Ubiquitin carboxyl-terminal hydrolase 47 isoform X1; Belongs to the peptidase C19 family. (1355 aa)
CASP8Caspase-8 isoform X1; Belongs to the peptidase C14A family. (497 aa)
CFLARCASP8 and FADD-like apoptosis regulator isoform X1; Belongs to the peptidase C14A family. (532 aa)
LOC112407979Secreted frizzled-related protein 2-like. (105 aa)
CASP10Caspase-10; Belongs to the peptidase C14A family. (517 aa)
CASP2Caspase-2 isoform X1; Belongs to the peptidase C14A family. (452 aa)
LOC112407988Secreted frizzled-related protein 2. (294 aa)
DIABLODiablo homolog, mitochondrial. (237 aa)
HIP1RHuntingtin-interacting protein 1-related protein isoform X1. (1043 aa)
RNF34E3 ubiquitin-protein ligase RNF34. (376 aa)
AIFM1Apoptosis-inducing factor 1, mitochondrial. (613 aa)
APAF1Apoptotic protease-activating factor 1 isoform X1. (1301 aa)
MAP3K5Mitogen-activated protein kinase kinase kinase 5 isoform X2. (1366 aa)
DDX3XATP-dependent RNA helicase DDX3X isoform X1; Belongs to the DEAD box helicase family. (662 aa)
TFAP4Transcription factor AP-4. (334 aa)
BIRC3Baculoviral IAP repeat-containing protein 3. (604 aa)
BIRC2Baculoviral IAP repeat-containing protein 2. (620 aa)
BOKBcl-2-related ovarian killer protein. (246 aa)
BIRC5Baculoviral IAP repeat-containing protein 5. (142 aa)
PMLProtein PML isoform X1. (965 aa)
GSNGelsolin isoform X1. (770 aa)
TNFSF15Tumor necrosis factor ligand superfamily member 15 isoform X1. (256 aa)
CARD9Caspase recruitment domain-containing protein 9 isoform X2. (539 aa)
VIL1Villin-1. (827 aa)
GPER1G-protein coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (358 aa)
PPM1FProtein phosphatase 1F isoform X1. (433 aa)
INTS1Integrator complex subunit 1. (2024 aa)
HTRA2Serine protease HTRA2, mitochondrial. (458 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
DLC1Rho GTPase-activating protein 7 isoform X1. (1528 aa)
MTCH1Mitochondrial carrier homolog 1 isoform X1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (395 aa)
BAK1Bcl-2 homologous antagonist/killer isoform X1. (239 aa)
SIRT1NAD-dependent protein deacetylase sirtuin-1 isoform X1. (557 aa)
RPS6KA1Ribosomal protein S6 kinase. (744 aa)
NODALNodal homolog. (348 aa)
LAPTM5Lysosomal-associated transmembrane protein 5. (264 aa)
LCKTyrosine-protein kinase. (509 aa)
SFN14-3-3 protein sigma; Belongs to the 14-3-3 family. (248 aa)
DAPDeath-associated protein 1. (102 aa)
YJEFN3yjeF N-terminal domain-containing protein 3. (249 aa)
BCL10B-cell lymphoma/leukemia 10. (233 aa)
NDUFA13LOW QUALITY PROTEIN: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13. (164 aa)
CYR61Protein CYR61. (382 aa)
RACK1Receptor of activated protein C kinase 1. (317 aa)
Your Current Organism:
Neophocaena asiaeorientalis
NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise
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