STRINGSTRING
MAP4K2 MAP4K2 MAP3K10 MAP3K10 MAP3K13 MAP3K13 DVL3 DVL3 FGD2 FGD2 EDN1 EDN1 EPHA4 EPHA4 FZD4 FZD4 TRAF2 TRAF2 DAB2IP DAB2IP RPS3 RPS3 ERN1 ERN1 AXIN1 AXIN1 TAOK3 TAOK3 MAP3K5 MAP3K5 FZD10 FZD10 LOC112408460 LOC112408460 TNFRSF11A TNFRSF11A CCL19 CCL19 TRAF6 TRAF6 PTPN1 PTPN1 PAK1 PAK1 MAP3K11 MAP3K11 SASH1 SASH1 MAP3K4 MAP3K4 WNT5A WNT5A ERN2 ERN2 FZD5 FZD5 AGER AGER MAP3K12 MAP3K12 MAP3K7 MAP3K7 SYK SYK DVL2 DVL2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MAP4K2Non-specific serine/threonine protein kinase; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. (894 aa)
MAP3K10Mitogen-activated protein kinase kinase kinase. (898 aa)
MAP3K13Mitogen-activated protein kinase kinase kinase 13; Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. (966 aa)
DVL3Segment polarity protein dishevelled homolog DVL-3 isoform X1. (716 aa)
FGD2FYVE, RhoGEF and PH domain-containing protein 2 isoform X1. (697 aa)
EDN1Endothelin-1. (202 aa)
EPHA4Ephrin type-A receptor 4 isoform X1. (986 aa)
FZD4Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (516 aa)
DAB2IPDisabled homolog 2-interacting protein isoform X1. (1071 aa)
RPS340S ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (243 aa)
ERN1Serine/threonine-protein kinase/endoribonuclease IRE1. (858 aa)
AXIN1Axin-1 isoform X1. (866 aa)
TAOK3Serine/threonine-protein kinase TAO3. (898 aa)
MAP3K5Mitogen-activated protein kinase kinase kinase 5 isoform X2. (1366 aa)
FZD10Frizzled-10; Belongs to the G-protein coupled receptor Fz/Smo family. (581 aa)
LOC112408460Rho guanine nucleotide exchange factor 5-like isoform X1. (1589 aa)
TNFRSF11ATumor necrosis factor receptor superfamily member 11A. (689 aa)
CCL19C-C motif chemokine. (174 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (570 aa)
PTPN1Tyrosine-protein phosphatase non-receptor type. (424 aa)
PAK1Non-specific serine/threonine protein kinase. (544 aa)
MAP3K11Mitogen-activated protein kinase kinase kinase 11. (561 aa)
SASH1SAM and SH3 domain-containing protein 1 isoform X1. (1200 aa)
MAP3K4Mitogen-activated protein kinase kinase kinase 4 isoform X1. (1598 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
ERN2Serine/threonine-protein kinase/endoribonuclease IRE2 isoform X1. (927 aa)
FZD5Frizzled-5; Belongs to the G-protein coupled receptor Fz/Smo family. (555 aa)
AGERAdvanced glycosylation end product-specific receptor isoform X1. (513 aa)
MAP3K12Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway. (875 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
SYKTyrosine-protein kinase. (626 aa)
DVL2Segment polarity protein dishevelled homolog DVL-2 isoform X1. (785 aa)
Your Current Organism:
Neophocaena asiaeorientalis
NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise
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