STRINGSTRING
PPP2R2D PPP2R2D ANAPC2 ANAPC2 PPP6C PPP6C TMOD3 TMOD3 MASTL MASTL CCNE1 CCNE1 FBXL8 FBXL8 FBXL22 FBXL22 CCNB2 CCNB2 FBXL15 FBXL15 ACVR1B ACVR1B PPP3CA PPP3CA EIF4E EIF4E WNT10B WNT10B CDK2 CDK2 E2F6 E2F6 E2F7 E2F7 KLF11 KLF11 SMC5 SMC5 USP26 USP26 E2F3 E2F3 CHEK1 CHEK1 POLE POLE FBXL7 FBXL7 PLK3 PLK3 USP37 USP37 CDK14 CDK14 CDK1 CDK1 PLK2 PLK2 CCNO CCNO EIF4EBP1 EIF4EBP1 TAF2 TAF2 CHMP2A CHMP2A FBXL6 FBXL6 MYC MYC EZH2 EZH2 CCNY CCNY CDC25B CDC25B E2F1 E2F1 FBXL17 FBXL17 TRIM71 TRIM71 ANAPC1 ANAPC1 KDM8 KDM8 CCNB3 CCNB3 PLK1 PLK1 CCNA2 CCNA2 FBXL12 FBXL12 NASP NASP UBE2C UBE2C LATS1 LATS1 CCNI2 CCNI2 IQGAP3 IQGAP3 CHMP7 CHMP7 CKS1B CKS1B NES NES CDK16 CDK16 CCND1 CCND1 CCNJL CCNJL CDK18 CDK18 ZPR1 ZPR1 CDC25A CDC25A NEUROG1 NEUROG1 HINFP HINFP CDC23 CDC23 CDC25C CDC25C CDC16 CDC16 TFDP1 TFDP1 BACH1 BACH1 CCNG1 CCNG1 KAT14 KAT14 LATS2 LATS2 LOC112404902 LOC112404902 CCNI CCNI CCNG2 CCNG2 FBXL3 FBXL3 SOWAHB SOWAHB CDK5 CDK5 MTA3 MTA3 CDK17 CDK17 SKP2 SKP2 CTDP1 CTDP1 LOC112405971 LOC112405971 BCL2 BCL2 LOC112406614 LOC112406614 CCNA1 CCNA1 CACUL1 CACUL1 UBE2S UBE2S CCNB1 CCNB1 RB1 RB1 TAF10 TAF10 CCNE2 CCNE2 LOC112407960 LOC112407960 CDK15 CDK15 RPS6KB1 RPS6KB1 RBBP8 RBBP8 RCC1 RCC1 LOC112414495 LOC112414495 EPS8 EPS8 CCND2 CCND2 E2F4 E2F4 SPAST SPAST CDKN1B CDKN1B USH1C USH1C APP APP BUB1B BUB1B CKS2 CKS2 SPDYA SPDYA PHF8 PHF8 CNTD2 CNTD2 CHEK2 CHEK2 PIM2 PIM2 FOXM1 FOXM1 LOC112415834 LOC112415834 PPM1D PPM1D ANAPC7 ANAPC7 GPR132 GPR132 TPD52L1 TPD52L1 RPL24 RPL24 CDC27 CDC27 BIRC5 BIRC5 LZTS1 LZTS1 ENSA ENSA CCND3 CCND3 ITGB1 ITGB1 SIRT7 SIRT7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PPP2R2DSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (449 aa)
ANAPC2Anaphase-promoting complex subunit 2; Belongs to the cullin family. (741 aa)
PPP6CSerine/threonine-protein phosphatase. (305 aa)
TMOD3Tropomodulin-3. (352 aa)
MASTLSerine/threonine-protein kinase greatwall isoform X3. (887 aa)
CCNE1G1/S-specific cyclin-E1; Belongs to the cyclin family. (410 aa)
FBXL8F-box/LRR-repeat protein 8. (374 aa)
FBXL22F-box and leucine-rich protein 22. (226 aa)
CCNB2G2/mitotic-specific cyclin-B2 isoform X1; Belongs to the cyclin family. (398 aa)
FBXL15F-box/LRR-repeat protein 15 isoform X1. (300 aa)
ACVR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (453 aa)
PPP3CASerine/threonine-protein phosphatase. (511 aa)
EIF4EEukaryotic translation initiation factor 4E; Belongs to the eukaryotic initiation factor 4E family. (303 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
CDK2Cyclin-dependent kinase 2 isoform X1; Belongs to the protein kinase superfamily. (346 aa)
E2F6Transcription factor E2F6 isoform X1. (441 aa)
E2F7Transcription factor E2F7. (905 aa)
KLF11Krueppel-like factor 11 isoform X1. (517 aa)
SMC5Structural maintenance of chromosomes protein 5 isoform X1. (1106 aa)
USP26Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (918 aa)
E2F3Transcription factor E2F3. (349 aa)
CHEK1Serine/threonine-protein kinase Chk1; Belongs to the protein kinase superfamily. (476 aa)
POLEDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2279 aa)
FBXL7F-box/LRR-repeat protein 7. (491 aa)
PLK3Serine/threonine-protein kinase PLK. (647 aa)
USP37Ubiquitin carboxyl-terminal hydrolase 37 isoform X1; Belongs to the peptidase C19 family. (992 aa)
CDK14Cyclin-dependent kinase 14; Belongs to the protein kinase superfamily. (469 aa)
CDK1Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily. (297 aa)
PLK2Serine/threonine-protein kinase PLK. (685 aa)
CCNOcyclin-O; Belongs to the cyclin family. (348 aa)
EIF4EBP1Eukaryotic translation initiation factor 4E-binding protein 1. (118 aa)
TAF2Transcription initiation factor TFIID subunit 2 isoform X1. (1251 aa)
CHMP2ACharged multivesicular body protein 2a isoform X1. (305 aa)
FBXL6F-box/LRR-repeat protein 6. (546 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (439 aa)
EZH2Histone-lysine N-methyltransferase EZH2 isoform X1. (751 aa)
CCNYcyclin-Y isoform X1; Belongs to the cyclin family. (302 aa)
CDC25BM-phase inducer phosphatase 2 isoform X1. (574 aa)
E2F1Transcription factor E2F1. (360 aa)
FBXL17LOW QUALITY PROTEIN: F-box/LRR-repeat protein 17. (686 aa)
TRIM71E3 ubiquitin-protein ligase TRIM71. (596 aa)
ANAPC1Anaphase-promoting complex subunit 1 isoform X1. (1948 aa)
KDM8jmjC domain-containing protein 5. (406 aa)
CCNB3G2/mitotic-specific cyclin-B3; Belongs to the cyclin family. (1245 aa)
PLK1Serine/threonine-protein kinase PLK. (597 aa)
CCNA2cyclin-A2; Belongs to the cyclin family. (432 aa)
FBXL12F-box/LRR-repeat protein 12 isoform X1. (326 aa)
NASPNuclear autoantigenic sperm protein isoform X1. (778 aa)
UBE2CUbiquitin-conjugating enzyme E2 C isoform X1; Belongs to the ubiquitin-conjugating enzyme family. (203 aa)
LATS1Serine/threonine-protein kinase LATS1. (1128 aa)
CCNI2cyclin-I2; Belongs to the cyclin family. (293 aa)
IQGAP3Ras GTPase-activating-like protein IQGAP3. (1633 aa)
CHMP7Charged multivesicular body protein 7. (450 aa)
CKS1BCyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa)
NESLOW QUALITY PROTEIN: nestin; Belongs to the intermediate filament family. (1538 aa)
CDK16Cyclin-dependent kinase 16; Belongs to the protein kinase superfamily. (496 aa)
CCND1G1/S-specific cyclin-D1; Belongs to the cyclin family. (295 aa)
CCNJLcyclin-J-like protein; Belongs to the cyclin family. (388 aa)
CDK18LOW QUALITY PROTEIN: cyclin-dependent kinase 18. (470 aa)
ZPR1Zinc finger protein ZPR1. (459 aa)
CDC25AM-phase inducer phosphatase 1 isoform X1. (524 aa)
NEUROG1Neurogenin-1. (244 aa)
HINFPHistone H4 transcription factor isoform X1. (522 aa)
CDC23Cell division cycle protein 23 homolog. (597 aa)
CDC25CM-phase inducer phosphatase 3 isoform X1. (500 aa)
CDC16Cell division cycle protein 16 homolog isoform X1. (741 aa)
TFDP1Transcription factor. (410 aa)
BACH1Transcription regulator protein BACH1 isoform X1. (744 aa)
CCNG1cyclin-G1; Belongs to the cyclin family. (295 aa)
KAT14Cysteine-rich protein 2-binding protein isoform X1. (784 aa)
LATS2Serine/threonine-protein kinase LATS2. (805 aa)
LOC112404902LOW QUALITY PROTEIN: baculoviral IAP repeat-containing protein 5-like. (215 aa)
CCNIcyclin-I; Belongs to the cyclin family. (377 aa)
CCNG2cyclin-G2; Belongs to the cyclin family. (344 aa)
FBXL3F-box/LRR-repeat protein 3. (429 aa)
SOWAHBAnkyrin repeat domain-containing protein SOWAHB. (662 aa)
CDK5Cyclin-dependent-like kinase 5; Belongs to the protein kinase superfamily. (292 aa)
MTA3Metastasis-associated protein MTA3 isoform X1. (538 aa)
CDK17Cyclin-dependent kinase 17. (523 aa)
SKP2S-phase kinase-associated protein 2 isoform X1. (436 aa)
CTDP1RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (974 aa)
LOC112405971Histone lysine demethylase PHF8-like. (177 aa)
BCL2Apoptosis regulator Bcl-2 isoform X1. (233 aa)
LOC112406614LOW QUALITY PROTEIN: eukaryotic translation initiation factor 4E-like; Belongs to the eukaryotic initiation factor 4E family. (217 aa)
CCNA1cyclin-A1; Belongs to the cyclin family. (421 aa)
CACUL1CDK2-associated and cullin domain-containing protein 1; Belongs to the cullin family. (367 aa)
UBE2SUbiquitin-conjugating enzyme E2 S; Belongs to the ubiquitin-conjugating enzyme family. (223 aa)
CCNB1G2/mitotic-specific cyclin-B1; Belongs to the cyclin family. (433 aa)
RB1Retinoblastoma-associated protein. (816 aa)
TAF10Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (152 aa)
CCNE2G1/S-specific cyclin-E2; Belongs to the cyclin family. (404 aa)
LOC112407960LOW QUALITY PROTEIN: DNA endonuclease RBBP8-like. (968 aa)
CDK15Cyclin-dependent kinase 15 isoform X1; Belongs to the protein kinase superfamily. (435 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)
RBBP8DNA endonuclease RBBP8 isoform X1. (889 aa)
RCC1Regulator of chromosome condensation isoform X2. (457 aa)
LOC112414495Protein NPAT isoform X1. (1445 aa)
EPS8Epidermal growth factor receptor kinase substrate 8 isoform X1. (835 aa)
CCND2G1/S-specific cyclin-D2; Belongs to the cyclin family. (289 aa)
E2F4Transcription factor E2F4 isoform X1. (405 aa)
SPASTSpastin; ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Severing activity is not dependent on tubulin acetylation or detyrosination. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation [...] (616 aa)
CDKN1BCyclin-dependent kinase inhibitor 1B. (198 aa)
USH1CHarmonin. (551 aa)
APPAmyloid-beta A4 protein isoform X1. (767 aa)
BUB1BMitotic checkpoint serine/threonine-protein kinase BUB1 beta. (1062 aa)
CKS2Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa)
SPDYASpeedy protein A. (312 aa)
PHF8Histone lysine demethylase PHF8. (846 aa)
CNTD2Cyclin N-terminal domain-containing protein 2 isoform X2; Belongs to the cyclin family. (308 aa)
CHEK2Serine/threonine-protein kinase Chk2. (544 aa)
PIM2Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (313 aa)
FOXM1Forkhead box protein M1. (761 aa)
LOC112415834LOW QUALITY PROTEIN: protein CC2D2B-like; Belongs to the cyclin family. (1540 aa)
PPM1DProtein phosphatase 1D. (605 aa)
ANAPC7LOW QUALITY PROTEIN: anaphase-promoting complex subunit 7. (596 aa)
GPR132Probable G-protein coupled receptor 132; Belongs to the G-protein coupled receptor 1 family. (342 aa)
TPD52L1Tumor protein D53 isoform X1. (204 aa)
RPL2460S ribosomal protein L24. (157 aa)
CDC27Cell division cycle protein 27 homolog isoform X1. (825 aa)
BIRC5Baculoviral IAP repeat-containing protein 5. (142 aa)
LZTS1Leucine zipper putative tumor suppressor 1. (591 aa)
ENSAAlpha-endosulfine; Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. Belongs to the endosulfine family. (121 aa)
CCND3G1/S-specific cyclin-D3 isoform X3; Belongs to the cyclin family. (358 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
SIRT7NAD-dependent protein deacetylase sirtuin-7. (400 aa)
Your Current Organism:
Neophocaena asiaeorientalis
NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise
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