STRINGSTRING
IQGAP2 IQGAP2 ARPC1A ARPC1A MAGEL2 MAGEL2 WHAMM WHAMM SPIRE1 SPIRE1 GSN GSN ARPC2 ARPC2 VIL1 VIL1 ARPC5L ARPC5L ARPC4 ARPC4 LOC112412569 LOC112412569 ARPC3 ARPC3 LMOD3 LMOD3 LMOD1 LMOD1 ACTR2 ACTR2 FMN2 FMN2 JMY JMY EVL EVL LMOD2 LMOD2 ARPC1B ARPC1B ACTR3B ACTR3B ACTR3 ACTR3 SPIRE2 SPIRE2 WASHC1 WASHC1 ARPC5 ARPC5 FMN1 FMN1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IQGAP2Ras GTPase-activating-like protein IQGAP2 isoform X1. (1575 aa)
ARPC1AActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (388 aa)
MAGEL2MAGE-like protein 2. (1192 aa)
WHAMMWASP homolog-associated protein with actin, membranes and microtubules. (673 aa)
SPIRE1Protein spire homolog 1 isoform X1. (641 aa)
GSNGelsolin isoform X1. (770 aa)
ARPC2Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (300 aa)
VIL1Villin-1. (827 aa)
ARPC5LActin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (101 aa)
ARPC4Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (168 aa)
LOC112412569Zinc finger protein RFP. (513 aa)
ARPC3Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (178 aa)
LMOD3Leiomodin-3. (564 aa)
LMOD1Leiomodin-1. (527 aa)
ACTR2Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (394 aa)
FMN2Formin-2. (826 aa)
JMYJunction-mediating and -regulatory protein. (988 aa)
EVLena/VASP-like protein; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family. (371 aa)
LMOD2Leiomodin-2. (513 aa)
ARPC1BActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (372 aa)
ACTR3BActin-related protein 3B isoform X1; Belongs to the actin family. (534 aa)
ACTR3Actin-related protein 3; Belongs to the actin family. (418 aa)
SPIRE2Protein spire homolog 2 isoform X1. (747 aa)
WASHC1WASH complex subunit 1 isoform X1. (480 aa)
ARPC5Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (151 aa)
FMN1Formin-1 isoform X1. (1420 aa)
Your Current Organism:
Neophocaena asiaeorientalis
NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise
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