STRINGSTRING
LOC112391834 LOC112391834 SMAD3 SMAD3 PKD2 PKD2 IFNG IFNG MMP8 MMP8 DDAH2 DDAH2 PTX3 PTX3 IL1B IL1B ASL ASL INSR INSR ESR1 ESR1 AGXT2 AGXT2 HSP90AA1 HSP90AA1 ASS1 ASS1 KLF2 KLF2 DDAH1 DDAH1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC112391834C-type lectin domain family 7 member A-like isoform X1. (244 aa)
SMAD3Mothers against decapentaplegic homolog. (376 aa)
PKD2Polycystin-2 isoform X1. (782 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa)
MMP8Neutrophil collagenase isoform X1. (468 aa)
DDAH2N(G),N(G)-dimethylarginine dimethylaminohydrolase 2. (286 aa)
PTX3Pentraxin-related protein PTX3. (382 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (266 aa)
ASLArgininosuccinate lyase. (464 aa)
INSRTyrosine-protein kinase receptor. (1382 aa)
ESR1Estrogen receptor. (604 aa)
AGXT2Alanine--glyoxylate aminotransferase 2, mitochondrial isoform X1; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (514 aa)
HSP90AA1Heat shock protein HSP 90-alpha. (733 aa)
ASS1Argininosuccinate synthase. (412 aa)
KLF2Krueppel-like factor 2. (222 aa)
DDAH1N(G),N(G)-dimethylarginine dimethylaminohydrolase 1. (282 aa)
Your Current Organism:
Neophocaena asiaeorientalis
NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise
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