(14 nodes) Positive regulation of B cell differentiation network (Neophocaena asiaeorientalis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	XBP1	LOW QUALITY PROTEIN: X-box-binding protein 1. (379 aa)
	SYK	Tyrosine-protein kinase. (626 aa)
	CD27	CD27 antigen. (251 aa)
	LOC112392034	Signal transducer and activator of transcription 5A-like. (105 aa)
	NCKAP1L	Nck-associated protein 1-like isoform X1. (1156 aa)
	INPP5D	Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1. (1187 aa)
	MMP14	Matrix metalloproteinase-14. (582 aa)
	STAT5A	Signal transducer and activator of transcription. (726 aa)
	LOC112399174	Signal transducer and activator of transcription. (618 aa)
	BAD	Bcl2-associated agonist of cell death. (168 aa)
	IL7	Interleukin-7 isoform X1. (226 aa)
	PCID2	PCI domain-containing protein 2. (399 aa)
	IL2RG	Cytokine receptor common subunit gamma isoform X1. (381 aa)
	PPP2R3C	Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma isoform X1. (453 aa)

Your Current Organism:

Neophocaena asiaeorientalis

NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CD27	IL7	A0A341AHB7	A0A341BYR1	CD27 antigen.	Interleukin-7 isoform X1.	0.542
CD27	SYK	A0A341AHB7	A0A341ADP3	CD27 antigen.	Tyrosine-protein kinase.	0.437
CD27	XBP1	A0A341AHB7	A0A341DCI1	CD27 antigen.	LOW QUALITY PROTEIN: X-box-binding protein 1.	0.410
IL2RG	IL7	A0A341CGZ6	A0A341BYR1	Cytokine receptor common subunit gamma isoform X1.	Interleukin-7 isoform X1.	0.974
IL2RG	LOC112392034	A0A341CGZ6	A0A341AJR2	Cytokine receptor common subunit gamma isoform X1.	Signal transducer and activator of transcription 5A-like.	0.814
IL2RG	LOC112399174	A0A341CGZ6	A0A341BE08	Cytokine receptor common subunit gamma isoform X1.	Signal transducer and activator of transcription.	0.902
IL2RG	STAT5A	A0A341CGZ6	A0A341BAX0	Cytokine receptor common subunit gamma isoform X1.	Signal transducer and activator of transcription.	0.901
IL2RG	SYK	A0A341CGZ6	A0A341ADP3	Cytokine receptor common subunit gamma isoform X1.	Tyrosine-protein kinase.	0.447
IL7	CD27	A0A341BYR1	A0A341AHB7	Interleukin-7 isoform X1.	CD27 antigen.	0.542
IL7	IL2RG	A0A341BYR1	A0A341CGZ6	Interleukin-7 isoform X1.	Cytokine receptor common subunit gamma isoform X1.	0.974
IL7	STAT5A	A0A341BYR1	A0A341BAX0	Interleukin-7 isoform X1.	Signal transducer and activator of transcription.	0.626
INPP5D	NCKAP1L	A0A341B0F6	A0A341ARD7	Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1.	Nck-associated protein 1-like isoform X1.	0.592
LOC112392034	IL2RG	A0A341AJR2	A0A341CGZ6	Signal transducer and activator of transcription 5A-like.	Cytokine receptor common subunit gamma isoform X1.	0.814
LOC112392034	STAT5A	A0A341AJR2	A0A341BAX0	Signal transducer and activator of transcription 5A-like.	Signal transducer and activator of transcription.	0.984
LOC112399174	IL2RG	A0A341BE08	A0A341CGZ6	Signal transducer and activator of transcription.	Cytokine receptor common subunit gamma isoform X1.	0.902
LOC112399174	STAT5A	A0A341BE08	A0A341BAX0	Signal transducer and activator of transcription.	Signal transducer and activator of transcription.	0.985
NCKAP1L	INPP5D	A0A341ARD7	A0A341B0F6	Nck-associated protein 1-like isoform X1.	Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1.	0.592
STAT5A	IL2RG	A0A341BAX0	A0A341CGZ6	Signal transducer and activator of transcription.	Cytokine receptor common subunit gamma isoform X1.	0.901
STAT5A	IL7	A0A341BAX0	A0A341BYR1	Signal transducer and activator of transcription.	Interleukin-7 isoform X1.	0.626
STAT5A	LOC112392034	A0A341BAX0	A0A341AJR2	Signal transducer and activator of transcription.	Signal transducer and activator of transcription 5A-like.	0.984