(70 nodes) Positive regulation of T cell differentiation network (Neophocaena asiaeorientalis)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	SOX13	Transcription factor SOX-13. (592 aa)
	DUSP10	Dual specificity protein phosphatase 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (482 aa)
	LOC112403425	Protein kinase C zeta type-like. (85 aa)
	ZBTB16	Zinc finger and BTB domain-containing protein 16. (673 aa)
	LOC112404035	NF-kappa-B-activating protein-like. (379 aa)
	IL7	Interleukin-7 isoform X1. (226 aa)
	SOCS5	Suppressor of cytokine signaling 5. (536 aa)
	CCL19	C-C motif chemokine. (174 aa)
	GIMAP5	GTPase IMAP family member 5. (307 aa)
	MALT1	Mucosa-associated lymphoid tissue lymphoma translocation protein 1. (832 aa)
	IL7R	Interleukin-7 receptor subunit alpha. (459 aa)
	LOC112406730	AP-3 complex subunit beta-1-like. (266 aa)
	FOXO3	Forkhead box protein O3. (672 aa)
	RIPK2	Receptor-interacting serine/threonine-protein kinase 2. (387 aa)
	IL2RG	Cytokine receptor common subunit gamma isoform X1. (381 aa)
	SASH3	SAM and SH3 domain-containing protein 3. (380 aa)
	NFKBIZ	NF-kappa-B inhibitor zeta. (725 aa)
	VNN1	Pantetheinase. (495 aa)
	MYB	Transcriptional activator Myb isoform X4. (761 aa)
	PRKCZ	LOW QUALITY PROTEIN: protein kinase C zeta type; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (546 aa)
	ADAM8	Disintegrin and metalloproteinase domain-containing protein 8 isoform X1. (843 aa)
	IHH	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (410 aa)
	CD83	CD83 antigen. (195 aa)
	PTPRC	Receptor-type tyrosine-protein phosphatase C isoform X1. (1258 aa)
	BCL6	B-cell lymphoma 6 protein. (706 aa)
	TGFB1	Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa)
	IL4I1	L-amino-acid oxidase. (588 aa)
	XBP1	LOW QUALITY PROTEIN: X-box-binding protein 1. (379 aa)
	CD27	CD27 antigen. (251 aa)
	AP3B1	AP-3 complex subunit beta-1. (798 aa)
	GLI3	Transcriptional activator GLI3. (1587 aa)
	SHB	LOW QUALITY PROTEIN: SH2 domain-containing adapter protein B. (649 aa)
	LOC112392034	Signal transducer and activator of transcription 5A-like. (105 aa)
	IFNG	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa)
	IL23A	Interleukin-23 subunit alpha. (189 aa)
	NCKAP1L	Nck-associated protein 1-like isoform X1. (1156 aa)
	WNT10B	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
	RHOA	Transforming protein RhoA. (193 aa)
	SHH	Sonic hedgehog protein. (328 aa)
	ITPKB	Kinase; Belongs to the inositol phosphokinase (IPK) family. (939 aa)
	VSIR	V-type immunoglobulin domain-containing suppressor of T-cell activation. (310 aa)
	ANXA1	Annexin. (346 aa)
	ZMIZ1	Zinc finger MIZ domain-containing protein 1. (1065 aa)
	LEF1	Lymphoid enhancer-binding factor 1 isoform X1. (414 aa)
	RARA	LOW QUALITY PROTEIN: retinoic acid receptor alpha. (572 aa)
	IL36B	Interleukin-1. (118 aa)
	LOC112398972	Tyrosine-protein kinase. (612 aa)
	IL1RL2	Interleukin-1 receptor-like 2 isoform X1. (600 aa)
	SOCS1	Suppressor of cytokine signaling 1. (214 aa)
	LOC112399174	Signal transducer and activator of transcription. (618 aa)
	FOXP3	LOW QUALITY PROTEIN: forkhead box protein P3. (452 aa)
	LOC112399533	Amine oxidase. (529 aa)
	TNFSF9	Tumor necrosis factor ligand superfamily member 9; Belongs to the tumor necrosis factor family. (292 aa)
	EGR3	Early growth response protein 3. (387 aa)
	ADA	Adenosine deaminase isoform X1. (402 aa)
	ZBTB7B	Zinc finger and BTB domain-containing protein 7B. (542 aa)
	KAT5	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (546 aa)
	SART1	U4/U6.U5 tri-snRNP-associated protein 1. (830 aa)
	PIK3R6	Phosphoinositide 3-kinase regulatory subunit 6. (763 aa)
	BAD	Bcl2-associated agonist of cell death. (168 aa)
	HLX	H2.0-like homeobox protein. (486 aa)
	AMBRA1	Activating molecule in BECN1-regulated autophagy protein 1 isoform X2. (1295 aa)
	ZBTB1	Zinc finger and BTB domain-containing protein 1. (713 aa)
	PCK1	Phosphoenolpyruvate carboxykinase, cytosolic [GTP]. (622 aa)
	RHOH	Rho-related GTP-binding protein RhoH. (191 aa)
	GATA3	Trans-acting T-cell-specific transcription factor GATA-3 isoform X1. (444 aa)
	CD74	HLA class II histocompatibility antigen gamma chain isoform X1. (278 aa)
	SYK	Tyrosine-protein kinase. (626 aa)
	LOC112390679	NF-kappa-B-activating protein. (413 aa)
	RASGRP1	RAS guanyl-releasing protein 1 isoform X1. (854 aa)

Your Current Organism:

Neophocaena asiaeorientalis

NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AP3B1	LOC112406730	A0A341AHF2	A0A341C9I6	AP-3 complex subunit beta-1.	AP-3 complex subunit beta-1-like.	0.924
BCL6	CD27	A0A341D7F2	A0A341AHB7	B-cell lymphoma 6 protein.	CD27 antigen.	0.583
BCL6	FOXP3	A0A341D7F2	A0A341BFI0	B-cell lymphoma 6 protein.	LOW QUALITY PROTEIN: forkhead box protein P3.	0.791
BCL6	GATA3	A0A341D7F2	A0A341ABP1	B-cell lymphoma 6 protein.	Trans-acting T-cell-specific transcription factor GATA-3 isoform X1.	0.590
BCL6	IFNG	A0A341D7F2	A0A341APD9	B-cell lymphoma 6 protein.	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	0.630
BCL6	XBP1	A0A341D7F2	A0A341DCI1	B-cell lymphoma 6 protein.	LOW QUALITY PROTEIN: X-box-binding protein 1.	0.736
CCL19	CD83	A0A341C5I7	A0A341CYC2	C-C motif chemokine.	CD83 antigen.	0.511
CCL19	FOXP3	A0A341C5I7	A0A341BFI0	C-C motif chemokine.	LOW QUALITY PROTEIN: forkhead box protein P3.	0.511
CCL19	IFNG	A0A341C5I7	A0A341APD9	C-C motif chemokine.	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	0.741
CCL19	IL7	A0A341C5I7	A0A341BYR1	C-C motif chemokine.	Interleukin-7 isoform X1.	0.545
CD27	BCL6	A0A341AHB7	A0A341D7F2	CD27 antigen.	B-cell lymphoma 6 protein.	0.583
CD27	CD83	A0A341AHB7	A0A341CYC2	CD27 antigen.	CD83 antigen.	0.498
CD27	FOXP3	A0A341AHB7	A0A341BFI0	CD27 antigen.	LOW QUALITY PROTEIN: forkhead box protein P3.	0.681
CD27	GATA3	A0A341AHB7	A0A341ABP1	CD27 antigen.	Trans-acting T-cell-specific transcription factor GATA-3 isoform X1.	0.416
CD27	IFNG	A0A341AHB7	A0A341APD9	CD27 antigen.	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	0.718
CD27	IL1RL2	A0A341AHB7	A0A341BAM9	CD27 antigen.	Interleukin-1 receptor-like 2 isoform X1.	0.517
CD27	IL7	A0A341AHB7	A0A341BYR1	CD27 antigen.	Interleukin-7 isoform X1.	0.542
CD27	IL7R	A0A341AHB7	A0A341C786	CD27 antigen.	Interleukin-7 receptor subunit alpha.	0.491
CD27	LOC112398972	A0A341AHB7	A0A341BA78	CD27 antigen.	Tyrosine-protein kinase.	0.471
CD27	SYK	A0A341AHB7	A0A341ADP3	CD27 antigen.	Tyrosine-protein kinase.	0.437