STRINGSTRING
ROCK1 ROCK1 MEF2C MEF2C LOC112392042 LOC112392042 DLX1 DLX1 GLI3 GLI3 LOC112392728 LOC112392728 LOC112392028 LOC112392028 LOC112392060 LOC112392060 JAG1 JAG1 BMP4 BMP4 ZNF536 ZNF536 ASCL1 ASCL1 LTK LTK HOXD3 HOXD3 APP APP HEY1 HEY1 DLX2 DLX2 PHOX2B PHOX2B ALK ALK NTF3 NTF3 SOCS2 SOCS2 FOXG1 FOXG1 BEND6 BEND6 BCL2 BCL2 LOC112406614 LOC112406614 NR2E1 NR2E1 NKX6-1 NKX6-1 HOXA2 HOXA2 LOC112406359 LOC112406359 HES3 HES3 SOX11 SOX11 LOC112407979 LOC112407979 MMD MMD MIB1 MIB1 NTF4 NTF4 ISL2 ISL2 DPYSL2 DPYSL2 MAP3K13 MAP3K13 EIF4ENIF1 EIF4ENIF1 CALR CALR EIF4G1 EIF4G1 BCL6 BCL6 NEUROD1 NEUROD1 ITGB1 ITGB1 WNT3A WNT3A BMP2 BMP2 FGFR1 FGFR1 SFRP1 SFRP1 LSM1 LSM1 NGF NGF VWC2 VWC2 MMD2 MMD2 VWC2L VWC2L CTDSP1 CTDSP1 NOTCH1 NOTCH1 HMG20A HMG20A CDK5RAP2 CDK5RAP2 SIN3A SIN3A BRINP1 BRINP1 TRIM32 TRIM32 GDPD5 GDPD5 FOXA1 FOXA1 DUOXA1 DUOXA1 HES5 HES5 LRRC45 LRRC45 SOX9 SOX9 EDNRB EDNRB SOX8 SOX8 FGF20 FGF20 HEY2 HEY2 BRINP2 BRINP2 FEZF1 FEZF1 PCP4 PCP4 OLIG2 OLIG2 LOC112407988 LOC112407988 TTC3 TTC3 LBX1 LBX1 POU4F2 POU4F2 NEPRO NEPRO ZFHX3 ZFHX3 EIF4E EIF4E ATOH1 ATOH1 ID2 ID2 GDF11 GDF11 BIN1 BIN1 BRINP3 BRINP3 RHOA RHOA MYCL MYCL FERD3L FERD3L SHH SHH HEYL HEYL BMP6 BMP6 EYA1 EYA1 ISL1 ISL1 LOC112395837 LOC112395837 LRRK2 LRRK2 LOC112396900 LOC112396900 ECT2 ECT2 ZHX2 ZHX2 CDON CDON LMX1A LMX1A MEIS1 MEIS1 MED1 MED1 NREP NREP SPAG9 SPAG9 ADRA2B ADRA2B ADRA2C ADRA2C YWHAG YWHAG FGF2 FGF2 TBX6 TBX6 MOSMO MOSMO DLL1 DLL1 NEUROD2 NEUROD2 FEZF2 FEZF2 REST REST IRX3 IRX3 CNTN4 CNTN4 SIX1 SIX1 CNTF CNTF GDF7 GDF7 BCL11B BCL11B IMPACT IMPACT ARHGEF2 ARHGEF2 GPR37L1 GPR37L1 CASZ1 CASZ1 DISP3 DISP3 LOC112402836 LOC112402836 ZEB1 ZEB1 NKX2-2 NKX2-2 BMP7 BMP7 LOC112403328 LOC112403328 LOC112404011 LOC112404011 CNTN2 CNTN2 PROX1 PROX1 NEUROG1 NEUROG1 DDX6 DDX6 ZC4H2 ZC4H2 HES1 HES1 ZFHX2 ZFHX2 RNF112 RNF112 NKX2-5 NKX2-5 TLX3 TLX3 PAX6 PAX6 DIXDC1 DIXDC1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1354 aa)
MEF2CMyocyte-specific enhancer factor 2C isoform X4. (483 aa)
LOC112392042Protein L-Myc-like. (165 aa)
DLX1Homeobox protein DLX-1 isoform X1. (255 aa)
GLI3Transcriptional activator GLI3. (1587 aa)
LOC112392728Neuferricin isoform X1; Belongs to the cytochrome b5 family. (264 aa)
LOC112392028RE1-silencing transcription factor-like. (305 aa)
LOC112392060Fibroblast growth factor receptor 1-like. (98 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1177 aa)
BMP4Bone morphogenetic protein 4 isoform X1. (420 aa)
ZNF536Zinc finger protein 536. (1300 aa)
ASCL1LOW QUALITY PROTEIN: achaete-scute homolog 1. (228 aa)
LTKLOW QUALITY PROTEIN: leukocyte tyrosine kinase receptor. (880 aa)
HOXD3Homeobox protein Hox-D3 isoform X2. (432 aa)
APPAmyloid-beta A4 protein isoform X1. (767 aa)
HEY1Hairy/enhancer-of-split related with YRPW motif protein 1. (304 aa)
DLX2Homeobox protein DLX-2. (387 aa)
PHOX2BPaired mesoderm homeobox protein 2B. (262 aa)
ALKTyrosine-protein kinase receptor. (1616 aa)
NTF3Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (252 aa)
SOCS2Suppressor of cytokine signaling 2. (198 aa)
FOXG1Forkhead box protein G1. (662 aa)
BEND6BEN domain-containing protein 6 isoform X1. (279 aa)
BCL2Apoptosis regulator Bcl-2 isoform X1. (233 aa)
LOC112406614LOW QUALITY PROTEIN: eukaryotic translation initiation factor 4E-like; Belongs to the eukaryotic initiation factor 4E family. (217 aa)
NR2E1Nuclear receptor subfamily 2 group E member 1. (385 aa)
NKX6-1Homeobox protein Nkx-6.1. (366 aa)
HOXA2Homeobox protein Hox-A2. (409 aa)
LOC112406359Neuroligin-1. (509 aa)
HES3Transcription factor HES-3. (178 aa)
SOX11Transcription factor SOX. (452 aa)
LOC112407979Secreted frizzled-related protein 2-like. (105 aa)
MMDMonocyte to macrophage differentiation factor isoform X1. (238 aa)
MIB1E3 ubiquitin-protein ligase MIB1. (1225 aa)
NTF4Neurotrophin-4; Belongs to the NGF-beta family. (210 aa)
ISL2Insulin gene enhancer protein ISL-2. (359 aa)
DPYSL2Dihydropyrimidinase-related protein 2 isoform X1. (677 aa)
MAP3K13Mitogen-activated protein kinase kinase kinase 13; Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. (966 aa)
EIF4ENIF1Eukaryotic translation initiation factor 4E transporter isoform X1. (1022 aa)
CALRCalreticulin. (417 aa)
EIF4G1Eukaryotic translation initiation factor 4 gamma 1 isoform X1. (1601 aa)
BCL6B-cell lymphoma 6 protein. (706 aa)
NEUROD1Neurogenic differentiation factor. (356 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
BMP2Bone morphogenetic protein 2 isoform X1. (395 aa)
FGFR1Fibroblast growth factor receptor. (722 aa)
SFRP1Secreted frizzled-related protein 1. (296 aa)
LSM1U6 snRNA-associated Sm-like protein LSm1; Plays a role in the degradation of histone mRNAs, the only eukaryotic mRNAs that are not polyadenylated. Probably also part of an LSm subunits-containing complex involved in the general process of mRNA degradation. (133 aa)
NGFBeta-nerve growth factor; Belongs to the NGF-beta family. (241 aa)
VWC2LOW QUALITY PROTEIN: brorin. (304 aa)
MMD2Monocyte to macrophage differentiation factor 2 isoform X1. (278 aa)
VWC2LVon Willebrand factor C domain-containing protein 2-like. (222 aa)
CTDSP1Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1. (261 aa)
NOTCH1LOW QUALITY PROTEIN: neurogenic locus notch homolog protein 1. (2633 aa)
HMG20AHigh mobility group protein 20A. (347 aa)
CDK5RAP2CDK5 regulatory subunit-associated protein 2 isoform X1. (1866 aa)
SIN3APaired amphipathic helix protein Sin3a. (1274 aa)
BRINP1BMP/retinoic acid-inducible neural-specific protein 1. (761 aa)
TRIM32E3 ubiquitin-protein ligase TRIM32. (653 aa)
GDPD5Glycerophosphodiester phosphodiesterase domain-containing protein 5 isoform X1. (629 aa)
FOXA1Hepatocyte nuclear factor 3-alpha. (466 aa)
DUOXA1LOW QUALITY PROTEIN: dual oxidase maturation factor 1. (339 aa)
HES5Transcription factor HES-5. (94 aa)
LRRC45Leucine-rich repeat-containing protein 45 isoform X1. (670 aa)
SOX9Transcription factor SOX-9. (486 aa)
EDNRBEndothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (443 aa)
SOX8Transcription factor SOX-8. (378 aa)
FGF20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa)
HEY2Hairy/enhancer-of-split related with YRPW motif protein 2. (337 aa)
BRINP2BMP/retinoic acid-inducible neural-specific protein 2. (784 aa)
FEZF1Fez family zinc finger protein 1 isoform X1. (468 aa)
PCP4Calmodulin regulator protein PCP4. (62 aa)
OLIG2Oligodendrocyte transcription factor 2. (251 aa)
LOC112407988Secreted frizzled-related protein 2. (294 aa)
TTC3E3 ubiquitin-protein ligase TTC3 isoform X1. (2000 aa)
LBX1Transcription factor LBX1. (281 aa)
POU4F2POU domain protein. (408 aa)
NEPRONucleolus and neural progenitor protein isoform X1. (563 aa)
ZFHX3Zinc finger homeobox protein 3. (3669 aa)
EIF4EEukaryotic translation initiation factor 4E; Belongs to the eukaryotic initiation factor 4E family. (303 aa)
ATOH1Protein atonal homolog 1. (352 aa)
ID2DNA-binding protein inhibitor ID-2. (134 aa)
GDF11Growth/differentiation factor 11. (263 aa)
BIN1Myc box-dependent-interacting protein 1 isoform X1. (521 aa)
BRINP3BMP/retinoic acid-inducible neural-specific protein 3. (766 aa)
RHOATransforming protein RhoA. (193 aa)
MYCLProtein L-Myc. (186 aa)
FERD3LFer3-like protein. (163 aa)
SHHSonic hedgehog protein. (328 aa)
HEYLHairy/enhancer-of-split related with YRPW motif-like protein isoform X1. (357 aa)
BMP6Bone morphogenetic protein 6. (309 aa)
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (589 aa)
ISL1Insulin gene enhancer protein ISL-1. (349 aa)
LOC112395837LOW QUALITY PROTEIN: calreticulin-like. (540 aa)
LRRK2Leucine-rich repeat serine/threonine-protein kinase 2 isoform X1. (2527 aa)
LOC112396900Neuroligin-1-like. (254 aa)
ECT2Protein ECT2 isoform X1. (973 aa)
ZHX2Zinc fingers and homeoboxes protein 2. (838 aa)
CDONCell adhesion molecule-related/down-regulated by oncogenes. (1279 aa)
LMX1ALIM homeobox transcription factor 1-alpha. (382 aa)
MEIS1Homeobox protein Meis1 isoform X1. (465 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1579 aa)
NREPNeuronal regeneration-related protein. (68 aa)
SPAG9C-Jun-amino-terminal kinase-interacting protein 4 isoform X1. (1177 aa)
ADRA2Balpha-2B adrenergic receptor isoform X1. (447 aa)
ADRA2Calpha-2C adrenergic receptor. (518 aa)
YWHAG14-3-3 protein gamma; Belongs to the 14-3-3 family. (247 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (304 aa)
TBX6T-box transcription factor TBX6 isoform X1. (463 aa)
MOSMOUncharacterized protein C16orf52 homolog. (167 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (759 aa)
NEUROD2Neurogenic differentiation factor. (382 aa)
FEZF2Fez family zinc finger protein 2. (458 aa)
RESTRE1-silencing transcription factor isoform X2. (450 aa)
IRX3Iroquois-class homeodomain protein IRX-3. (501 aa)
CNTN4Contactin-4. (1026 aa)
SIX1Homeobox protein SIX1. (284 aa)
CNTFCiliary neurotrophic factor. (200 aa)
GDF7Growth/differentiation factor 7. (381 aa)
BCL11BB-cell lymphoma/leukemia 11B. (740 aa)
IMPACTProtein IMPACT isoform X1. (318 aa)
ARHGEF2Rho guanine nucleotide exchange factor 2 isoform X1. (1175 aa)
GPR37L1Prosaposin receptor GPR37L1. (464 aa)
CASZ1Zinc finger protein castor homolog 1. (1164 aa)
DISP3Protein dispatched homolog 3. (1390 aa)
LOC112402836Zinc finger protein castor homolog 1-like. (447 aa)
ZEB1LOW QUALITY PROTEIN: zinc finger E-box-binding homeobox 1. (1042 aa)
NKX2-2Homeobox protein Nkx-2.2. (273 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
LOC112403328LOW QUALITY PROTEIN: 14-3-3 protein gamma-like; Belongs to the 14-3-3 family. (247 aa)
LOC112404011C-Jun-amino-terminal kinase-interacting protein 4-like. (123 aa)
CNTN2Contactin-2. (1043 aa)
PROX1Prospero homeobox protein 1 isoform X1. (737 aa)
NEUROG1Neurogenin-1. (244 aa)
DDX6Probable ATP-dependent RNA helicase DDX6; Belongs to the DEAD box helicase family. (483 aa)
ZC4H2Zinc finger C4H2 domain-containing protein isoform X1. (224 aa)
HES1Transcription factor HES-1. (280 aa)
ZFHX2Zinc finger homeobox protein 2. (2576 aa)
RNF112RING finger protein 112. (604 aa)
NKX2-5Homeobox protein Nkx-2.5. (323 aa)
TLX3T-cell leukemia homeobox protein 3. (291 aa)
PAX6Paired box protein Pax-6 isoform X1. (493 aa)
DIXDC1Dixin isoform X1. (688 aa)
Your Current Organism:
Neophocaena asiaeorientalis
NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise
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