STRINGSTRING
PPP3CA PPP3CA SMAD1 SMAD1 WNT10B WNT10B BMPR2 BMPR2 BMP6 BMP6 FFAR4 FFAR4 SUCO SUCO WISP1 WISP1 TMEM119 TMEM119 ZHX3 ZHX3 ACVR2A ACVR2A CTHRC1 CTHRC1 FGF2 FGF2 PDLIM7 PDLIM7 FBXO5 FBXO5 LRP5 LRP5 CTNNBIP1 CTNNBIP1 CEBPB CEBPB LTF LTF BMP7 BMP7 DDR2 DDR2 SMAD5 SMAD5 NPNT NPNT CTNNB1 CTNNB1 PRKD1 PRKD1 GDPD2 GDPD2 WWTR1 WWTR1 SCUBE2 SCUBE2 SOX11 SOX11 FBN2 FBN2 ILK ILK FAM46A FAM46A LOC112407979 LOC112407979 LOC112407988 LOC112407988 YAP1 YAP1 ATRAID ATRAID BMP2 BMP2 RUNX2 RUNX2 IL6ST IL6ST SCUBE3 SCUBE3 WDR63 WDR63 CYR61 CYR61 JUND JUND TP63 TP63 BMPR1A BMPR1A IGF1 IGF1 MEF2C MEF2C GLI3 GLI3 LRP3 LRP3 JAG1 JAG1 BMP4 BMP4 BMPR1B BMPR1B FERMT2 FERMT2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PPP3CASerine/threonine-protein phosphatase. (511 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1012 aa)
BMP6Bone morphogenetic protein 6. (309 aa)
FFAR4Free fatty acid receptor 4 isoform X1. (375 aa)
SUCOSUN domain-containing ossification factor isoform X1. (1249 aa)
WISP1WNT1-inducible-signaling pathway protein 1. (281 aa)
TMEM119Transmembrane protein 119 isoform X1. (363 aa)
ZHX3Zinc fingers and homeoboxes protein 3. (953 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (513 aa)
CTHRC1Collagen triple helix repeat-containing protein 1. (244 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (304 aa)
PDLIM7PDZ and LIM domain protein 7 isoform X1. (458 aa)
FBXO5F-box only protein 5 isoform X1. (448 aa)
LRP5Low-density lipoprotein receptor-related protein 5 isoform X1. (1461 aa)
CTNNBIP1Beta-catenin-interacting protein 1. (81 aa)
CEBPBCCAAT/enhancer-binding protein. (346 aa)
LTFLactotransferrin isoform X1; Belongs to the transferrin family. (711 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
DDR2Discoidin domain-containing receptor 2. (820 aa)
SMAD5Mothers against decapentaplegic homolog. (465 aa)
NPNTNephronectin isoform X1. (581 aa)
CTNNB1Catenin beta-1. (781 aa)
PRKD1Serine/threonine-protein kinase D1 isoform X1. (796 aa)
GDPD2Glycerophosphoinositol inositolphosphodiesterase GDPD2. (539 aa)
WWTR1WW domain-containing transcription regulator protein 1. (400 aa)
SCUBE2Signal peptide, CUB and EGF-like domain-containing protein 2. (890 aa)
SOX11Transcription factor SOX. (452 aa)
FBN2Fibrillin-2. (2912 aa)
ILKIntegrin-linked protein kinase isoform X1. (485 aa)
FAM46APutative nucleotidyltransferase FAM46A isoform X1. (451 aa)
LOC112407979Secreted frizzled-related protein 2-like. (105 aa)
LOC112407988Secreted frizzled-related protein 2. (294 aa)
YAP1Transcriptional coactivator YAP1. (416 aa)
ATRAIDAll-trans retinoic acid-induced differentiation factor. (229 aa)
BMP2Bone morphogenetic protein 2 isoform X1. (395 aa)
RUNX2Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (408 aa)
IL6STInterleukin-6 receptor subunit beta. (918 aa)
SCUBE3Signal peptide, CUB and EGF-like domain-containing protein 3 isoform X1. (1009 aa)
WDR63WD repeat-containing protein 63. (924 aa)
CYR61Protein CYR61. (382 aa)
JUNDTranscription factor jun-D. (345 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
IGF1Insulin-like growth factor I isoform X1. (208 aa)
MEF2CMyocyte-specific enhancer factor 2C isoform X4. (483 aa)
GLI3Transcriptional activator GLI3. (1587 aa)
LRP3Low-density lipoprotein receptor-related protein 3. (687 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1177 aa)
BMP4Bone morphogenetic protein 4 isoform X1. (420 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
FERMT2Fermitin family homolog 2. (680 aa)
Your Current Organism:
Neophocaena asiaeorientalis
NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise
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