STRINGSTRING
INO80 INO80 BMPR1A BMPR1A MYOD1 MYOD1 CAPN3 CAPN3 SLC6A3 SLC6A3 IGF1 IGF1 YBX3 YBX3 RIMS1 RIMS1 SEMA4D SEMA4D PEX5 PEX5 FXN FXN MEF2C MEF2C NCBP1 NCBP1 FGF8 FGF8 LOC112392034 LOC112392034 HPN HPN TGFBR1 TGFBR1 TFCP2L1 TFCP2L1 POU4F2 POU4F2 ZFYVE27 ZFYVE27 DERL2 DERL2 PPIB PPIB CXCL16 CXCL16 MKKS MKKS IST1 IST1 WFS1 WFS1 SYT1 SYT1 GLI1 GLI1 CREB1 CREB1 BMPR2 BMPR2 MTPN MTPN BMP10 BMP10 MFSD2A MFSD2A SLC44A4 SLC44A4 TGFB2 TGFB2 LGI1 LGI1 CDKL5 CDKL5 LOC112396076 LOC112396076 EXOSC4 EXOSC4 ACACB ACACB RASAL1 RASAL1 MTM1 MTM1 COMMD5 COMMD5 GHSR GHSR CSF1 CSF1 MMP14 MMP14 TBX5 TBX5 CSNK2A1 CSNK2A1 EFNA5 EFNA5 GHRH GHRH ERBB2 ERBB2 LOC112398445 LOC112398445 CHD7 CHD7 STAT5A STAT5A SYT17 SYT17 LOC112399174 LOC112399174 FGFR1OP FGFR1OP FGF2 FGF2 EXOSC9 EXOSC9 SMURF1 SMURF1 OCM2 OCM2 DLL1 DLL1 HDGFL2 HDGFL2 ZP3 ZP3 INSR INSR DBNL DBNL ARX ARX LIMK1 LIMK1 PRKN PRKN EZR EZR CELF1 CELF1 CRABP2 CRABP2 RFTN1 RFTN1 ACTN3 ACTN3 NTN1 NTN1 SOX15 SOX15 PSMD10 PSMD10 F2 F2 SLC25A33 SLC25A33 MUL1 MUL1 HLX HLX SYT2 SYT2 TBX20 TBX20 CDH4 CDH4 ZPR1 ZPR1 BBS2 BBS2 IL7 IL7 PROX1 PROX1 RAG2 RAG2 N6AMT1 N6AMT1 TRPV2 TRPV2 FGF9 FGF9 DRD2 DRD2 NIPBL NIPBL PLAA PLAA ADNP2 ADNP2 NEDD4L NEDD4L BCL2 BCL2 ZNF639 ZNF639 GHRHR GHRHR GPAM GPAM SHTN1 SHTN1 ZFPM2 ZFPM2 SMAD7 SMAD7 LOC112407442 LOC112407442 GOLGA4 GOLGA4 USP47 USP47 TEAD1 TEAD1 LOC112407979 LOC112407979 TBX2 TBX2 GATA6 GATA6 SYT4 SYT4 LOC112407988 LOC112407988 DSCAM DSCAM WNT2 WNT2 KDM2B KDM2B SASH3 SASH3 POU3F2 POU3F2 DDX3X DDX3X HEY2 HEY2 YAP1 YAP1 SPHK1 SPHK1 RPTOR RPTOR CDKN2AIP CDKN2AIP ADAM10 ADAM10 LOC112410790 LOC112410790 WNT3 WNT3 NOL12 NOL12 BBS4 BBS4 LOC112410331 LOC112410331 ISLR2 ISLR2 ISLR ISLR GPR21 GPR21 SMO SMO SEMA7A SEMA7A TRIM32 TRIM32 EXOSC2 EXOSC2 NOTCH1 NOTCH1 LEP LEP FN1 FN1 VIL1 VIL1 ERBB4 ERBB4 BRAT1 BRAT1 PPM1F PPM1F KLHL22 KLHL22 EDN1 EDN1 TAF9B TAF9B UCN UCN NGF NGF CPNE9 CPNE9 SFRP1 SFRP1 EGFR EGFR CAPN9 CAPN9 WNT3A WNT3A PPARD PPARD PIM1 PIM1 SRF SRF ARMC12 ARMC12 CPNE5 CPNE5 SUPV3L1 SUPV3L1 SFN SFN CIB1 CIB1 AGR2 AGR2 UNC13A UNC13A EIF4G1 EIF4G1 DDX49 DDX49 LPAR3 LPAR3 MAP3K13 MAP3K13 MEGF8 MEGF8 LOC112415435 LOC112415435 SPTBN4 SPTBN4 SYT3 SYT3 PLS1 PLS1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
INO80DNA helicase INO80 isoform X1. (1563 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
MYOD1Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (319 aa)
CAPN3Calpain-3 isoform X4; Belongs to the peptidase C2 family. (773 aa)
SLC6A3Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (617 aa)
IGF1Insulin-like growth factor I isoform X1. (208 aa)
YBX3Y-box-binding protein 3. (348 aa)
RIMS1LOW QUALITY PROTEIN: regulating synaptic membrane exocytosis protein 1. (1574 aa)
SEMA4Dsemaphorin-4D; Belongs to the semaphorin family. (863 aa)
PEX5Peroxisomal biogenesis factor 5 isoform X1. (640 aa)
FXNLOW QUALITY PROTEIN: frataxin, mitochondrial. (244 aa)
MEF2CMyocyte-specific enhancer factor 2C isoform X4. (483 aa)
NCBP1Nuclear cap-binding protein subunit 1. (790 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
LOC112392034Signal transducer and activator of transcription 5A-like. (105 aa)
HPNSerine protease hepsin isoform X1; Belongs to the peptidase S1 family. (417 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (438 aa)
TFCP2L1Transcription factor CP2-like protein 1 isoform X1. (489 aa)
POU4F2POU domain protein. (408 aa)
ZFYVE27Protrudin isoform X1. (406 aa)
DERL2Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (239 aa)
PPIBPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (216 aa)
CXCL16C-X-C motif chemokine 16. (316 aa)
MKKSMcKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin. (570 aa)
IST1IST1 homolog isoform X1. (376 aa)
WFS1Wolframin. (889 aa)
SYT1Synaptotagmin-1. (422 aa)
GLI1Zinc finger protein GLI1 isoform X1. (1106 aa)
CREB1Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1012 aa)
MTPNMyotrophin. (118 aa)
BMP10Bone morphogenetic protein 10. (423 aa)
MFSD2ASodium-dependent lysophosphatidylcholine symporter 1 isoform X1. (529 aa)
SLC44A4Choline transporter-like protein 4; Belongs to the CTL (choline transporter-like) family. (706 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
LGI1Leucine-rich glioma-inactivated protein 1 isoform X1. (641 aa)
CDKL5Cyclin-dependent kinase-like 5. (940 aa)
LOC112396076ATP-dependent RNA helicase DDX3X-like; Belongs to the DEAD box helicase family. (656 aa)
EXOSC4Exosome complex component RRP41. (245 aa)
ACACBacetyl-CoA carboxylase 2. (2456 aa)
RASAL1rasGAP-activating-like protein 1 isoform X1. (838 aa)
MTM1Myotubularin isoform X1. (603 aa)
COMMD5COMM domain-containing protein 5. (224 aa)
GHSRGrowth hormone secretagogue receptor type 1; Belongs to the G-protein coupled receptor 1 family. (366 aa)
CSF1Macrophage colony-stimulating factor 1. (513 aa)
MMP14Matrix metalloproteinase-14. (582 aa)
TBX5T-box transcription factor TBX5. (519 aa)
CSNK2A1Casein kinase II subunit alpha; Belongs to the protein kinase superfamily. (391 aa)
EFNA5ephrin-A5 isoform X1; Belongs to the ephrin family. (228 aa)
GHRHSomatoliberin. (106 aa)
ERBB2Receptor protein-tyrosine kinase. (1255 aa)
LOC112398445Keratin, type I cytoskeletal 17-like isoform X1; Belongs to the intermediate filament family. (449 aa)
CHD7LOW QUALITY PROTEIN: chromodomain-helicase-DNA-binding protein 7. (3000 aa)
STAT5ASignal transducer and activator of transcription. (726 aa)
SYT17Synaptotagmin-17 isoform X1. (505 aa)
LOC112399174Signal transducer and activator of transcription. (618 aa)
FGFR1OPFGFR1 oncogene partner. (434 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (304 aa)
EXOSC9Exosome complex component RRP45. (439 aa)
SMURF1E3 ubiquitin-protein ligase SMURF1. (718 aa)
OCM2Putative oncomodulin-2; Belongs to the parvalbumin family. (109 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (759 aa)
HDGFL2Hepatoma-derived growth factor-related protein 2 isoform X1. (617 aa)
ZP3Zona pellucida sperm-binding protein 3. (421 aa)
INSRTyrosine-protein kinase receptor. (1382 aa)
DBNLDrebrin-like protein isoform X1. (430 aa)
ARXLOW QUALITY PROTEIN: homeobox protein ARX. (445 aa)
LIMK1LIM domain kinase 1. (594 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (465 aa)
EZREzrin. (586 aa)
CELF1CUGBP Elav-like family member 1 isoform X1. (514 aa)
CRABP2Cellular retinoic acid-binding protein 2; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (138 aa)
RFTN1Raftlin. (567 aa)
ACTN3Alpha-actinin-3. (902 aa)
NTN1Netrin-1. (604 aa)
SOX15Protein SOX-15. (231 aa)
PSMD1026S proteasome non-ATPase regulatory subunit 10 isoform X1. (226 aa)
F2Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (623 aa)
SLC25A33Solute carrier family 25 member 33; Belongs to the mitochondrial carrier (TC 2.A.29) family. (321 aa)
MUL1Mitochondrial ubiquitin ligase activator of NFKB 1. (352 aa)
HLXH2.0-like homeobox protein. (486 aa)
SYT2Synaptotagmin-2 isoform X1. (428 aa)
TBX20T-box transcription factor TBX20. (449 aa)
CDH4Cadherin-4 isoform X1; Cadherins are calcium-dependent cell adhesion proteins. (884 aa)
ZPR1Zinc finger protein ZPR1. (459 aa)
BBS2Bardet-Biedl syndrome 2 protein homolog. (721 aa)
IL7Interleukin-7 isoform X1. (226 aa)
PROX1Prospero homeobox protein 1 isoform X1. (737 aa)
RAG2V(D)J recombination-activating protein 2. (527 aa)
N6AMT1hemK methyltransferase family member 2. (214 aa)
TRPV2Transient receptor potential cation channel subfamily V member 2; Belongs to the transient receptor (TC 1.A.4) family. (761 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
DRD2D(2) dopamine receptor isoform X2; Belongs to the G-protein coupled receptor 1 family. (443 aa)
NIPBLNipped-B protein. (2803 aa)
PLAAPhospholipase A-2-activating protein. (796 aa)
ADNP2Activity-dependent neuroprotector homeobox protein 2 isoform X1. (1181 aa)
NEDD4LE3 ubiquitin-protein ligase NEDD4-like isoform X1. (1247 aa)
BCL2Apoptosis regulator Bcl-2 isoform X1. (233 aa)
ZNF639Zinc finger protein 639. (485 aa)
GHRHRGrowth hormone-releasing hormone receptor isoform X1; Belongs to the G-protein coupled receptor 2 family. (456 aa)
GPAMGlycerol-3-phosphate acyltransferase 1, mitochondrial. (877 aa)
SHTN1Shootin-1 isoform X1. (631 aa)
ZFPM2Zinc finger protein ZFPM2. (1150 aa)
SMAD7Mothers against decapentaplegic homolog. (426 aa)
LOC112407442LOW QUALITY PROTEIN: frataxin, mitochondrial-like. (215 aa)
GOLGA4Golgin subfamily A member 4 isoform X5. (2275 aa)
USP47Ubiquitin carboxyl-terminal hydrolase 47 isoform X1; Belongs to the peptidase C19 family. (1355 aa)
TEAD1Transcriptional enhancer factor TEF-1 isoform X1. (436 aa)
LOC112407979Secreted frizzled-related protein 2-like. (105 aa)
TBX2T-box transcription factor TBX2. (588 aa)
GATA6Transcription factor GATA-6. (448 aa)
SYT4Synaptotagmin-4. (425 aa)
LOC112407988Secreted frizzled-related protein 2. (294 aa)
DSCAMDown syndrome cell adhesion molecule. (2039 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
KDM2BLysine-specific demethylase 2B. (1309 aa)
SASH3SAM and SH3 domain-containing protein 3. (380 aa)
POU3F2POU domain protein. (436 aa)
DDX3XATP-dependent RNA helicase DDX3X isoform X1; Belongs to the DEAD box helicase family. (662 aa)
HEY2Hairy/enhancer-of-split related with YRPW motif protein 2. (337 aa)
YAP1Transcriptional coactivator YAP1. (416 aa)
SPHK1Sphingosine kinase 1. (391 aa)
RPTORRegulatory-associated protein of mTOR isoform X1. (1336 aa)
CDKN2AIPCDKN2A-interacting protein isoform X1. (582 aa)
ADAM10Disintegrin and metalloproteinase domain-containing protein 10. (748 aa)
LOC112410790Nucleolar protein 12-like. (137 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (453 aa)
NOL12Nucleolar protein 12. (214 aa)
BBS4Bardet-Biedl syndrome 4 protein isoform X1. (519 aa)
LOC112410331LOW QUALITY PROTEIN: somatotropin-like. (263 aa)
ISLR2Immunoglobulin superfamily containing leucine-rich repeat protein 2. (747 aa)
ISLRImmunoglobulin superfamily containing leucine-rich repeat protein. (429 aa)
GPR21Probable G-protein coupled receptor 21; Belongs to the G-protein coupled receptor 1 family. (349 aa)
SMOSmoothened homolog; Belongs to the G-protein coupled receptor Fz/Smo family. (783 aa)
SEMA7Asemaphorin-7A; Belongs to the semaphorin family. (665 aa)
TRIM32E3 ubiquitin-protein ligase TRIM32. (653 aa)
EXOSC2Exosome complex component RRP4. (293 aa)
NOTCH1LOW QUALITY PROTEIN: neurogenic locus notch homolog protein 1. (2633 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
FN1Fibronectin isoform X5. (2478 aa)
VIL1Villin-1. (827 aa)
ERBB4Receptor protein-tyrosine kinase. (1308 aa)
BRAT1BRCA1-associated ATM activator 1 isoform X1. (869 aa)
PPM1FProtein phosphatase 1F isoform X1. (433 aa)
KLHL22Kelch-like protein 22 isoform X1. (673 aa)
EDN1Endothelin-1. (202 aa)
TAF9BTranscription initiation factor TFIID subunit 9B isoform X1. (259 aa)
UCNUrocortin. (126 aa)
NGFBeta-nerve growth factor; Belongs to the NGF-beta family. (241 aa)
CPNE9Copine-9 isoform X1. (587 aa)
SFRP1Secreted frizzled-related protein 1. (296 aa)
EGFRReceptor protein-tyrosine kinase. (1156 aa)
CAPN9LOW QUALITY PROTEIN: calpain-9; Belongs to the peptidase C2 family. (391 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
PPARDPeroxisome proliferator-activated receptor delta. (441 aa)
PIM1Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (349 aa)
SRFSerum response factor isoform X1. (535 aa)
ARMC12Armadillo repeat-containing protein 12 isoform X2. (366 aa)
CPNE5Copine-5. (593 aa)
SUPV3L1LOW QUALITY PROTEIN: ATP-dependent RNA helicase SUPV3L1, mitochondrial. (776 aa)
SFN14-3-3 protein sigma; Belongs to the 14-3-3 family. (248 aa)
CIB1Calcium and integrin-binding protein 1. (191 aa)
AGR2Anterior gradient protein 2 homolog. (175 aa)
UNC13AProtein unc-13 homolog A. (1647 aa)
EIF4G1Eukaryotic translation initiation factor 4 gamma 1 isoform X1. (1601 aa)
DDX49Probable ATP-dependent RNA helicase DDX49; Belongs to the DEAD box helicase family. (483 aa)
LPAR3Lysophosphatidic acid receptor 3; Belongs to the G-protein coupled receptor 1 family. (355 aa)
MAP3K13Mitogen-activated protein kinase kinase kinase 13; Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. (966 aa)
MEGF8Multiple epidermal growth factor-like domains protein 8. (2784 aa)
LOC112415435LOW QUALITY PROTEIN: CDKN2A-interacting protein-like. (392 aa)
SPTBN4Spectrin beta chain; Belongs to the spectrin family. (2497 aa)
SYT3Synaptotagmin-3. (591 aa)
PLS1Plastin-1 isoform X1. (630 aa)
Your Current Organism:
Neophocaena asiaeorientalis
NCBI taxonomy Id: 1706337
Other names: N. asiaeorientalis asiaeorientalis, Neophocaena asiaeorientalis asiaeorientalis, Yangtze finless porpoise
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